Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:neural tube closure
go back to main search page
Accession:GO:0001843 term browser browse the term
Definition:The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.


show annotations for term's descendants           Sort by:
neural tube closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9883720) Ensembl
MGI		 PMID:9883720 GO_REF:0000107 NCBI chr 1:270,761,641...270,906,708
Ensembl chr 1:270,761,668...270,906,708 		JBrowse link
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:9883720) MGI PMID:9883720 NCBI chr 9:120,888,891...120,984,724
Ensembl chr 9:120,892,952...120,984,695 		JBrowse link
G ADM adrenomedullin acts_upstream_of_or_within ISO (PMID:16981008) MGI PMID:16981008 NCBI chr 2:49,229,223...49,231,521
Ensembl chr 2:49,229,223...49,231,866 		JBrowse link
G ALX1 ALX homeobox 1 acts_upstream_of_or_within ISO (PMID:8673125) MGI PMID:8673125 NCBI chr 5:96,761,683...96,785,125
Ensembl chr 5:96,763,685...96,785,165 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11504943), (PMID:9216040) Ensembl
MGI		 PMID:9216040 PMID:11504943 GO_REF:0000107 NCBI chr 5:85,166,616...85,258,751
Ensembl chr 5:85,166,628...85,258,364 		JBrowse link
G ARHGAP35 Rho GTPase activating protein 35 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11044403) Ensembl
MGI		 PMID:11044403 GO_REF:0000107 NCBI chr 6:52,711,463...52,841,295
Ensembl chr 6:52,711,901...52,841,288 		JBrowse link
G ARID1A AT-rich interaction domain 1A acts_upstream_of_or_within ISO (PMID:23129809) MGI PMID:23129809 NCBI chr 6:84,049,729...84,124,302
Ensembl chr 6:84,049,087...84,123,349 		JBrowse link
G BBS4 Bardet-Biedl syndrome 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16170314) Ensembl
MGI		 PMID:16170314 GO_REF:0000107 NCBI chr 7:60,631,913...60,693,359
Ensembl chr 7:60,631,914...60,693,334 		JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:130,645,427...130,653,317
Ensembl chr 4:130,645,216...130,657,995 		JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19850029) Ensembl
MGI		 PMID:19850029 GO_REF:0000107 NCBI chr 1:183,415,989...183,422,888
Ensembl chr 1:183,416,146...183,422,637 		JBrowse link
G BRD2 bromodomain containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19362612) Ensembl
MGI		 PMID:19362612 GO_REF:0000107 NCBI chr 7:25,096,579...25,162,591
Ensembl chr 7:25,152,043...25,162,578 		JBrowse link
G CC2D2A coiled-coil and C2 domain containing 2A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24947469) Ensembl
MGI		 PMID:24947469 GO_REF:0000107 NCBI chr 8:10,779,206...10,898,189
Ensembl chr 8:10,779,334...10,898,190 		JBrowse link
G CDK20 cyclin dependent kinase 20 acts_upstream_of_or_within ISO (PMID:28817564) MGI PMID:28817564 NCBI chr14:15,582...24,102 JBrowse link
G CECR2 CECR2 histone acetyl-lysine reader involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20589882)
(PMID:15640247)
(PMID:21246654)		 Ensembl
MGI		 PMID:15640247 PMID:20589882 PMID:21246654 GO_REF:0000107 NCBI chr 5:69,621,871...69,747,730
Ensembl chr 5:69,621,959...69,740,958 		JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12149478) Ensembl
MGI		 PMID:12149478 GO_REF:0000107 NCBI chr 1:25,155,652...25,158,517
Ensembl chr 1:25,155,664...25,160,279 		JBrowse link
G CLUAP1 clusterin associated protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23742838) Ensembl
MGI		 PMID:23742838 GO_REF:0000107 NCBI chr 3:38,716,562...38,753,743
Ensembl chr 3:38,716,431...38,753,748 		JBrowse link
G COBL cordon-bleu WH2 repeat protein acts_upstream_of_or_within ISO (PMID:14512015) MGI PMID:14512015 NCBI chr 9:136,850,521...137,055,249 JBrowse link
