Wac (WW domain containing adaptor with coiled-coil) - Rat Genome Database

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Gene: Wac (WW domain containing adaptor with coiled-coil) Rattus norvegicus
Analyze
Symbol: Wac
Name: WW domain containing adaptor with coiled-coil
RGD ID: 1562407
Description: Predicted to enable RNA polymerase II complex binding activity and chromatin binding activity. Predicted to be involved in several processes, including mitotic G1 DNA damage checkpoint signaling; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; and positive regulation of macroautophagy. Predicted to be located in nucleoplasm. Predicted to be part of spliceosomal complex. Human ortholog(s) of this gene implicated in DeSanto-Shinawi syndrome. Orthologous to human WAC (WW domain containing adaptor with coiled-coil); INTERACTS WITH aflatoxin B1; bisphenol A; DDT.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC307029; RGD1562407; similar to WAC; uncharacterized protein LOC307029; WW domain-containing adapter protein with coiled-coil; WW domain-containing adaptor with coiled-coil
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Wac-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81760,617,702 - 60,677,771 (+)NCBIGRCr8
mRatBN7.21755,922,686 - 55,984,286 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1755,923,123 - 55,982,301 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1759,092,613 - 59,151,089 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01763,095,705 - 63,154,179 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01757,235,586 - 57,293,885 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01760,887,606 - 60,946,630 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1760,888,017 - 60,946,426 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01762,663,721 - 62,723,083 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41764,530,450 - 64,604,845 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1757,238,053 - 57,291,859 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11827461   PMID:21329877   PMID:21811234   PMID:22354037  


Genomics

Comparative Map Data
Wac
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81760,617,702 - 60,677,771 (+)NCBIGRCr8
mRatBN7.21755,922,686 - 55,984,286 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1755,923,123 - 55,982,301 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1759,092,613 - 59,151,089 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01763,095,705 - 63,154,179 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01757,235,586 - 57,293,885 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01760,887,606 - 60,946,630 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1760,888,017 - 60,946,426 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01762,663,721 - 62,723,083 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41764,530,450 - 64,604,845 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1757,238,053 - 57,291,859 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
WAC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381028,532,779 - 28,623,112 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1028,532,493 - 28,623,112 (+)EnsemblGRCh38hg38GRCh38
GRCh371028,821,708 - 28,912,041 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361028,861,706 - 28,949,478 (+)NCBINCBI36Build 36hg18NCBI36
Celera1028,585,512 - 28,673,953 (+)NCBICelera
Cytogenetic Map10p12.1NCBI
HuRef1028,539,551 - 28,629,942 (+)NCBIHuRef
CHM1_11028,821,968 - 28,912,537 (+)NCBICHM1_1
T2T-CHM13v2.01028,563,354 - 28,653,650 (+)NCBIT2T-CHM13v2.0
Wac
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39187,868,614 - 7,929,028 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl187,868,832 - 7,929,028 (+)EnsemblGRCm39 Ensembl
GRCm38187,868,825 - 7,929,028 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl187,868,832 - 7,929,028 (+)EnsemblGRCm38mm10GRCm38
MGSCv37187,868,856 - 7,929,025 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36187,869,237 - 7,927,072 (+)NCBIMGSCv36mm8
Celera187,915,935 - 7,976,189 (+)NCBICelera
Cytogenetic Map18A1NCBI
cM Map184.62NCBI
Wac
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554622,358,842 - 2,435,628 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554622,358,842 - 2,435,644 (+)NCBIChiLan1.0ChiLan1.0
WAC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2841,205,841 - 41,297,561 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11041,211,167 - 41,302,888 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01028,685,294 - 28,777,176 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11029,042,331 - 29,130,597 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1029,042,331 - 29,130,591 (+)Ensemblpanpan1.1panPan2
WAC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1217,504,949 - 17,588,037 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha215,004,769 - 15,088,966 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0215,753,171 - 15,837,460 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1215,191,803 - 15,274,633 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0215,079,183 - 15,162,408 (-)NCBIUNSW_CanFamBas_1.0
Wac
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093448,243,833 - 8,314,148 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366132,794,732 - 2,865,913 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366132,793,706 - 2,862,984 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WAC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1039,932,599 - 40,022,338 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11039,932,562 - 40,024,114 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21044,120,334 - 44,210,098 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WAC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1928,131,774 - 28,222,501 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl928,131,769 - 28,219,134 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605134,167,952 - 34,256,751 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wac
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248056,813,100 - 6,898,686 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Wac
246 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:61
Interacting mature miRNAs:63
Transcripts:ENSRNOT00000058852
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
1358295Aocep1Aortic cell protein QTL 16.10.00000071thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
631497Bp98Blood pressure QTL 983.66arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)174135465160463643Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)174207316069599340Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)174207316069599340Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)175089090860781592Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)175089090860781592Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
2317053Aia25Adjuvant induced arthritis QTL 252.69joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)175090919660781426Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)175402992960463637Rat

Markers in Region
D10S1559  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21755,981,648 - 55,981,773 (-)MAPPERmRatBN7.2
mRatBN7.262,002,659 - 2,002,784 (+)MAPPERmRatBN7.2
mRatBN7.21755,981,648 - 55,981,773 (+)MAPPERmRatBN7.2
mRatBN7.262,002,659 - 2,002,784 (-)MAPPERmRatBN7.2
mRatBN7.21811,855,180 - 11,855,305 (-)MAPPERmRatBN7.2
mRatBN7.21811,855,180 - 11,855,305 (+)MAPPERmRatBN7.2
Rnor_6.01815,628,636 - 15,628,760NCBIRnor6.0
Rnor_6.01760,887,493 - 60,887,617NCBIRnor6.0
Rnor_5.01815,402,667 - 15,402,791UniSTSRnor5.0
Rnor_5.01762,663,608 - 62,663,732UniSTSRnor5.0
RGSC_v3.4616,600,259 - 16,600,383UniSTSRGSC3.4
RGSC_v3.41812,316,769 - 12,316,893UniSTSRGSC3.4
Celera61,804,181 - 1,804,305UniSTS
Celera1811,869,520 - 11,869,644UniSTS
Cytogenetic Map18p12UniSTS
Cytogenetic Map17q12.1UniSTS
RH127461  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21755,984,082 - 55,984,262 (-)MAPPERmRatBN7.2
Rnor_6.01760,883,226 - 60,883,405NCBIRnor6.0
Rnor_5.01762,659,952 - 62,660,131UniSTSRnor5.0
RGSC_v3.41764,593,064 - 64,593,243UniSTSRGSC3.4
Celera1757,297,834 - 57,298,013UniSTS
RH 3.4 Map17562.7UniSTS
Cytogenetic Map17q12.1UniSTS
RH144108  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21755,957,797 - 55,957,954 (-)MAPPERmRatBN7.2
Rnor_6.01760,911,882 - 60,912,038NCBIRnor6.0
Rnor_5.01762,688,335 - 62,688,491UniSTSRnor5.0
RGSC_v3.41764,565,803 - 64,565,959UniSTSRGSC3.4
Celera1757,272,064 - 57,272,220UniSTS
RH 3.4 Map17562.3UniSTS
Cytogenetic Map17q12.1UniSTS
AA850129  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.262,003,555 - 2,003,740 (-)MAPPERmRatBN7.2
Rnor_6.01760,886,537 - 60,886,721NCBIRnor6.0
Rnor_6.01760,884,759 - 60,884,947NCBIRnor6.0
Rnor_5.01762,662,651 - 62,662,836NCBIRnor5.0
Rnor_5.01762,661,484 - 62,661,673NCBIRnor5.0
RGSC_v3.41764,591,525 - 64,591,710UniSTSRGSC3.4
RGSC_v3.4616,599,303 - 16,599,487UniSTSRGSC3.4
Celera61,805,077 - 1,805,261UniSTS
RH 3.4 Map17572.2UniSTS
Cytogenetic Map17q12.1UniSTS
Cytogenetic Map18p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001270417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010058875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010058876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB574169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000058852   ⟹   ENSRNOP00000055641
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1755,923,123 - 55,981,660 (+)Ensembl
Rnor_6.0 Ensembl1760,888,017 - 60,946,426 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116963   ⟹   ENSRNOP00000082342
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1755,923,282 - 55,982,301 (+)Ensembl
RefSeq Acc Id: NM_001270417   ⟹   NP_001257346
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,111 - 60,676,640 (+)NCBI
mRatBN7.21755,923,123 - 55,981,660 (+)NCBI
Rnor_6.01760,887,606 - 60,946,630 (-)NCBI
Rnor_5.01762,663,721 - 62,723,083 (-)NCBI
Celera1757,238,053 - 57,291,859 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039095730   ⟹   XP_038951658
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,677,771 (+)NCBI
mRatBN7.21755,922,946 - 55,982,791 (+)NCBI
RefSeq Acc Id: XM_039095733   ⟹   XP_038951661
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,617,789 - 60,677,771 (+)NCBI
mRatBN7.21755,922,686 - 55,982,791 (+)NCBI
RefSeq Acc Id: XM_039095734   ⟹   XP_038951662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,458 - 60,677,771 (+)NCBI
mRatBN7.21755,923,474 - 55,984,286 (+)NCBI
RefSeq Acc Id: XM_039095738   ⟹   XP_038951666
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,677,771 (+)NCBI
mRatBN7.21755,922,947 - 55,982,791 (+)NCBI
RefSeq Acc Id: XM_063276462   ⟹   XP_063132532
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276463   ⟹   XP_063132533
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276464   ⟹   XP_063132534
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276465   ⟹   XP_063132535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276466   ⟹   XP_063132536
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,617,918 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276467   ⟹   XP_063132537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,181 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276468   ⟹   XP_063132538
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,617,702 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276469   ⟹   XP_063132539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,458 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276470   ⟹   XP_063132540
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,445 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276471   ⟹   XP_063132541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276472   ⟹   XP_063132542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,617,918 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276473   ⟹   XP_063132543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,445 - 60,677,771 (+)NCBI
RefSeq Acc Id: XR_010058875
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,666,509 (+)NCBI
RefSeq Acc Id: XR_010058876
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,666,509 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001257346   ⟸   NM_001270417
- UniProtKB: G3XEV5 (UniProtKB/TrEMBL),   F1LW69 (UniProtKB/TrEMBL),   A6KPM9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000055641   ⟸   ENSRNOT00000058852
RefSeq Acc Id: XP_038951661   ⟸   XM_039095733
- Peptide Label: isoform X7
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951658   ⟸   XM_039095730
- Peptide Label: isoform X3
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951666   ⟸   XM_039095738
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZWU8 (UniProtKB/TrEMBL),   A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951662   ⟸   XM_039095734
- Peptide Label: isoform X7
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000082342   ⟸   ENSRNOT00000116963
RefSeq Acc Id: XP_063132538   ⟸   XM_063276468
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063132536   ⟸   XM_063276466
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063132542   ⟸   XM_063276472
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063132537   ⟸   XM_063276467
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063132532   ⟸   XM_063276462
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063132533   ⟸   XM_063276463
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063132534   ⟸   XM_063276464
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063132535   ⟸   XM_063276465
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063132541   ⟸   XM_063276471
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063132540   ⟸   XM_063276470
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063132543   ⟸   XM_063276473
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063132539   ⟸   XM_063276469
- Peptide Label: isoform X7
Protein Domains
WW

