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ONTOLOGY REPORT - ANNOTATIONS

Term:SH3 domain binding
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Accession:GO:0017124 term browser browse the term
Definition:Binding to a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.


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SH3 domain binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI1 abl interactor 1 enables IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr10:48,939,407...49,069,269
Ensembl chr10:48,939,446...49,069,441 		JBrowse link
G ABI2 abl interactor 2 enables IBA GO_Central GO_REF:0000033 NCBI chr15:106,776,627...106,903,889
Ensembl chr15:106,776,631...106,900,333 		JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase enables IEA Ensembl GO_REF:0000107 NCBI chr 1:270,761,641...270,906,708
Ensembl chr 1:270,761,668...270,906,708 		JBrowse link
G ACP1 acid phosphatase 1 ISO RGD PMID:11971983 RGD:1625292 NCBI chr 3:132,671,408...132,684,793
Ensembl chr 3:132,667,045...132,684,674 		JBrowse link
G ADAM10 ADAM metallopeptidase domain 10 enables IEA UniProt GO_REF:0000043 NCBI chr 1:113,289,480...113,407,940
Ensembl chr 1:113,289,209...113,412,798 		JBrowse link
G ADAM12 ADAM metallopeptidase domain 12 enables ISO (PMID:15280379) BHF-UCL PMID:15280379 NCBI chr14:135,302,188...135,682,144
Ensembl chr14:135,302,813...135,682,159 		JBrowse link
G ADAM15 ADAM metallopeptidase domain 15 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:94,736,639...94,748,093
Ensembl chr 4:94,736,646...94,748,098 		JBrowse link
G ADAM19 ADAM metallopeptidase domain 19 enables ISO (PMID:12615925) UniProt PMID:12615925 NCBI chr16:65,715,445...65,814,761
Ensembl chr16:65,715,517...65,814,758 		JBrowse link
G ADAM9 ADAM metallopeptidase domain 9 enables IEA Ensembl GO_REF:0000107 NCBI chr15:47,523,768...47,601,722
Ensembl chr15:47,523,771...47,601,710 		JBrowse link
G AFAP1 actin filament associated protein 1 ISO RGD PMID:12114187 RGD:625602 NCBI chr 8:3,070,031...3,198,319
Ensembl chr 8:3,069,959...3,202,533 		JBrowse link
G AFAP1L2 actin filament associated protein 1 like 2 enables IEA Ensembl GO_REF:0000107 NCBI chr14:124,630,797...124,737,350
Ensembl chr14:124,630,799...124,672,813 		JBrowse link
G AKAP5 A-kinase anchoring protein 5 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:88,538,938...88,544,330
Ensembl chr 7:88,538,984...88,547,392 		JBrowse link
G ARHGAP27 Rho GTPase activating protein 27 enables ISO PMID:15147912 HGNC-UCL PMID:15147912 RGD:1302833 NCBI chr12:18,037,007...18,069,989
Ensembl chr12:18,037,138...18,082,348 		JBrowse link
G ARHGAP31 Rho GTPase activating protein 31 enables IEA Ensembl GO_REF:0000107 NCBI chr13:140,837,078...140,948,504
Ensembl chr13:140,839,268...140,948,303 		JBrowse link
G CASP9 caspase 9 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007 		JBrowse link
G CBL Cbl proto-oncogene enables ISO
IEA		 RGD
Ensembl		 PMID:9259313 PMID:17675467 GO_REF:0000107 RGD:11038829 RGD:11576315 NCBI chr 9:46,416,937...46,512,855
Ensembl chr 9:46,416,938...46,512,834 		JBrowse link
G CBLC Cbl proto-oncogene C enables IEA Ensembl GO_REF:0000107 NCBI chr 6:51,274,717...51,292,546
Ensembl chr 6:51,276,544...51,292,549 		JBrowse link
G CD2AP CD2 associated protein enables IEA Ensembl GO_REF:0000107 NCBI chr 7:42,218,016...42,332,523
Ensembl chr 7:42,218,290...42,332,518 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex enables IEA Ensembl GO_REF:0000107 NCBI chr 9:45,619,730...45,633,972
Ensembl chr 9:45,619,482...45,633,968 		JBrowse link
