PDCD6IP (programmed cell death 6 interacting protein) - Rat Genome Database

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Gene: PDCD6IP (programmed cell death 6 interacting protein) Sus scrofa
Analyze
Symbol: PDCD6IP
Name: programmed cell death 6 interacting protein
RGD ID: 14134841
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein dimerization activity (ortholog); SH3 domain binding (ortholog); INVOLVED IN actomyosin contractile ring assembly (ortholog); bicellular tight junction assembly (ortholog); extracellular exosome biogenesis (ortholog); ASSOCIATED WITH genetic disease (ortholog); osteoarthritis (ortholog); Primary Autosomal Recessive Microcephaly 29 (ortholog); FOUND IN actomyosin (ortholog); cytosol (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: programmed cell death 6-interacting protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1319,597,059 - 19,665,996 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11319,597,064 - 19,664,047 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21321,193,109 - 21,243,506 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:14681463   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PDCD6IP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1319,597,059 - 19,665,996 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11319,597,064 - 19,664,047 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21321,193,109 - 21,243,506 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PDCD6IP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38333,798,630 - 33,869,703 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl333,798,571 - 33,869,707 (+)EnsemblGRCh38hg38GRCh38
GRCh37333,840,122 - 33,911,195 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36333,814,561 - 33,886,198 (+)NCBINCBI36Build 36hg18NCBI36
Build 34333,814,560 - 33,886,198NCBI
Celera333,783,127 - 33,854,073 (+)NCBICelera
Cytogenetic Map3p22.3NCBI
HuRef333,781,264 - 33,852,387 (+)NCBIHuRef
CHM1_1333,789,988 - 33,861,201 (+)NCBICHM1_1
T2T-CHM13v2.0333,799,362 - 33,870,437 (+)NCBIT2T-CHM13v2.0
Pdcd6ip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399113,480,812 - 113,537,457 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9113,480,812 - 113,537,327 (-)EnsemblGRCm39 Ensembl
GRCm389113,651,744 - 113,708,279 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9113,651,744 - 113,708,259 (-)EnsemblGRCm38mm10GRCm38
MGSCv379113,560,862 - 113,617,377 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369113,503,631 - 113,556,805 (-)NCBIMGSCv36mm8
Celera9113,360,961 - 113,417,417 (-)NCBICelera
Cytogenetic Map9F3NCBI
cM Map964.03NCBI
Pdcd6ip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88122,469,223 - 122,524,993 (-)NCBIGRCr8
mRatBN7.28113,590,998 - 113,646,795 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8113,590,998 - 113,646,773 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8119,207,150 - 119,262,921 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08117,406,414 - 117,462,188 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08115,249,172 - 115,304,948 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08121,916,233 - 121,973,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8121,916,185 - 121,973,125 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08121,231,793 - 121,287,105 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48118,314,910 - 118,350,134 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera8112,840,809 - 112,895,775 (-)NCBICelera
Cytogenetic Map8q32NCBI
Pdcd6ip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554211,034,843 - 1,110,438 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554211,034,843 - 1,109,637 (+)NCBIChiLan1.0ChiLan1.0
PDCD6IP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2233,773,923 - 33,847,614 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1333,778,883 - 33,852,381 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0333,719,603 - 33,793,301 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1334,016,152 - 34,093,631 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl334,016,474 - 34,093,631 (+)Ensemblpanpan1.1panPan2
PDCD6IP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1234,112,299 - 4,199,230 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl234,112,363 - 4,196,342 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha234,154,337 - 4,240,985 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0234,374,570 - 4,462,420 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1234,207,505 - 4,294,589 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0234,339,176 - 4,426,011 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0234,308,530 - 4,395,465 (+)NCBIUU_Cfam_GSD_1.0
Pdcd6ip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118190,870,278 - 190,948,263 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647324,010,935 - 24,086,846 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647324,010,942 - 24,086,836 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDCD6IP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11578,265,099 - 78,339,307 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1578,265,252 - 78,339,873 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604151,646,595 - 51,721,427 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pdcd6ip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478811,772,396 - 11,845,765 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478811,772,268 - 11,849,040 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PDCD6IP
2585 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 2 3 5 2 23 2 3 3
Low 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000012304   ⟹   ENSSSCP00000011985
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1319,597,115 - 19,661,164 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000043902   ⟹   ENSSSCP00000035657
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1319,597,108 - 19,661,161 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000049951   ⟹   ENSSSCP00000039055
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1319,597,059 - 19,665,996 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000057076   ⟹   ENSSSCP00000043173
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1319,597,141 - 19,664,043 (+)Ensembl
RefSeq Acc Id: XM_021071621   ⟹   XP_020927280
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11319,597,100 - 19,664,047 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021071622   ⟹   XP_020927281
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11319,597,064 - 19,664,047 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020927281   ⟸   XM_021071622
- Peptide Label: isoform X2
- UniProtKB: A0A287AH24 (UniProtKB/TrEMBL),   A0A8D0Q6F4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020927280   ⟸   XM_021071621
- Peptide Label: isoform X1
- UniProtKB: A0A8D0Q6H0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000043173   ⟸   ENSSSCT00000057076
RefSeq Acc Id: ENSSSCP00000035657   ⟸   ENSSSCT00000043902
RefSeq Acc Id: ENSSSCP00000039055   ⟸   ENSSSCT00000049951
RefSeq Acc Id: ENSSSCP00000011985   ⟸   ENSSSCT00000012304
Protein Domains
BRO1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011237 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005018804 UniProtKB/TrEMBL
  ENSSSCG00015078134 UniProtKB/TrEMBL
  ENSSSCG00025016973 UniProtKB/TrEMBL
  ENSSSCG00030022135 UniProtKB/TrEMBL
  ENSSSCG00035045572 UniProtKB/TrEMBL
  ENSSSCG00040011374 UniProtKB/TrEMBL
  ENSSSCG00045005223 UniProtKB/TrEMBL
  ENSSSCG00050037147 UniProtKB/TrEMBL
  ENSSSCG00055029884 UniProtKB/TrEMBL
  ENSSSCG00060014999 UniProtKB/TrEMBL
  ENSSSCG00065021109 UniProtKB/TrEMBL
  ENSSSCG00070014992 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000012304.5 UniProtKB/TrEMBL
  ENSSSCT00000049951.3 UniProtKB/TrEMBL
  ENSSSCT00000057076 ENTREZGENE
  ENSSSCT00000057076.2 UniProtKB/TrEMBL
  ENSSSCT00005030410.1 UniProtKB/TrEMBL
  ENSSSCT00005030431.1 UniProtKB/TrEMBL
  ENSSSCT00005030503.1 UniProtKB/TrEMBL
  ENSSSCT00005030549.1 UniProtKB/TrEMBL
  ENSSSCT00015105667.1 UniProtKB/TrEMBL
  ENSSSCT00015105684.1 UniProtKB/TrEMBL
  ENSSSCT00015105762.1 UniProtKB/TrEMBL
  ENSSSCT00015105857.1 UniProtKB/TrEMBL
  ENSSSCT00015105918.1 UniProtKB/TrEMBL
  ENSSSCT00025022977.1 UniProtKB/TrEMBL
  ENSSSCT00030030707.1 UniProtKB/TrEMBL
  ENSSSCT00030030712.1 UniProtKB/TrEMBL
  ENSSSCT00030030725.1 UniProtKB/TrEMBL
  ENSSSCT00030030732.1 UniProtKB/TrEMBL
  ENSSSCT00035060576.1 UniProtKB/TrEMBL
  ENSSSCT00035060582.1 UniProtKB/TrEMBL
  ENSSSCT00035060585.1 UniProtKB/TrEMBL
  ENSSSCT00035060596.1 UniProtKB/TrEMBL
  ENSSSCT00040014870.1 UniProtKB/TrEMBL
  ENSSSCT00040014891.1 UniProtKB/TrEMBL
  ENSSSCT00040014926.1 UniProtKB/TrEMBL
  ENSSSCT00040014963.1 UniProtKB/TrEMBL
  ENSSSCT00040014992.1 UniProtKB/TrEMBL
  ENSSSCT00040015045.1 UniProtKB/TrEMBL
  ENSSSCT00045008681.1 UniProtKB/TrEMBL
  ENSSSCT00045008690.1 UniProtKB/TrEMBL
  ENSSSCT00045008695.1 UniProtKB/TrEMBL
  ENSSSCT00045008701.1 UniProtKB/TrEMBL
  ENSSSCT00050050007.1 UniProtKB/TrEMBL
  ENSSSCT00050050015.1 UniProtKB/TrEMBL
  ENSSSCT00050050022.1 UniProtKB/TrEMBL
  ENSSSCT00050050027.1 UniProtKB/TrEMBL
  ENSSSCT00055059409.1 UniProtKB/TrEMBL
  ENSSSCT00055059414.1 UniProtKB/TrEMBL
  ENSSSCT00055059447.1 UniProtKB/TrEMBL
  ENSSSCT00055059481.1 UniProtKB/TrEMBL
  ENSSSCT00055059513.1 UniProtKB/TrEMBL
  ENSSSCT00055059532.1 UniProtKB/TrEMBL
  ENSSSCT00060019915.1 UniProtKB/TrEMBL
  ENSSSCT00060019934.1 UniProtKB/TrEMBL
  ENSSSCT00065028089.1 UniProtKB/TrEMBL
  ENSSSCT00065028094.1 UniProtKB/TrEMBL
  ENSSSCT00065028105.1 UniProtKB/TrEMBL
  ENSSSCT00065028113.1 UniProtKB/TrEMBL
  ENSSSCT00070029582.1 UniProtKB/TrEMBL
  ENSSSCT00070029642.1 UniProtKB/TrEMBL
  ENSSSCT00070029655.1 UniProtKB/TrEMBL
  ENSSSCT00070029689.1 UniProtKB/TrEMBL
  ENSSSCT00070029704.1 UniProtKB/TrEMBL
  ENSSSCT00070029722.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.280 UniProtKB/TrEMBL
  alix/aip1 in complex with the ypdl late domain UniProtKB/TrEMBL
  alix/aip1 like domains UniProtKB/TrEMBL
InterPro ALIX_V_dom UniProtKB/TrEMBL
  BRO1-like UniProtKB/TrEMBL
  BRO1_dom UniProtKB/TrEMBL
  BRO1_sf UniProtKB/TrEMBL
NCBI Gene PDCD6IP ENTREZGENE
PANTHER PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN UniProtKB/TrEMBL
  PTHR23030 UniProtKB/TrEMBL
Pfam ALIX_LYPXL_bnd UniProtKB/TrEMBL
  BRO1 UniProtKB/TrEMBL
PRINTS PRICHEXTENSN UniProtKB/TrEMBL
PROSITE BRO1 UniProtKB/TrEMBL
SMART BRO1 UniProtKB/TrEMBL
UniProt A0A287A5B4_PIG UniProtKB/TrEMBL
  A0A287AH24 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1U4U5_PIG UniProtKB/TrEMBL
  A0A4X1U4Y6_PIG UniProtKB/TrEMBL
  A0A4X1U503_PIG UniProtKB/TrEMBL
  A0A4X1U723_PIG UniProtKB/TrEMBL
  A0A4X1U990_PIG UniProtKB/TrEMBL
  A0A4X1U9Z6_PIG UniProtKB/TrEMBL
  A0A8D0IXC5_PIG UniProtKB/TrEMBL
  A0A8D0IZC4_PIG UniProtKB/TrEMBL
  A0A8D0J4V5_PIG UniProtKB/TrEMBL
  A0A8D0Q6F4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Q6H0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0QB30_PIG UniProtKB/TrEMBL
  A0A8D0UE30_PIG UniProtKB/TrEMBL
  A0A8D0VZJ6_PIG UniProtKB/TrEMBL
  A0A8D1A574_PIG UniProtKB/TrEMBL
  A0A8D1DED3_PIG UniProtKB/TrEMBL
  A0A8D1DEI2_PIG UniProtKB/TrEMBL
  A0A8D1DEK0_PIG UniProtKB/TrEMBL
  A0A8D1DF27_PIG UniProtKB/TrEMBL
  A0A8D1GMS2_PIG UniProtKB/TrEMBL
  A0A8D1GSI7_PIG UniProtKB/TrEMBL
  A0A8D1MCN1_PIG UniProtKB/TrEMBL
  A0A8D1SHV7_PIG UniProtKB/TrEMBL
  F1RRD6_PIG UniProtKB/TrEMBL
VGNC ID VGNC:106452 ENTREZGENE