Gene: Casp2 (caspase 2) Rattus norvegicus
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Symbol: Casp2
Name: caspase 2
Description: ENCODES a protein that exhibits cysteine-type endopeptidase activity (ortholog); cysteine-type endopeptidase activity involved in apoptotic process (ortholog); identical protein binding (ortholog); INVOLVED IN aging; apoptotic process; brain development; ASSOCIATED WITH basilar artery occlusion; carotid artery occlusion; cerebral arteritis; FOUND IN membrane; mitochondrion; cytoplasm (ortholog); INTERACTS WITH (R)-noradrenaline; (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CASP-2; caspase-2; ICH-1 protease; protease ICH-1
Orthologs:
Homo sapiens (human) : CASP2 (caspase 2)  HGNC
Mus musculus (house mouse) : Casp2 (caspase 2)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Casp2 (caspase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CASP2 (caspase 2)
Canis lupus familiaris (dog) : CASP2 (caspase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casp2 (caspase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0471,652,358 - 71,670,228 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.04136,454,723 - 136,474,625 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4470,029,728 - 70,047,164 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1470,305,857 - 70,323,294 (+)NCBI
Celera466,080,364 - 66,098,003 (+)NCBI
Cytogenetic Map4q24NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Casp2
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RGD Object Information
RGD ID: 69274
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2017-05-30
Status: ACTIVE