G DEAF1 DEAF1 transcription factor involved_in ISO (MGI:3029622|PMID:14966286) UniProt PMID:14966286 MGI:3029622 NCBI chr 2:404,514...427,584
Ensembl chr 2:404,533...427,542 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein acts_upstream_of_or_within ISO (PMID:15710412) MGI PMID:15710412 NCBI chr17:1,169,709...1,637,171
Ensembl chr17:1,170,208...1,637,114 		JBrowse link
G DVL2 dishevelled segment polarity protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12421720) Ensembl
MGI		 PMID:12421720 GO_REF:0000107 NCBI chr12:52,581,687...52,590,266
Ensembl chr12:52,581,688...52,590,285 		JBrowse link
G ENAH ENAH actin regulator acts_upstream_of_or_within ISO (PMID:15371503)
(PMID:10069337)		 MGI PMID:10069337 PMID:15371503 NCBI chr10:13,439,772...13,609,347
Ensembl chr10:13,446,426...13,609,303 		JBrowse link
G FUZ fuzzy planar cell polarity protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19877275) Ensembl
MGI		 PMID:19877275 GO_REF:0000107 NCBI chr 6:54,823,680...54,830,425
Ensembl chr 6:54,823,668...54,829,506 		JBrowse link
G FZD3 frizzled class receptor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16495441) Ensembl
MGI		 PMID:16495441 GO_REF:0000107 NCBI chr14:12,281,127...12,394,768
Ensembl chr14:12,281,155...12,390,530 		JBrowse link
G FZD6 frizzled class receptor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16495441) Ensembl
MGI		 PMID:16495441 GO_REF:0000107 NCBI chr 4:33,811,159...33,844,556
Ensembl chr 4:33,809,809...33,844,656 		JBrowse link
G GLMN glomulin, FKBP associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22405651) Ensembl
MGI		 PMID:22405651 GO_REF:0000107 NCBI chr 4:124,773,957...124,813,336
Ensembl chr 4:124,773,980...124,813,335 		JBrowse link
G GRHL2 grainyhead like transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21262862) Ensembl
MGI		 PMID:21262862 GO_REF:0000107 NCBI chr 4:35,368,788...35,565,394
Ensembl chr 4:35,371,136...35,564,919 		JBrowse link
G GRHL3 grainyhead like transcription factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:82,014,022...82,050,240
Ensembl chr 6:82,013,969...82,050,236 		JBrowse link
G HECTD1 HECT domain E3 ubiquitin protein ligase 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:3714713|PMID:17442300)
(PMID:15755804), (PMID:9636176)		 UniProt
MGI		 PMID:9636176 PMID:15755804 PMID:17442300 MGI:3714713 NCBI chr 7:68,318,167...68,422,403
Ensembl chr 7:68,318,417...68,422,394 		JBrowse link
G IFT122 intraflagellar transport 122 involved_in ISO (MGI:3827087|PMID:19000668) UniProt PMID:19000668 MGI:3827087 NCBI chr13:68,828,710...68,902,062
Ensembl chr13:68,828,719...68,902,060 		JBrowse link
G IFT172 intraflagellar transport 172 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18930042) Ensembl
MGI		 PMID:18930042 GO_REF:0000107 NCBI chr 3:111,683,674...111,718,504
Ensembl chr 3:111,683,669...111,718,970 		JBrowse link
G IFT57 intraflagellar transport 57 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17027958) Ensembl
MGI		 PMID:17027958 GO_REF:0000107 NCBI chr13:151,298,552...151,356,715
Ensembl chr13:151,298,554...151,357,155 		JBrowse link
G KAT2A lysine acetyltransferase 2A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17325035) Ensembl
MGI		 PMID:17325035 GO_REF:0000107 NCBI chr12:20,638,493...20,647,464
Ensembl chr12:20,638,497...20,647,461 		JBrowse link
G KDM2A lysine demethylase 2A acts_upstream_of_or_within ISO (PMID:25463925) MGI PMID:25463925 NCBI chr 2:5,238,690...5,357,799
Ensembl chr 2:5,240,312...5,357,829 		JBrowse link
G KDM6A lysine demethylase 6A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22949634) Ensembl
MGI		 PMID:22949634 GO_REF:0000107 NCBI chr  X:39,953,764...40,154,197
Ensembl chr  X:39,953,814...40,154,029 		JBrowse link
G KIF20B kinesin family member 20B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15755804) Ensembl
MGI		 PMID:15755804 GO_REF:0000107 NCBI chr14:101,512,685...101,594,703
Ensembl chr14:101,512,814...101,594,696 		JBrowse link
G LHX2 LIM homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11719201) Ensembl
MGI		 PMID:11719201 GO_REF:0000107 NCBI chr 1:264,900,931...264,920,888
Ensembl chr 1:264,900,591...264,920,890 		JBrowse link
G LIAS lipoic acid synthetase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15755804) Ensembl
MGI		 PMID:15755804 GO_REF:0000107 NCBI chr 8:30,699,278...30,717,009
Ensembl chr 8:30,699,330...30,720,335 		JBrowse link
G LMO4 LIM domain only 4 involved_in
acts_upstream_of_or_within		 ISO (MGI:3689640|PMID:16949565)
(PMID:14966285)
(PMID:15691703)		 UniProt
MGI		 PMID:14966285 PMID:15691703 PMID:16949565 MGI:3689640 NCBI chr 4:128,894,113...128,910,648 JBrowse link
G LOC102159820 cadherin EGF LAG seven-pass G-type receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17229766) Ensembl
MGI		 PMID:17229766 GO_REF:0000107 NCBI chr 5:3,114,410...3,203,378
Ensembl chr 5:2,980,351...3,203,381 		JBrowse link
G LRP2 LDL receptor related protein 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:75,565,299...75,754,604
Ensembl chr15:75,565,303...75,716,694 		JBrowse link
G LRP6 LDL receptor related protein 6 acts_upstream_of_or_within ISO (PMID:15469977)
(PMID:19653321)
(PMID:19056682)
(PMID:10545599)
(PMID:19795512)		 MGI PMID:10545599 PMID:15469977 PMID:19056682 PMID:19653321 PMID:19795512 MGI:61254 NCBI chr 5:60,149,041...60,318,719
Ensembl chr 5:60,149,028...60,314,662 		JBrowse link
G MED12 mediator complex subunit 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20630950) Ensembl
MGI		 PMID:20630950 GO_REF:0000107 NCBI chr  X:57,150,884...57,174,367
Ensembl chr  X:57,150,919...57,175,333 		JBrowse link
G MED18 mediator complex subunit 18 involved_in IEA UniProt GO_REF:0000104 NCBI chr 6:85,384,085...85,392,296
Ensembl chr 6:85,384,080...85,392,291 		JBrowse link
G MKS1 MKS transition zone complex subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19776033)
(PMID:23454480)		 Ensembl
MGI		 PMID:19776033 PMID:23454480 GO_REF:0000107 NCBI chr12:34,499,139...34,512,191
Ensembl chr12:34,499,142...34,512,187 		JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (MGI:5503248|PMID:23704330) BHF-UCL PMID:23704330 MGI:5503248 NCBI chr 7:88,471,317...88,533,690
Ensembl chr 7:88,471,414...88,537,387 		JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:15,140,929...15,330,265
Ensembl chr 1:15,140,899...15,329,986 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase acts_upstream_of
involved_in		 ISO
IEA		 (PMID:25855017), (PMID:29222906) BHF-UCL
Ensembl		 PMID:25855017 PMID:29222906 GO_REF:0000107 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820 		JBrowse link
G NCKAP1 NCK associated protein 1 acts_upstream_of_or_within ISO (PMID:16831833) MGI PMID:16831833 NCBI chr15:88,425,861...88,528,417
Ensembl chr15:88,425,142...88,528,326 		JBrowse link
G NOG noggin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16712836) Ensembl
MGI		 PMID:16712836 GO_REF:0000107 NCBI chr12:32,891,321...32,892,206
Ensembl chr12:32,891,321...32,892,206 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15755804) Ensembl
MGI		 PMID:15755804 GO_REF:0000107 NCBI chr13:130,624,771...130,718,345
Ensembl chr13:130,624,796...130,719,083 		JBrowse link
G PAX2 paired box 2 involved_in ISO (MGI:84247|PMID:8951055) DFLAT PMID:8951055 MGI:84247 NCBI chr14:111,822,334...111,914,950
Ensembl chr14:111,823,308...111,913,969 		JBrowse link
