ARHGAP31 (Rho GTPase activating protein 31) - Rat Genome Database

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Gene: ARHGAP31 (Rho GTPase activating protein 31) Sus scrofa
Analyze
Symbol: ARHGAP31
Name: Rho GTPase activating protein 31
RGD ID: 13870012
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); SH3 domain binding (inferred); INVOLVED IN small GTPase-mediated signal transduction (ortholog); ASSOCIATED WITH Adams-Oliver syndrome (ortholog); Adams-Oliver Syndrome 1 (ortholog); cerebral palsy (ortholog); FOUND IN lamellipodium (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rho GTPase-activating protein 31
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13140,839,268 - 140,948,303 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113140,837,078 - 140,948,504 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213150,136,809 - 150,239,772 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
lamellipodium  (IBA,IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ARHGAP31
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13140,839,268 - 140,948,303 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113140,837,078 - 140,948,504 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213150,136,809 - 150,239,772 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGAP31
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383119,294,383 - 119,420,714 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3119,294,383 - 119,420,714 (+)EnsemblGRCh38hg38GRCh38
GRCh373119,013,230 - 119,139,561 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363120,495,910 - 120,619,254 (+)NCBINCBI36Build 36hg18NCBI36
Celera3117,421,692 - 117,546,790 (+)NCBICelera
Cytogenetic Map3q13.32-q13.33NCBI
HuRef3116,388,684 - 116,513,719 (+)NCBIHuRef
CHM1_13118,976,689 - 119,101,812 (+)NCBICHM1_1
T2T-CHM13v2.03122,014,089 - 122,140,425 (+)NCBIT2T-CHM13v2.0
Arhgap31
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391638,418,705 - 38,533,397 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1638,418,702 - 38,533,636 (-)EnsemblGRCm39 Ensembl
GRCm381638,598,343 - 38,713,035 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1638,598,340 - 38,713,274 (-)EnsemblGRCm38mm10GRCm38
MGSCv371638,598,456 - 38,713,148 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361638,517,675 - 38,632,367 (-)NCBIMGSCv36mm8
Celera1639,010,417 - 39,125,124 (-)NCBICelera
Cytogenetic Map16B4NCBI
cM Map1626.87NCBI
Arhgap31
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81175,544,176 - 75,657,087 (+)NCBIGRCr8
mRatBN7.21162,038,635 - 62,151,564 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1162,038,635 - 62,151,564 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1170,851,189 - 70,964,088 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01163,513,440 - 63,626,349 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01162,564,734 - 62,677,535 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01164,600,968 - 64,714,114 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1164,601,029 - 64,714,252 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01167,395,537 - 67,508,274 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41163,814,916 - 63,929,011 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11163,872,720 - 63,986,540 (+)NCBI
Celera1161,541,526 - 61,654,475 (+)NCBICelera
Cytogenetic Map11q21NCBI
Arhgap31
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542719,019,511 - 19,131,755 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542719,019,008 - 19,136,298 (+)NCBIChiLan1.0ChiLan1.0
ARHGAP31
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22117,265,933 - 117,393,855 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13117,270,771 - 117,395,513 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03116,412,238 - 116,536,900 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13123,324,166 - 123,450,236 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3123,324,166 - 123,450,236 (+)Ensemblpanpan1.1panPan2
ARHGAP31
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13322,965,941 - 23,079,590 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3322,965,599 - 23,074,943 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3322,997,524 - 23,117,417 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03323,203,701 - 23,317,657 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3323,203,119 - 23,312,748 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13323,006,505 - 23,122,494 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03323,044,238 - 23,157,273 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03323,612,197 - 23,731,463 (+)NCBIUU_Cfam_GSD_1.0
Arhgap31
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602131,151,620 - 131,260,229 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365366,261,910 - 6,365,782 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365366,261,837 - 6,369,318 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP31
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12261,415,805 - 61,543,679 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2261,415,804 - 61,543,834 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041104,786,579 - 104,909,803 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgap31
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473128,785,015 - 28,894,645 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473128,780,180 - 28,894,018 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ARHGAP31
2263 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000031238   ⟹   ENSSSCP00000023886
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13140,837,081 - 140,947,991 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000064569   ⟹   ENSSSCP00000046617
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13140,839,268 - 140,948,303 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000068508   ⟹   ENSSSCP00000070733
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13140,837,081 - 140,947,991 (-)Ensembl
RefSeq Acc Id: XM_021070329   ⟹   XP_020925988
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113140,837,078 - 140,948,503 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021070330   ⟹   XP_020925989
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113140,837,078 - 140,948,504 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020925989   ⟸   XM_021070330
- Peptide Label: isoform X2
- UniProtKB: A0A4X1T2Y1 (UniProtKB/TrEMBL),   K9IWF6 (UniProtKB/TrEMBL),   I3LII1 (UniProtKB/TrEMBL),   A0A8D1KKI6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020925988   ⟸   XM_021070329
- Peptide Label: isoform X1
- UniProtKB: A0A8D1KKI6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000046617   ⟸   ENSSSCT00000064569
Ensembl Acc Id: ENSSSCP00000070733   ⟸   ENSSSCT00000068508
Ensembl Acc Id: ENSSSCP00000023886   ⟸   ENSSSCT00000031238
Protein Domains
Rho-GAP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000026224 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015011028 UniProtKB/TrEMBL
  ENSSSCG00025072844 UniProtKB/TrEMBL
  ENSSSCG00030045649 UniProtKB/TrEMBL
  ENSSSCG00035007213 UniProtKB/TrEMBL
  ENSSSCG00040069430 UniProtKB/TrEMBL
  ENSSSCG00050072845 UniProtKB/TrEMBL
  ENSSSCG00055001915 UniProtKB/TrEMBL
  ENSSSCG00060075763 UniProtKB/TrEMBL
  ENSSSCG00065032010 UniProtKB/TrEMBL
  ENSSSCG00070005784 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000064569 ENTREZGENE
  ENSSSCT00000064569.3 UniProtKB/TrEMBL
  ENSSSCT00015014522.1 UniProtKB/TrEMBL
  ENSSSCT00015014634.1 UniProtKB/TrEMBL
  ENSSSCT00025100221.1 UniProtKB/TrEMBL
  ENSSSCT00025100374.1 UniProtKB/TrEMBL
  ENSSSCT00030063702.1 UniProtKB/TrEMBL
  ENSSSCT00030063727.1 UniProtKB/TrEMBL
  ENSSSCT00035008960.1 UniProtKB/TrEMBL
  ENSSSCT00035008964.1 UniProtKB/TrEMBL
  ENSSSCT00040095434.1 UniProtKB/TrEMBL
  ENSSSCT00050099480.1 UniProtKB/TrEMBL
  ENSSSCT00050099492.1 UniProtKB/TrEMBL
  ENSSSCT00055003563.1 UniProtKB/TrEMBL
  ENSSSCT00055003569.1 UniProtKB/TrEMBL
  ENSSSCT00060103816.1 UniProtKB/TrEMBL
  ENSSSCT00060103839.1 UniProtKB/TrEMBL
  ENSSSCT00065043357.1 UniProtKB/TrEMBL
  ENSSSCT00065043361.1 UniProtKB/TrEMBL
  ENSSSCT00070011026.1 UniProtKB/TrEMBL
  ENSSSCT00070011033.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
InterPro PX-Rho_GAP UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
NCBI Gene ARHGAP31 ENTREZGENE
PANTHER CDC42 GTPASE-ACTIVATING PROTEIN UniProtKB/TrEMBL
  RHO GTPASE-ACTIVATING PROTEIN 31 UniProtKB/TrEMBL
Pfam RhoGAP UniProtKB/TrEMBL
PROSITE RHOGAP UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/TrEMBL
UniProt A0A287ART1_PIG UniProtKB/TrEMBL
  A0A4X1T1E1_PIG UniProtKB/TrEMBL
  A0A4X1T2Y1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1KKI6 ENTREZGENE, UniProtKB/TrEMBL
  I3LII1 ENTREZGENE, UniProtKB/TrEMBL
  K9IWF6 ENTREZGENE
UniProt Secondary A0A5G2R0U1 UniProtKB/TrEMBL
  K9IWF6 UniProtKB/TrEMBL
VGNC ID VGNC:85470 ENTREZGENE