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280 records found for search term Pdc
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
3277PdcphosducinINVOLVED IN regulation of G protein-coupled receptor signaling pathway (inferred); visual perception (inferred); FOUND IN photoreceptor outer segment (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; ammonium chloride136484736664921865Rat22symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
737392PDCphosducinThis gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting1186443566186461114Human24symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
737393PdcphosducinPredicted to be involved in regulation of G protein-coupled receptor signaling pathway and visual perception. Located in photoreceptor outer segment. Is expressed in several structures, including central nervous system; foot; skeleton; and spinal nerve plexus. Orthologous to human PDC1150195168150209657Mouse44symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8811326PdcphosducinFOUND IN photoreceptor outer segment (ortholog)NW_0049554062485779124873057Chinchilla4symbolgene, protein-coding, MODEL [RefSeq]
12042182PDCphosducinINVOLVED IN regulation of G protein-coupled receptor signaling pathway (inferred); visual perception (inferred); FOUND IN cytosol (inferred); nucleus (inferred); photoreceptor inner segment (inferred)1161969161161976816Bonobo11symbolgene, protein-coding, MODEL [RefSeq]
12282587PDCphosducinINVOLVED IN regulation of G protein-coupled receptor signaling pathway (inferred); visual perception (inferred); FOUND IN cytosol (inferred); nucleus (inferred); photoreceptor inner segment (inferred)71949878519514225Dog11symbol , old_gene_namegene, protein-coding, VALIDATED [RefSeq]
12629194PdcphosducinINVOLVED IN regulation of G protein-coupled receptor signaling pathway (inferred); visual perception (inferred); FOUND IN cytosol (inferred); nucleus (inferred); photoreceptor inner segment (inferred)NW_00493648139748313995431Squirrel11symbolgene, protein-coding, MODEL [RefSeq]
14028104PDCphosducinINVOLVED IN regulation of G protein-coupled receptor signaling pathway (inferred); visual perception (inferred); FOUND IN cytosol (inferred); nucleus (inferred); photoreceptor inner segment (inferred)Pig11symbolgene, protein-coding, MODEL [RefSeq]
18569123PDCphosducinINVOLVED IN regulation of G protein-coupled receptor signaling pathway (inferred); visual perception (inferred); FOUND IN cytosol (inferred); nucleus (inferred); photoreceptor inner segment (inferred)Green Monkey11symbolgene, protein-coding, MODEL [RefSeq]
18921896PdcphosducinINVOLVED IN regulation of G protein-coupled receptor signaling pathway (inferred); visual perception (inferred); FOUND IN cytosol (inferred); nucleus (inferred); photoreceptor inner segment (inferred)Naked Mole-Rat10symbolgene, protein-coding, MODEL [RefSeq]
155244321pdcTropical Clawed Frogsymbolgene, null
626138967PdcphosducinFOUND IN photoreceptor outer segment (ortholog)Black Rat4symbolgene, protein-coding, MODEL [RefSeq]
155251232pdc.LAfrican Clawed Frogsymbolgene, null
155250224pdc.SAfrican Clawed Frogsymbolgene, null
14974272PDC-AS1PDC antisense RNA 11186435161186470291Humansymbol , COSMIC , name , ensembl_full_name , Human Proteome Mapgene, ncrna, VALIDATED [RefSeq]
5687695Pdcem2Mcwiphosducin; zinc finger nuclease induced mutant 2, Medical College of WisconsinThis allele was made by ZFN mutagenesis. The resulting mutation is a 14-bp deletion in exon 5 (del 489-502)Ratsymbol , old_gene_symbolgene, allele
5687712Pdcem3Mcwiphosducin; zinc finger nuclease induced mutant 3, Medical College of WisconsinThis allele was made by ZFN mutagenesis. The resulting mutation is a net 47-bp deletion in exon 5 (del 450-501, ins. Catcg)Ratsymbol , old_gene_symbolgene, allele
1323232Pdcd1programmed cell death 1Predicted to enable signaling receptor activity. Involved in negative regulation of immune response. Acts upstream of or within negative regulation of B cell apoptotic process; negative regulation of tolerance induction; and positive regulation of T cell apoptotic process. Located in external side o19396602793980278Mouse270symbol , PhenoGen , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1346850PNKDPNKD metallo-beta-lactamase domain containingThis gene is thought to play a role in the regulation of myofibrillogenesis. Mutations in this gene have been associated with the movement disorder paroxysmal non-kinesigenic dyskinesia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]2218270519218346793Human176old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
735274Dlatdihydrolipoamide S-acetyltransferaseEnables acetyltransferase activity. Involved in pyruvate catabolic process and pyruvate decarboxylation to acetyl-CoA. Located in mitochondrion and myelin sheath. Is active in mitochondrial matrix. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous 95054593350571080Mouse228old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
619859Dlatdihydrolipoamide S-acetyltransferaseENCODES a protein that exhibits dihydrolipoyllysine-residue acetyltransferase activity; acetyltransferase activity (ortholog); identical protein binding (ortholog); INVOLVED IN pyruvate decarboxylation to acetyl-CoA; pyruvate catabolic process (ortholog); tricarboxylic acid cycle (ortholog); PARTICI85987553759900947Rat215old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
735273DLATdihydrolipoamide S-acetyltransferaseThis gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of t11112025408112064404Human305description , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
14379827PDC2Yeastsymbolgene, null
621135Pdclphosducin likeENCODES a protein that exhibits protein-containing complex binding; INVOLVED IN negative regulation of protein refolding; protein folding; heterotrimeric G-protein complex assembly (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 3H-1,2-dithiole-3-thione; ammonium chloride; bisphenol A34151995341529545Rat66symbol , PhenoGen , old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
735514PDCLphosducin likePhosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling b9122818097122828588Human75symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
735515Pdclphosducin-likeInvolved in positive regulation of smoothened signaling pathway. Acts upstream of or within heterotrimeric G-protein complex assembly and visual perception. Predicted to be located in cilium. Predicted to be active in cytoplasm. Orthologous to human PDCL (phosdu23724008637249832Mouse84symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
9047238Pdclphosducin likeENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN heterotrimeric G-protein complex assembly (ortholog); negative regulation of protein refolding (ortholog); positive regulation of smoothened signaling pathway (ortholog); FOUND IN cytoplasm (ortholog)NW_00495541951234905132092Chinchilla14symbolgene, protein-coding, MODEL [RefSeq]
11667982PDCLphosducin likeENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN heterotrimeric G-protein complex assembly (ortholog); negative regulation of protein refolding (ortholog); protein folding (ortholog); FOUND IN cilium (inferred); cytoplasm (inferred)99394961393959913Bonobo20symbolgene, protein-coding, MODEL [RefSeq]
12320890PDCLphosducin likeENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN heterotrimeric G-protein complex assembly (ortholog); negative regulation of protein refolding (ortholog); protein folding (ortholog); FOUND IN cilium (inferred); cytoplasm (inferred)95994598859955295Dog20symbolgene, protein-coding, MODEL [RefSeq]
12590931Pdclphosducin likeENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN heterotrimeric G-protein complex assembly (ortholog); negative regulation of protein refolding (ortholog); protein folding (ortholog); FOUND IN cilium (inferred); cytoplasm (inferred)NW_0049364871130907311323529Squirrel20symbolgene, protein-coding, MODEL [RefSeq]
14006020PDCLphosducin likeENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN heterotrimeric G-protein complex assembly (ortholog); negative regulation of protein refolding (ortholog); positive regulation of smoothened signaling pathway (ortholog); FOUND IN cilium (inferred); cytoplasm Pig20symbolgene, protein-coding, MODEL [RefSeq]
18769026PDCLphosducin likeENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN heterotrimeric G-protein complex assembly (ortholog); negative regulation of protein refolding (ortholog); protein folding (ortholog); FOUND IN cilium (inferred); cytoplasm (inferred)Green Monkey20symbolgene, protein-coding, MODEL [RefSeq]
18932150Pdclphosducin likeENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN heterotrimeric G-protein complex assembly (ortholog); negative regulation of protein refolding (ortholog); positive regulation of smoothened signaling pathway (ortholog); FOUND IN cilium (inferred); cytoplasm Naked Mole-Rat19symbolgene, protein-coding, MODEL [RefSeq]
155254416pdclTropical Clawed Frogsymbolgene, null
1311658Pdcd1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of immune response (ortholog); negative regulation of T cell activation (ortholog); PARTI9101866124101879278Rat178symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1323231PDCD1programmed cell death 1Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiatio2241849884241858894Human256symbol , COSMIC , description , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
8979025Pdcd1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of immune response (ortholog); negative regulation of T cell activation (ortholog); ASSOCNW_0049555424929057747Chinchilla109symbolgene, protein-coding, MODEL [RefSeq]
12157317PDCD1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of T cell activation (ortholog); negative regulation of T cell mediated immune response t255160655951618903Dog112symbolgene, protein-coding, PROVISIONAL [RefSeq]
12508258Pdcd1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of tolerance induction (ortholog); positive regulation of apoptotic process (ortholog); ANW_004936745152571163712Squirrel114symbolgene, protein-coding, MODEL [RefSeq]
13906369PDCD1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of tolerance induction (ortholog); positive regulation of apoptotic process (ortholog); APig113symbolgene, protein-coding, PROVISIONAL [RefSeq]
18493263PDCD1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of tolerance induction (ortholog); positive regulation of apoptotic process (ortholog); AGreen Monkey120symbolgene, protein-coding, MODEL [RefSeq]
18932577Pdcd1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of T cell activation (ortholog); negative regulation of T cell mediated immune response tNaked Mole-Rat112symbolgene, protein-coding, MODEL [RefSeq]
32728868PDCD1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of immune response (ortholog); negative regulation of T cell activation (ortholog); ASSOC12130849353130858776Bonobo109symbolgene, protein-coding, MODEL [RefSeq]
287996291pdcd1Tropical Clawed Frogsymbolgene, null
625834270Pdcd1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of immune response (ortholog); negative regulation of T cell activation (ortholog); ASSOCBlack Rat109symbolgene, protein-coding, MODEL [RefSeq]
61887Pdcd2programmed cell death 2ENCODES a protein that exhibits enzyme binding (ortholog); protein carrier chaperone (ortholog); INVOLVED IN programmed cell death; regulation of hematopoietic progenitor cell differentiation (ortholog); ribosomal small subunit biogenesis (ortholog); FOUND IN cytosol (ortholog); nucleolus (ortholog)16515803465163524Rat99symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
62180Pdcd2programmed cell death 2Predicted to enable enzyme binding activity. Predicted to be involved in positive regulation of apoptotic process; positive regulation of hematopoietic stem cell proliferation; and regulation of hematopoietic progenitor cell differentiation. Predicted to be located in cytoplasm. Predicted to be acti171573947215747560Mouse114symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
733734PDCD2programmed cell death 2This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on t6170575295170584637Human102symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
8877139Pdcd2programmed cell death 2ENCODES a protein that exhibits enzyme binding (ortholog); protein carrier chaperone (ortholog); INVOLVED IN programmed cell death (ortholog); regulation of hematopoietic progenitor cell differentiation (ortholog); ribosomal small subunit biogenesis (ortholog); FOUND IN cytosol (ortholog); nucleolusNW_00495541132566123262685Chinchilla11symbolgene, protein-coding, MODEL [RefSeq]
12041783PDCD2programmed cell death 2ENCODES a protein that exhibits DNA binding (inferred); enzyme binding (inferred); metal ion binding (inferred); INVOLVED IN programmed cell death (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleolus (inferred)6168735480168745897Bonobo19symbolgene, protein-coding, MODEL [RefSeq]
12115967PDCD2programmed cell death 2ENCODES a protein that exhibits enzyme binding (ortholog); protein carrier chaperone (ortholog); INVOLVED IN programmed cell death (ortholog); regulation of hematopoietic progenitor cell differentiation (ortholog); ribosomal small subunit biogenesis (ortholog); FOUND IN cytosol (ortholog); nucleolus127248263572488678Dog19symbolgene, protein-coding, MODEL [RefSeq]
12555670Pdcd2programmed cell death 2ENCODES a protein that exhibits DNA binding (inferred); enzyme binding (inferred); metal ion binding (inferred); INVOLVED IN programmed cell death (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleolus (inferred)NW_0049370983923746181Squirrel19symbolgene, protein-coding, MODEL [RefSeq]
13884447PDCD2programmed cell death 2ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN apoptotic process (inferred); programmed cell death (inferred); FOUND IN cytoplasm (inferred); nucleus (inferred)Pig7symbolgene, protein-coding, PROVISIONAL [RefSeq]
18451146PDCD2programmed cell death 2ENCODES a protein that exhibits DNA binding (inferred); enzyme binding (inferred); metal ion binding (inferred); INVOLVED IN programmed cell death (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleolus (inferred)Green Monkey19symbolgene, protein-coding, MODEL [RefSeq]
18922489Pdcd2programmed cell death 2ENCODES a protein that exhibits enzyme binding (ortholog); protein carrier chaperone (ortholog); INVOLVED IN programmed cell death (ortholog); regulation of hematopoietic progenitor cell differentiation (ortholog); ribosomal small subunit biogenesis (ortholog); FOUND IN cytosol (ortholog); nucleolusNaked Mole-Rat19symbolgene, protein-coding, MODEL [RefSeq]
155234102pdcd2Tropical Clawed Frogsymbolgene, null
625984356Pdcd2programmed cell death 2ENCODES a protein that exhibits enzyme binding (ortholog); protein carrier chaperone (ortholog); INVOLVED IN programmed cell death (ortholog); regulation of hematopoietic progenitor cell differentiation (ortholog); ribosomal small subunit biogenesis (ortholog); FOUND IN cytosol (ortholog); nucleolusBlack Rat11symbolgene, protein-coding, MODEL [RefSeq]
620816Pdcd4programmed cell death 4ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN epithelial to mesenchymal transition involved in cardiac fibroblast development; negative regulation of apoptotic process; positive regulation of smooth muscle cell apoptotic process; PARTICIPATES IN mTOR signaling pathway; ASSOCIAT1262912659262949581Rat304symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
732159PDCD4programmed cell death 4This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]10110871928110900006Human301symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
732160Pdcd4programmed cell death 4Predicted to enable RNA binding activity. Involved in cellular response to lipopolysaccharide; negative regulation of cytokine production involved in inflammatory response; and positive regulation of inflammatory response. Predicted to be located in cytoplasm. Predicted to be active in cytosol and n195388066253926024Mouse315symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8756869Pdcd4programmed cell death 4INVOLVED IN BMP signaling pathway (ortholog); cellular response to lipopolysaccharide (ortholog); epithelial to mesenchymal transition involved in cardiac fibroblast development (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Arterial Injury (ortholog); Lung Neoplasms (ortholog);NW_004955485530642553508Chinchilla41symbolgene, protein-coding, MODEL [RefSeq]
11962247PDCD4programmed cell death 4ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN epithelial to mesenchymal transition involved in cardiac fibroblast development (ortholog); negative regulation of apoptotic process (ortholog); positive regulation of smooth muscle cell apoptotic process (ortholog); PARTICIPATES IN10107465084107493285Bonobo46symbolgene, protein-coding, MODEL [RefSeq]
12272961PDCD4programmed cell death 4ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN epithelial to mesenchymal transition involved in cardiac fibroblast development (ortholog); negative regulation of apoptotic process (ortholog); positive regulation of smooth muscle cell apoptotic process (ortholog); PARTICIPATES IN282219827422227184Dog46symbolgene, protein-coding, MODEL [RefSeq]
12613974Pdcd4programmed cell death 4ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN epithelial to mesenchymal transition involved in cardiac fibroblast development (ortholog); negative regulation of apoptotic process (ortholog); positive regulation of smooth muscle cell apoptotic process (ortholog); PARTICIPATES INNW_00493648616841671705387Squirrel46symbolgene, protein-coding, MODEL [RefSeq]
14024960PDCD4programmed cell death 4ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN epithelial to mesenchymal transition involved in cardiac fibroblast development (ortholog); negative regulation of apoptotic process (ortholog); positive regulation of smooth muscle cell apoptotic process (ortholog); PARTICIPATES INPig48symbolgene, protein-coding, MODEL [RefSeq]
14388312Pdcd4Flysymbolgene, null
18794242PDCD4programmed cell death 4ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN epithelial to mesenchymal transition involved in cardiac fibroblast development (ortholog); negative regulation of apoptotic process (ortholog); positive regulation of smooth muscle cell apoptotic process (ortholog); PARTICIPATES INGreen Monkey46symbolgene, protein-coding, MODEL [RefSeq]
18919539Pdcd4programmed cell death 4ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN epithelial to mesenchymal transition involved in cardiac fibroblast development (ortholog); negative regulation of apoptotic process (ortholog); positive regulation of smooth muscle cell apoptotic process (ortholog); PARTICIPATES INNaked Mole-Rat46symbolgene, protein-coding, MODEL [RefSeq]
155258048pdcd4Tropical Clawed Frogsymbolgene, null
625858807Pdcd4programmed cell death 4INVOLVED IN BMP signaling pathway (ortholog); cellular response to lipopolysaccharide (ortholog); epithelial to mesenchymal transition involved in cardiac fibroblast development (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Arterial Injury (ortholog); Lung Neoplasms (ortholog);Black Rat41symbolgene, protein-coding, MODEL [RefSeq]
1310561Pdcd5programmed cell death 5ENCODES a protein that exhibits acetyltransferase activator activity (ortholog); beta-tubulin binding (ortholog); heparin binding (ortholog); INVOLVED IN cellular response to transforming growth factor beta stimulus (ortholog); negative regulation of protein folding (ortholog); positive regulation o19744275597448084Rat104symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1321536PDCD5programmed cell death 5This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by in193258119032587453Human108symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1321537Pdcd5programmed cell death 5Predicted to enable acetyltransferase activator activity; beta-tubulin binding activity; and heparin binding activity. Predicted to be involved in several processes, including cellular response to transforming growth factor beta stimulus; negative regulation of chaperone-mediated protein folding; an73534141035346907Mouse108symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8832094Pdcd5programmed cell death 5ENCODES a protein that exhibits acetyltransferase activator activity (ortholog); beta-tubulin binding (ortholog); heparin binding (ortholog); INVOLVED IN cellular response to transforming growth factor beta stimulus (ortholog); negative regulation of protein folding (ortholog); positive regulation oNW_00495546853651375372888Chinchilla12symbolgene, protein-coding, MODEL [RefSeq]
11693600PDCD5programmed cell death 5ENCODES a protein that exhibits acetyltransferase activator activity (ortholog); beta-tubulin binding (ortholog); heparin binding (ortholog); INVOLVED IN cellular response to transforming growth factor beta stimulus (ortholog); negative regulation of protein folding (ortholog); positive regulation o192950098329507277Bonobo15symbolgene, protein-coding, MODEL [RefSeq]
12126044PDCD5programmed cell death 5ENCODES a protein that exhibits acetyltransferase activator activity (ortholog); beta-tubulin binding (ortholog); heparin binding (ortholog); INVOLVED IN cellular response to transforming growth factor beta stimulus (ortholog); negative regulation of protein folding (ortholog); positive regulation o1119379427119384664Dog16symbolgene, protein-coding, MODEL [RefSeq]
12586445Pdcd5programmed cell death 5ENCODES a protein that exhibits acetyltransferase activator activity (inferred); beta-tubulin binding (inferred); DNA binding (inferred); INVOLVED IN apoptotic process (inferred); cellular response to transforming growth factor beta stimulus (inferred); negative regulation of protein folding (inferrNW_00493657031032233109399Squirrel16symbolgene, protein-coding, MODEL [RefSeq]
13916298PDCD5programmed cell death 5ENCODES a protein that exhibits acetyltransferase activator activity (inferred); beta-tubulin binding (inferred); DNA binding (inferred); INVOLVED IN apoptotic process (inferred); cellular response to transforming growth factor beta stimulus (inferred); negative regulation of protein folding (inferrPig16symbolgene, protein-coding, MODEL [RefSeq]
18697202PDCD5programmed cell death 5ENCODES a protein that exhibits acetyltransferase activator activity (inferred); beta-tubulin binding (inferred); DNA binding (inferred); INVOLVED IN apoptotic process (inferred); cellular response to transforming growth factor beta stimulus (inferred); negative regulation of protein folding (inferrGreen Monkey16symbolgene, protein-coding, MODEL [RefSeq]
18935360Pdcd5programmed cell death 5ENCODES a protein that exhibits acetyltransferase activator activity (ortholog); beta-tubulin binding (ortholog); heparin binding (ortholog); INVOLVED IN cellular response to transforming growth factor beta stimulus (ortholog); negative regulation of protein folding (ortholog); positive regulation oNaked Mole-Rat15symbolgene, protein-coding, MODEL [RefSeq]
155254355pdcd5Tropical Clawed Frogsymbolgene, null
626049090Pdcd5programmed cell death 5ENCODES a protein that exhibits acetyltransferase activator activity (ortholog); beta-tubulin binding (ortholog); heparin binding (ortholog); INVOLVED IN cellular response to transforming growth factor beta stimulus (ortholog); negative regulation of protein folding (ortholog); positive regulation oBlack Rat12symbolgene, protein-coding, MODEL [RefSeq]
1311239Pdcd6programmed cell death 6ENCODES a protein that exhibits calcium ion binding (ortholog); calcium-dependent protein binding (ortholog); identical protein binding (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to heat (ortholog); COPII vesicle coating (ortholog); FOUND IN COPII vesicle coat (ortholog)13079510530810771Rat203symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1322592PDCD6programmed cell death 6This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-ind5271646314974Human176symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1322593Pdcd6programmed cell death 6Enables calcium-dependent protein binding activity; metal ion binding activity; and protein homodimerization activity. Involved in response to calcium ion. Acts upstream of or within apoptotic process. Located in cytoplasm. Orthologous to human PDCD6 (programmed137445124074465445Mouse204symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8897309Pdcd6programmed cell death 6ENCODES a protein that exhibits calcium ion binding (ortholog); calcium-dependent protein binding (ortholog); identical protein binding (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to heat (ortholog); COPII vesicle coating (ortholog); FOUND IN COPII vesicle coat (ortholog)NW_0049555047537894654Chinchilla76symbolgene, protein-coding, MODEL [RefSeq]
12085609PDCD6programmed cell death 6ENCODES a protein that exhibits calcium ion binding (inferred); calcium-dependent protein binding (inferred); identical protein binding (inferred); INVOLVED IN apoptotic process (ortholog); FOUND IN COPII vesicle coat (inferred); Cul3-RING ubiquitin ligase complex (inferred); cytoplasm (inferred)341190965711929850Dog77symbolgene, protein-coding, MODEL [RefSeq]
12625271Pdcd6programmed cell death 6ENCODES a protein that exhibits calcium ion binding (inferred); calcium-dependent protein binding (inferred); identical protein binding (inferred); INVOLVED IN apoptotic process (ortholog); FOUND IN COPII vesicle coat (inferred); Cul3-RING ubiquitin ligase complex (inferred); cytoplasm (inferred)NW_00493681511293671144020Squirrel77symbolgene, protein-coding, MODEL [RefSeq]
14165156PDCD6programmed cell death 6ENCODES a protein that exhibits identical protein binding (ortholog); magnesium ion binding (ortholog); protein dimerization activity (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to heat (ortholog); COPII vesicle coating (ortholog); FOUND IN COPII vesicle coat (ortholog); Pig72symbolgene, protein-coding, MODEL [RefSeq]
18427398PDCD6programmed cell death 6ENCODES a protein that exhibits calcium ion binding (inferred); calcium-dependent protein binding (inferred); identical protein binding (inferred); INVOLVED IN apoptotic process (ortholog); FOUND IN COPII vesicle coat (inferred); Cul3-RING ubiquitin ligase complex (inferred); cytoplasm (inferred)Green Monkey77symbolgene, protein-coding, MODEL [RefSeq]
18916574Pdcd6programmed cell death 6ENCODES a protein that exhibits identical protein binding (ortholog); magnesium ion binding (ortholog); protein dimerization activity (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to heat (ortholog); COPII vesicle coating (ortholog); FOUND IN COPII vesicle coat (ortholog); Naked Mole-Rat72symbolgene, protein-coding, MODEL [RefSeq]
155247553pdcd6Tropical Clawed Frogsymbolgene, null
402525704PDCD6programmed cell death 6ENCODES a protein that exhibits calcium ion binding (ortholog); calcium-dependent protein binding (ortholog); identical protein binding (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to heat (ortholog); COPII vesicle coating (ortholog); FOUND IN COPII vesicle coat (ortholog)Bonobo76symbolgene, protein-coding, MODEL [RefSeq]
625893184Pdcd6programmed cell death 6ENCODES a protein that exhibits calcium ion binding (ortholog); calcium-dependent protein binding (ortholog); identical protein binding (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to heat (ortholog); COPII vesicle coating (ortholog); FOUND IN COPII vesicle coat (ortholog)Black Rat76symbolgene, protein-coding, MODEL [RefSeq]
1308961Pdcd7programmed cell death 7INVOLVED IN positive regulation of apoptotic signaling pathway (ortholog); positive regulation of T cell apoptotic process (ortholog); response to glucocorticoid (ortholog); FOUND IN spliceosomal complex (ortholog); U12-type spliceosomal complex (ortholog); U2AF complex (ortholog); INTERACTS WITH 2,87475776874772495Rat63symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1319039PDCD7programmed cell death 7This gene encodes a 59 kDa protein that is associated with the U11 small nuclear ribonucleoprotein (snRNP), which is a component of the minor U12-type spliceosome responsible for catalyzing pre-mRNA splicing of U12-type introns. [provided by RefSeq, Dec 2010]156511737965133808Human68symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1319040Pdcd7programmed cell death 7Involved in response to glucocorticoid. Acts upstream of or within RNA splicing; positive regulation of T cell apoptotic process; and positive regulation of apoptotic signaling pathway. Part of U2AF complex and spliceosomal complex. Is expressed in several structures, including brain ventricular lay96525335065266925Mouse88symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
10228599Pdcd7programmed cell death 7INVOLVED IN positive regulation of apoptotic signaling pathway (ortholog); positive regulation of T cell apoptotic process (ortholog); response to glucocorticoid (ortholog); FOUND IN spliceosomal complex (ortholog); U11/U12 snRNP (ortholog); U12-type precatalytic spliceosome (ortholog)NW_0049554501029418410307234Chinchilla11symbolgene, protein-coding, MODEL [RefSeq]
11736838PDCD7programmed cell death 7INVOLVED IN positive regulation of apoptotic signaling pathway (ortholog); positive regulation of T cell apoptotic process (ortholog); response to glucocorticoid (ortholog); FOUND IN spliceosomal complex (ortholog); U11/U12 snRNP (ortholog); U12-type precatalytic spliceosome (ortholog)154405766744073812Bonobo11symbolgene, protein-coding, MODEL [RefSeq]
12342349PDCD7programmed cell death 7INVOLVED IN positive regulation of apoptotic signaling pathway (ortholog); positive regulation of T cell apoptotic process (ortholog); response to glucocorticoid (ortholog); FOUND IN U2AF complex (ortholog); INTERACTS WITH bisphenol A302949829029510991Dog8symbolgene, protein-coding, MODEL [RefSeq]
12649613Pdcd7programmed cell death 7INVOLVED IN positive regulation of apoptotic signaling pathway (ortholog); positive regulation of T cell apoptotic process (ortholog); response to glucocorticoid (ortholog); FOUND IN U2AF complex (ortholog)NW_0049364712543295625444036Squirrel7symbolgene, protein-coding, MODEL [RefSeq]
14218925PDCD7programmed cell death 7INVOLVED IN positive regulation of apoptotic signaling pathway (ortholog); positive regulation of T cell apoptotic process (ortholog); response to glucocorticoid (ortholog); FOUND IN U2AF complex (ortholog)Pig7symbolgene, protein-coding, MODEL [RefSeq]
18642596PDCD7programmed cell death 7INVOLVED IN positive regulation of apoptotic signaling pathway (ortholog); positive regulation of T cell apoptotic process (ortholog); response to glucocorticoid (ortholog); FOUND IN U2AF complex (ortholog)Green Monkey7symbolgene, protein-coding, MODEL [RefSeq]
18907190Pdcd7programmed cell death 7INVOLVED IN positive regulation of apoptotic signaling pathway (ortholog); positive regulation of T cell apoptotic process (ortholog); response to glucocorticoid (ortholog); FOUND IN spliceosomal complex (ortholog); U11/U12 snRNP (ortholog); U12-type precatalytic spliceosome (ortholog)Naked Mole-Rat10symbolgene, protein-coding, MODEL [RefSeq]
284590692pdcd7Tropical Clawed Frogsymbolgene, null
626007029Pdcd7programmed cell death 7INVOLVED IN positive regulation of apoptotic signaling pathway (ortholog); positive regulation of T cell apoptotic process (ortholog); response to glucocorticoid (ortholog); FOUND IN spliceosomal complex (ortholog); U11/U12 snRNP (ortholog); U12-type precatalytic spliceosome (ortholog)Black Rat11symbolgene, protein-coding, MODEL [RefSeq]
1344096PDCL2phosducin like 2This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G pro45555651955592245Human26symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1558552Pdcl2phosducin-like 2Involved in acrosome assembly. Acts upstream of or within sperm axoneme assembly. Located in endoplasmic reticulum. Orthologous to human PDCL2 (phosducin like 2). [provided by Alliance of Genome Resources, Jul 2025]57645996376479003Mouse40symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1559712Pdcl2phosducin-like 2INVOLVED IN acrosome assembly (ortholog); flagellated sperm motility (ortholog); sperm axoneme assembly (ortholog); ASSOCIATED WITH male infertility (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; Cuprizon; trichloroethene143222877632249467Rat23symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
8755395Pdcl2phosducin like 2INVOLVED IN acrosome assembly (ortholog); flagellated sperm motility (ortholog); sperm axoneme assembly (ortholog); ASSOCIATED WITH male infertility (ortholog); FOUND IN endoplasmic reticulum (ortholog)NW_0049554471536411615386071Chinchilla9symbolgene, protein-coding, MODEL [RefSeq]
12013400PDCL2phosducin like 2INVOLVED IN acrosome assembly (ortholog); flagellated sperm motility (ortholog); sperm axoneme assembly (ortholog); ASSOCIATED WITH male infertility (ortholog); FOUND IN endoplasmic reticulum (ortholog)46834361568381364Bonobo11symbolgene, protein-coding, MODEL [RefSeq]
12300007PDCL2phosducin like 2INVOLVED IN acrosome assembly (ortholog); flagellated sperm motility (ortholog); sperm axoneme assembly (ortholog); ASSOCIATED WITH male infertility (ortholog); FOUND IN endoplasmic reticulum (ortholog)134783216147861716Dog11symbolgene, protein-coding, MODEL [RefSeq]
12648615Pdcl2phosducin like 2INVOLVED IN acrosome assembly (ortholog); flagellated sperm motility (ortholog); sperm axoneme assembly (ortholog); ASSOCIATED WITH male infertility (ortholog); FOUND IN endoplasmic reticulum (ortholog)NW_0049364821790771317927007Squirrel11symbolgene, protein-coding, MODEL [RefSeq]
13985129PDCL2phosducin like 2INVOLVED IN acrosome assembly (ortholog); flagellated sperm motility (ortholog); sperm axoneme assembly (ortholog); ASSOCIATED WITH male infertility (ortholog); FOUND IN endoplasmic reticulum (ortholog)Pig11symbolgene, protein-coding, MODEL [RefSeq]
18714996PDCL2phosducin like 2INVOLVED IN acrosome assembly (ortholog); flagellated sperm motility (ortholog); sperm axoneme assembly (ortholog); ASSOCIATED WITH male infertility (ortholog); FOUND IN endoplasmic reticulum (ortholog)Green Monkey11symbolgene, protein-coding, MODEL [RefSeq]
18933996Pdcl2phosducin like 2INVOLVED IN acrosome assembly (ortholog); flagellated sperm motility (ortholog); sperm axoneme assembly (ortholog); ASSOCIATED WITH male infertility (ortholog); FOUND IN endoplasmic reticulum (ortholog)Naked Mole-Rat11symbolgene, protein-coding, MODEL [RefSeq]
625844203Pdcl2phosducin like 2INVOLVED IN acrosome assembly (ortholog); flagellated sperm motility (ortholog); sperm axoneme assembly (ortholog); ASSOCIATED WITH male infertility (ortholog); FOUND IN endoplasmic reticulum (ortholog)Black Rat9symbolgene, protein-coding, MODEL [RefSeq]
1309663Pdcl3phosducin-like 3ENCODES a protein that exhibits protein folding chaperone; vascular endothelial growth factor receptor 2 binding (ortholog); INVOLVED IN cellular response to heat; protein folding; actin cytoskeleton organization (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum (o94873008348738554Rat123symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1320124PDCL3phosducin like 3This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G pro2100562993100576739Human108symbol , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1320125Pdcl3phosducin-like 3Enables vascular endothelial growth factor receptor 2 binding activity. Involved in angiogenesis and positive regulation of gene expression. Located in cytoplasm. Part of protein-containing complex. Orthologous to human PDCL3 (phosducin like 3). [provided by All13902689539036317Mouse126symbol , PhenoGen , descriptiongene, protein-coding, PROVISIONAL [RefSeq]
