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Gene: PLSCR1 (phospholipid scramblase 1) Sus scrofa

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Symbol:

PLSCR1

Name:

phospholipid scramblase 1

RGD ID:

14060245

Description:

ENCODES a protein that exhibits calcium ion binding (ortholog); CD4 receptor binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN acute-phase response (ortholog); apoptotic process (ortholog); cellular response to cytokine stimulus (ortholog); ASSOCIATED WITH COVID-19 (ortholog); Experimental Liver Cirrhosis (ortholog); Human Influenza (ortholog); FOUND IN cytosol (ortholog); Golgi apparatus (ortholog); membrane raft (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	86,834,587 - 86,869,297 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	86,836,288 - 86,869,569 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

Experimental Liver Cirrhosis (ISO)

Human Influenza (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acute-phase response (ISO)

apoptotic process (IEA,ISS)

cellular response to cytokine stimulus (ISO)

cellular response to lipopolysaccharide (ISO)

defense response to virus (IEA,ISS)

immune response (ISO)

intrinsic apoptotic signaling pathway (ISO)

myeloid cell differentiation (ISO)

negative regulation of phagocytosis (IEA)

negative regulation of viral genome replication (IEA,ISS)

phosphatidylserine biosynthetic process (ISO)

phosphatidylserine exposure on apoptotic cell surface (IEA,ISO)

plasma membrane phospholipid scrambling (IBA,IEA,ISS)

positive regulation of apoptotic process (ISO)

positive regulation of chromosome separation (IEA)

positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity (ISS)

positive regulation of gene expression (IEA)

positive regulation of innate immune response (IEA,ISS)

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage (ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISS)

regulation of Fc receptor mediated stimulatory signaling pathway (ISS)

regulation of mast cell activation (ISS)

response to interferon-alpha (ISO)

response to interferon-beta (IEA)

response to lead ion (IEA)

symbiont entry into host cell (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IEA,ISS)

Golgi apparatus (IEA,ISS)

membrane (IEA)

membrane raft (IEA,ISS)

nucleolus (IEA,ISO,ISS)

nucleoplasm (IEA)

nucleus (IEA)

perinuclear region of cytoplasm (IEA)

plasma membrane (IBA,IEA,ISS)

Molecular Function

calcium ion binding (IEA,ISS)

CD4 receptor binding (IEA,ISS)

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA,ISS)

enzyme binding (IEA)

epidermal growth factor receptor binding (IEA,ISS)

lead ion binding (IEA)

magnesium ion binding (IEA)

mercury ion binding (IEA)

nuclease activity (IEA)

phospholipid scramblase activity (IBA,IEA,ISS)

protein binding (ISO)

SH3 domain binding (IEA,ISS)

virus receptor activity (IEA)

zinc ion binding (IEA)

References

Additional References at PubMed

PMID:15679890	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

PLSCR1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	86,834,587 - 86,869,297 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	86,836,288 - 86,869,569 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

PLSCR1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	146,515,180 - 146,544,607 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	146,511,858 - 146,544,862 (-)	Ensembl			hg38	GRCh38
GRCh37	3	146,232,967 - 146,262,394 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	147,715,658 - 147,745,186 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	147,715,665 - 147,745,194	NCBI
Celera	3	144,649,990 - 144,679,651 (-)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI
HuRef	3	143,609,792 - 143,639,453 (-)	NCBI		HuRef
CHM1_1	3	146,196,031 - 146,225,691 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	149,270,345 - 149,299,772 (-)	NCBI		T2T-CHM13v2.0

Plscr1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	92,132,265 - 92,154,034 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	92,131,803 - 92,154,331 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	92,250,194 - 92,272,561 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	92,249,750 - 92,272,278 (+)	Ensembl			mm10	GRCm38
MGSCv37	9	92,145,032 - 92,167,399 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	92,063,114 - 92,075,746 (+)	NCBI		MGSCv36	mm8
Celera	9	91,837,716 - 91,860,050 (+)	NCBI		Celera
Cytogenetic Map	9	E3.3	NCBI
cM Map	9	48.35	NCBI

