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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:fatty acid beta degradation pathway
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Accession:PW:0000738 term browser browse the term
Definition:Fatty acid degradation via beta oxidation, the most common fatty acid degradation pathway, occurs in four reactions resulting in the formation of acetyl-CoA and a fatty acyl-CoA two carbon shorter than the one that began the cycle. Acetyl-CoA can undergo further oxidation via the Krebs cycle or can be converted to ketone bodies.
Synonyms:related_synonym: SMP:00052;   SMP:00480;   SMP:00481;   SMP:00482;   fatty acid beta oxidation pathway
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fatty acid beta degradation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 ISO SMPDB SMP:00052 NCBI chr  X:156,579,669...156,601,448
Ensembl chr  X:151,428,578...151,450,115 		JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 ISO SMPDB SMP:00052 NCBI chr 7:124,142,597...124,191,202
Ensembl chr 7:122,263,032...122,311,642 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 IDA
ISO		 SMPDB
RGD		 PMID:11879205 SMP:00480 SMP:00481 SMP:00482, RGD:2317624 NCBI chr18:70,620,310...70,648,417
Ensembl chr18:68,345,012...68,373,249 		JBrowse link
G Acad9 acyl-CoA dehydrogenase family, member 9 ISO RGD PMID:14728676 RGD:2317589 NCBI chr 2:120,871,329...120,894,306
Ensembl chr 2:118,943,174...118,966,547 		JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain ISO
IDA		 SMPDB
RGD		 PMID:14728676 PMID:3968063 SMP:00480 SMP:00482, RGD:2317589, RGD:2317678 NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:68,333,980...68,372,220 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain ISO
IDA		 SMPDB
RGD		 PMID:14728676 PMID:3968063 SMP:00481, RGD:2317589, RGD:2317678 NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Acads acyl-CoA dehydrogenase short chain ISO
IDA		 SMPDB
RGD		 PMID:14728676 PMID:3968063 SMP:00480, RGD:2317589, RGD:2317678 NCBI chr12:47,154,259...47,163,580
Ensembl chr12:41,493,626...41,502,898 		JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain ISO
IMP		 RGD PMID:14728676 PMID:15850553 RGD:2317589, RGD:2317683 NCBI chr10:55,231,558...55,236,786
Ensembl chr10:54,732,469...54,738,075 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 ISO SMPDB SMP:00480 NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 ISO SMPDB
RGD		 PMID:17762044 SMP:00052 SMP:00482, RGD:2317576 NCBI chr16:52,487,870...52,554,110
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 ISO RGD PMID:17762044 RGD:2317576 NCBI chr 9:87,563,601...87,613,078
Ensembl chr 9:80,115,112...80,164,627 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 ISO RGD PMID:17762044 RGD:2317576 NCBI chr  X:110,739,633...110,803,416
Ensembl chr  X:105,942,799...106,006,427 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 ISO RGD PMID:17762044 RGD:2317576 NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:254,292,521...254,336,607 		JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 ISO RGD PMID:17762044 RGD:2317576 NCBI chr10:38,940,668...38,999,515
Ensembl chr10:38,440,080...38,498,757 		JBrowse link
G Acsm1 acyl-CoA synthetase medium-chain family member 1 ISO SMPDB SMP:00481 NCBI chr 1:183,417,052...183,451,897
Ensembl chr 1:173,984,672...174,025,495 		JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 ISO RGD PMID:17762044 RGD:2317576 NCBI chr 1:183,347,705...183,386,453
Ensembl chr 1:173,916,368...173,955,116 		JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 ISO RGD PMID:17762044 RGD:2317576 NCBI chr 1:183,564,652...183,591,328
Ensembl chr 1:174,133,288...174,160,184 		JBrowse link
G Acsm4 acyl-CoA synthetase medium-chain family member 4 ISO RGD PMID:17762044 RGD:2317576 NCBI chr 1:174,053,931...174,078,345
Ensembl chr 1:174,053,931...174,078,341 		JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 ISO RGD PMID:17762044 RGD:2317576 NCBI chr 3:159,910,809...159,960,748
Ensembl chr 3:139,450,383...139,500,325 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 ISO RGD PMID:17762044 RGD:2317576 NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:144,004,336...144,059,675 		JBrowse link
G Acss3 acyl-CoA synthetase short-chain family member 3 ISO SMPDB SMP:00480 NCBI chr 7:42,241,261...42,450,209
Ensembl chr 7:42,242,652...42,450,230 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A TAS
ISO		 SMPDB
RGD		 PMID:19430727 SMP:00482, RGD:2317584 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B ISO RGD PMID:19430727 RGD:2317584 NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:120,491,354...120,500,404 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 TAS
ISO		 SMPDB
RGD		 PMID:19430727 SMP:00052 SMP:00482, RGD:2317584 NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:122,664,677...122,682,095 		JBrowse link
G Crat carnitine O-acetyltransferase ISO SMPDB SMP:00052 NCBI chr 3:34,073,504...34,087,099
Ensembl chr 3:13,675,684...13,689,255 		JBrowse link
G Crot carnitine O-octanoyltransferase ISO SMPDB SMP:00052 NCBI chr 4:26,031,729...26,088,057
Ensembl chr 4:25,080,587...25,133,109 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 IMP
ISO		 SMPDB
RGD		 PMID:12379132 SMP:00480 SMP:00481 SMP:00482, RGD:2317616 NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Etfa electron transfer flavoprotein subunit alpha ISO RGD PMID:14728676 RGD:2317589 NCBI chr 8:64,731,192...64,787,965
Ensembl chr 8:55,835,134...55,891,969 		JBrowse link
G Etfb electron transfer flavoprotein subunit beta ISO RGD PMID:14728676 RGD:2317589 NCBI chr 1:102,988,499...103,002,663
Ensembl chr 1:93,851,858...93,866,068 		JBrowse link
G Etfdh electron transfer flavoprotein dehydrogenase ISO RGD PMID:14728676 RGD:2317589 NCBI chr 2:164,740,547...164,762,754
Ensembl chr 2:164,729,749...164,762,745 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase IMP
ISO		 SMPDB
RGD		 PMID:17491019 SMP:00480 SMP:00481 SMP:00482, RGD:2302227 NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:219,787,927...219,830,353 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha ISO SMPDB
RGD		 PMID:10816122 SMP:00481 SMP:00482, RGD:2317625 NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:26,187,956...26,227,869 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta ISO SMPDB
RGD		 PMID:10816122 SMP:00481 SMP:00482, RGD:2317625 NCBI chr 6:31,873,404...31,907,557
Ensembl chr 6:26,153,578...26,184,869 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 ISO SMPDB SMP:00480 NCBI chr  X:24,568,551...24,571,012
Ensembl chr  X:21,089,122...21,109,488 		JBrowse link
G Pex11g peroxisomal biogenesis factor 11 gamma ISO SMPDB SMP:00052 NCBI chr12:6,301,461...6,329,741
Ensembl chr12:1,503,646...1,512,585 		JBrowse link
G Pex13 peroxisomal biogenesis factor 13 ISO SMPDB SMP:00052 NCBI chr14:101,804,673...101,822,367
Ensembl chr14:97,603,539...97,621,262 		JBrowse link
G Pex14 peroxisomal biogenesis factor 14 ISO SMPDB SMP:00052 NCBI chr 5:164,682,876...164,819,352
Ensembl chr 5:159,399,776...159,536,272 		JBrowse link
G Slc25a20 solute carrier family 25 member 20 ISO SMPDB
RGD		 PMID:19430727 SMP:00052 SMP:00481 SMP:00482, RGD:2317584 NCBI chr 8:118,243,573...118,265,027
Ensembl chr 8:109,365,002...109,386,512 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1853
      lipid metabolic pathway 489
        fatty acid metabolic pathway 192
          fatty acid degradation pathway 42
            fatty acid beta degradation pathway 38
              very long-chain fatty acid beta degradation pathway 0
paths to the root