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LW69-F1-model_v2 AlphaFold F1LW69 1-644 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562407 AgrOrtholog
BioCyc Gene G2FUF-8961 BioCyc
Ensembl Genes ENSRNOG00000018698 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000058852 ENTREZGENE
  ENSRNOT00000058852.5 UniProtKB/TrEMBL
  ENSRNOT00000116963.1 UniProtKB/TrEMBL
Gene3D-CATH 2.20.70.10 UniProtKB/TrEMBL
InterPro WAC UniProtKB/TrEMBL
  WW_dom_sf UniProtKB/TrEMBL
  WW_Rsp5_WWP UniProtKB/TrEMBL
KEGG Report rno:307029 UniProtKB/TrEMBL
NCBI Gene 307029 ENTREZGENE
PANTHER PTHR15911 UniProtKB/TrEMBL
  WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL UniProtKB/TrEMBL
Pfam PF00397 UniProtKB/TrEMBL
PhenoGen Wac PhenoGen
PROSITE WW_DOMAIN_1 UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018698 RatGTEx
SMART SM00456 UniProtKB/TrEMBL
Superfamily-SCOP WW_Rsp5_WWP UniProtKB/TrEMBL
UniProt A0A8I5ZWU8 ENTREZGENE, UniProtKB/TrEMBL
  A6KPM9 ENTREZGENE, UniProtKB/TrEMBL
  F1LW69 ENTREZGENE, UniProtKB/TrEMBL
  G3XEV5 ENTREZGENE
UniProt Secondary G3XEV5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-07-29 Wac  WW domain containing adaptor with coiled-coil  RGD1562407  similar to WAC  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1562407  similar to WAC   RGD1562407_predicted  similar to WAC (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1562407_predicted  similar to WAC (predicted)  LOC307029  similar to WAC  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC307029  similar to WAC      Symbol and Name status set to provisional 70820 PROVISIONAL