G CNTNAP1 contactin associated protein 1 ISO RGD PMID:9118959 RGD:70689 NCBI chr12:20,141,222...20,157,341
Ensembl chr12:20,141,641...20,157,044 		JBrowse link
G CRB3 crumbs cell polarity complex component 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:72,618,059...72,623,266
Ensembl chr 2:72,618,105...72,623,344 		JBrowse link
G CRK CRK proto-oncogene, adaptor protein enables IEA Ensembl GO_REF:0000107 NCBI chr12:47,656,805...47,685,641
Ensembl chr12:47,657,865...47,685,908 		JBrowse link
G CTTNBP2 cortactin binding protein 2 ISO RGD PMID:9813110 RGD:632437 NCBI chr18:28,130,213...28,573,166
Ensembl chr18:28,415,067...28,573,159 		JBrowse link
G CYBA cytochrome b-245 alpha chain enables IEA Ensembl GO_REF:0000107 NCBI chr 6:1,015,212...1,021,422
Ensembl chr 6:1,015,162...1,021,420 		JBrowse link
G DAB2IP DAB2 interacting protein enables IEA Ensembl GO_REF:0000107 NCBI chr 1:261,732,280...261,859,833
Ensembl chr 1:261,659,785...261,859,830 		JBrowse link
G DENND1A DENN domain containing 1A enables IEA Ensembl GO_REF:0000107 NCBI chr 1:264,300,989...264,823,351
Ensembl chr 1:264,300,994...264,823,489 		JBrowse link
G DNM1 dynamin 1 ISO RGD PMID:9348539 PMID:16648848 RGD:13504740 RGD:631926 NCBI chr 1:268,653,045...268,702,233
Ensembl chr 1:268,653,070...268,702,222 		JBrowse link
G DNM2 dynamin 2 enables ISO
IEA		 RGD
Ensembl		 PMID:19122684 GO_REF:0000107 RGD:9685149 NCBI chr 2:69,474,011...69,574,427
Ensembl chr 2:69,474,031...69,574,424 		JBrowse link
G DPYSL3 dihydropyrimidinase like 3 ISO RGD PMID:12684468 RGD:1298810 NCBI chr 2:148,663,563...148,777,055
Ensembl chr 2:148,662,051...148,776,619 		JBrowse link
G DRD4 dopamine receptor D4 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:398,766...401,539
Ensembl chr 2:398,766...402,433 		JBrowse link
G EFS embryonal Fyn-associated substrate enables IEA Ensembl GO_REF:0000107 NCBI chr 7:75,720,033...75,731,615
Ensembl chr 7:75,722,183...75,731,610 		JBrowse link
G ELMO1 engulfment and cell motility 1 enables IEA UniProt
Ensembl		 GO_REF:0000043 GO_REF:0000107 NCBI chr18:36,755,026...37,336,095
Ensembl chr18:36,786,378...37,347,283 		JBrowse link
G ELMO2 engulfment and cell motility 2 enables IEA UniProt GO_REF:0000043 NCBI chr17:48,526,692...48,567,665
Ensembl chr17:48,526,700...48,567,657 		JBrowse link
G ELMO3 engulfment and cell motility 3 enables IEA UniProt GO_REF:0000043 NCBI chr 6:27,841,559...27,846,332
Ensembl chr 6:27,841,624...27,846,330 		JBrowse link
G ENAH ENAH actin regulator enables IEA UniProt GO_REF:0000043 NCBI chr10:13,439,772...13,609,347
Ensembl chr10:13,446,426...13,609,303 		JBrowse link
G ENKUR enkurin, TRPC channel interacting protein enables IEA UniProt GO_REF:0000043 NCBI chr10:50,310,497...50,364,311
Ensembl chr10:50,310,984...50,341,238 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 ISO RGD PMID:11003669 RGD:9685556 NCBI chr 6:68,667,651...68,682,629
Ensembl chr 6:68,669,153...68,682,623 		JBrowse link
G ESPN espin enables ISO PMID:12598619 UniProt PMID:12598619 RGD:632657 NCBI chr 6:67,284,106...67,316,577
Ensembl chr 6:67,284,079...67,316,591 		JBrowse link
G EVL Enah/Vasp-like enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr 7:120,911,814...121,056,556
Ensembl chr 7:120,911,648...121,056,555 		JBrowse link
G FMN1 formin 1 enables ISO (PMID:8438166) MGI PMID:8438166 NCBI chr 1:136,696,353...137,163,532
Ensembl chr 1:136,704,090...137,163,537 		JBrowse link
G FUT8 fucosyltransferase 8 enables IEA UniProt GO_REF:0000043 NCBI chr 7:89,395,637...89,680,502