9000933Pdcl3phosducin like 3ENCODES a protein that exhibits protein folding chaperone (ortholog); vascular endothelial growth factor receptor 2 binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); angiogenesis (ortholog); cellular response to heat (ortholog); FOUND IN cytoplasm (ortholog); cytosol (orthoNW_00495547065534506563814Chinchilla31symbolgene, protein-coding, MODEL [RefSeq]
12004461PDCL3phosducin like 3ENCODES a protein that exhibits protein folding chaperone (inferred); vascular endothelial growth factor receptor 2 binding (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); cellular response to heat (ortholog); negative regulation of protein folding (ortholog); FOUND IN cytosol (oBonobo28symbolgene, protein-coding, MODEL [RefSeq]
12432484PDCL3phosducin like 3INVOLVED IN actin cytoskeleton organization (ortholog); cellular response to heat (ortholog); negative regulation of protein folding (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog)104221412742223986Dog30symbolgene, protein-coding, MODEL [RefSeq]
12659768Pdcl3phosducin like 3ENCODES a protein that exhibits protein folding chaperone (inferred); vascular endothelial growth factor receptor 2 binding (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); cellular response to heat (ortholog); negative regulation of protein folding (ortholog); FOUND IN cytosol (oNW_004936661419113428032Squirrel28symbolgene, protein-coding, MODEL [RefSeq]
14201642PDCL3phosducin like 3ENCODES a protein that exhibits protein folding chaperone (inferred); vascular endothelial growth factor receptor 2 binding (inferred); INVOLVED IN cellular response to heat (ortholog); negative regulation of ubiquitin-dependent protein catabolic process (ortholog); positive regulation of angiogenesPig35symbolgene, protein-coding, MODEL [RefSeq]
18413682PDCL3phosducin like 3ENCODES a protein that exhibits protein folding chaperone (inferred); vascular endothelial growth factor receptor 2 binding (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); cellular response to heat (ortholog); negative regulation of protein folding (ortholog); FOUND IN cytosol (oGreen Monkey28symbolgene, protein-coding, MODEL [RefSeq]
18905603Pdcl3phosducin like 3ENCODES a protein that exhibits protein folding chaperone (inferred); vascular endothelial growth factor receptor 2 binding (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); cellular response to heat (ortholog); negative regulation of protein folding (ortholog); FOUND IN cytosol (oNaked Mole-Rat28symbolgene, protein-coding, MODEL [RefSeq]
155236824pdcl3Tropical Clawed Frogsymbolgene, null
625932758Pdcl3phosducin like 3ENCODES a protein that exhibits protein folding chaperone (ortholog); vascular endothelial growth factor receptor 2 binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); angiogenesis (ortholog); cellular response to heat (ortholog); FOUND IN cytoplasm (ortholog); cytosol (orthoBlack Rat31symbolgene, protein-coding, MODEL [RefSeq]
14386268pdcd-2Roundwormsymbolgene, null
14378387PDCD-5Flysymbolgene, null
1351056PDCD10programmed cell death 10This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, an3167683298167734892Human250symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1359329Pdcd10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN cellular response to anoxia; negative regulation of inflammatory response; positive regulation of mesenchymal cell apoptotic process; ASSOCIATED WITH Subarachnoid Hemorrhage; varicocele; arteriovenous malformat2162602516162644690Rat169symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1550654Pdcd10programmed cell death 10Predicted to enable protein homodimerization activity and protein kinase binding activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in Golgi membrane; cell periphery; and cytosol. Predicted to be part of FAR/SIN/STRIPAK complex. Is expressed37542379775464159Mouse237symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8990026Pdcd10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); establishment of Golgi localization (ortholog); ASSOCIATED WITH arteriovenous malformations of the brain (orthNW_0049554481686657716887215Chinchilla76symbolgene, protein-coding, MODEL [RefSeq]
11708405PDCD10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (inferred); protein kinase binding (inferred); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH ar3164703909164755085Bonobo82symbolgene, protein-coding, MODEL [RefSeq]
12209768PDCD10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (inferred); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH arteriovenous malformations of the br343251210932553524Dog82symbolgene, protein-coding, MODEL [RefSeq]
12662444Pdcd10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (inferred); protein kinase binding (inferred); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH arNW_00493659346506244693387Squirrel82symbolgene, protein-coding, MODEL [RefSeq]
13955217PDCD10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (inferred); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH arteriovenous malformations of the brPig82symbolgene, protein-coding, PROVISIONAL [RefSeq]
18751208PDCD10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (inferred); protein kinase binding (inferred); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH arGreen Monkey82symbolgene, protein-coding, MODEL [RefSeq]
18926511Pdcd10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); establishment of Golgi localization (ortholog); ASSOCIATED WITH arteriovenous malformations of the brain (orthNaked Mole-Rat82symbolgene, protein-coding, MODEL [RefSeq]
155257051pdcd10Tropical Clawed Frogsymbolgene, null
625928641Pdcd10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); establishment of Golgi localization (ortholog); ASSOCIATED WITH arteriovenous malformations of the brain (orthBlack Rat76symbolgene, protein-coding, MODEL [RefSeq]
1304933Pdcd11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (ortholog); INVOLVED IN RNA processing (inferred); rRNA processing (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (ortholog); nucleolus (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodi1255922198255963336Rat102symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1312660Pdcd11programmed cell death 11Predicted to enable NF-kappaB binding activity and RNA binding activity. Predicted to be involved in rRNA processing. Located in cytosol. Is expressed in several structures, including blastocyst; brain; early embryo; olfactory epithelium; and thymus primordium. Orthologous to human PDC194707918347119585Mouse99symbol , PhenoGen , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1354347PDCD11programmed cell death 11PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 [PubMed 14624448]; Sweet et al., 2008 [PubMed 17654514]).[supplie10103396626103446294Human100symbol , COSMIC , description , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
9019729Pdcd11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (ortholog); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (ortholog); nucleolus (ortholog); nucleus (ortholog)NW_00495548571107047152301Chinchilla6symbolgene, protein-coding, MODEL [RefSeq]
11885633PDCD11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN RNA processing (inferred); rRNA processing (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (inferred); nucleolus (inferred); nucleus (inferred)1099994509100043784Bonobo15symbolgene, protein-coding, MODEL [RefSeq]
12421525PDCD11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (inferred); nucleic acid binding (inferred); INVOLVED IN RNA processing (inferred); rRNA processing (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (inferred); nucleolus (inferred); nucleus (inferred)281576793615812285Dog15symbolgene, protein-coding, MODEL [RefSeq]
12534979Pdcd11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN RNA processing (inferred); rRNA processing (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (inferred); nucleolus (inferred); nucleus (inferred)NW_00493660026315202676315Squirrel15symbolgene, protein-coding, MODEL [RefSeq]
14131051PDCD11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (inferred); nucleic acid binding (inferred); INVOLVED IN RNA processing (inferred); rRNA processing (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (inferred); nucleolus (inferred); nucleus (inferred)Pig15symbolgene, protein-coding, MODEL [RefSeq]
18665441PDCD11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN RNA processing (inferred); rRNA processing (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (inferred); nucleolus (inferred); nucleus (inferred)Green Monkey15symbolgene, protein-coding, MODEL [RefSeq]
18910497Pdcd11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (ortholog); INVOLVED IN RNA processing (inferred); rRNA processing (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (ortholog)Naked Mole-Rat13symbolgene, protein-coding, MODEL [RefSeq]
155242245pdcd11Tropical Clawed Frogsymbolgene, null
625868617Pdcd11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (ortholog); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (ortholog); nucleolus (ortholog); nucleus (ortholog)Black Rat6symbolgene, protein-coding, MODEL [RefSeq]
