Gene: Kmt5a (lysine methyltransferase 5A) Rattus norvegicus
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Symbol: Kmt5a
Name: lysine methyltransferase 5A
Description: ENCODES a protein that exhibits histone-lysine N-methyltransferase activity (ortholog); p53 binding (ortholog); protein-lysine N-methyltransferase activity (ortholog); INVOLVED IN negative regulation of transcription from RNA polymerase II promoter (ortholog); negative regulation of transcription, DNA-templated (ortholog); peptidyl-lysine monomethylation (ortholog); PARTICIPATES IN methionine cycle/metabolic pathway; lysine degradation pathway; ASSOCIATED WITH prostate cancer (ortholog); prostate cancer (ortholog); Prostatic Neoplasms (ortholog); FOUND IN cytosol (ortholog); nucleus (ortholog); INTERACTS WITH diuron; ketamine; 2,3,7,8-tetrachlorodibenzodioxine (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: histone methyltransferase Pr-set7/Set8; histone-lysine N-methyltransferase SETD8; LOC689820; lysine (K)-specific methyltransferase 5A; N-lysine methyltransferase KMT5A; N-lysine methyltransferase SETD8; Pr-set7; RGD1305893; SET domain containing (lysine methyltransferase) 8; SET domain-containing 8; Setd8; similar to SET domain-containing protein
Orthologs:
Homo sapiens (human) : KMT5A (lysine methyltransferase 5A)  HGNC  AGR
Mus musculus (house mouse) : Kmt5a (lysine methyltransferase 5A)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Kmt5a (lysine methyltransferase 5A)
Pan paniscus (bonobo/pygmy chimpanzee) : KMT5A (lysine methyltransferase 5A)
Canis lupus familiaris (dog) : KMT5A (lysine methyltransferase 5A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kmt5a (lysine methyltransferase 5A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01237,558,150 - 37,581,183 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01239,428,363 - 39,452,079 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41233,254,018 - 33,270,657 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1233,829,691 - 33,843,975 (-)NCBICelera
Cytogenetic Map12q15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Kmt5a
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1587560
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE