ONTOLOGY REPORT - ANNOTATIONS
Term: antiviral innate immune response
Accession: GO:0140374
browse the term
Definition: A defense response against viruses mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.
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Akap1
A-kinase anchoring protein 1
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:31522117) GO_REF:0000107
UniProt RGD Ensembl
PMID:31522117
GO_REF:0000024 GO_REF:0000107
NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896
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Atad3a
ATPase family, AAA domain containing 3A
involved_in
ISO ISS
(PMID:31522117) GO_REF:0000024
RGD UniProt
PMID:31522117
GO_REF:0000024
NCBI chr 5:166,350,302...166,370,492
Ensembl chr 5:166,350,304...166,370,482
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Clpb
ClpB family mitochondrial disaggregase
involved_in
ISO IEA
(PMID:31522117) GO_REF:0000107
RGD Ensembl
PMID:31522117
GO_REF:0000107
NCBI chr 1:156,028,740...156,158,183
Ensembl chr 1:156,028,930...156,168,788
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Cxcl10
C-X-C motif chemokine ligand 10
involved_in
IEA
GO_REF:0000107
Ensembl
GO_REF:0000107
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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Dhx15
DEAH-box helicase 15
involved_in
ISO
(PMID:24990078) (PMID:26494172), (PMID:34678144)
RGD
PMID:24990078 PMID:26494172 PMID:34678144
NCBI chr14:58,787,147...58,825,083
Ensembl chr14:58,787,127...58,825,088
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Dhx16
DEAH-box helicase 16
involved_in
ISO
(PMID:35263596)
RGD
PMID:35263596
NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948
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Dhx58
DEXH-box helicase 58
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525
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Dus2
dihydrouridine synthase 2
involved_in
ISO
UniProtKB:P19525 (PMID:18096616)
RGD
PMID:18096616
NCBI chr19:33,906,517...33,954,922
Ensembl chr19:33,911,750...33,954,709
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Eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
involved_in
IEA ISO
GO_REF:0000107 (PMID:22948139)
Ensembl RGD
PMID:22948139
GO_REF:0000107
NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
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Hcfc2
host cell factor C2
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:5445585 (PMID:28970238)
Ensembl RGD
PMID:28970238
GO_REF:0000107
NCBI chr 7:20,983,986...21,019,826
Ensembl chr 7:20,991,017...21,019,801
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Ifih1
interferon induced with helicase C domain 1
involved_in acts_upstream_of_or_within
IBA ISO
GO_REF:0000033 MGI:3663677 (PMID:28031478)
GO_Central RGD
PMID:28031478
GO_REF:0000033
NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456
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Ifit2
interferon-induced protein with tetratricopeptide repeats 2
involved_in acts_upstream_of_or_within
ISO
(PMID:19416887) (PMID:31390091)
RGD
PMID:19416887 PMID:31390091
NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635
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Ifit3
interferon-induced protein with tetratricopeptide repeats 3
involved_in
ISO
(PMID:21642987)
RGD
PMID:21642987
NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
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Irf3
interferon regulatory factor 3
involved_in
ISO
(PMID:9891032)
RGD
PMID:9891032
NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
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Marchf2
membrane associated ring-CH-type finger 2
involved_in
ISS ISO
GO_REF:0000024 (PMID:32935379)
UniProt RGD
PMID:32935379
GO_REF:0000024
NCBI chr 7:14,480,605...14,507,821
Ensembl chr 7:14,481,761...14,507,794
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Mavs
mitochondrial antiviral signaling protein
involved_in
ISO
(PMID:27992402)
RGD
PMID:27992402
NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
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Mbl2
mannose binding lectin 2
involved_in
ISO
(PMID:35102342)
RGD
PMID:35102342
NCBI chr 1:228,016,439...228,024,736
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Morc3
MORC family CW-type zinc finger 3
involved_in
ISO
(PMID:27440897)
RGD
PMID:27440897
NCBI chr11:33,151,906...33,194,650
Ensembl chr11:33,152,025...33,194,646
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Nck1
NCK adaptor protein 1
involved_in
ISO
(PMID:18835251)
RGD
PMID:18835251
NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300
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Nlrp1a
NLR family, pyrin domain containing 1A
involved_in
ISO
(PMID:33093214)
RGD
PMID:33093214
NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180
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Nlrp6
NLR family, pyrin domain containing 6
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:34161762) GO_REF:0000107 (PMID:26494172), (PMID:34678144)
UniProt RGD Ensembl
PMID:26494172 PMID:34161762 PMID:34678144
GO_REF:0000024 GO_REF:0000107
NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113
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Nmb
neuromedin B
involved_in
ISO
(PMID:31601264)
RGD
PMID:31601264
NCBI chr 1:134,869,446...134,875,507
Ensembl chr 1:134,869,446...134,872,190
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Nmbr
neuromedin B receptor
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:31601264) GO_REF:0000107
UniProt RGD Ensembl
PMID:31601264
GO_REF:0000024 GO_REF:0000107
NCBI chr 1:9,115,033...9,146,081
Ensembl chr 1:9,134,889...9,145,462
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Oas1a
2'-5' oligoadenylate synthetase 1A
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517
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Oas1b
2-5 oligoadenylate synthetase 1B
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr12:35,724,561...35,735,271
Ensembl chr12:35,724,055...35,735,242
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Oas1e
2'-5' oligoadenylate synthetase 1E
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr12:35,750,359...35,759,304
Ensembl chr12:35,750,359...35,759,301
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Oas1h
2 ' -5 ' oligoadenylate synthetase 1H
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr12:35,682,862...35,695,717
Ensembl chr12:35,683,699...35,693,366
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Oas1i
2 ' -5 ' oligoadenylate synthetase 1I
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr12:35,624,566...35,636,608
Ensembl chr12:35,624,592...35,636,604
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Oas2
2'-5' oligoadenylate synthetase 2
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371
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Oas3
2'-5'-oligoadenylate synthetase 3
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781
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Oasl
2'-5'-oligoadenylate synthetase-like
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641
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Oasl2
2'-5' oligoadenylate synthetase-like 2
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr12:41,710,072...41,722,687
Ensembl chr12:41,709,435...41,722,547
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Pde12
phosphodiesterase 12
involved_in
ISO IEA
(PMID:15231837) GO_REF:0000107
RGD Ensembl
PMID:15231837
GO_REF:0000107
NCBI chr16:1,920,062...1,925,638
Ensembl chr16:1,915,386...1,925,887
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Phb1
prohibitin 1
involved_in
ISO
(PMID:31522117)
RGD
PMID:31522117
NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
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Phb2
prohibitin 2
involved_in
ISO IEA
(PMID:31522117) GO_REF:0000107
RGD Ensembl
PMID:31522117
GO_REF:0000107
NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272
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Prkra
protein activator of interferon induced protein kinase EIF2AK2
involved_in
IEA ISO
GO_REF:0000107 (PMID:26454002)
Ensembl RGD
PMID:26454002
GO_REF:0000107
NCBI chr 3:61,575,447...61,594,393
Ensembl chr 3:61,575,447...61,594,347
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Rela
RELA proto-oncogene, NF-kB subunit
involved_in
ISO
(PMID:38114488)
RGD
PMID:38114488
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Rig1
RNA sensor RIG-1
involved_in
ISO
(PMID:28469175)
RGD
PMID:28469175
NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819
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Rnf135
ring finger protein 135
involved_in
ISO ISS
(PMID:28469175), (PMID:31006531) GO_REF:0000024 (PMID:21147464), (PMID:23950712)
RGD UniProt
PMID:21147464 PMID:23950712 PMID:28469175 PMID:31006531
GO_REF:0000024
NCBI chr10:65,170,560...65,189,791
Ensembl chr10:65,170,560...65,262,804
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Rpsa
ribosomal protein SA
involved_in
ISO
(PMID:38114488)
RGD
PMID:38114488
NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
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Senp7
SUMO specific peptidase 7
involved_in
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (PMID:28095500)
UniProt Ensembl RGD
PMID:28095500
GO_REF:0000024 GO_REF:0000107
NCBI chr11:44,423,733...44,584,129
Ensembl chr11:44,423,735...44,564,711
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Smarca5
SNF2 related chromatin remodeling ATPase 5
involved_in
ISO
(PMID:38114488)
RGD
PMID:38114488
NCBI chr19:27,271,918...27,304,594
Ensembl chr19:27,271,148...27,304,594
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Sting1
stimulator of interferon response cGAMP interactor 1
involved_in
ISO IEA
(PMID:21074459) GO_REF:0000107
RGD Ensembl
PMID:21074459
GO_REF:0000107
NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335
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Tbk1
TANK-binding kinase 1
involved_in
ISO
(PMID:14703513), (PMID:22394562)
RGD
PMID:14703513 PMID:22394562
NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
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Tmem120a
transmembrane protein 120A
involved_in
ISO
(PMID:35013224)
RGD
PMID:35013224
NCBI chr12:20,942,243...20,950,908
Ensembl chr12:20,942,439...20,990,316
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Tnf
tumor necrosis factor
involved_in
ISO
(PMID:11773383)
RGD
PMID:11773383
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Traf3ip3
TRAF3 interacting protein 3
acts_upstream_of_or_within
ISO
MGI:5795738 (PMID:31390091)
RGD
PMID:31390091
NCBI chr13:104,694,802...104,719,655
Ensembl chr13:104,694,805...104,719,673
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Traf6
TNF receptor associated factor 6
involved_in
ISO IEA
(PMID:18984593) GO_REF:0000107
RGD Ensembl
PMID:18984593
GO_REF:0000107
NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
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Trim25
tripartite motif-containing 25
involved_in
ISO
(PMID:17392790)
RGD
PMID:17392790
NCBI chr10:73,812,818...73,831,271
Ensembl chr10:73,812,818...73,831,257
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Trim31
tripartite motif-containing 31
involved_in
ISO
(PMID:27992402)
RGD
PMID:27992402
NCBI chr20:1,653,165...1,666,494
Ensembl chr20:1,653,165...1,666,494
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Trim6
tripartite motif containing 6
involved_in
ISO
(PMID:35263596)
RGD
PMID:35263596
NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914
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Trim65
tripartite motif-containing 65
acts_upstream_of_or_within
ISO
MGI:6356825|MGI:6356826|MGI:6356827 (PMID:28031478)
RGD
PMID:28031478
NCBI chr10:101,357,937...101,364,036
Ensembl chr10:101,357,937...101,364,971
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Trim7
tripartite motif-containing 7
involved_in
ISO
(PMID:35893676)
RGD
PMID:35893676
NCBI chr10:33,205,491...33,221,482
Ensembl chr10:33,205,491...33,221,468
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Uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
involved_in
ISO
(PMID:36603579)
RGD
PMID:36603579
NCBI chr13:82,342,946...82,377,558
Ensembl chr13:82,342,946...82,377,469
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Ube2n
ubiquitin-conjugating enzyme E2N
involved_in
ISO
(PMID:35893676)
RGD
PMID:35893676
NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
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Ube2w
ubiquitin-conjugating enzyme E2W
involved_in
ISO
(PMID:35893676)
RGD
PMID:35893676
NCBI chr 5:2,690,742...2,754,491
Ensembl chr 5:2,690,763...2,814,965
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Usp18
ubiquitin specific peptidase 18
involved_in
ISO
(PMID:27801882)
RGD
PMID:27801882
NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144
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Usp20
ubiquitin specific peptidase 20
involved_in
ISO
(PMID:27801882)
RGD
PMID:27801882
NCBI chr 3:14,272,737...14,306,409
Ensembl chr 3:14,272,908...14,306,409
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Usp44
ubiquitin specific peptidase 44
involved_in
ISO
(PMID:31968013)
RGD
PMID:31968013
NCBI chr 7:28,364,169...28,412,039
Ensembl chr 7:28,364,033...28,410,053
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Zbp1
Z-DNA binding protein 1
involved_in
ISO
(PMID:34192517)
RGD
PMID:34192517
NCBI chr 3:161,993,351...162,009,297
Ensembl chr 3:161,993,351...162,003,870
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Zdhhc1
zinc finger, DHHC-type containing 1
involved_in
ISO IBA
(PMID:25299331) GO_REF:0000033
RGD GO_Central
PMID:25299331
GO_REF:0000033
NCBI chr19:33,350,533...33,375,717
Ensembl chr19:33,350,533...33,375,616
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Zdhhc11
zinc finger, DHHC-type containing 11
involved_in
ISO IBA
(PMID:29429998) GO_REF:0000033
RGD GO_Central
PMID:29429998
GO_REF:0000033
NCBI chr 1:29,296,334...29,327,227
Ensembl chr 1:29,296,334...29,326,898
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