1332227Pdcd2lprogrammed cell death 2-likePredicted to be involved in apoptotic process. Predicted to be located in cytoplasm. Orthologous to human PDCD2L (programmed cell death 2 like). [provided by Alliance of Genome Resources, Jul 2025]73388392233896154Mouse62symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1589941Pdcd2lprogrammed cell death 2-likeFOUND IN cytoplasm (inferred); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil19594747695959738Rat57symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1601844PDCD2Lprogrammed cell death 2 likePredicted to be involved in apoptotic process. Located in membrane. [provided by Alliance of Genome Resources, Jul 2025]193440439934426168Human62symbol , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
8779851Pdcd2lprogrammed cell death 2 likeNW_00495546840116444027481Chinchilla2symbolgene, protein-coding, MODEL [RefSeq]
11676658PDCD2Lprogrammed cell death 2 likeINVOLVED IN apoptotic process (inferred); FOUND IN cytoplasm (inferred)193135734331380858Bonobo4symbolgene, protein-coding, MODEL [RefSeq]
12336097PDCD2Lprogrammed cell death 2 likeFOUND IN cytoplasm (inferred)1117887800117918399Dog4symbolgene, protein-coding, MODEL [RefSeq]
12582931Pdcd2lprogrammed cell death 2 likeINVOLVED IN apoptotic process (inferred); FOUND IN cytoplasm (inferred)NW_00493657015576451579075Squirrel4symbolgene, protein-coding, MODEL [RefSeq]
13909092PDCD2Lprogrammed cell death 2 likeFOUND IN cytoplasm (inferred); INTERACTS WITH deoxynivalenolPig5symbolgene, protein-coding, MODEL [RefSeq]
18460961PDCD2Lprogrammed cell death 2 likeINVOLVED IN apoptotic process (inferred); FOUND IN cytoplasm (inferred)Green Monkey4symbolgene, protein-coding, MODEL [RefSeq]
18920017Pdcd2lprogrammed cell death 2 likeINVOLVED IN apoptotic process (inferred); FOUND IN cytoplasm (inferred)Naked Mole-Rat4symbolgene, protein-coding, MODEL [RefSeq]
155247207pdcd2lTropical Clawed Frogsymbolgene, null
626070578Pdcd2lprogrammed cell death 2 likeBlack Rat2symbolgene, protein-coding, MODEL [RefSeq]
155244946pdcl.SAfrican Clawed Frogsymbolgene, null
287996237pdcd1.LAfrican Clawed Frogsymbolgene, null
329329968pdcd1.SAfrican Clawed Frogsymbolgene, null
155234103pdcd2.SAfrican Clawed Frogsymbolgene, null
16555472PDCD2P1PDCD2 pseudogene 19113850836113851635Humansymbol , old_gene_name , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
617301281PDCD2P2PDCD2 pseudogene 2Humansymbol , GTEx , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
155250484pdcd4.LAfrican Clawed Frogsymbolgene, null
155251050pdcd4.SAfrican Clawed Frogsymbolgene, null
155244684pdcd5.LAfrican Clawed Frogsymbolgene, null
155251937pdcd5.SAfrican Clawed Frogsymbolgene, null
1564319Pdcd5l1programmed cell death 5 like 1ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN apoptotic process (inferred); INTERACTS WITH bisphenol A; Cuprizon; indole-3-methanol38405161184053009Rat9symbol , PhenoGengene, protein-coding, PREDICTED [RefSeq]
8549004PDCD5P1programmed cell death 5 pseudogene 1121941315219413588Humansymbol , COSMIC , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
8549094PDCD5P2programmed cell death 5 pseudogene 257628091676281401Humansymbol , COSMIC , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
155238264pdcd6.LAfrican Clawed Frogsymbolgene, null
626173589pdcd6.SAfrican Clawed Frogsymbolgene, null
626180141pdcd6.SAfrican Clawed Frogsymbolgene, null
68357Pdcd6ipprogrammed cell death 6 interacting proteinENCODES a protein that exhibits SH3 domain binding; calcium-dependent protein binding (ortholog); protein dimerization activity (ortholog); INVOLVED IN actomyosin contractile ring assembly (ortholog); bicellular tight junction assembly (ortholog); extracellular exosome biogenesis (ortholog); PARTICI8122469223122524993Rat181symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
68505PDCD6IPprogrammed cell death 6 interacting proteinThis gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the prod33379863033869703Human225symbol , old_gene_name , COSMIC , description , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
68506Pdcd6ipprogrammed cell death 6 interacting proteinEnables identical protein binding activity and protein dimerization activity. Involved in several processes, including actomyosin contractile ring assembly; bicellular tight junction assembly; and maintenance of epithelial cell apical/basal polarity. Located in actomyosin; cytosol; and extracellular9113480812113537457Mouse218symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8714882Pdcd6ipprogrammed cell death 6 interacting proteinENCODES a protein that exhibits calcium-dependent protein binding (ortholog); protein dimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN actomyosin contractile ring assembly (ortholog); bicellular tight junction assembly (ortholog); extracellular exosome biogNW_00495542110348431109637Chinchilla63symbolgene, protein-coding, MODEL [RefSeq]
11674421PDCD6IPprogrammed cell death 6 interacting proteinENCODES a protein that exhibits calcium-dependent protein binding (ortholog); protein dimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN actomyosin contractile ring assembly (ortholog); bicellular tight junction assembly (ortholog); extracellular exosome biog33371960333793301Bonobo71symbolgene, protein-coding, MODEL [RefSeq]
12073295PDCD6IPprogrammed cell death 6 interacting proteinENCODES a protein that exhibits calcium-dependent protein binding (ortholog); protein dimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN actomyosin contractile ring assembly (ortholog); bicellular tight junction assembly (ortholog); extracellular exosome biog2341122994199230Dog71symbolgene, protein-coding, MODEL [RefSeq]
12577114Pdcd6ipprogrammed cell death 6 interacting proteinENCODES a protein that exhibits protein dimerization activity (ortholog); SH3 domain binding (ortholog); INVOLVED IN actomyosin contractile ring assembly (ortholog); bicellular tight junction assembly (ortholog); extracellular exosome biogenesis (ortholog); ASSOCIATED WITH osteoarthritis (ortholog);NW_0049364732401094224086836Squirrel72symbolgene, protein-coding, MODEL [RefSeq]
14134841PDCD6IPprogrammed cell death 6 interacting proteinENCODES a protein that exhibits calcium-dependent protein binding (ortholog); protein dimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN actomyosin contractile ring assembly (ortholog); bicellular tight junction assembly (ortholog); extracellular exosome biogPig72symbolgene, protein-coding, MODEL [RefSeq]
18439248PDCD6IPprogrammed cell death 6 interacting proteinENCODES a protein that exhibits protein dimerization activity (ortholog); SH3 domain binding (ortholog); INVOLVED IN actomyosin contractile ring assembly (ortholog); bicellular tight junction assembly (ortholog); extracellular exosome biogenesis (ortholog); ASSOCIATED WITH osteoarthritis (ortholog);Green Monkey72symbolgene, protein-coding, MODEL [RefSeq]
18918788Pdcd6ipprogrammed cell death 6 interacting proteinENCODES a protein that exhibits calcium-dependent protein binding (ortholog); protein dimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN actomyosin contractile ring assembly (ortholog); bicellular tight junction assembly (ortholog); extracellular exosome biogNaked Mole-Rat71symbolgene, protein-coding, MODEL [RefSeq]
155238327pdcd6ipTropical Clawed Frogsymbolgene, null
625943497Pdcd6ipprogrammed cell death 6 interacting proteinENCODES a protein that exhibits calcium-dependent protein binding (ortholog); protein dimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN actomyosin contractile ring assembly (ortholog); bicellular tight junction assembly (ortholog); extracellular exosome biogBlack Rat63symbolgene, protein-coding, MODEL [RefSeq]
38613548PDCD6P1PDCD6 pseudogene 1515975571634005Humansymbol , old_gene_name , COSMIC , name , Human Proteome Mapgene, pseudo, VALIDATED [RefSeq]
288070221pdcd7.LAfrican Clawed Frogsymbolgene, null
8552525PDCL2P1PDCL2 pseudogene 1X2319831823198710Humansymbol , COSMIC , name , Human Proteome Mapgene, pseudo, VALIDATED [RefSeq]
10400832PDCL2P2PDCL2 pseudogene 2116516019465160382Humansymbol , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
155236823pdcl3.LAfrican Clawed Frogsymbolgene, null
155243264pdcl3.SAfrican Clawed Frogsymbolgene, null
1354070PDCL3P1PDCL3 pseudogene 186038720160388192Humansymbol , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
5684196PDCL3P2PDCL3 pseudogene 28101871595101872579Humansymbol , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
7174896PDCL3P3PDCL3 pseudogene 331787726617878196Humansymbol , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
7174794PDCL3P4PDCL3 pseudogene 4INTERACTS WITH 2-hydroxypropanoic acid; acrylamide; lipopolysaccharide3101712434101713416Human5symbol , COSMIC , name , Human Proteome Mapgene, pseudo, VALIDATED [RefSeq]
7174938PDCL3P5PDCL3 pseudogene 56150827625150828620Humansymbol , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
