Nek11 (NIMA-related kinase 11) - Rat Genome Database

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Gene: Nek11 (NIMA-related kinase 11) Rattus norvegicus
Analyze
Symbol: Nek11
Name: NIMA-related kinase 11
RGD ID: 1308801
Description: Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in mitotic intra-S DNA damage checkpoint signaling and regulation of mitotic cell cycle phase transition. Predicted to be located in nucleolus. Predicted to be active in nucleoplasm. Orthologous to human NEK11 (NIMA related kinase 11); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC102552009; LOC315978; NIMA (never in mitosis gene a)- related kinase 11; NIMA (never in mitosis gene a)-related expressed kinase 11; serine/threonine-protein kinase Nek11; uncharacterized LOC102552009
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88114,646,010 - 114,905,242 (-)NCBIGRCr8
mRatBN7.28105,767,230 - 106,026,676 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8105,770,548 - 106,026,676 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8111,502,903 - 111,655,228 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08109,702,149 - 109,854,479 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08107,544,834 - 107,697,183 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08113,703,406 - 113,937,097 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8113,787,128 - 113,937,097 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08113,089,579 - 113,322,634 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48110,335,934 - 110,498,633 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18110,250,393 - 110,517,800 (-)NCBI
Celera8105,209,724 - 105,359,404 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleolus  (ISO)
nucleoplasm  (IBA,ISO)
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12154088   PMID:15161910   PMID:19734889  


Genomics

Comparative Map Data
Nek11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88114,646,010 - 114,905,242 (-)NCBIGRCr8
mRatBN7.28105,767,230 - 106,026,676 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8105,770,548 - 106,026,676 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8111,502,903 - 111,655,228 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08109,702,149 - 109,854,479 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08107,544,834 - 107,697,183 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08113,703,406 - 113,937,097 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8113,787,128 - 113,937,097 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08113,089,579 - 113,322,634 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48110,335,934 - 110,498,633 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18110,250,393 - 110,517,800 (-)NCBI
Celera8105,209,724 - 105,359,404 (-)NCBICelera
Cytogenetic Map8q32NCBI
NEK11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383131,026,877 - 131,350,465 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3131,026,850 - 131,350,465 (+)EnsemblGRCh38hg38GRCh38
GRCh373130,745,721 - 131,069,309 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363132,228,417 - 132,551,993 (+)NCBINCBI36Build 36hg18NCBI36
Celera3129,170,940 - 129,494,974 (+)NCBICelera
Cytogenetic Map3q22.1NCBI
HuRef3128,129,828 - 128,453,929 (+)NCBIHuRef
CHM1_13130,709,218 - 131,032,898 (+)NCBICHM1_1
T2T-CHM13v2.03133,770,580 - 134,094,242 (+)NCBIT2T-CHM13v2.0
Nek11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399105,039,355 - 105,272,723 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9105,039,355 - 105,272,723 (-)EnsemblGRCm39 Ensembl
GRCm389105,162,156 - 105,395,524 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9105,162,156 - 105,395,524 (-)EnsemblGRCm38mm10GRCm38
MGSCv379105,064,797 - 105,297,617 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369105,020,567 - 105,253,343 (-)NCBIMGSCv36mm8
Celera9104,752,212 - 104,992,782 (-)NCBICelera
Cytogenetic Map9F1NCBI
cM Map956.61NCBI
Nek11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555017,108,526 - 7,374,984 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555017,107,858 - 7,375,079 (-)NCBIChiLan1.0ChiLan1.0
NEK11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22128,983,467 - 129,311,793 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13128,988,218 - 129,313,179 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03128,111,202 - 128,434,781 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13135,433,828 - 135,757,221 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3135,433,828 - 135,757,221 (+)Ensemblpanpan1.1panPan2
NEK11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12328,244,116 - 28,496,595 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2328,247,451 - 28,442,816 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2328,216,697 - 28,471,321 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02328,751,145 - 29,004,266 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2328,751,332 - 28,994,086 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12328,447,449 - 28,700,030 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02328,506,210 - 28,759,470 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02328,755,881 - 29,011,340 (+)NCBIUU_Cfam_GSD_1.0
Nek11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560267,723,842 - 68,025,418 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365294,487,656 - 4,785,912 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365294,484,397 - 4,785,902 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NEK11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl131,145,284 - 1,435,652 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1131,145,225 - 1,435,690 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213983,600 - 1,092,961 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NEK11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11558,884,879 - 59,178,575 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1558,884,771 - 59,175,470 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604131,900,506 - 32,196,526 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nek11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247307,011,227 - 7,346,903 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247307,010,314 - 7,343,072 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nek11
2138 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:270
Count of miRNA genes:191
Interacting mature miRNAs:209
Transcripts:ENSRNOT00000046816
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat
631217Activ1Activity QTL 115.9voluntary movement trait (VT:0003491)number of photobeam interruptions in an experimental apparatus (CMO:0001517)8102370617108923645Rat

Markers in Region
D8Got330  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28105,915,667 - 105,915,753 (+)MAPPERmRatBN7.2
Rnor_6.08113,847,881 - 113,847,966NCBIRnor6.0
Rnor_5.08113,233,418 - 113,233,503UniSTSRnor5.0
RGSC_v3.48110,397,348 - 110,397,433UniSTSRGSC3.4
Celera8105,271,640 - 105,271,726UniSTS
Cytogenetic Map8q32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8 7
Low 3 28 55 39 18 39 2 2 66 35 34 11 2
Below cutoff 15 2 2 1 2 6 8 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001413824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000046816   ⟹   ENSRNOP00000047201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8105,770,548 - 106,026,676 (-)Ensembl
Rnor_6.0 Ensembl8113,787,128 - 113,937,097 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000084073
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl8114,176,210 - 114,178,966 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107138   ⟹   ENSRNOP00000093100
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8105,770,548 - 106,026,676 (-)Ensembl
RefSeq Acc Id: NM_001413824   ⟹   NP_001400753
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,646,010 - 114,905,162 (-)NCBI
mRatBN7.28105,767,230 - 106,026,383 (-)NCBI
RefSeq Acc Id: XM_008766530   ⟹   XP_008764752
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,648,988 - 114,903,036 (-)NCBI
mRatBN7.28105,767,230 - 106,026,518 (-)NCBI
Rnor_6.08113,703,406 - 113,936,814 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595681   ⟹   XP_017451170
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,648,988 - 114,903,036 (-)NCBI
mRatBN7.28105,767,230 - 106,026,518 (-)NCBI
Rnor_6.08113,703,406 - 113,936,814 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595686   ⟹   XP_017451175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,648,988 - 114,902,874 (-)NCBI
mRatBN7.28105,767,230 - 106,024,083 (-)NCBI
Rnor_6.08113,703,406 - 113,904,120 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595687   ⟹   XP_017451176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,648,988 - 114,905,242 (-)NCBI
mRatBN7.28105,767,230 - 106,026,518 (-)NCBI
Rnor_6.08113,703,406 - 113,936,807 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039081561   ⟹   XP_038937489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,660,695 - 114,903,036 (-)NCBI
mRatBN7.28105,781,903 - 106,026,518 (-)NCBI
RefSeq Acc Id: XM_039081562   ⟹   XP_038937490
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,648,988 - 114,905,207 (-)NCBI
mRatBN7.28105,767,230 - 106,026,518 (-)NCBI
RefSeq Acc Id: XM_039081565   ⟹   XP_038937493
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,648,988 - 114,799,867 (-)NCBI
mRatBN7.28105,767,230 - 105,916,365 (-)NCBI
RefSeq Acc Id: XM_039081566   ⟹   XP_038937494
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,785,905 - 114,903,036 (-)NCBI
mRatBN7.28105,904,794 - 106,026,676 (-)NCBI
RefSeq Acc Id: XM_039081567   ⟹   XP_038937495
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,785,905 - 114,903,036 (-)NCBI
mRatBN7.28105,904,792 - 106,026,518 (-)NCBI
RefSeq Acc Id: XM_063265609   ⟹   XP_063121679
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,648,988 - 114,903,036 (-)NCBI
RefSeq Acc Id: XM_063265610   ⟹   XP_063121680
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,648,988 - 114,903,036 (-)NCBI
RefSeq Acc Id: XM_063265612   ⟹   XP_063121682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,706,173 - 114,903,036 (-)NCBI
RefSeq Acc Id: XM_063265613   ⟹   XP_063121683
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,648,988 - 114,902,862 (-)NCBI
RefSeq Acc Id: XM_063265614   ⟹   XP_063121684
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,648,988 - 114,902,868 (-)NCBI
RefSeq Acc Id: XM_063265615   ⟹   XP_063121685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,777,559 - 114,903,036 (-)NCBI
RefSeq Acc Id: XM_063265616   ⟹   XP_063121686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,648,988 - 114,903,036 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008764752   ⟸   XM_008766530
- Peptide Label: isoform X14
- UniProtKB: D4A3H8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451170   ⟸   XM_017595681
- Peptide Label: isoform X2
- UniProtKB: D4A3H8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451176   ⟸   XM_017595687
- Peptide Label: isoform X4
- UniProtKB: D4A3H8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451175   ⟸   XM_017595686
- Peptide Label: isoform X4
- UniProtKB: D4A3H8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000047201   ⟸   ENSRNOT00000046816
RefSeq Acc Id: XP_038937490   ⟸   XM_039081562
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038937493   ⟸   XM_039081565
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038937489   ⟸   XM_039081561
- Peptide Label: isoform X5
- UniProtKB: A6I2N1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937495   ⟸   XM_039081567
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038937494   ⟸   XM_039081566
- Peptide Label: isoform X11
RefSeq Acc Id: ENSRNOP00000093100   ⟸   ENSRNOT00000107138
RefSeq Acc Id: NP_001400753   ⟸   NM_001413824
- UniProtKB: A0A8I6AI15 (UniProtKB/TrEMBL),   D4A3H8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121680   ⟸   XM_063265610
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063121679   ⟸   XM_063265609
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063121686   ⟸   XM_063265616
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063121684   ⟸   XM_063265614
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063121683   ⟸   XM_063265613
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063121682   ⟸   XM_063265612
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063121685   ⟸   XM_063265615
- Peptide Label: isoform X10
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3H8-F1-model_v2 AlphaFold D4A3H8 1-507 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308801 AgrOrtholog
BioCyc Gene G2FUF-29277 BioCyc
Ensembl Genes ENSRNOG00000042432 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000055782 Ensembl
Ensembl Transcript ENSRNOT00000046816.4 UniProtKB/TrEMBL
  ENSRNOT00000107138 ENTREZGENE
  ENSRNOT00000107138.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Ser/Thr_prot_kinase_AS UniProtKB/TrEMBL
KEGG Report rno:315978 UniProtKB/TrEMBL
NCBI Gene 315978 ENTREZGENE
PANTHER CAMK FAMILY PROTEIN KINASE UniProtKB/TrEMBL
  NIMA-RELATED KINASE 11 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Nek11 PhenoGen
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000042432 RatGTEx
  ENSRNOG00000055782 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0A8I6AI15 ENTREZGENE, UniProtKB/TrEMBL
  A6I2N1 ENTREZGENE, UniProtKB/TrEMBL
  D4A3H8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Nek11  NIMA-related kinase 11  LOC102552009  uncharacterized LOC102552009  Data merged from RGD:7623679 737654 PROVISIONAL
2013-12-18 LOC102552009  uncharacterized LOC102552009      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-11-21 Nek11  NIMA-related kinase 11  Nek11  NIMA (never in mitosis gene a)- related kinase 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Nek11  NIMA (never in mitosis gene a)- related kinase 11  Nek11  NIMA (never in mitosis gene a)-related expressed kinase 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Nek11  NIMA (never in mitosis gene a)-related expressed kinase 11  Nek11_predicted  NIMA (never in mitosis gene a)- related kinase 11 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Nek11_predicted  NIMA (never in mitosis gene a)- related kinase 11 (predicted)      Symbol and Name status set to approved 70820 APPROVED