Gene: Cd74 (Cd74 molecule, major histocompatibility complex, class II invariant chain)  Rattus norvegicus

Symbol: Cd74
Name: Cd74 molecule, major histocompatibility complex, class II invariant chain
Description: ENCODES a protein that exhibits beta-amyloid binding (ortholog); cytokine binding (ortholog); cytokine receptor activity (ortholog); INVOLVED IN activation of MAPK activity; cell proliferation; antigen processing and presentation (ortholog); PARTICIPATES IN antigen processing and presentation pathway; Mycobacterium tuberculosis infection pathway; FOUND IN cell surface (ortholog); endoplasmic reticulum (ortholog); external side of plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-nitrofluorene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD74 antigen (invariant polpypeptide of major histocompatibility class II antigen-associated); CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); H-2 class II histocompatibility antigen gamma chain; ia antigen-associated invariant chain; ii; INVG34; MHC class II-associated invariant chain
Orthologs: Homo sapiens : CD74 (CD74 molecule, major histocompatibility complex, class II invariant chain)  HGNC
Mus musculus : Cd74 (CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated))  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map18q12.1 NCBI
RGSC Genome Assembly v5.01855,305,873 - 55,315,246+NCBI
RGSC Genome Assembly v3.41856,756,511 - 56,765,711+NCBI
Rat Celera Assembly1852,411,586 - 52,420,786+NCBI
Genome Assembly 3.11856,828,786 - 56,837,940+NCBI
RH 3.418525.0 RGD
Model

Launch Genome Browser (GBrowse)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Cd74
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 2313
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE