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Gene: Nphs2 (nephrosis 2, podocin) Mus musculus
Symbol: Nphs2
Name: nephrosis 2, podocin
Description: Predicted to be involved in actin cytoskeleton reorganization. Localizes to intrinsic component of the cytoplasmic side of the plasma membrane. Colocalizes with slit diaphragm. Used to study nephrotic syndrome. Human ortholog(s) of this gene implicated in nephrotic syndrome type 2. Is expressed in liver and metanephros. Orthologous to human NPHS2 (NPHS2 stomatin family member, podocin); INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI790225; nephrosis 2 homolog, podocin; PDCN; podocin; SRN1
Homo sapiens (human) : NPHS2 (NPHS2 stomatin family member, podocin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nphs2 (NPHS2 stomatin family member, podocin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nphs2 (NPHS2 stomatin family member, podocin)
Canis lupus familiaris (dog) : NPHS2 (NPHS2 stomatin family member, podocin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nphs2 (NPHS2 stomatin family member, podocin)
Sus scrofa (pig) : NPHS2 (NPHS2 stomatin family member, podocin)
Chlorocebus sabaeus (African green monkey) : NPHS2 (NPHS2 stomatin family member, podocin)
Heterocephalus glaber (naked mole-rat) : Nphs2 (NPHS2 stomatin family member, podocin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1156,310,727 - 156,328,035 (+)EnsemblGRCm38mm10GRCm38
GRCm381156,310,535 - 156,328,035 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371158,240,866 - 158,258,166 (+)NCBIGRCm37mm9NCBIm37
MGSCv361158,147,412 - 158,164,712 (+)NCBImm8
Celera1158,706,623 - 158,724,043 (+)NCBICelera
Cytogenetic Map1G3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Nphs2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732449
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.