Pdcd6 (programmed cell death 6) - Rat Genome Database

Name: Pdcd6
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Pdcd6 (programmed cell death 6) Ictidomys tridecemlineatus

Analyze

Symbol:

Pdcd6

Name:

programmed cell death 6

RGD ID:

12625271

Description:

ENCODES a protein that exhibits protein heterodimerization activity (ortholog); INVOLVED IN apoptotic process (ortholog); ASSOCIATED WITH dopamine transporter deficiency syndrome (ortholog); genetic disease (ortholog); idiopathic pulmonary fibrosis (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

programmed cell death 6, transcript variant X1; programmed cell death 6, transcript variant X2; programmed cell death 6, transcript variant X3; programmed cell death 6, transcript variant X4; programmed cell death protein 6

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PDCD6 (programmed cell death 6)	NCBI	Ortholog
Mus musculus (house mouse):	Pdcd6 (programmed cell death 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Pdcd6 (programmed cell death 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pdcd6 (programmed cell death 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PDCD6 (programmed cell death 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PDCD6 (programmed cell death 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PDCD6 (programmed cell death 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PDCD6 (programmed cell death 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pdcd6 (programmed cell death 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	244,968,082 - 244,982,736 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936815	1,129,352 - 1,143,992 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936815	1,129,367 - 1,144,020 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

dopamine transporter deficiency syndrome (ISO)

genetic disease (ISO)

idiopathic pulmonary fibrosis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic process (IEA,ISO)

cellular response to heat (IEA)

COPII vesicle coating (IEA)

endoplasmic reticulum to Golgi vesicle-mediated transport (IEA)

intracellular protein transport (IEA)

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (IEA)

negative regulation of TOR signaling (IEA)

negative regulation of vascular endothelial growth factor receptor signaling pathway (IEA)

neural crest cell development (IEA)

neural crest formation (IEA)

positive regulation of angiogenesis (IEA)

positive regulation of endothelial cell migration (IEA)

positive regulation of endothelial cell proliferation (IEA)

positive regulation of protein monoubiquitination (IEA)

response to calcium ion (IEA)

vascular endothelial growth factor receptor-2 signaling pathway (IEA)

Cellular Component

COPII vesicle coat (IEA)

Cul3-RING ubiquitin ligase complex (IEA)

cytoplasm (IEA)

cytoplasmic vesicle (IEA)

cytosol (IEA)

endoplasmic reticulum (IEA)

endoplasmic reticulum exit site (IEA)

nucleoplasm (IEA)

nucleus (IEA)

perinuclear region of cytoplasm (ISO)

Molecular Function

calcium ion binding (IEA)

calcium-dependent protein binding (IEA)

identical protein binding (IEA)

magnesium ion binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

protein dimerization activity (IEA)

protein heterodimerization activity (ISO)

protein homodimerization activity (IEA)

protein-macromolecule adaptor activity (IEA)

protein-membrane adaptor activity (IEA)

ubiquitin-like ligase-substrate adaptor activity (IEA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Pdcd6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	244,968,082 - 244,982,736 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936815	1,129,352 - 1,143,992 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936815	1,129,367 - 1,144,020 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PDCD6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	271,646 - 314,974 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	271,621 - 314,974 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	271,761 - 315,089 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	324,736 - 368,089 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	324,738 - 368,089	NCBI
Celera	5	370,282 - 413,335 (+)	NCBI		Celera
Cytogenetic Map	5	p15.33	NCBI
HuRef	5	258,986 - 302,543 (+)	NCBI		HuRef
CHM1_1	5	267,028 - 314,783 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	261,673 - 305,205 (+)	NCBI		T2T-CHM13v2.0

Pdcd6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	74,451,240 - 74,465,445 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	74,451,628 - 74,465,699 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	74,303,121 - 74,317,326 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	74,303,509 - 74,317,580 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	74,440,569 - 74,454,774 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	74,769,130 - 74,790,911 (-)	NCBI		MGSCv36	mm8
Celera	13	76,632,567 - 76,646,789 (-)	NCBI		Celera
Cytogenetic Map	13	C1	NCBI
cM Map	13	40.15	NCBI

Pdcd6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	30,795,105 - 30,810,771 (+)	NCBI		GRCr8
mRatBN7.2	1	28,966,518 - 28,982,188 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	28,966,518 - 28,982,189 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	28,767,781 - 28,783,445 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	34,767,645 - 34,783,309 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	28,968,411 - 28,984,075 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	31,576,183 - 31,591,852 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	31,576,183 - 31,591,849 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	33,002,331 - 33,017,997 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	29,769,911 - 29,785,577 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	29,772,917 - 29,788,523 (+)	NCBI
Celera	1	27,618,297 - 27,633,964 (+)	NCBI		Celera
Cytogenetic Map	1	p11	NCBI

Pdcd6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955504	74,944 - 98,282 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955504	75,378 - 94,654 (+)	NCBI	ChiLan1.0	ChiLan1.0

PDCD6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	490,544 - 533,958 (+)	NCBI		NHGRI_mPanPan1-v2

PDCD6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	11,909,657 - 11,929,850 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	11,909,934 - 11,929,855 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	16,422,880 - 16,443,067 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	11,811,327 - 11,831,550 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	11,811,327 - 11,831,555 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	11,864,243 - 11,884,414 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	11,850,310 - 11,870,511 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	12,052,312 - 12,072,529 (-)	NCBI		UU_Cfam_GSD_1.0

PDCD6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	79,818,958 - 79,835,746 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	79,818,960 - 79,832,272 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

PDCD6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	204,512 - 215,059 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	200,926 - 214,718 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666064	27,331,351 - 27,341,948 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pdcd6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624751	99,860 - 120,963 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624751	99,835 - 120,963 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005340738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005340739	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005340740	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021720515	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010002273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000026466 ⟹ ENSSTOP00000023713

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936815	1,129,825 - 1,143,945 (-)	Ensembl

RefSeq Acc Id:

ENSSTOT00000035402 ⟹ ENSSTOP00000026996

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936815	1,129,352 - 1,143,992 (-)	Ensembl

RefSeq Acc Id:

XM_005340738 ⟹ XP_005340795

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	244,968,082 - 244,982,735 (-)	NCBI
SpeTri2.0	NW_004936815	1,129,367 - 1,144,006 (-)	NCBI

Sequence:

show sequence

CCAGCAGAGGCGGAAGTGGAGCCGCCCGAGTCTTGCCGCGTTGCCGCCGGTTCCAGGGTCCATG
GCCGCCTACTCCTATCGCCCTGGCCCGGGTTCCGGCCCGGGCCCAGCTGCGGGCGCGGCGTTGC
CGGACCAGAGCTTCCTGTGGAACGTCTTCCAGCGAGTTGATAAAGACAGGAGTGGGGTGATATC
GGACAGTGAGCTTCAGCAGGCGCTATCCAATGGCACATGGACCCCGTTTAACCCAGTGACTGTC
AGGTCAATCATTTCTATGTTTGACCGGGAGAACAAGGCTGGCGTGAACTTCAGCGAATTCACAG
GCGTGTGGAAGTACATCACAGACTGGCAGAATGTCTTCCGCACCTATGACAGGGACAACTCTGG
AATGATCGACAAGAACGAGCTCAAGCAAGCACTCTCAGGTTTTGGCTATCGGCTCTCTGACCAG
TTCCACGACATCCTCATTCGGAAATTTGACAGACAAGGACGAGGGCAGATTGCCTTTGATGACT
TCATCCAGGGCTGCATTGTCTTACAGAGGTTGACGGACATATTCAGACGTTACGACACGGATCA
AGATGGCTGGATTCAGGTGTCCTATGAGCAGTATCTCTCCATGGTCTTCAGCATTGTATAATGC
ACGCCTTGTGGACAGCAGCACATCATATGAGAAAAGACTGAAAATGCCAAATTCCTTCCCTGTA
ACAAATGGGGACCCAGATGCAGTTAGATGCTGTTCTTCCGTCGGATCTTGTGTAGTTAACACTT
GGGGACCTGGCTGTACATATGTGGATAAGCTGACTACGGCTTTGCAGTCGTAGCAGCCACCATG
TCAACATAAGAAACACTGGGTTTGCTGGCCTGCTGATTGTGCCATGAGGCGAAACCTAATAATG
GTTCAGGTGTTCTCCCAAAATGCATCATGTACTTTCCTCGATCTCCAGTTCTGTAGTGGAAATG
CTTTTATCAGCCAATAGAATTTTTAAGTGAAATGAACTTGCACAGAGGCTTTCACGTGCCTTAC
TTTTCTAAAAGGAGTTTATTGTATTCATTGGAATAGGCAACATAAGCAATAAAGTAAAGGTACA
GACTCAA

hide sequence

RefSeq Acc Id:

XM_005340739 ⟹ XP_005340796

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	244,968,082 - 244,982,736 (-)	NCBI
SpeTri2.0	NW_004936815	1,129,367 - 1,144,006 (-)	NCBI

Sequence:

show sequence

CCAGCAGAGGCGGAAGTGGAGCCGCCCGAGTCTTGCCGCGTTGCCGCCGGTTCCAGGGTCCATG
GCCGCCTACTCCTATCGCCCTGGCCCGGGTTCCGGCCCGGGCCCAGCTGCGGGCGCGGCGTTGC
CGGACCAGAGCTTCCTGTGGAACGTCTTCCAGCGAGTTGATAAAGACAGGAGTGGGGTGATATC
GGACAGTGAGCTTCAGCAGGCGCTATCCAATGGCACATGGACCCCGTTTAACCCAGTGACTGTC
AGGTCAATCATTTCTATGTTTGACCGGGAGAACAAGGCTGGCGTGAACTTCAGCGAATTCACAG
GCGTGTGGAAGTACATCACAGACTGGCAGAATGTCTTCCGCACCTATGACAGGGACAACTCTGG
AATGATCGACAAGAACGAGCTCAAGCAAGCACTCTCAGGCTATCGGCTCTCTGACCAGTTCCAC
GACATCCTCATTCGGAAATTTGACAGACAAGGACGAGGGCAGATTGCCTTTGATGACTTCATCC
AGGGCTGCATTGTCTTACAGAGGTTGACGGACATATTCAGACGTTACGACACGGATCAAGATGG
CTGGATTCAGGTGTCCTATGAGCAGTATCTCTCCATGGTCTTCAGCATTGTATAATGCACGCCT
TGTGGACAGCAGCACATCATATGAGAAAAGACTGAAAATGCCAAATTCCTTCCCTGTAACAAAT
GGGGACCCAGATGCAGTTAGATGCTGTTCTTCCGTCGGATCTTGTGTAGTTAACACTTGGGGAC
CTGGCTGTACATATGTGGATAAGCTGACTACGGCTTTGCAGTCGTAGCAGCCACCATGTCAACA
TAAGAAACACTGGGTTTGCTGGCCTGCTGATTGTGCCATGAGGCGAAACCTAATAATGGTTCAG
GTGTTCTCCCAAAATGCATCATGTACTTTCCTCGATCTCCAGTTCTGTAGTGGAAATGCTTTTA
TCAGCCAATAGAATTTTTAAGTGAAATGAACTTGCACAGAGGCTTTCACGTGCCTTACTTTTCT
AAAAGGAGTTTATTGTATTCATTGGAATAGGCAACATAAGCAATAAAGTAAAGGTACAGACTCA
A

hide sequence

RefSeq Acc Id:

XM_005340740 ⟹ XP_005340797

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	244,968,082 - 244,982,692 (-)	NCBI
SpeTri2.0	NW_004936815	1,129,367 - 1,144,018 (-)	NCBI

Sequence:

show sequence

CAGGCTCCGCCCCCAGCAGAGGCGGAAGTGGAGCCGCCCGAGTCTTGCCGCGTTGCCGCCGGTT
CCAGGGTCCATGGCCGCCTACTCCTATCGCCCTGGCCCGGGTTCCGGCCCGGGCCCAGCTGCGG
GCGCGGCGTTGCCGGACCAGAGCTTCCTGTGGAACGTCTTCCAGCGGCACATGGACCCCGTTTA
ACCCAGTGACTGTCAGGTCAATCATTTCTATGTTTGACCGGGAGAACAAGGCTGGCGTGAACTT
CAGCGAATTCACAGGCGTGTGGAAGTACATCACAGACTGGCAGAATGTCTTCCGCACCTATGAC
AGGGACAACTCTGGAATGATCGACAAGAACGAGCTCAAGCAAGCACTCTCAGGTTTTGGCTATC
GGCTCTCTGACCAGTTCCACGACATCCTCATTCGGAAATTTGACAGACAAGGACGAGGGCAGAT
TGCCTTTGATGACTTCATCCAGGGCTGCATTGTCTTACAGAGGTTGACGGACATATTCAGACGT
TACGACACGGATCAAGATGGCTGGATTCAGGTGTCCTATGAGCAGTATCTCTCCATGGTCTTCA
GCATTGTATAATGCACGCCTTGTGGACAGCAGCACATCATATGAGAAAAGACTGAAAATGCCAA
ATTCCTTCCCTGTAACAAATGGGGACCCAGATGCAGTTAGATGCTGTTCTTCCGTCGGATCTTG
TGTAGTTAACACTTGGGGACCTGGCTGTACATATGTGGATAAGCTGACTACGGCTTTGCAGTCG
TAGCAGCCACCATGTCAACATAAGAAACACTGGGTTTGCTGGCCTGCTGATTGTGCCATGAGGC
GAAACCTAATAATGGTTCAGGTGTTCTCCCAAAATGCATCATGTACTTTCCTCGATCTCCAGTT
CTGTAGTGGAAATGCTTTTATCAGCCAATAGAATTTTTAAGTGAAATGAACTTGCACAGAGGCT
TTCACGTGCCTTACTTTTCTAAAAGGAGTTTATTGTATTCATTGGAATAGGCAACATAAGCAAT
AAAGTAAAGGTACAGACTCAA

hide sequence

RefSeq Acc Id:

XM_021720515 ⟹ XP_021576190

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	244,968,082 - 244,982,696 (-)	NCBI
SpeTri2.0	NW_004936815	1,129,367 - 1,144,020 (-)	NCBI

Sequence:

show sequence

GCCAGGCTCCGCCCCCAGCAGAGGCGGAAGTGGAGCCGCCCGAGTCTTGCCGCGTTGCCGCCGG
TTCCAGGGTCCATGGCCGCCTACTCCTATCGCCCTGGCCCGGGTTCCGGCCCGGGCCCAGCTGC
GGGCGCGGCGTTGCCGGACCAGAGCTTCCTGTGGAACGTCTTCCAGCGGCACATGGACCCCGTT
TAACCCAGTGACTGTCAGGTCAATCATTTCTATGTTTGACCGGGAGAACAAGGCTGGCGTGAAC
TTCAGCGAATTCACAGGCGTGTGGAAGTACATCACAGACTGGCAGAATGTCTTCCGCACCTATG
ACAGGGACAACTCTGGAATGATCGACAAGAACGAGCTCAAGCAAGCACTCTCAGGCTATCGGCT
CTCTGACCAGTTCCACGACATCCTCATTCGGAAATTTGACAGACAAGGACGAGGGCAGATTGCC
TTTGATGACTTCATCCAGGGCTGCATTGTCTTACAGAGGTTGACGGACATATTCAGACGTTACG
ACACGGATCAAGATGGCTGGATTCAGGTGTCCTATGAGCAGTATCTCTCCATGGTCTTCAGCAT
TGTATAATGCACGCCTTGTGGACAGCAGCACATCATATGAGAAAAGACTGAAAATGCCAAATTC
CTTCCCTGTAACAAATGGGGACCCAGATGCAGTTAGATGCTGTTCTTCCGTCGGATCTTGTGTA
GTTAACACTTGGGGACCTGGCTGTACATATGTGGATAAGCTGACTACGGCTTTGCAGTCGTAGC
AGCCACCATGTCAACATAAGAAACACTGGGTTTGCTGGCCTGCTGATTGTGCCATGAGGCGAAA
CCTAATAATGGTTCAGGTGTTCTCCCAAAATGCATCATGTACTTTCCTCGATCTCCAGTTCTGT
AGTGGAAATGCTTTTATCAGCCAATAGAATTTTTAAGTGAAATGAACTTGCACAGAGGCTTTCA
CGTGCCTTACTTTTCTAAAAGGAGTTTATTGTATTCATTGGAATAGGCAACATAAGCAATAAAG
TAAAGGTACAGACTCAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005340795	(Get FASTA)	NCBI Sequence Viewer
	XP_005340796	(Get FASTA)	NCBI Sequence Viewer
	XP_005340797	(Get FASTA)	NCBI Sequence Viewer
	XP_021576190	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000023713.2
	ENSSTOP00000026996.1
GenBank Protein	KAG3266941	(Get FASTA)	NCBI Sequence Viewer
	KAG3266942	(Get FASTA)	NCBI Sequence Viewer
	KAG3266943	(Get FASTA)	NCBI Sequence Viewer
	KAG3266944	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005340796 ⟸ XM_005340739
- Peptide Label:	isoform X4
- UniProtKB:	I3NH66 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAYSYRPGPGSGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDSELQQALSNGTWTPFNPVT VRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGYRLSDQF HDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV hide sequence

RefSeq Acc Id:	XP_005340795 ⟸ XM_005340738
- Peptide Label:	isoform X3
- UniProtKB:	A0A287D081 (UniProtKB/TrEMBL), I3NH66 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAYSYRPGPGSGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDSELQQALSNGTWTPFNPVT VRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSD QFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV hide sequence

RefSeq Acc Id:	XP_005340797 ⟸ XM_005340740
- Peptide Label:	isoform X1
- Sequence:	show sequence MFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDIL IRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV hide sequence

RefSeq Acc Id:	XP_021576190 ⟸ XM_021720515
- Peptide Label:	isoform X2
- Sequence:	show sequence MFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGYRLSDQFHDILIR KFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV hide sequence

RefSeq Acc Id:

ENSSTOP00000023713 ⟸ ENSSTOT00000026466

RefSeq Acc Id:

ENSSTOP00000026996 ⟸ ENSSTOT00000035402

Protein Domains

EF-hand

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000028872	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000026466.2	UniProtKB/TrEMBL
	ENSSTOT00000035402.1	UniProtKB/TrEMBL
Gene3D-CATH	EF-hand	UniProtKB/TrEMBL
InterPro	EF-hand-dom_pair	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_dom	UniProtKB/TrEMBL
NCBI Gene	Pdcd6	ENTREZGENE
PANTHER	PEFLIN	UniProtKB/TrEMBL
	PROGRAMMED CELL DEATH PROTEIN 6	UniProtKB/TrEMBL
Pfam	EF-hand_5	UniProtKB/TrEMBL
	EF-hand_7	UniProtKB/TrEMBL
PROSITE	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
SMART	EFh	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47473	UniProtKB/TrEMBL
UniProt	A0A287D081	ENTREZGENE, UniProtKB/TrEMBL
	I3NH66	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar