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Ontology Browser
Term:
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:0006977)
Annotations: Rat: (15) Mouse: (15) Human: (23) Chinchilla: (13) Bonobo: (16) Dog: (15) Squirrel: (14) Pig: (16) Naked Mole-rat: (13) Green Monkey: (14)
Parent Terms Term With Siblings Child Terms
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle.
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +   
negative regulation of DNA damage response, signal transduction by p53 class mediator +   
positive regulation of DNA damage response, signal transduction by p53 class mediator +   
regulation of DNA damage response, signal transduction by p53 class mediator +   

Synonyms
Exact Synonyms: positive regulation of cell cycle arrest by p53-mediated DNA damage response
Definition Sources: GOC:go_curators

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