ADAM9 (ADAM metallopeptidase domain 9) - Rat Genome Database

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Pathways
Gene: ADAM9 (ADAM metallopeptidase domain 9) Sus scrofa
Analyze
Symbol: ADAM9
Name: ADAM metallopeptidase domain 9
RGD ID: 14283508
Description: ENCODES a protein that exhibits protein kinase C binding (ortholog); INVOLVED IN amyloid precursor protein catabolic process (ortholog); cell migration (ortholog); membrane protein ectodomain proteolysis (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Breast Cancer, Familial (ortholog); cervical cancer (ortholog); FOUND IN basolateral plasma membrane (ortholog); cell surface (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ADAM-9; cellular disintegrin; disintegrin and metalloproteinase domain-containing protein 9
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1547,523,771 - 47,601,710 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.11547,523,768 - 47,601,722 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21554,595,430 - 54,674,618 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:10429942   PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ADAM9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1547,523,771 - 47,601,710 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.11547,523,768 - 47,601,722 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21554,595,430 - 54,674,618 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADAM9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38838,996,973 - 39,105,261 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl838,996,754 - 39,105,447 (+)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh37838,854,492 - 38,962,780 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36838,973,662 - 39,081,937 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34838,973,661 - 39,081,934NCBI
Celera837,806,051 - 37,914,424 (+)NCBICelera
Cytogenetic Map8p11.22NCBI
HuRef837,387,348 - 37,495,887 (+)NCBIHuRef
CHM1_1839,056,582 - 39,164,835 (+)NCBICHM1_1
T2T-CHM13v2.0839,274,115 - 39,382,400 (+)NCBIT2T-CHM13v2.0
Adam9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39825,439,627 - 25,507,138 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl825,439,626 - 25,507,096 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38824,949,611 - 25,017,040 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl824,949,611 - 25,016,927 (-)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv37826,060,083 - 26,127,394 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36826,415,170 - 26,482,339 (-)NCBIMGSCv36mm8
Celera826,416,905 - 26,484,530 (-)NCBICelera
Cytogenetic Map8A2NCBI
cM Map813.7NCBI
Adam9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81673,725,186 - 73,804,284 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1673,725,114 - 73,804,646 (+)EnsemblGRCr8
mRatBN7.21667,022,538 - 67,101,647 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1667,022,655 - 67,100,917 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1672,299,877 - 72,378,087 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01675,705,845 - 75,783,765 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01670,952,385 - 71,031,826 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1673,638,943 - 73,717,156 (+)NCBI
Lyon_Normotensive1675,012,079 - 75,090,291 (+)NCBI
Lyon_Hypertensive1675,513,036 - 75,591,245 (+)NCBI
F344_StmMcwi1671,678,603 - 71,756,970 (+)NCBI
Rnor_6.01671,810,377 - 71,887,926 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1671,810,377 - 71,887,926 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.01671,459,144 - 71,536,608 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41671,446,498 - 71,526,108 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1664,927,252 - 65,004,785 (+)NCBICelera
RGSC_v3.11671,446,762 - 71,526,373 (+)NCBI
Cytogenetic Map16q12.4NCBI
Adam9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546314,545,589 - 14,645,419 (+)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_00495546314,545,425 - 14,646,498 (+)NCBIChiLan1.0ChiLan1.0
ADAM9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2757,559,148 - 57,667,461 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1833,276,626 - 33,384,700 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0838,298,194 - 38,406,706 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1835,473,280 - 35,581,192 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl835,473,278 - 35,581,192 (+)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
ADAM9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11626,413,345 - 26,551,293 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1626,414,583 - 26,551,122 (-)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1626,936,243 - 27,072,615 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01628,245,576 - 28,382,674 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1628,058,376 - 28,382,944 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11626,539,869 - 26,676,393 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01627,116,645 - 27,253,104 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01627,154,835 - 27,291,400 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Adam9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap11463,408,734 - 63,495,742 (+)NCBImIctTri1.hap1
HiC_Itri_2NW_02440494349,072,313 - 49,159,738 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367102,301,730 - 2,387,695 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367102,301,470 - 2,388,533 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAM9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap1838,743,061 - 38,856,500 (+)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_0236660524,848,368 - 4,962,432 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.1837,017,827 - 37,131,462 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl837,017,545 - 37,131,615 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Adam9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247804,482,696 - 4,612,475 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046247804,480,647 - 4,612,477 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl659,493,352 - 59,618,999 (+)Ensembl
Adam9
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11361,442,803 - 61,525,097 (+)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1

Variants

.
Variants in ADAM9
2479 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000017216   ⟹   ENSSSCP00000016755
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1547,523,771 - 47,601,587 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000037135   ⟹   ENSSSCP00000046260
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1547,525,589 - 47,601,668 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000072768   ⟹   ENSSSCP00000063603
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1547,577,723 - 47,601,710 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000079034   ⟹   ENSSSCP00000062039
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1547,540,665 - 47,601,710 (-)Ensembl
RefSeq Acc Id: XM_001925664   ⟹   XP_001925699
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11547,523,768 - 47,601,722 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021075120   ⟹   XP_020930779
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11547,523,768 - 47,601,298 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_001925699 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC23530 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000016755.2
  ENSSSCP00000046260.2
  ENSSSCP00000062039.1
  ENSSSCP00000063603.1
GenBank Protein JAG69742 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_001925699   ⟸   XM_001925664
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020930779   ⟸   XM_021075120
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSSSCP00000062039   ⟸   ENSSSCT00000079034
Ensembl Acc Id: ENSSSCP00000046260   ⟸   ENSSSCT00000037135
Ensembl Acc Id: ENSSSCP00000016755   ⟸   ENSSSCT00000017216
Ensembl Acc Id: ENSSSCP00000063603   ⟸   ENSSSCT00000072768

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015808 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017216.5 UniProtKB/TrEMBL
  ENSSSCT00000037135.2 UniProtKB/TrEMBL
  ENSSSCT00000072768.1 UniProtKB/TrEMBL
  ENSSSCT00000079034.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.390.10 UniProtKB/TrEMBL
  4.10.70.10 UniProtKB/TrEMBL
InterPro ADAM_Cys-rich UniProtKB/TrEMBL
  Disintegrin_CS UniProtKB/TrEMBL
  Disintegrin_dom UniProtKB/TrEMBL
  Disintegrin_dom_sf UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/TrEMBL
  Peptidase_M12B UniProtKB/TrEMBL
  Peptidase_M12B_N UniProtKB/TrEMBL
  Reprolysin_adamalysin UniProtKB/TrEMBL
KEGG Report ssc:397344 UniProtKB/TrEMBL
NCBI Gene ADAM9 ENTREZGENE
PANTHER ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN UniProtKB/TrEMBL
  DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 9 UniProtKB/TrEMBL
Pfam ADAM_CR UniProtKB/TrEMBL
  Disintegrin UniProtKB/TrEMBL
  Pep_M12B_propep UniProtKB/TrEMBL
  Reprolysin UniProtKB/TrEMBL
PROSITE ADAM_MEPRO UniProtKB/TrEMBL
  DISINTEGRIN_1 UniProtKB/TrEMBL
  DISINTEGRIN_2 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
SMART ACR UniProtKB/TrEMBL
  DISIN UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  SSF57552 UniProtKB/TrEMBL
UniProt A0A287AQW4_PIG UniProtKB/TrEMBL
  A0A5G2QJ41_PIG UniProtKB/TrEMBL
  A0A5G2QNE8_PIG UniProtKB/TrEMBL
  F1RZL4_PIG UniProtKB/TrEMBL
VGNC ID VGNC:95969 ENTREZGENE