Ensembl chr 7:89,519,730...89,680,489 		JBrowse link
G GJA1 gap junction protein alpha 1 enables ISO dependent on acidic pH
PMID:14699011
PMID:15492000		 RGD
CAFA
DisProt		 PMID:14699011 PMID:15492000 RGD:12793032 RGD:1582694 NCBI chr 1:40,988,818...41,002,129
Ensembl chr 1:40,988,528...41,002,156 		JBrowse link
G GPX1 glutathione peroxidase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433 		JBrowse link
G GRB2 growth factor receptor bound protein 2 enables IEA Ensembl GO_REF:0000107 NCBI chr12:5,940,723...6,009,095
Ensembl chr12:5,940,647...6,010,835 		JBrowse link
G GRIK5 glutamate ionotropic receptor kainate type subunit 5 enables ISO PMID:1127911 UniProt PMID:1127911 RGD:8553546 NCBI chr 6:49,840,671...49,901,656
Ensembl chr 6:49,845,656...49,902,080 		JBrowse link
G HCLS1 hematopoietic cell-specific Lyn substrate 1 enables IEA Ensembl GO_REF:0000107 NCBI chr13:138,852,387...138,883,088
Ensembl chr13:138,855,144...138,889,281 		JBrowse link
G HIP1R huntingtin interacting protein 1 related enables IEA Ensembl GO_REF:0000107 NCBI chr14:29,996,388...30,024,343
Ensembl chr14:29,993,655...30,024,216 		JBrowse link
G ILK integrin linked kinase ISO SH3 domain of c-src (unknown species) RGD PMID:18252715 RGD:2301742 NCBI chr 9:3,145,647...3,152,097
Ensembl chr 9:3,145,608...3,159,858 		JBrowse link
G INPPL1 inositol polyphosphate phosphatase like 1 enables IEA UniProt GO_REF:0000043 NCBI chr 9:6,793,971...6,807,286
Ensembl chr 9:6,793,069...6,808,028 		JBrowse link
G ITGB1BP2 integrin subunit beta 1 binding protein 2 enables IEA UniProt GO_REF:0000043 NCBI chr  X:57,316,490...57,321,614
Ensembl chr  X:57,316,471...57,325,096 		JBrowse link
G KHDRBS1 KH RNA binding domain containing, signal transduction associated 1 enables ISO
IEA		 RGD
UniProt
Ensembl		 PMID:12112020 GO_REF:0000043 GO_REF:0000107 RGD:634064 NCBI chr 6:88,530,364...88,572,467
Ensembl chr 6:88,530,385...88,572,463 		JBrowse link
G KHDRBS2 KH RNA binding domain containing, signal transduction associated 2 enables IEA UniProt GO_REF:0000043 NCBI chr 7:27,348,614...27,895,572
Ensembl chr 7:27,390,918...27,895,597 		JBrowse link
G KHDRBS3 KH RNA binding domain containing, signal transduction associated 3 enables IEA UniProt GO_REF:0000043 NCBI chr 4:6,289,577...6,446,494
Ensembl chr 4:6,282,076...6,446,389 		JBrowse link
G LANCL1 LanC like glutathione S-transferase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr15:113,111,427...113,149,181
Ensembl chr15:113,111,370...113,149,050 		JBrowse link
G LOC100621521 ABI gene family member 3 enables IBA GO_Central GO_REF:0000033 NCBI chr12:25,426,116...25,441,309 JBrowse link
G LOC110255205 ABI gene family member 3-like enables IBA GO_Central GO_REF:0000033 NCBI chr12:25,322,040...25,336,099 JBrowse link
G LRP2 LDL receptor related protein 2 enables IEA UniProt GO_REF:0000043 NCBI chr15:75,565,299...75,754,604
Ensembl chr15:75,565,303...75,716,694 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase enables IEA Ensembl GO_REF:0000107 NCBI chr 4:75,793,273...75,903,710
Ensembl chr 4:75,793,492...75,903,496 		JBrowse link
G MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 ISO RGD PMID:11384986 RGD:727317 NCBI chr 3:100,887,148...101,084,667
Ensembl chr 3:100,887,143...101,084,677 		JBrowse link
G MAPT microtubule associated protein tau enables ISO (PMID:9763511) UniProt PMID:9763511 NCBI chr12:17,098,259...17,211,483
Ensembl chr12:17,095,587...17,211,373 		JBrowse link
G MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:75,511,692...75,522,760
Ensembl chr 1:75,511,693...75,522,765 		JBrowse link
G MVB12A multivesicular body subunit 12A enables IEA UniProt GO_REF:0000043 NCBI chr 2:60,271,020...60,275,972
Ensembl chr 2:60,271,026...60,275,971 		JBrowse link
G MYPN myopalladin enables IEA Ensembl GO_REF:0000107 NCBI chr14:71,283,271...71,388,591
Ensembl chr14:71,299,505...71,387,025 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 3:11,820,367...11,834,394
Ensembl chr 3:11,820,266...11,839,354 		JBrowse link
G NOXA1 NADPH oxidase activator 1 enables IEA Ensembl GO_REF:0000107
G OSTF1 osteoclast stimulating factor 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:228,142,159...228,196,808
Ensembl chr 1:228,142,041...228,197,035 		JBrowse link
G PDCD6IP programmed cell death 6 interacting protein ISO RGD PMID:10858458 RGD:68284 NCBI chr13:19,597,064...19,664,047
Ensembl chr13:19,597,059...19,665,996 		JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein ISO RGD PMID:10926122 RGD:1600757 NCBI chr 9:19,835,934...19,947,239
Ensembl chr 9:19,835,938...20,123,566 		JBrowse link
G PLSCR1 phospholipid scramblase 1 enables ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr13:86,836,288...86,869,569
Ensembl chr13:86,834,587...86,869,297 		JBrowse link
G PRKCE protein kinase C epsilon ISO RGD PMID:17084383 RGD:2326120 NCBI chr 3:94,351,277...94,864,549
Ensembl chr 3:94,349,889...94,866,306 		JBrowse link
G PRRT2 proline rich transmembrane protein 2 enables ISO PMID:26797119 MGI PMID:26797119 RGD:11528976 NCBI chr 3:18,048,614...18,052,481
Ensembl chr 3:18,048,618...18,052,480 		JBrowse link
G PTPN12 protein tyrosine phosphatase non-receptor type 12 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:102,480,914...102,563,969
Ensembl chr 9:102,480,924...102,563,751 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:63,762,109...63,779,086
Ensembl chr 5:63,762,112...63,808,350 		JBrowse link
G PTTG1 PTTG1 regulator of sister chromatid separation, securin enables IEA UniProt GO_REF:0000043 NCBI chr16:63,104,698...63,112,382 JBrowse link
G QKI QKI, KH domain containing RNA binding enables IEA UniProt GO_REF:0000043 NCBI chr 1:4,732,575...4,883,386
Ensembl chr 1:4,735,514...4,883,392 		JBrowse link
G RAD9A RAD9 checkpoint clamp component A enables IEA Ensembl GO_REF:0000107 NCBI chr 2:5,123,142...5,129,740
Ensembl chr 2:5,123,134...5,129,703 		JBrowse link
G REPS1 RALBP1 associated Eps domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:25,481,283...25,565,284
Ensembl chr 1:25,481,343...25,565,277 		JBrowse link
G RIMS1 regulating synaptic membrane exocytosis 1 ISO RGD PMID:10748113 RGD:633421 NCBI chr 1:51,785,140...52,246,456
Ensembl chr 1:51,785,495...52,244,934 		JBrowse link
G RUFY1 RUN and FYVE domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:78,974,361...79,021,677
Ensembl chr 2:78,963,989...79,021,574 		JBrowse link
G RUFY2 RUN and FYVE domain containing 2 enables IEA Ensembl GO_REF:0000107 NCBI chr14:71,497,232...71,547,737
Ensembl chr14:71,498,651...71,547,311 		JBrowse link
G SGIP1 SH3GL interacting endocytic adaptor 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:145,815,658...146,051,621
Ensembl chr 6:145,822,269...146,052,526 		JBrowse link
G SH3BGRL SH3 domain binding glutamate rich protein like enables IEA UniProt GO_REF:0000043 NCBI chr  X:64,617,350...64,709,006 JBrowse link
G SH3BGRL2 SH3 domain binding glutamate rich protein like 2 enables IEA UniProt GO_REF:0000043 NCBI chr 1:86,416,281...86,481,805
Ensembl chr 1:86,358,483...86,481,776 		JBrowse link
G SH3BP1 SH3 domain binding protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:10,172,303...10,187,883
Ensembl chr 5:10,172,667...10,187,906 		JBrowse link
G SH3BP2 SH3 domain binding protein 2 enables ISO (PMID:8438166) MGI PMID:8438166 NCBI chr 8:1,583,169...1,619,038
Ensembl chr 8:1,583,193...1,619,037 		JBrowse link
G SH3BP5 SH3 domain binding protein 5 enables IEA UniProt GO_REF:0000104 NCBI chr13:2,504,282...2,585,601
Ensembl chr13:2,506,156...2,585,526 		JBrowse link
G SH3BP5L SH3 binding domain protein 5 like enables IEA UniProt GO_REF:0000104 NCBI chr 2:52,323,009...52,337,198
Ensembl chr 2:52,323,048...52,339,665 		JBrowse link
G SH3GL1 SH3 domain containing GRB2 like 1, endophilin A2 ISO RGD PMID:22750032 RGD:13463484 NCBI chr 2:74,414,453...74,445,450
Ensembl chr 2:74,414,466...74,445,447 		JBrowse link
G SHANK1 SH3 and multiple ankyrin repeat domains 1 enables ISO PMID:15496675 BHF-UCL PMID:15496675 RGD:8553458 NCBI chr 6:55,452,095...55,496,304
Ensembl chr 6:55,451,094...55,499,031 		JBrowse link
G SHANK2 SH3 and multiple ankyrin repeat domains 2 ISO RGD PMID:15014124 RGD:1599734 NCBI chr 2:2,517,853...3,016,959
Ensembl chr 2:2,864,331...3,015,314 		JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 ISO RGD PMID:15014124 RGD:1599734 NCBI chr 5:41,376...93,033
Ensembl chr 5:41,786...93,177 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO RGD PMID:10913276 RGD:1581107 NCBI chr 3:101,209,568...101,366,057
Ensembl chr 3:101,209,641...101,362,723 		JBrowse link
G SYNJ1 synaptojanin 1 ISO also binds SH3 domain of endophilins RGD PMID:8552192 PMID:11498538 PMID:17097615 RGD:13513210 RGD:628465 RGD:69388 NCBI chr13:196,230,101...196,330,512
Ensembl chr13:196,230,104...196,330,384 		JBrowse link
G SYNJ2 synaptojanin 2 ISO also binds SH3 domain of endophilins RGD PMID:11498538 RGD:628465 NCBI chr 1:9,014,206...9,109,050
Ensembl chr 1:9,014,551...9,109,103 		JBrowse link
G UVRAG UV radiation resistance associated enables IEA Ensembl GO_REF:0000107 NCBI chr 9:10,088,779...10,370,857
Ensembl chr 9:10,088,798...10,370,855 		JBrowse link
G VASP vasodilator stimulated phosphoprotein enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr 6:51,872,810...51,886,729
Ensembl chr 6:51,872,812...51,886,724 		JBrowse link
G WAS WASP actin nucleation promoting factor enables IEA Ensembl GO_REF:0000107 NCBI chr  X:42,774,597...42,793,055
Ensembl chr  X:42,774,588...42,793,055 		JBrowse link
G WASF2 WASP family member 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:84,621,742...84,697,428
Ensembl chr 6:84,622,800...84,697,429 		JBrowse link
G WIPF1 WAS/WASL interacting protein family member 1 enables ISO (PMID:19798448) UniProt PMID:19798448 NCBI chr15:80,521,032...80,646,462 JBrowse link
G WIPF3 WAS/WASL interacting protein family member 3 ISO RGD PMID:8906616 RGD:1302419 NCBI chr18:42,991,495...43,025,177
Ensembl chr18:42,991,498...43,071,331 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon enables IEA Ensembl GO_REF:0000107 NCBI chr12:47,601,133...47,645,327
Ensembl chr12:47,600,745...47,645,301 		JBrowse link
G ZNF106 zinc finger protein 106 enables ISO (PMID:9507006) MGI PMID:9507006 NCBI chr 1:128,893,965...128,957,334
Ensembl chr 1:128,893,971...128,957,305 		JBrowse link
G ZNF384 zinc finger protein 384 ISO RGD PMID:10669742 RGD:1299381 NCBI chr 5:64,003,468...64,025,798
Ensembl chr 5:64,003,216...64,025,796 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18634
    binding 16167
      protein binding 14325
        protein domain specific binding 785
          SH3 domain binding 104
paths to the root