G PAX3 paired box 3 acts_upstream_of_or_within ISO (PMID:15384171) MGI PMID:15384171 NCBI chr15:124,093,803...124,193,041
Ensembl chr15:124,094,295...124,193,011 		JBrowse link
G PFN1 profilin 1 acts_upstream_of_or_within ISO (PMID:10069337) MGI PMID:10069337 NCBI chr12:51,962,642...51,965,570
Ensembl chr12:51,961,952...51,965,464 		JBrowse link
G PHACTR4 phosphatase and actin regulator 4 involved_in IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr 6:85,411,993...85,529,441
Ensembl chr 6:85,412,134...85,528,715 		JBrowse link
G PLXNB2 plexin B2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:390,347...416,805
Ensembl chr 5:403,765...416,798 		JBrowse link
G PRICKLE1 prickle planar cell polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:73,707,026...73,826,529
Ensembl chr 5:73,707,050...73,826,430 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22007132) Ensembl
MGI		 PMID:22007132 GO_REF:0000107 NCBI chr 2:65,074,876...65,095,564
Ensembl chr 2:65,074,870...65,095,551 		JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22007132) Ensembl
MGI		 PMID:22007132 GO_REF:0000107 NCBI chr 6:129,520,397...129,636,207
Ensembl chr 6:129,520,376...129,635,733 		JBrowse link
G PTCH1 patched 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9262482) Ensembl
MGI		 PMID:9262482 GO_REF:0000107 NCBI chr10:26,627,165...26,703,225
Ensembl chr10:26,627,425...26,703,223 		JBrowse link
G PTK7 protein tyrosine kinase 7 (inactive) involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15229603)
(PMID:20704721)		 Ensembl
MGI		 PMID:15229603 PMID:20704721 GO_REF:0000107 NCBI chr 7:38,135,675...38,205,662
Ensembl chr 7:38,135,655...38,205,655 		JBrowse link
G RAB23 RAB23, member RAS oncogene family involved_in
acts_upstream_of_or_within		 ISO (MGI:69552|PMID:7720556)
(PMID:9636176)		 UniProt
MGI		 PMID:7720556 PMID:9636176 MGI:69552 NCBI chr 7:28,632,065...28,658,958
Ensembl chr 7:28,632,082...28,658,952 		JBrowse link
G RALA RAS like proto-oncogene A involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:54,548,523...54,630,746
Ensembl chr18:54,550,238...54,588,980 		JBrowse link
G RARA retinoic acid receptor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7607067) Ensembl
MGI		 PMID:7607067 GO_REF:0000107 NCBI chr12:22,047,449...22,085,759
Ensembl chr12:22,047,443...22,085,673 		JBrowse link
G RARG retinoic acid receptor gamma involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7607067) Ensembl
MGI		 PMID:7607067 GO_REF:0000107 NCBI chr 5:18,436,267...18,458,625
Ensembl chr 5:18,436,270...18,458,624 		JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14749425) Ensembl
MGI		 PMID:14749425 GO_REF:0000107 NCBI chr 7:85,921,524...85,968,887
Ensembl chr 7:85,921,594...85,968,888 		JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 acts_upstream_of_or_within ISO (PMID:17229766) MGI PMID:17229766 NCBI chr 3:125,353,063...125,493,368
Ensembl chr 3:125,352,920...125,493,362 		JBrowse link
G RPS7 ribosomal protein S7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15384171) Ensembl
MGI		 PMID:15384171 GO_REF:0000107 NCBI chr 3:131,258,709...131,263,285
Ensembl chr 3:131,258,722...131,263,256 		JBrowse link
G SALL1 spalt like transcription factor 1 acts_upstream_of_or_within ISO (PMID:16790473) MGI PMID:16790473 NCBI chr 6:33,731,666...33,748,698
Ensembl chr 6:33,732,025...33,748,704 		JBrowse link
G SALL4 spalt like transcription factor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16790473) Ensembl
MGI		 PMID:16790473 GO_REF:0000107 NCBI chr17:53,082,610...53,103,023
Ensembl chr17:53,084,310...53,103,190 		JBrowse link
G SCRIB scribble planar cell polarity protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21515572)
(PMID:20643356)		 Ensembl
MGI		 PMID:20643356 PMID:21515572 GO_REF:0000107 NCBI chr 4:824,925...852,360
Ensembl chr 4:825,062...852,664 		JBrowse link
G SDC4 syndecan 4 acts_upstream_of_or_within ISO (PMID:23760952) MGI PMID:23760952 NCBI chr17:47,650,387...47,670,499 JBrowse link
G SEC24B SEC24 homolog B, COPII coat complex component involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19966784)
(PMID:20215345)		 Ensembl
MGI		 PMID:19966784 PMID:20215345 GO_REF:0000107 NCBI chr 8:112,670,529...112,762,870
Ensembl chr 8:112,670,533...112,762,858 		JBrowse link
G SEMA4C semaphorin 4C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:56,750,745...56,760,835
Ensembl chr 3:56,750,760...56,760,828 		JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20133625) Ensembl
MGI		 PMID:20133625 GO_REF:0000107 NCBI chr13:29,884,708...29,996,285
Ensembl chr13:29,884,719...29,996,359 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19850029) Ensembl
MGI		 PMID:19850029 GO_REF:0000107 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748 		JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19850029) Ensembl
MGI		 PMID:19850029 GO_REF:0000107 NCBI chr 8:75,337,311...75,345,926
Ensembl chr 8:75,337,144...75,345,921 		JBrowse link
G SHROOM3 shroom family member 3 acts_upstream_of_or_within ISO (PMID:16249236) MGI PMID:16249236 NCBI chr 8:72,097,561...72,443,869 JBrowse link
G SKI SKI proto-oncogene acts_upstream_of_or_within ISO (PMID:9284043) MGI PMID:9284043 NCBI chr 6:64,188,265...64,242,596
Ensembl chr 6:64,188,236...64,242,560 		JBrowse link
G SPINT1 serine peptidase inhibitor, Kunitz type 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19592578) Ensembl
MGI		 PMID:19592578 GO_REF:0000107 NCBI chr 1:130,458,909...130,473,791
Ensembl chr 1:130,458,909...130,473,783 		JBrowse link
G SPINT2 serine peptidase inhibitor, Kunitz type 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19592578) Ensembl
MGI		 PMID:19592578 GO_REF:0000107 NCBI chr 6:47,181,772...47,210,564
Ensembl chr 6:47,181,768...47,210,559 		JBrowse link
G ST14 ST14 transmembrane serine protease matriptase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19592578) Ensembl
MGI		 PMID:19592578 GO_REF:0000107 NCBI chr 9:56,888,246...56,929,771
Ensembl chr 9:56,888,246...56,929,767 		JBrowse link
G STIL STIL centriolar assembly protein acts_upstream_of_or_within ISO (PMID:10385121) MGI PMID:10385121 NCBI chr 6:164,197,511...164,266,615
Ensembl chr 6:164,197,600...164,265,818 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16155214) Ensembl
MGI		 PMID:16155214 GO_REF:0000107 NCBI chr14:113,500,001...113,628,064
Ensembl chr14:113,500,842...113,626,003 		JBrowse link
G TBXT T-box transcription factor T involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16835439) Ensembl
MGI		 PMID:16835439 GO_REF:0000107 NCBI chr 1:2,717,165...2,725,561
Ensembl chr 1:2,717,165...2,725,601 		JBrowse link
G TEAD2 TEA domain transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17868131) Ensembl
MGI		 PMID:17868131 GO_REF:0000107 NCBI chr 6:54,448,183...54,462,325
Ensembl chr 6:54,448,191...54,462,210 		JBrowse link
G TFAP2A transcription factor AP-2 alpha acts_upstream_of_or_within ISO (PMID:8622766), (PMID:9811866) MGI PMID:8622766 PMID:9811866 NCBI chr 7:7,221,654...7,244,626
Ensembl chr 7:7,221,656...7,244,612 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in ISO (MGI:74339|PMID:7600998) BHF-UCL PMID:7600998 MGI:74339 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISO (MGI:894212|PMID:9217007) BHF-UCL PMID:9217007 MGI:894212 NCBI chr10:8,306,136...8,435,307
Ensembl chr10:8,305,539...8,390,341 		JBrowse link
G TGIF1 TGFB induced factor homeobox 1 acts_upstream_of_or_within ISO (PMID:17082251) MGI PMID:17082251 NCBI chr 6:103,226,395...103,234,591
Ensembl chr 6:103,226,402...103,234,610 		JBrowse link
G TMED2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within ISO (PMID:20178780) MGI PMID:20178780 NCBI chr14:29,390,903...29,400,454
Ensembl chr14:29,390,335...29,400,440 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in ISO (MGI:2181331|PMID:11007897) UniProt PMID:11007897 MGI:2181331 NCBI chr 2:24,602,749...24,628,263
Ensembl chr 2:24,602,804...24,626,072 		JBrowse link
G TRIM71 tripartite motif containing 71 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19098426) Ensembl
MGI		 PMID:19098426 GO_REF:0000107 NCBI chr13:18,762,043...18,835,788
Ensembl chr13:18,761,950...18,831,564 		JBrowse link
G TSC1 TSC complex subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11438694) Ensembl
MGI		 PMID:11438694 GO_REF:0000107 NCBI chr 1:272,636,530...272,685,948
Ensembl chr 1:272,636,532...272,685,951 		JBrowse link
G TSC2 TSC complex subunit 2 acts_upstream_of_or_within ISO (PMID:10096549) MGI PMID:10096549 NCBI chr 3:39,898,924...39,935,579
Ensembl chr 3:39,898,925...39,937,371 		JBrowse link
G TULP3 TUB like protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19223390) Ensembl
MGI		 PMID:19223390 GO_REF:0000107 NCBI chr 5:67,201,680...67,238,348
Ensembl chr 5:67,199,448...67,238,322 		JBrowse link
G TWIST1 twist family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7729687) Ensembl
MGI		 PMID:7729687 GO_REF:0000107 NCBI chr 9:88,286,911...88,290,131
Ensembl chr 9:88,289,407...88,290,015 		JBrowse link
G VANGL2 VANGL planar cell polarity protein 2 acts_upstream_of_or_within ISO (PMID:19966784)
(PMID:17229766)
(PMID:21246654)
(PMID:17433286)
(PMID:23760952)
(PMID:15229603)
(PMID:11709546), (PMID:12499390)
(PMID:14512015)		 MGI PMID:11709546 PMID:12499390 PMID:14512015 PMID:15229603 PMID:17229766 More... NCBI chr 4:90,051,994...90,080,701
Ensembl chr 4:90,051,277...90,080,635 		JBrowse link
G VASP vasodilator stimulated phosphoprotein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15371503) Ensembl
MGI
TreeGrafter		 PMID:15371503 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:51,872,810...51,886,729
Ensembl chr 6:51,872,812...51,886,724 		JBrowse link
G WDR83 WD repeat domain 83 acts_upstream_of_or_within ISO (PMID:37509073) MGI PMID:37509073 NCBI chr 2:66,307,652...66,312,839
Ensembl chr 2:66,307,653...66,312,844 		JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17433286)
(PMID:19795512)		 Ensembl
MGI		 PMID:17433286 PMID:19795512 GO_REF:0000107 NCBI chr13:37,344,684...37,367,215
Ensembl chr13:37,344,699...37,367,207 		JBrowse link
G ZEB2 zinc finger E-box binding homeobox 2 acts_upstream_of_or_within ISO (PMID:16598713) MGI PMID:16598713 NCBI chr15:7,498,879...7,631,347
Ensembl chr15:7,499,026...7,632,655 		JBrowse link
G ZIC2 Zic family member 2 acts_upstream_of_or_within ISO (PMID:15384171) MGI PMID:15384171 NCBI chr11:68,840,802...68,845,441
Ensembl chr11:68,840,631...68,845,378 		JBrowse link
G ZIC5 Zic family member 5 acts_upstream_of_or_within ISO (PMID:15136147) MGI PMID:15136147 NCBI chr11:68,821,733...68,830,472
Ensembl chr11:68,821,735...68,830,540 		JBrowse link
anterior neural tube closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21515572) Ensembl
MGI		 PMID:21515572 GO_REF:0000107 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G FOLR1 folate receptor alpha involved_in ISO (MGI:3721767|PMID:17286298) BHF-UCL PMID:17286298 MGI:3721767 NCBI chr 9:6,753,513...6,760,433
Ensembl chr 9:6,757,040...6,760,402 		JBrowse link