7174871PDCL3P6PDCL3 pseudogene 615217981552180694Humansymbol , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
7174981PDCL3P7PDCL3 pseudogene 7126627593366276649Humansymbol , COSMIC , name , Human Proteome Mapgene, pseudo, MODEL [RefSeq]
155253770pdcd10.LAfrican Clawed Frogsymbolgene, null
155243231pdcd10.SAfrican Clawed Frogsymbolgene, null
155233812pdcd11.LAfrican Clawed Frogsymbolgene, null
1306403Pdcd1lg2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN negative regulation of activated T cell proliferation (ortholog); negative regulation of interleukin-10 production (ortholog); negative regulation of T cell activation (ortholog); ASSOCIATED WITH Spinal Cord Injuries; a1236572497236637490Rat82symbol , old_gene_name , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1314998PDCD1LG2programmed cell death 1 ligand 2Involved in negative regulation of activated T cell proliferation; negative regulation of interleukin-10 production; and negative regulation of type II interferon production. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Biomarker of pulmonar955105315571282Human87symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1552436Pdcd1lg2programmed cell death 1 ligand 2Acts upstream of or within negative regulation of T cell proliferation and positive regulation of T cell proliferation. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system epithelium; 192938831929450327Mouse110symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8805014Pdcd1lg2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN negative regulation of activated T cell proliferation (ortholog); negative regulation of interleukin-10 production (ortholog); negative regulation of T cell activation (ortholog); ASSOCIATED WITH autoimmune hepatitis (oNW_00495543495400479559335Chinchilla21symbolgene, protein-coding, MODEL [RefSeq]
12012241PDCD1LG2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (inferred); INVOLVED IN negative regulation of T cell proliferation (ortholog); positive regulation of T cell proliferation (ortholog); ASSOCIATED WITH autoimmune hepatitis (ortholog); Coxsackievirus Infections (ortholog); cutaneous leishmania953130715391676Bonobo32symbolgene, protein-coding, MODEL [RefSeq]
12115593PDCD1LG2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (inferred); INVOLVED IN negative regulation of T cell proliferation (ortholog); positive regulation of T cell proliferation (ortholog); ASSOCIATED WITH autoimmune hepatitis (ortholog); Coxsackievirus Infections (ortholog); cutaneous leishmania19363167693698560Dog33symbolgene, protein-coding, MODEL [RefSeq]
12602259Pdcd1lg2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (inferred); INVOLVED IN negative regulation of T cell proliferation (ortholog); positive regulation of T cell proliferation (ortholog); ASSOCIATED WITH autoimmune hepatitis (ortholog); Coxsackievirus Infections (ortholog); cutaneous leishmaniaNW_004936539190583229936Squirrel29symbolgene, protein-coding, MODEL [RefSeq]
13859274PDCD1LG2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (inferred); INVOLVED IN negative regulation of T cell proliferation (ortholog); positive regulation of T cell proliferation (ortholog); ASSOCIATED WITH autoimmune hepatitis (ortholog); Coxsackievirus Infections (ortholog); cutaneous leishmaniaPig33symbolgene, protein-coding, PROVISIONAL [RefSeq]
18542162PDCD1LG2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (inferred); INVOLVED IN negative regulation of T cell proliferation (ortholog); positive regulation of T cell proliferation (ortholog); ASSOCIATED WITH autoimmune hepatitis (ortholog); Coxsackievirus Infections (ortholog); cutaneous leishmaniaGreen Monkey32symbolgene, protein-coding, MODEL [RefSeq]
18918713Pdcd1lg2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN negative regulation of activated T cell proliferation (ortholog); negative regulation of interleukin-10 production (ortholog); negative regulation of T cell activation (ortholog); ASSOCIATED WITH autoimmune hepatitis (oNaked Mole-Rat21symbolgene, protein-coding, MODEL [RefSeq]
285812707pdcd1lg2Tropical Clawed Frogsymbolgene, null
626064547Pdcd1lg2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN negative regulation of activated T cell proliferation (ortholog); negative regulation of interleukin-10 production (ortholog); negative regulation of T cell activation (ortholog); ASSOCIATED WITH autoimmune hepatitis (oBlack Rat21symbolgene, protein-coding, MODEL [RefSeq]
155238662pdcd2l.LAfrican Clawed Frogsymbolgene, null
2299652Pdcd5-psprogrammed cell death 5, pseudogenePredicted to enable acetyltransferase activator activity; beta-tubulin binding activity; and heparin binding activity. Predicted to be involved in several processes, including cellular response to transforming growth factor beta stimulus; negative regulation of chaperone-mediated protein folding; an1189009519189010044Mouse1symbol , PhenoGen , old_gene_symbolgene, pseudo, INFERRED [RefSeq]
38653307PDCD6-DTPDCD6 divergent transcript5269556271524Humansymbol , GTEx , COSMIC , name , Human Proteome Mapgene, ncrna, VALIDATED [RefSeq]
7241979PDCD4-AS1PDCD4 antisense RNA 1INTERACTS WITH 17beta-estradiol; aristolochic acid A; benzo[a]pyrene10110868890110870904Human18symbol , COSMIC , name , Human Proteome Mapgene, ncrna, PREDICTED [RefSeq]
1593001Pdcd6-ps1programmed cell death 6, pseudogene 1X104026911104027485Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
155238326pdcd6ip.LAfrican Clawed Frogsymbolgene, null
8549097PDCD6IPP1PDCD6IP pseudogene 1152272710422744699Humansymbol , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
8549005PDCD6IPP2PDCD6IP pseudogene 2152878983428856574Humansymbol , COSMIC , name , Human Proteome Mapgene, pseudo, PROVISIONAL [RefSeq]
11415410Pdcd7-ps1programmed cell death 7, pseudogene 1115092648450928851Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
1584015Pdcl1-ps1phosducin-like 1, pseudogene 134126357041331087Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
284378902pdcd1lg2.LAfrican Clawed Frogsymbolgene, null
287692237pdcd1lg2.SAfrican Clawed Frogsymbolgene, null
15091047PDCD6-AHRRPDCD6-AHRR readthrough (NMD candidate)Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Predicted to be located in ER to Golgi transport vesicle membrane. [provided by Alliance of Genome Resources, Jul 2025]5271646438285Human7symbol , COSMIC , name , Human Proteome Mapgene, ncrna, VALIDATED [RefSeq]
38603561PDCD6IP-DTPDCD6IP divergent transcript33379364433798519Humansymbol , COSMIC , name , Human Proteome Mapgene, ncrna, VALIDATED [RefSeq]
2320082Pdcd6ip-ps1programmed cell death 6 interacting protein, pseudogene115716590057166600Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
731381Aifm1apoptosis-inducing factor, mitochondrion-associated 1Enables several functions, including FAD binding activity; NAD(P)H oxidase H2O2-forming activity; and poly-ADP-D-ribose binding activity. Involved in several processes, including intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; positive regulation of necroptotic proX4756382147602440Mouse601old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
735964DECR22,4-dienoyl-CoA reductase 2Enables 2,4-dienoyl-CoA reductase (NADPH) activity and trans-2-enoyl-CoA reductase (NADPH) activity. Involved in unsaturated fatty acid biosynthetic process. Predicted to be located in cytosol and peroxisomal membrane. Predicted to be active in peroxisome. [provided by Alliance of Genome Resources, 16401885412482Human137old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1320180Mrps30mitochondrial ribosomal protein S30Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including brain; early conceptus; genitourinary system; liver; and peripheral nervous system ganglion. Orthologous to human MRPS313118516646118523788Mouse82old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
732449Nphs2nephrosis 2, podocinActs upstream of or within gene expression. Located in cytoplasmic side of plasma membrane. Is active in cell periphery. Colocalizes with slit diaphragm. Is expressed in liver; metanephros; and ureter. Used to study nephrotic syndrome. Human ortholog(s) of this gene implicated in nephrotic syndrome 1156138105156155605Mouse222old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
736986NPHS2NPHS2 stomatin family member, podocinThis gene encodes a protein that plays a role in the regulation of glomerular permeability. Mutations in this gene cause steroid-resistant nephrotic syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]1179550539179575948Human319old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
11042P2rx1purinergic receptor P2X, ligand-gated ion channel, 1Enables monoatomic cation channel activity and purinergic nucleotide receptor activity. Acts upstream of or within several processes, including platelet activation; regulation of monoatomic ion transport; and serotonin secretion by platelet. Located in external side of plasma membrane and postsynapt117288988272906026Mouse182old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
620817Aifm1apoptosis inducing factor, mitochondria associated 1ENCODES a protein that exhibits DNA binding (ortholog); FAD binding (ortholog); NAD(P)H oxidase H2O2-forming activity (ortholog); INVOLVED IN cellular response to aldosterone; cellular response to estradiol stimulus; cellular response to hydrogen peroxide; PARTICIPATES IN ceramide signaling pathway;X132528107132567237Rat516old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
731380AIFM1apoptosis inducing factor mitochondria associated 1This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentatX130129362130165841Human688old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
32729585LOC117975274programmed cell death protein 1-like12130940566130951059Bonoboold_gene_symbolgene, protein-coding, MODEL [RefSeq]
1320179MRPS30mitochondrial ribosomal protein S30Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryot54480894744815514Human82old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
8933177Ubap1lubiquitin associated protein 1 likeASSOCIATED WITH fundus dystrophy (ortholog)NW_0049554501031203210332917Chinchilla1old_gene_symbolgene, protein-coding, MODEL [RefSeq]
1320536AVENapoptosis and caspase activation inhibitorInvolved in negative regulation of apoptotic process. Located in membrane. [provided by Alliance of Genome Resources, Jul 2025]153385178134075325Human94old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1553554Cd274CD274 antigenThe protein encoded by this gene is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domai192933942829365495Mouse404old_gene_name , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1352883CSN2casein betaThis gene is a member of the beta casein family. There are two types of casein protein, beta (encoded by this gene) and kappa, both of which are secreted in human milk. Beta casein is the principal protein in human milk and the primary source of essential amino acids for a suckling infant. Beta and 46995525669965728Human72old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1322853A530064D06RikRIKEN cDNA A530064D06 geneINTERACTS WITH 17beta-estradiol (ortholog); benzo[a]pyrene (ortholog); Cuprizon (ortholog)174845906448474425Mouse17old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1605684CD274CD274 moleculeThis gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of954505425470554Human325old_gene_name , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1566211Cd274CD274 moleculeENCODES a protein that exhibits receptor ligand activity (ortholog); transcription coactivator activity (ortholog); INVOLVED IN positive regulation of cell migration; positive regulation of T cell proliferation; cell surface receptor signaling pathway (ortholog); ASSOCIATED WITH Corneal Graft Reject1236526215236549956Rat314old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1604616ASIC4acid sensing ion channel subunit family member 4This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and2219507093219538772Human68descriptiongene, protein-coding, REVIEWED [RefSeq]
1602881PDPRpyruvate dehydrogenase phosphatase regulatory subunitPyruvate dehydrogenase complex (PDC) catalyzes the oxidative decarboxylation of pyruvate and links glycolysis to the tricarboxylic acid cycle and fatty acid synthesis. The dephosphorylation and reactivation of PDC is catalyz167011362670163427Human71descriptiongene, protein-coding, REVIEWED [RefSeq]
1348641AHRRaryl hydrocarbon receptor repressorThe protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively sp5321714438285Human201ensembl_gene_symbol , ensembl_full_namegene, protein-coding, REVIEWED [RefSeq]
9046842Ahrraryl-hydrocarbon receptor repressorINVOLVED IN negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); nitric oxide metabolic process (ortholog); ASSOCIATED WITH hypertension (ortholog); Prenatal Exposure Delayed Effects (ortholog); FOUND IN cytosol (ortholoNW_004955504121739191871Chinchilla12ensembl_gene_symbolgene, protein-coding, MODEL [RefSeq]
13921828AHRRaryl hydrocarbon receptor repressorENCODES a protein that exhibits DNA binding (inferred); protein dimerization activity (inferred); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); nitric oxide metabolic process (ortholog); ASSOCIATED WITPig25ensembl_gene_symbolgene, protein-coding, MODEL [RefSeq]
18447372AHRRaryl hydrocarbon receptor repressorENCODES a protein that exhibits DNA binding (inferred); nuclear receptor activity (inferred); protein dimerization activity (inferred); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); nitric oxide metaboGreen Monkey25ensembl_gene_symbol , ensembl_full_namegene, protein-coding, MODEL [RefSeq]
16567698LNPPSlncRNA PDCD5 and p53 scaffoldHumannamegene, lncrna
155882988LNPPSlncRNA PDCD5 and p53 scaffoldHumannamegene, ncrna
1561612Pgcka1PDCD10 and GCKIII kinases associated 1ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN regulation of cell cycle (ortholog); ASSOCIATED WITH cholestasis (ortholog); FOUND IN cell periphery (ortholog); INTERACTS WITH 17beta-estradiol (ortholog); 3-methylcholanthrene (ortholog); 4,4'-sulfonyldiphenol (ortholog)144474096544832180Rat53old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
1602474PGCKA1PDCD10 and GCKIII kinases associated 1INVOLVED IN regulation of cell cycle; ASSOCIATED WITH cholestasis; FOUND IN cell periphery; INTERACTS WITH 17beta-estradiol; 3-methylcholanthrene; 4,4'-sulfonyldiphenol43745325537593510Human52old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
1617462Pgcka1PDCD10 and GCKIII kinases associated 1Is expressed in brain; gut; respiratory system; submandibular gland primordium; and urinary system. Orthologous to human PGCKA1 (PDCD10 and GCKIII kinases associated 1). [provided by Alliance of Genome Resources, Apr 2025]56396983364056968Mouse64old_gene_name , name , descriptiongene, protein-coding, VALIDATED [RefSeq]
8981616Pgcka1PDCD10 and GCKIII kinases associated 1INVOLVED IN regulation of cell cycle (ortholog); ASSOCIATED WITH cholestasis (ortholog); FOUND IN cell periphery (ortholog)NW_00495544395400479628483Chinchilla7namegene, protein-coding, MODEL [RefSeq]
11704093PGCKA1PDCD10 and GCKIII kinases associated 1INVOLVED IN regulation of cell cycle (inferred); ASSOCIATED WITH cholestasis (ortholog); FOUND IN cell periphery (inferred)43178151531922413Bonobo7namegene, protein-coding, MODEL [RefSeq]
12692554Pgcka1PDCD10 and GCKIII kinases associated 1INVOLVED IN regulation of cell cycle (inferred); ASSOCIATED WITH cholestasis (ortholog); FOUND IN cell periphery (inferred)NW_00493648255926675614527Squirrel7namegene, protein-coding, MODEL [RefSeq]
18725637PGCKA1PDCD10 and GCKIII kinases associated 1INVOLVED IN regulation of cell cycle (inferred); ASSOCIATED WITH cholestasis (ortholog); FOUND IN cell periphery (inferred)Green Monkey7namegene, protein-coding, MODEL [RefSeq]
626163965Pgcka1PDCD10 and GCKIII kinases associated 1INVOLVED IN regulation of cell cycle (ortholog); ASSOCIATED WITH cholestasis (ortholog); FOUND IN cell periphery (ortholog)Black Rat7namegene, protein-coding, MODEL [RefSeq]
16562657AC124944.2programmed cell death 6 (PDCD6) pseudogeneHumannamegene, transcribed_unprocessed_pseudogene
16561524AC126177.6programmed cell death 2 (PDCD2) pseudogeneHumannamegene, processed_pseudogene
16570003AC233280.19programmed cell death 6 (PDCD6) pseudogeneHumannamegene, unprocessed_pseudogene
16559702AC087272.1programmed cell death 10 (PDCD10) pseudogeneHumannamegene, processed_pseudogene
16564356AC092073.1novel protein, readthrough between GPI and PDCD2ENCODES a protein that exhibits carbohydrate derivative binding (inferred); glucose-6-phosphate isomerase activity (inferred); INVOLVED IN carbohydrate derivative metabolic process (inferred); gluconeogenesis (inferred); glycolytic process (inferred)Human5namegene, protein-coding
1605963VSIRV-set immunoregulatory receptorEnables endopeptidase activator activity; enzyme binding activity; and identical protein binding activity. Involved in several processes, including negative regulation of cytokine production; positive regulation of metabolic process; and regulation of T cell activation. Located in plasma membrane. [107174755671773520Human109old_gene_namegene, protein-coding, VALIDATED [RefSeq]
16564396LOC124904695uncharacterized LOC124904695193442610634428364Humanold_gene_namegene, ncrna, MODEL [RefSeq]
1320409CHMP4Bcharged multivesicular body protein 4BThis gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors i203381134833854366Human187descriptiongene, protein-coding, REVIEWED [RefSeq]
1606816LILRA4leukocyte immunoglobulin like receptor A4This gene encodes an immunoglobulin-like cell surface protein that is expressed predominantly on plasmacytoid dendritic cells (PDCs) and modulates the function of these cells in the immune response. Expression of this gene is downregulated by interleukin 3 (IL3)195433318554339162Human30descriptiongene, protein-coding, REVIEWED [RefSeq]