Pdcd4 (programmed cell death 4) - Rat Genome Database

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Gene: Pdcd4 (programmed cell death 4) Ictidomys tridecemlineatus
Analyze
Symbol: Pdcd4
Name: programmed cell death 4
RGD ID: 12613974
Description: INVOLVED IN epithelial to mesenchymal transition involved in cardiac fibroblast development (ortholog); negative regulation of apoptotic process (ortholog); obsolete cell aging (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Arterial Injury (ortholog); dilated cardiomyopathy 1DD (ortholog); Lung Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721323,855,886 - 23,877,135 (-)NCBI
SpeTri2.0NW_0049364861,684,167 - 1,705,387 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Pdcd4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721323,855,886 - 23,877,135 (-)NCBI
SpeTri2.0NW_0049364861,684,167 - 1,705,387 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDCD4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810110,871,928 - 110,900,006 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl10110,871,795 - 110,900,006 (+)EnsemblGRCh38hg38GRCh38
GRCh3710112,631,686 - 112,659,764 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610112,621,586 - 112,649,754 (+)NCBINCBI36hg18NCBI36
Build 3410112,621,585 - 112,649,753NCBI
Celera10106,363,204 - 106,391,372 (+)NCBI
Cytogenetic Map10q25.2NCBI
HuRef10106,260,410 - 106,288,621 (+)NCBIHuRef
CHM1_110112,913,378 - 112,941,587 (+)NCBICHM1_1
T2T-CHM13v2.010111,755,712 - 111,783,789 (+)NCBI
Pdcd4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391953,880,662 - 53,926,024 (+)NCBIGRCm39mm39
GRCm39 Ensembl1953,880,662 - 53,918,291 (+)Ensembl
GRCm381953,892,231 - 53,937,592 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1953,892,231 - 53,929,860 (+)EnsemblGRCm38mm10GRCm38
MGSCv371953,966,721 - 54,004,351 (+)NCBIGRCm37mm9NCBIm37
MGSCv361953,956,779 - 53,983,162 (+)NCBImm8
Celera1956,087,143 - 56,124,829 (+)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1948.73NCBI
Pdcd4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21252,921,342 - 252,944,278 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1252,921,392 - 252,944,275 (+)Ensembl
Rnor_6.01274,616,625 - 274,648,204 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1274,625,224 - 274,648,204 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01282,029,865 - 282,061,732 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41260,183,648 - 260,202,032 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11260,394,692 - 260,413,077 (+)NCBI
Celera1248,639,428 - 248,657,812 (+)NCBICelera
Cytogenetic Map1q55NCBI
Pdcd4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955485529,860 - 553,601 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955485530,642 - 553,508 (-)NCBIChiLan1.0ChiLan1.0
PDCD4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.110110,914,222 - 110,942,394 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10110,914,222 - 110,942,394 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v010107,465,084 - 107,493,285 (+)NCBIMhudiblu_PPA_v0panPan3
PDCD4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12822,198,274 - 22,227,184 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2822,198,322 - 22,226,717 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2822,350,385 - 22,379,252 (+)NCBI
ROS_Cfam_1.02822,722,838 - 22,751,713 (+)NCBI
ROS_Cfam_1.0 Ensembl2822,722,897 - 22,752,395 (+)Ensembl
UMICH_Zoey_3.12822,282,298 - 22,310,940 (+)NCBI
UNSW_CanFamBas_1.02822,289,098 - 22,317,724 (+)NCBI
UU_Cfam_GSD_1.02822,423,221 - 22,451,894 (+)NCBI
PDCD4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14121,305,629 - 121,338,740 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114121,271,824 - 121,334,767 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214132,232,416 - 132,261,645 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PDCD4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19103,809,005 - 103,836,402 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl9103,813,211 - 103,836,002 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604865,014,586 - 65,042,439 (+)NCBIVero_WHO_p1.0
Pdcd4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473735,414,078 - 35,451,023 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005320668   ⟹   XP_005320725
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721323,855,886 - 23,877,135 (-)NCBI
SpeTri2.0NW_0049364861,684,167 - 1,705,387 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040272676   ⟹   XP_040128610
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721323,855,886 - 23,877,135 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005320725 (Get FASTA)   NCBI Sequence Viewer  
  XP_040128610 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3264103 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005320725   ⟸   XM_005320668
- Peptide Label: isoform X1
- UniProtKB: A0A287D7M7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040128610   ⟸   XM_040272676
- Peptide Label: isoform X2
Protein Domains
MI


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000015625 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000013987.3 UniProtKB/TrEMBL
  ENSSTOP00000029539 ENTREZGENE
  ENSSTOP00000029539.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000015625.3 UniProtKB/TrEMBL
  ENSSTOT00000035649.1 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  Initiation_fac_eIF4g_MI UniProtKB/TrEMBL
  PDCD4 UniProtKB/TrEMBL
NCBI Gene Pdcd4 ENTREZGENE
PANTHER PTHR12626 UniProtKB/TrEMBL
Pfam MA3 UniProtKB/TrEMBL
PROSITE PS51366 UniProtKB/TrEMBL
SMART MA3 UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A287D7M7 ENTREZGENE, UniProtKB/TrEMBL
  I3MQ25_ICTTR UniProtKB/TrEMBL