G GRHL2 grainyhead like transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21515572) Ensembl
MGI		 PMID:21515572 GO_REF:0000107 NCBI chr 4:35,368,788...35,565,394
Ensembl chr 4:35,371,136...35,564,919 		JBrowse link
G SPECC1L sperm antigen with calponin homology and coiled-coil domains 1 like acts_upstream_of_or_within ISO (PMID:26787558) MGI PMID:26787558 NCBI chr14:49,332,937...49,463,965
Ensembl chr14:49,333,009...49,463,963 		JBrowse link
anterior neuropore closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATAD2A GATA zinc finger domain containing 2A acts_upstream_of_or_within ISO (PMID:17565372) MGI PMID:17565372 NCBI chr 2:58,415,749...58,517,308
Ensembl chr 2:58,415,750...58,517,162 		JBrowse link
G TFAP2A transcription factor AP-2 alpha acts_upstream_of_or_within ISO (PMID:8622765) MGI PMID:8622765 NCBI chr 7:7,221,654...7,244,626
Ensembl chr 7:7,221,656...7,244,612 		JBrowse link
establishment of planar polarity involved in neural tube closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTHRC1 collagen triple helix repeat containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18606138) Ensembl
MGI		 PMID:18606138 GO_REF:0000107 NCBI chr 4:33,759,541...33,771,625
Ensembl chr 4:33,759,542...33,771,582 		JBrowse link
G VANGL2 VANGL planar cell polarity protein 2 acts_upstream_of_or_within ISO (PMID:18606138) MGI PMID:18606138 NCBI chr 4:90,051,994...90,080,701
Ensembl chr 4:90,051,277...90,080,635 		JBrowse link
initiation of neural tube closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDM2B lysine demethylase 2B involved_in ISO (MGI:4949568|PMID:21220025) BHF-UCL PMID:21220025 MGI:4949568 NCBI chr14:31,057,121...31,203,093
Ensembl chr14:31,165,950...31,203,091 		JBrowse link
negative regulation of planar cell polarity pathway involved in neural tube closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRP6 LDL receptor related protein 6 acts_upstream_of_or_within ISO (PMID:19056682) MGI PMID:19056682 NCBI chr 5:60,149,041...60,318,719
Ensembl chr 5:60,149,028...60,314,662 		JBrowse link
planar cell polarity pathway involved in neural tube closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DVL1 dishevelled segment polarity protein 1 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:16571627) Ensembl
GO_Central
TreeGrafter
MGI		 PMID:16571627 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:63,617,787...63,628,965
Ensembl chr 6:63,617,789...63,628,913 		JBrowse link
G DVL2 dishevelled segment polarity protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:16571627) Ensembl
MGI
TreeGrafter
GO_Central		 PMID:16571627 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:52,581,687...52,590,266
Ensembl chr12:52,581,688...52,590,285 		JBrowse link
G DVL3 dishevelled segment polarity protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:19008950) TreeGrafter
MGI
GO_Central		 PMID:19008950 GO_REF:0000033 GO_REF:0000118 NCBI chr13:122,075,851...122,092,975
Ensembl chr13:122,076,003...122,092,971 		JBrowse link
G FZD1 frizzled class receptor 1 acts_upstream_of_or_within ISO (PMID:20940229) MGI PMID:20940229 NCBI chr 9:71,346,994...71,356,488
Ensembl chr 9:71,349,988...71,352,104 		JBrowse link
G FZD2 frizzled class receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20940229) Ensembl
MGI		 PMID:20940229 GO_REF:0000107 NCBI chr12:18,740,417...18,742,301
Ensembl chr12:18,740,653...18,742,420 		JBrowse link
G GRHL3 grainyhead like transcription factor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20643356) Ensembl
MGI		 PMID:20643356 GO_REF:0000107 NCBI chr 6:82,014,022...82,050,240
Ensembl chr 6:82,013,969...82,050,236 		JBrowse link
G LOC102159820 cadherin EGF LAG seven-pass G-type receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20704721) Ensembl
MGI		 PMID:20704721 GO_REF:0000107 NCBI chr 5:3,114,410...3,203,378
Ensembl chr 5:2,980,351...3,203,381 		JBrowse link
G PTK7 protein tyrosine kinase 7 (inactive) involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20704721) Ensembl
MGI		 PMID:20704721 GO_REF:0000107 NCBI chr 7:38,135,675...38,205,662
Ensembl chr 7:38,135,655...38,205,655 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18257070) Ensembl
MGI		 PMID:18257070 GO_REF:0000107 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748 		JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18257070) Ensembl
MGI		 PMID:18257070 GO_REF:0000107 NCBI chr 8:75,337,311...75,345,926
Ensembl chr 8:75,337,144...75,345,921 		JBrowse link
G SFRP5 secreted frizzled related protein 5 acts_upstream_of_or_within ISO (PMID:18257070) MGI PMID:18257070 NCBI chr14:109,120,382...109,125,655
Ensembl chr14:109,119,822...109,125,686 		JBrowse link
G VANGL2 VANGL planar cell polarity protein 2 acts_upstream_of_or_within ISO (PMID:19008950)
(PMID:20704721)
(PMID:18257070)
(PMID:16571627)
(PMID:20643356)
(PMID:20940229)		 MGI PMID:16571627 PMID:18257070 PMID:19008950 PMID:20643356 PMID:20704721 More... NCBI chr 4:90,051,994...90,080,701
Ensembl chr 4:90,051,277...90,080,635 		JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19056682) Ensembl
MGI		 PMID:19056682 GO_REF:0000107 NCBI chr13:37,344,684...37,367,215
Ensembl chr13:37,344,699...37,367,207 		JBrowse link
regulation of establishment of planar polarity involved in neural tube closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SEC24B SEC24 homolog B, COPII coat complex component involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19966784) Ensembl
MGI		 PMID:19966784 GO_REF:0000107 NCBI chr 8:112,670,529...112,762,870
Ensembl chr 8:112,670,533...112,762,858 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17806
    developmental process 6729
      anatomical structure formation involved in morphogenesis 1344
        tube formation 182
          tube closure 115
            neural tube closure 114
              anterior neural tube closure 4
              cell-cell adhesion involved in neural tube closure + 0
              establishment of planar polarity involved in neural tube closure + 16
              initiation of neural tube closure 1
              neuropore closure + 2
              planar cell polarity pathway involved in neural tube closure + 14
              progression of neural tube closure 0
Path 2
Term Annotations click to browse term
  biological_process 17806
    developmental process 6729
      anatomical structure development 6325
        tissue development 2232
          epithelium development 1385
            morphogenesis of an epithelium 589
              epithelial tube morphogenesis 404
                epithelial tube formation 169
                  embryonic epithelial tube formation 157
                    neural tube formation 134
                      primary neural tube formation 121
                        neural tube closure 114
                          anterior neural tube closure 4
                          cell-cell adhesion involved in neural tube closure + 0
                          establishment of planar polarity involved in neural tube closure + 16
                          initiation of neural tube closure 1
                          neuropore closure + 2
                          planar cell polarity pathway involved in neural tube closure + 14
                          progression of neural tube closure 0
paths to the root