Plscr1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	101,662,512 - 101,684,474 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	101,664,056 - 101,684,614 (+)	Ensembl				GRCr8
mRatBN7.2	8	92,784,279 - 92,804,698 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	92,784,356 - 92,804,692 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	98,462,546 - 98,482,894 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	96,661,795 - 96,682,143 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	94,494,749 - 94,515,160 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	99,625,523 - 99,645,882 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	99,625,545 - 99,725,217 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	99,108,895 - 99,129,251 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	97,206,388 - 97,226,725 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	92,307,776 - 92,328,258 (+)	NCBI		Celera
RGSC_v3.1	8	97,225,842 - 97,246,179 (+)	NCBI
Cytogenetic Map	8	q31	NCBI

Plscr1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955474	10,953,033 - 10,990,712 (+)	Ensembl
ChiLan1.0	NW_004955474	10,953,381 - 10,989,100 (+)	NCBI	ChiLan1.0	ChiLan1.0

PLSCR1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	144,397,437 - 144,426,848 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	144,402,168 - 144,431,880 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	143,528,967 - 143,558,468 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	151,111,622 - 151,141,264 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	151,112,483 - 151,132,964 (-)	Ensembl			panPan2	panpan1.1

PLSCR1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	41,639,938 - 41,668,972 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	41,599,843 - 41,669,112 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	41,505,247 - 41,534,148 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	42,258,129 - 42,287,174 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	42,258,522 - 42,287,370 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	41,846,168 - 41,875,156 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	41,921,170 - 41,950,076 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	42,164,670 - 42,193,494 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Plscr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	80,943,177 - 80,974,329 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936519	8,759,627 - 8,790,830 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936519	8,759,702 - 8,790,823 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PLSCR1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	44,160,017 - 44,189,056 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	44,160,200 - 44,188,195 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	17,044,147 - 17,072,858 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in PLSCR1
344 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
10	4	23	3	2	5	14	12	23	3	6	3

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001246213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021068460	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021068461	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY609797	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01014007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HQ266639	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000031489 ⟹ ENSSSCP00000023245

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	13	86,834,587 - 86,859,915 (-)	Ensembl

Ensembl Acc Id:

ENSSSCT00000048400 ⟹ ENSSSCP00000035245

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	13	86,834,587 - 86,868,969 (-)	Ensembl

Ensembl Acc Id:

ENSSSCT00000049433 ⟹ ENSSSCP00000043258

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	13	86,836,293 - 86,869,297 (-)	Ensembl

Ensembl Acc Id:

ENSSSCT00000069560 ⟹ ENSSSCP00000067911

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	13	86,836,293 - 86,869,297 (-)	Ensembl

Ensembl Acc Id:

ENSSSCT00000074603 ⟹ ENSSSCP00000069539

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	13	86,836,291 - 86,860,081 (-)	Ensembl

RefSeq Acc Id:

NM_001246213 ⟹ NP_001233142

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	13	86,837,218 - 86,859,919 (-)	NCBI

Sequence:

show sequence

ATGAAGGCTCCTTATCCGGGAACACACTCACCAGCTCAGAATCCCCCTGAATATCCTTCAGCAG
GATTCTCAGGACCTCCAGGATATACTGGCCACCCTGCCCCTCAGGCTGGCTACCCCATCCCACC
AGCTGGCTACCCAGCCCCCCAGGCTAGCTATCCAGGTGTTGGTCCAGTGGGCTTTCCTGGCCAA
CACCAGCCAGTGTCTCATCAGTCAGGTGCCCCTGCAGGAATACCATGGATGCCGGCACCACCAC
CTCCAGCAAACTGTCCACCTGGATTGGAGTATTTAACTCAGATAGATCAACTATTGATTCATCA
GCAAATTGAACTTCTGGAAGTCTTAACAGGCTTTGAAACTAATAACAAATATGAAATCAAGAAC
AGCCTTGGACAGAGGATTTACTTTGCAGCAGAGGACACTGATTGCTGTACTAGAAACTGCTGTG
GGCCTTCTAGGCCTTTCACCATGAGAATTCTTGATAATATGGGCCGAGAAGTCATAACTCTGGA
GAGACCACTAAGATGTACCAGCTGTTGTTTCCCCTGCTGCCTGCAAGAGATAGAAATCCAAGCT
CCTCCTGGCATACCAGTAGGTTATGTTACTCAAACCTGGCACCCATGCTTGCCAAGGTTTACAG
TTCAAAATGAGAGGCGAGAAGACGTACTAAAAATTACTGGTCCATGTGTTGTCTGCAGCTGTTG
TGCAGATATTGATTTTGAGATTAAATCTCTTGATGATAAATACGTGGTTGGCAAGATTTCAAAG
CAGTGGTCTGGCTTAGTGAGAGAGATGTTTACAGATGTTGATAACTTTGGCATCCAGTTCCCTT
TAGACCTTGATGTGAAAATGAAAGCTGTGATGCTTGGTGCATGTTTCCTCATTGACTTCATGTT
TTTTGAAATGACCAGAGGTGAACAGAGATCAGGAGTGTGGTAG

hide sequence

RefSeq Acc Id:

XM_021068460 ⟹ XP_020924119

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	13	86,836,288 - 86,869,569 (-)	NCBI

Sequence:

show sequence

CTGTTTGCCAGTAGGGGCGCCAGAAATAGTAAACAATTTAAATACATCTAATGAACAGGATTCT
TCAATCATCCGGGTGAAATGAGAGAGAGAGAGCAAGACAATGAAAAAGAAAAGGCACCATAAAG
AAAAGAAAGCTTGACTCATCTTCATTTGTACTCTTTACCGCCTCCTCTTTCCCGGTTCCAAAGC
AACGGGACTCTCAATGACCAAGGACAAAGCCAGGATAAAGGAAATTCTCCAGAGCTAGACCCAT
AGTCCACCCCAGAGGCAGCCACTCCCCGGCTAATGACTTTACGAGTCCCAACTGGTTTCGACGT
CTCACTTCCTCGAGATCCTGAACCTCAGAACCAACATTTAGGAGACGCTTAGGAGGCAAGCAGG
GCGGAGGGGATCCTCTCCACGCCGCGCGGGGCAGCGGTCTCACCTCCAGGTCCCGAGCCCTCCA
GAGGGGACGCGGAAGCGGAAGCGCCAGCGCGGGGACGAGGGCGGGAGGCCTTTTGTAGCCTAGC
ATCTAGGAAACGAAACCAAATCAGGTTTCGACACTGAGGTCGCTCGGGAACCTAACTGGTTACT
TCAGGGAAGGTTGTGTAACAGGCGCATTTGACCGCCGAGGGCCAGAGGAAGCAGAGCATCAGAT
CAGCGCTTGGGTTCCCAGAGCTGGTCTCCTCTCAGGGGGACGCGGGTGCCCCGGGGGCTACAGA
ACTGTTTAAACCATGGACAACCAAAATGCGCAAATGAAGGCTCCTTATCCGGGAACACACTCAC
CAGCTCAGAATCCCCCTGAATATCCTTCAGCAGGATTCTCAGGACCTCCAGGATATACTGGCCA
CCCTGCCCCTCAGGCTGGCTACCCCATCCCACCAGCTGGCTACCCAGCCCCCCAGGCTAGCTAT
CCAGGTGTTGGTCCAGTGGGCTTTCCTGGCCAACACCAGCCAGTGTCTCATCAGTCAGGTGCCC
CTGCAGGAATACCATGGATGCCGGCACCACCACCTCCAGCAAACTGTCCACCTGGATTGGAGTA
TTTAACTCAGATAGATCAACTATTGATTCATCAGCAAATTGAACTTCTGGAAGTCTTAACAGGC
TTTGAAACTAATAACAAATATGAAATCAAGAACAGCCTTGGACAGAGGATTTACTTTGCAGCAG
AGGACACTGATTGCTGTACTAGAAACTGCTGTGGGCCTTCTAGGCCTTTCACCATGAGAATTCT
TGATAATATGGGCCGAGAAGTCATAACTCTGGAGAGACCACTAAGATGTACCAGCTGTTGTTTC
CCCTGCTGCCTGCAAGAGATAGAAATCCAAGCTCCTCCTGGCATACCAGTAGGTTATGTTACTC
AAACCTGGCACCCATGCTTGCCAAGGTTTACAGTTCAAAATGAGAGGCGAGAAGACGTACTAAA
AATTACTGGTCCATGTGTTGTCTGCAGCTGTTGTGCAGATATTGATTTTGAGATTAAATCTCTT
GATGATAAATACGTGGTTGGCAAGATTTCAAAGCAGTGGTCTGGCTTAGTGAGAGAGATGTTTA
CAGATGTTGATAACTTTGGCATCCAGTTCCCTTTAGACCTTGATGTGAAAATGAAAGCTGTGAT
GCTTGGTGCATGTTTCCTCATTGACTTCATGTTTTTTGAAATGACCAGAGGTGAACAGAGATCA
GGAGTGTGGTAGTTCATTAAATGAAAGTCTCAGAAAACCTTAAGTTTATATATTGATTGGGAAT
ACATAAAAGAAAGACCCTGGATTCTTTTCTTTATTGAAATGATTTATCATAGCATGTGTGAATT
ACACTGTCATGCCTGAAGCTCCAGGTATATGATTTTACTTTTCAAATTAAGAATTTTCTATATC
ACTTACTTATGTTTTTATACATTTTCTTTTATACATTTAATTGTATACTTTTTTCATTGTGTAT
TTCAGAGAAAAAATATAGATGTTTTTACATTTAAATGTAACTTCCTGTGATGAACTGCTGTGAG
CTACAGTCTCTATTTTCAATTTCTATAGCAAAATTAAAGCCTTTTAAAGTAAATTTAATATAAA
TTTATGCACTATTTTATTAGATCTAGTTCATTTCATATGTAACAACAAATGTTATTTTGCAAGT
ACTGTATATTCAAAACCGTTCAAAACAAACATAATTTCTTTCCAATTATGTTCTTTATAGTTAT
GTTCAAATGATACTCAGTATTCATATTATCAAGGAAAAGTAAAATGTACTTGTTTTTTGTTTGG
AAAATCACACTATATTTAACTTCACCTATAAGCTAAATTGCGAGCATAAATAACGTTATATTGA
CAAAACTACAAATTAATAATTTTCATGATTTTTCATGAAAAAAGGATGATTCTATCCCAAAGAA
GGAAACTTTTAAAGACTCCCTGTAAAACTAGATATTGTTATAATTTTTGAAGTAATTATTTACA
CATGGAATGGCTGACTACTGTATTTTATCATTCATGGAATATGATAGTTATCAGATTACTCAGG
TGTTAGTTAAATAGACTATATATATTCTGTCTCAGAATAAATGTCTATAATGCTCTAATAGATT
ATTTTTAACAACAATCAAATAACTAAAATAAAAAATTGCTGATATA

hide sequence

RefSeq Acc Id:

XM_021068461 ⟹ XP_020924120

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	13	86,836,295 - 86,868,705 (-)	NCBI

Sequence:

show sequence

AACTGAGTCTGTACCCCTCCAGGGGGCCGGCTGACCCAGCCTTACTCTGGCCAGCCCAGGACCT
TTTCAAAGCCAAAGAGTTTCTTGCTTGAAAACACTTTGTAGGTGTGGCTTCCTTAGTACATCTG
TTCACAGCGCAGAGAGCTGAGCCGGATCATGGCCAGAACCTGGGCTCAGGGGTCTCTGCCAGCA
TTTGGGGGTATCAGAATGGATGATTAATAGAGTTTACTGGCTGTCATTGAACAAACTGTTTAAA
CCATGGACAACCAAAATGCGCAAATGAAGGCTCCTTATCCGGGAACACACTCACCAGCTCAGAA
TCCCCCTGAATATCCTTCAGCAGGATTCTCAGGACCTCCAGGATATACTGGCCACCCTGCCCCT
CAGGCTGGCTACCCCATCCCACCAGCTGGCTACCCAGCCCCCCAGGCTAGCTATCCAGGTGTTG
GTCCAGTGGGCTTTCCTGGCCAACACCAGCCAGTGTCTCATCAGTCAGGTGCCCCTGCAGGAAT
ACCATGGATGCCGGCACCACCACCTCCAGCAAACTGTCCACCTGGATTGGAGTATTTAACTCAG
ATAGATCAACTATTGATTCATCAGCAAATTGAACTTCTGGAAGTCTTAACAGGCTTTGAAACTA
ATAACAAATATGAAATCAAGAACAGCCTTGGACAGAGGATTTACTTTGCAGCAGAGGACACTGA
TTGCTGTACTAGAAACTGCTGTGGGCCTTCTAGGCCTTTCACCATGAGAATTCTTGATAATATG
GGCCGAGAAGTCATAACTCTGGAGAGACCACTAAGATGTACCAGCTGTTGTTTCCCCTGCTGCC
TGCAAGAGATAGAAATCCAAGCTCCTCCTGGCATACCAGTAGGTTATGTTACTCAAACCTGGCA
CCCATGCTTGCCAAGGTTTACAGTTCAAAATGAGAGGCGAGAAGACGTACTAAAAATTACTGGT
CCATGTGTTGTCTGCAGCTGTTGTGCAGATATTGATTTTGAGATTAAATCTCTTGATGATAAAT
ACGTGGTTGGCAAGATTTCAAAGCAGTGGTCTGGCTTAGTGAGAGAGATGTTTACAGATGTTGA
TAACTTTGGCATCCAGTTCCCTTTAGACCTTGATGTGAAAATGAAAGCTGTGATGCTTGGTGCA
TGTTTCCTCATTGACTTCATGTTTTTTGAAATGACCAGAGGTGAACAGAGATCAGGAGTGTGGT
AGTTCATTAAATGAAAGTCTCAGAAAACCTTAAGTTTATATATTGATTGGGAATACATAAAAGA
AAGACCCTGGATTCTTTTCTTTATTGAAATGATTTATCATAGCATGTGTGAATTACACTGTCAT
GCCTGAAGCTCCAGGTATATGATTTTACTTTTCAAATTAAGAATTTTCTATATCACTTACTTAT
GTTTTTATACATTTTCTTTTATACATTTAATTGTATACTTTTTTCATTGTGTATTTCAGAGAAA
AAATATAGATGTTTTTACATTTAAATGTAACTTCCTGTGATGAACTGCTGTGAGCTACAGTCTC
TATTTTCAATTTCTATAGCAAAATTAAAGCCTTTTAAAGTAAATTTAATATAAATTTATGCACT
ATTTTATTAGATCTAGTTCATTTCATATGTAACAACAAATGTTATTTTGCAAGTACTGTATATT
CAAAACCGTTCAAAACAAACATAATTTCTTTCCAATTATGTTCTTTATAGTTATGTTCAAATGA
TACTCAGTATTCATATTATCAAGGAAAAGTAAAATGTACTTGTTTTTTGTTTGGAAAATCACAC
TATATTTAACTTCACCTATAAGCTAAATTGCGAGCATAAATAACGTTATATTGACAAAACTACA
AATTAATAATTTTCATGATTTTTCATGAAAAAAGGATGATTCTATCCCAAAGAAGGAAACTTTT
AAAGACTCCCTGTAAAACTAGATATTGTTATAATTTTTGAAGTAATTATTTACACATGGAATGG
CTGACTACTGTATTTTATCATTCATGGAATATGATAGTTATCAGATTACTCAGGTGTTAGTTAA
ATAGACTATATATATTCTGTCTCAGAATAAATGTCTATAATGCTCTAATAGATTATTTTTAACA
ACAATCAAATAACTAAAATAAAAAATTGC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001233142	(Get FASTA)	NCBI Sequence Viewer
	XP_020924119	(Get FASTA)	NCBI Sequence Viewer
	XP_020924120	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AEE02034	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000023245.3
	ENSSSCP00000035245.2
	ENSSSCP00000043258
	ENSSSCP00000043258.1
	ENSSSCP00000067911.2
	ENSSSCP00000069539.1
	ENSSSCP00015021737.1
	ENSSSCP00015021989.1
	ENSSSCP00015022150.1
	ENSSSCP00015022201.1
	ENSSSCP00025005741.1
	ENSSSCP00025005812.1
	ENSSSCP00025005834.1
	ENSSSCP00025005898.1
	ENSSSCP00025005930.1
	ENSSSCP00030006435.1
	ENSSSCP00030006443.1
	ENSSSCP00030006454.1
	ENSSSCP00030006456.1
	ENSSSCP00035023091.1
	ENSSSCP00035023098.1
	ENSSSCP00035023105.1
	ENSSSCP00035023106.1
	ENSSSCP00040040888.1
	ENSSSCP00040041054.1
	ENSSSCP00040041172.1
	ENSSSCP00040041209.1
	ENSSSCP00045031001.1
	ENSSSCP00045031194.1
	ENSSSCP00045031247.1
	ENSSSCP00045031333.1
	ENSSSCP00045031423.1
	ENSSSCP00050002904.1
	ENSSSCP00050002911.1
	ENSSSCP00050002915.1
	ENSSSCP00050002918.1
	ENSSSCP00055038300.1
	ENSSSCP00055038366.1
	ENSSSCP00055038479.1
	ENSSSCP00055038592.1
	ENSSSCP00060037410.1
	ENSSSCP00060037451.1
	ENSSSCP00060037505.1
	ENSSSCP00060037542.1
	ENSSSCP00065009493.1
	ENSSSCP00070009857.1
	ENSSSCP00070009875.1
	ENSSSCP00070009899.1
	ENSSSCP00070009908.1

RefSeq Acc Id:	XP_020924119 ⟸ XM_021068460
- Peptide Label:	isoform X1
- UniProtKB:	A0A287AHC0 (UniProtKB/TrEMBL), A0A4X1T2A5 (UniProtKB/TrEMBL), A0A4X1T4A4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDNQNAQMKAPYPGTHSPAQNPPEYPSAGFSGPPGYTGHPAPQAGYPIPPAGYPAPQASYPGVG PVGFPGQHQPVSHQSGAPAGIPWMPAPPPPANCPPGLEYLTQIDQLLIHQQIELLEVLTGFETN NKYEIKNSLGQRIYFAAEDTDCCTRNCCGPSRPFTMRILDNMGREVITLERPLRCTSCCFPCCL QEIEIQAPPGIPVGYVTQTWHPCLPRFTVQNERREDVLKITGPCVVCSCCADIDFEIKSLDDKY VVGKISKQWSGLVREMFTDVDNFGIQFPLDLDVKMKAVMLGACFLIDFMFFEMTRGEQRSGVW hide sequence

RefSeq Acc Id:	XP_020924120 ⟸ XM_021068461
- Peptide Label:	isoform X1
- UniProtKB:	A0A287AHC0 (UniProtKB/TrEMBL), A0A4X1T2A5 (UniProtKB/TrEMBL), A0A4X1T4A4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDNQNAQMKAPYPGTHSPAQNPPEYPSAGFSGPPGYTGHPAPQAGYPIPPAGYPAPQASYPGVG PVGFPGQHQPVSHQSGAPAGIPWMPAPPPPANCPPGLEYLTQIDQLLIHQQIELLEVLTGFETN NKYEIKNSLGQRIYFAAEDTDCCTRNCCGPSRPFTMRILDNMGREVITLERPLRCTSCCFPCCL QEIEIQAPPGIPVGYVTQTWHPCLPRFTVQNERREDVLKITGPCVVCSCCADIDFEIKSLDDKY VVGKISKQWSGLVREMFTDVDNFGIQFPLDLDVKMKAVMLGACFLIDFMFFEMTRGEQRSGVW hide sequence

RefSeq Acc Id:

NP_001233142 ⟸ NM_001246213

- UniProtKB:

F4ZS19 (UniProtKB/TrEMBL), A0A4X1T4A4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKAPYPGTHSPAQNPPEYPSAGFSGPPGYTGHPAPQAGYPIPPAGYPAPQASYPGVGPVGFPGQ
HQPVSHQSGAPAGIPWMPAPPPPANCPPGLEYLTQIDQLLIHQQIELLEVLTGFETNNKYEIKN
SLGQRIYFAAEDTDCCTRNCCGPSRPFTMRILDNMGREVITLERPLRCTSCCFPCCLQEIEIQA
PPGIPVGYVTQTWHPCLPRFTVQNERREDVLKITGPCVVCSCCADIDFEIKSLDDKYVVGKISK
QWSGLVREMFTDVDNFGIQFPLDLDVKMKAVMLGACFLIDFMFFEMTRGEQRSGVW

hide sequence

Ensembl Acc Id:

ENSSSCP00000043258 ⟸ ENSSSCT00000049433

Ensembl Acc Id:

ENSSSCP00000069539 ⟸ ENSSSCT00000074603

Ensembl Acc Id:

ENSSSCP00000035245 ⟸ ENSSSCT00000048400

Ensembl Acc Id:

ENSSSCP00000067911 ⟸ ENSSSCT00000069560

Ensembl Acc Id:

ENSSSCP00000023245 ⟸ ENSSSCT00000031489

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000035634	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015040393	UniProtKB/TrEMBL
	ENSSSCG00025011224	UniProtKB/TrEMBL
	ENSSSCG00030010437	UniProtKB/TrEMBL
	ENSSSCG00035043239	UniProtKB/TrEMBL
	ENSSSCG00040067442	UniProtKB/TrEMBL
	ENSSSCG00045026225	UniProtKB/TrEMBL
	ENSSSCG00050004912	UniProtKB/TrEMBL
	ENSSSCG00055024151	UniProtKB/TrEMBL
	ENSSSCG00060063266	UniProtKB/TrEMBL
	ENSSSCG00065017541	UniProtKB/TrEMBL
	ENSSSCG00070006251	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000031489.4	UniProtKB/TrEMBL
	ENSSSCT00000048400.2	UniProtKB/TrEMBL
	ENSSSCT00000049433	ENTREZGENE
	ENSSSCT00000049433.2	UniProtKB/TrEMBL
	ENSSSCT00000069560.2	UniProtKB/TrEMBL
	ENSSSCT00000074603.1	UniProtKB/TrEMBL
	ENSSSCT00015054198.1	UniProtKB/TrEMBL
	ENSSSCT00015054844.1	UniProtKB/TrEMBL
	ENSSSCT00015055211.1	UniProtKB/TrEMBL
	ENSSSCT00015055299.1	UniProtKB/TrEMBL
	ENSSSCT00025014807.1	UniProtKB/TrEMBL
	ENSSSCT00025014954.1	UniProtKB/TrEMBL
	ENSSSCT00025014996.1	UniProtKB/TrEMBL
	ENSSSCT00025015099.1	UniProtKB/TrEMBL
	ENSSSCT00025015153.1	UniProtKB/TrEMBL
	ENSSSCT00030014343.1	UniProtKB/TrEMBL
	ENSSSCT00030014367.1	UniProtKB/TrEMBL
	ENSSSCT00030014392.1	UniProtKB/TrEMBL
	ENSSSCT00030014397.1	UniProtKB/TrEMBL
	ENSSSCT00035057466.1	UniProtKB/TrEMBL
	ENSSSCT00035057482.1	UniProtKB/TrEMBL
	ENSSSCT00035057496.1	UniProtKB/TrEMBL
	ENSSSCT00035057499.1	UniProtKB/TrEMBL
	ENSSSCT00040092596.1	UniProtKB/TrEMBL
	ENSSSCT00040092925.1	UniProtKB/TrEMBL
	ENSSSCT00040093180.1	UniProtKB/TrEMBL
	ENSSSCT00040093277.1	UniProtKB/TrEMBL
	ENSSSCT00045044695.1	UniProtKB/TrEMBL
	ENSSSCT00045044960.1	UniProtKB/TrEMBL
	ENSSSCT00045045055.1	UniProtKB/TrEMBL
	ENSSSCT00045045177.1	UniProtKB/TrEMBL
	ENSSSCT00045045303.1	UniProtKB/TrEMBL
	ENSSSCT00050006748.1	UniProtKB/TrEMBL
	ENSSSCT00050006756.1	UniProtKB/TrEMBL
	ENSSSCT00050006769.1	UniProtKB/TrEMBL
	ENSSSCT00050006775.1	UniProtKB/TrEMBL
	ENSSSCT00055047982.1	UniProtKB/TrEMBL
	ENSSSCT00055048066.1	UniProtKB/TrEMBL
	ENSSSCT00055048201.1	UniProtKB/TrEMBL
	ENSSSCT00055048337.1	UniProtKB/TrEMBL
	ENSSSCT00060086507.1	UniProtKB/TrEMBL
	ENSSSCT00060086595.1	UniProtKB/TrEMBL
	ENSSSCT00060086709.1	UniProtKB/TrEMBL
	ENSSSCT00060086785.1	UniProtKB/TrEMBL
	ENSSSCT00065023311.1	UniProtKB/TrEMBL
	ENSSSCT00070011960.1	UniProtKB/TrEMBL
	ENSSSCT00070011989.1	UniProtKB/TrEMBL
	ENSSSCT00070012013.1	UniProtKB/TrEMBL
	ENSSSCT00070012022.1	UniProtKB/TrEMBL
InterPro	Scramblase	UniProtKB/TrEMBL
	Tubby-like_C	UniProtKB/TrEMBL
KEGG Report	ssc:100620055	UniProtKB/TrEMBL
NCBI Gene	PLSCR1	ENTREZGENE
PANTHER	PHOSPHOLIPID SCRAMBLASE 1	UniProtKB/TrEMBL
	PTHR23248	UniProtKB/TrEMBL
Pfam	Scramblase	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54518	UniProtKB/TrEMBL
UniProt	A0A286ZUA7_PIG	UniProtKB/TrEMBL
	A0A287AHC0	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1T2A5	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1T2D7_PIG	UniProtKB/TrEMBL
	A0A4X1T4A4	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1T4V0_PIG	UniProtKB/TrEMBL
	A0A5G2QX76_PIG	UniProtKB/TrEMBL
	A0A5G2R127_PIG	UniProtKB/TrEMBL
	A0A8D0NWG1_PIG	UniProtKB/TrEMBL
	A0A8D0UHS5_PIG	UniProtKB/TrEMBL
	F4ZS19	ENTREZGENE, UniProtKB/TrEMBL
	I3LGQ1_PIG	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD