Gene: Setd8 (SET domain containing (lysine methyltransferase) 8) Rattus norvegicus
Symbol: Setd8
Name: SET domain containing (lysine methyltransferase) 8
Description: ENCODES a protein that exhibits histone-lysine N-methyltransferase activity (ortholog); p53 binding (ortholog); protein-lysine N-methyltransferase activity (ortholog); INVOLVED IN histone lysine methylation (ortholog); negative regulation of transcription from RNA polymerase II promoter (ortholog); negative regulation of transcription, DNA-templated (ortholog); PARTICIPATES IN methionine cycle/metabolic pathway; lysine degradation pathway; ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN nucleolus (ortholog); nucleus (ortholog); INTERACTS WITH diuron; ketamine; 2,3,7,8-tetrachlorodibenzodioxine (ortholog)
Type: protein-coding
Also known as: histone methyltransferase Pr-set7/Set8; histone-lysine N-methyltransferase SETD8; LOC689820; N-lysine methyltransferase SETD8; Pr-set7; RGD1305893; SET domain-containing 8; similar to SET domain-containing protein
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01237,558,150 - 37,581,183-NCBI
Rat Cytogenetic Map12q15 NCBI
RGSC Genome Assembly v5.01239,428,363 - 39,452,079-NCBI
RGSC Genome Assembly v3.41233,254,018 - 33,270,657-NCBI
Rat Celera Assembly1233,829,691 - 33,843,975-NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Setd8
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1587560
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2015-05-12
Status: ACTIVE