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ONTOLOGY REPORT - ANNOTATIONS

Term:tube closure
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Accession:GO:0060606 term browser browse the term
Definition:Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold.


show annotations for term's descendants           Sort by:
tube closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO MGI:1857617 (MGI:3833777|PMID:19100728) RGD PMID:19100728 MGI:3833777 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
anterior neural tube closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 acts_upstream_of_or_within ISO MGI:5056374 (MGI:5050793|PMID:21515572) RGD PMID:21515572 MGI:5050793 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Folr1 folate receptor alpha involved_in ISO (MGI:3721767|PMID:17286298) RGD PMID:17286298 MGI:3721767 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G Grhl2 grainyhead-like transcription factor 2 acts_upstream_of_or_within ISO MGI:5056365 (MGI:5050793|PMID:21515572) RGD PMID:21515572 MGI:5050793 NCBI chr 7:68,400,287...68,530,269
Ensembl chr 7:68,400,477...68,530,258 		JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like acts_upstream_of_or_within ISO MGI:4124253|MGI:4128888 (MGI:6101898|PMID:26787558) RGD PMID:26787558 MGI:6101898 NCBI chr20:13,337,983...13,443,665
Ensembl chr20:13,339,692...13,443,665 		JBrowse link
anterior neuropore closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gatad2a GATA zinc finger domain containing 2A acts_upstream_of_or_within ISO (MGI:3762244|PMID:17565372) RGD PMID:17565372 MGI:3762244 NCBI chr16:19,429,578...19,520,320
Ensembl chr16:19,429,578...19,519,587 		JBrowse link
G Tfap2a transcription factor AP-2 alpha acts_upstream_of_or_within ISO MGI:1888387 (MGI:80520|PMID:8622765) RGD PMID:8622765 MGI:80520 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
establishment of planar polarity involved in neural tube closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cthrc1 collagen triple helix repeat containing 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1915838 (MGI:3814781|PMID:18606138)
GO_REF:0000107		 RGD
Ensembl		 PMID:18606138 GO_REF:0000107 MGI:3814781 NCBI chr 7:70,122,474...70,132,756
Ensembl chr 7:70,122,474...70,132,756 		JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 acts_upstream_of_or_within ISO MGI:1857642 (MGI:3814781|PMID:18606138) RGD PMID:18606138 MGI:3814781 NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378 		JBrowse link
initiation of neural tube closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm2b lysine demethylase 2B involved_in ISO (MGI:4949568|PMID:21220025) RGD PMID:21220025 MGI:4949568 NCBI chr12:33,566,530...33,701,366
Ensembl chr12:33,574,657...33,701,355 		JBrowse link
negative regulation of planar cell polarity pathway involved in neural tube closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
neural tube closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063281.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:87860 (MGI:1327082|PMID:9883720) RGD PMID:9883720 MGI:1327082 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:87859 (MGI:1327082|PMID:9883720) RGD PMID:9883720 MGI:1327082 NCBI chr13:68,673,702...68,770,846
Ensembl chr13:68,673,722...68,839,742 		JBrowse link
G Adm adrenomedullin acts_upstream_of_or_within ISO MGI:2176598 (MGI:3689296|PMID:16981008) RGD PMID:16981008 MGI:3689296 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Alx1 ALX homeobox 1 acts_upstream_of_or_within ISO MGI:1857553 (MGI:81193|PMID:8673125) RGD PMID:8673125 MGI:81193 NCBI chr 7:38,157,626...38,177,220
Ensembl chr 7:38,147,117...38,177,220 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 acts_upstream_of_or_within ISO MGI:1888997 (MGI:2149166|PMID:11504943), (MGI:893797|PMID:9216040) RGD PMID:9216040 PMID:11504943 MGI:2149166 MGI:893797 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Arhgap35 Rho GTPase activating protein 35 acts_upstream_of_or_within ISO MGI:2448591 (MGI:1926242|PMID:11044403) RGD PMID:11044403 MGI:1926242 NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298 		JBrowse link
G Arid1a AT-rich interaction domain 1A acts_upstream_of_or_within ISO MGI:5469314 (MGI:5466629|PMID:23129809) RGD PMID:23129809 MGI:5466629 NCBI chr 5:145,908,173...145,981,552
Ensembl chr 5:145,908,181...145,985,564 		JBrowse link
G Bbs4 Bardet-Biedl syndrome 4 acts_upstream_of_or_within ISO MGI:3055492 (MGI:3607949|PMID:16170314) RGD PMID:16170314 MGI:3607949 NCBI chr 8:59,731,912...59,765,408
Ensembl chr 8:59,731,912...59,765,607 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in ISS
ISO		 PMID:11163238
(MGI:1930354|PMID:11163238)		 RGD PMID:11163238 PMID:11163238 MGI:1930354, RGD:734638 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:4429763|PMID:19850029)		 Ensembl
RGD		 PMID:19850029 GO_REF:0000107 MGI:4429763 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Brd2 bromodomain containing 2 acts_upstream_of_or_within ISO MGI:3840071 (MGI:6120662|PMID:19362612) RGD PMID:19362612 MGI:6120662 NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388 		JBrowse link
G Cc2d2a coiled-coil and C2 domain containing 2A acts_upstream_of_or_within ISO MGI:5708063 (MGI:5696765|PMID:24947469) RGD PMID:24947469 MGI:5696765 NCBI chr14:67,349,004...67,435,883
Ensembl chr14:67,351,353...67,435,949 		JBrowse link
G Cdk20 cyclin-dependent kinase 20 acts_upstream_of_or_within ISO MGI:6113512 (MGI:5912686|PMID:28817564) RGD PMID:28817564 MGI:5912686 NCBI chr17:701,122...707,869
Ensembl chr17:701,124...707,826 		JBrowse link
G Cecr2 CECR2, histone acetyl-lysine reader acts_upstream_of_or_within ISO MGI:2135272|MGI:3574034|MGI:4829945 (MGI:3530173|PMID:15640247), (MGI:4822542|PMID:20589882), (MGI:4880797|PMID:21246654) RGD PMID:15640247 PMID:20589882 PMID:21246654 MGI:3530173 MGI:4822542 MGI:4880797 NCBI chr 4:153,890,310...153,998,078
Ensembl chr 4:153,890,206...153,993,451 		JBrowse link
G Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:2667273|PMID:12842012)
MGI:107926|MGI:2135272 (MGI:3703464|PMID:17229766)		 RGD PMID:12842012 PMID:17229766 MGI:2667273 MGI:3703464 NCBI chr 7:116,987,616...117,125,035
Ensembl chr 7:116,987,605...117,125,164 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 acts_upstream_of_or_within ISO MGI:2385355 (MGI:2384266|PMID:12149478) RGD PMID:12149478 MGI:2384266 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Cluap1 clusterin associated protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:5523142 (MGI:5509110|PMID:23742838)
GO_REF:0000107		 RGD
Ensembl		 PMID:23742838 GO_REF:0000107 MGI:5509110 NCBI chr10:11,587,963...11,619,711
Ensembl chr10:11,588,017...11,619,711 		JBrowse link
G Cobl cordon-bleu WH2 repeat protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2135272 (MGI:2676511|PMID:14512015)
GO_REF:0000107		 RGD
Ensembl		 PMID:14512015 GO_REF:0000107 MGI:2676511 NCBI chr14:86,828,137...87,060,682
Ensembl chr14:86,828,139...87,060,800 		JBrowse link
G Deaf1 DEAF1 transcription factor involved_in ISS
ISO		 GO_REF:0000024
(MGI:3029622|PMID:14966286)		 UniProt
RGD		 PMID:14966286 GO_REF:0000024 MGI:3029622 NCBI chr 1:196,401,857...196,435,541
Ensembl chr 1:196,401,857...196,435,541 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein acts_upstream_of_or_within ISO MGI:3529997 (MGI:3529660|PMID:15710412) RGD PMID:15710412 MGI:3529660 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 acts_upstream_of_or_within ISO MGI:2429760 (MGI:2389015|PMID:12421720) RGD PMID:12421720 MGI:2389015 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820 		JBrowse link
G Enah ENAH, actin regulator acts_upstream_of_or_within ISO MGI:109268|MGI:97549 (MGI:1331576|PMID:10069337), (MGI:3054149|PMID:15371503) RGD PMID:10069337 PMID:15371503 MGI:1331576 MGI:3054149 NCBI chr13:93,617,747...93,738,119
Ensembl chr13:93,626,944...93,740,955 		JBrowse link
G Fuz fuzzy planar cell polarity protein involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:21840926)
MGI:4346364 (MGI:4367921|PMID:19877275)
(MGI:4438317|PMID:19767740), (MGI:5296277|PMID:21840926)
GO_REF:0000024		 RGD
UniProt		 PMID:19767740 PMID:19877275 PMID:21840926 GO_REF:0000024 MGI:4367921 MGI:4438317 MGI:5296277 NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530 		JBrowse link
G Fzd3 frizzled class receptor 3 acts_upstream_of_or_within ISO MGI:108474 (MGI:3616416|PMID:16495441) RGD PMID:16495441 MGI:3616416 NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369 		JBrowse link
G Fzd6 frizzled class receptor 6 acts_upstream_of_or_within ISO MGI:108476 (MGI:3616416|PMID:16495441) RGD PMID:16495441 MGI:3616416 NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776 		JBrowse link
G Glmn glomulin, FKBP associated protein acts_upstream_of_or_within ISO MGI:3817643 (MGI:5320488|PMID:22405651) RGD PMID:22405651 MGI:5320488 NCBI chr14:2,187,144...2,231,295
Ensembl chr14:2,187,642...2,230,420 		JBrowse link
G Grhl2 grainyhead-like transcription factor 2 acts_upstream_of_or_within
involved_in		 ISO MGI:4331210 (MGI:4947318|PMID:21262862)
(MGI:4835348|PMID:20654612), (MGI:4867118|PMID:20978075)		 RGD PMID:20654612 PMID:20978075 PMID:21262862 MGI:4835348 MGI:4867118 MGI:4947318 NCBI chr 7:68,400,287...68,530,269
Ensembl chr 7:68,400,477...68,530,258 		JBrowse link
G Grhl3 grainyhead-like transcription factor 3 involved_in ISO (MGI:3689640|PMID:16949565), (MGI:4835348|PMID:20654612) RGD PMID:16949565 PMID:20654612 MGI:3689640 MGI:4835348 NCBI chr 5:147,774,161...147,806,291
Ensembl chr 5:147,774,160...147,806,160 		JBrowse link
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 acts_upstream_of_or_within
involved_in		 ISO MGI:2137552 (MGI:1267118|PMID:9636176), (MGI:3577662|PMID:15755804)
(MGI:3714713|PMID:17442300)		 RGD PMID:9636176 PMID:15755804 PMID:17442300 MGI:1267118 MGI:3577662 MGI:3714713 NCBI chr 6:69,181,429...69,268,045
Ensembl chr 6:69,181,436...69,268,053 		JBrowse link
G Ift122 intraflagellar transport 122 involved_in ISO (MGI:3827087|PMID:19000668) RGD PMID:19000668 MGI:3827087 NCBI chr 4:148,905,031...148,975,458
Ensembl chr 4:148,905,046...148,975,458 		JBrowse link
G Ift172 intraflagellar transport 172 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3829198 (MGI:3828200|PMID:18930042)
GO_REF:0000107		 RGD
Ensembl		 PMID:18930042 GO_REF:0000107 MGI:3828200 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860 		JBrowse link
G Ift57 intraflagellar transport 57 acts_upstream_of_or_within ISO MGI:3707373 (MGI:3703110|PMID:17027958) RGD PMID:17027958 MGI:3703110 NCBI chr11:51,051,520...51,124,909
Ensembl chr11:51,059,611...51,124,812 		JBrowse link
G Kat2a lysine acetyltransferase 2A acts_upstream_of_or_within ISO MGI:3711317 (MGI:3709911|PMID:17325035) RGD PMID:17325035 MGI:3709911 NCBI chr10:85,632,216...85,640,561
Ensembl chr10:85,632,216...85,640,166 		JBrowse link
G Kdm2a lysine demethylase 2A acts_upstream_of_or_within ISO (MGI:5615026|PMID:25463925) RGD PMID:25463925 MGI:5615026 NCBI chr 1:201,612,427...201,682,359
Ensembl chr 1:201,612,453...201,680,787 		JBrowse link
G Kdm6a lysine demethylase 6A acts_upstream_of_or_within ISO MGI:5448825 (MGI:5448135|PMID:22949634) RGD PMID:22949634 MGI:5448135 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062 		JBrowse link
G Kif20b kinesin family member 20B acts_upstream_of_or_within ISO MGI:3578531 (MGI:3577662|PMID:15755804) RGD PMID:15755804 MGI:3577662 NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787 		JBrowse link
G Lhx2 LIM homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1890208 (MGI:2154554|PMID:11719201)		 Ensembl
RGD		 PMID:11719201 GO_REF:0000107 MGI:2154554 NCBI chr 3:22,113,619...22,143,909
Ensembl chr 3:22,126,007...22,143,908 		JBrowse link
G Lias lipoic acid synthetase acts_upstream_of_or_within ISO MGI:3578174 (MGI:3577662|PMID:15755804) RGD PMID:15755804 MGI:3577662 NCBI chr14:42,876,699...42,893,824
Ensembl chr14:42,876,699...42,893,783 		JBrowse link
G Lmo4 LIM domain only 4 acts_upstream_of_or_within
involved_in		 ISO MGI:3035827|MGI:3574586 (MGI:3029621|PMID:14966285), (MGI:3573996|PMID:15691703)
(MGI:3689640|PMID:16949565)		 RGD PMID:14966285 PMID:15691703 PMID:16949565 MGI:3029621 MGI:3573996 MGI:3689640 NCBI chr 2:233,264,180...233,280,881
Ensembl chr 2:233,264,182...233,280,880 		JBrowse link
G Lrp2 LDL receptor related protein 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5603707|PMID:24639464)		 UniProt
Ensembl
RGD		 PMID:24639464 GO_REF:0000024 GO_REF:0000107 MGI:5603707 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:1861309|MGI:2673982|MGI:4415718|MGI:98958 (MGI:1347661|PMID:10545599), (MGI:3055483|PMID:15469977), (MGI:4413372|PMID:19795512), (MGI:4413396|PMID:19653321) RGD PMID:10545599 PMID:15469977 PMID:19653321 PMID:19795512 MGI:1347661 MGI:3055483 MGI:4413372 MGI:4413396 MGI:61254 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Med12 mediator complex subunit 12 acts_upstream_of_or_within ISO MGI:4839484 (MGI:4839483|PMID:20630950) RGD PMID:20630950 MGI:4839483 NCBI chr  X:66,404,807...66,427,775
Ensembl chr  X:66,404,760...66,428,387 		JBrowse link
G Mks1 MKS transition zone complex subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4410614|MGI:4433029 (MGI:4367169|PMID:19776033), (MGI:5487695|PMID:23454480)		 Ensembl
RGD		 PMID:19776033 PMID:23454480 GO_REF:0000107 MGI:4367169 MGI:5487695 NCBI chr10:72,655,921...72,667,007
Ensembl chr10:72,655,921...72,666,655 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO
IEA		 (MGI:5503248|PMID:23704330)
GO_REF:0000107		 RGD
Ensembl		 PMID:23704330 GO_REF:0000107 MGI:5503248 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like involved_in ISO (MGI:5468075|PMID:23267094) RGD PMID:23267094 MGI:5468075 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase acts_upstream_of ISO (PMID:25855017), (PMID:29222906) RGD PMID:25855017 PMID:29222906 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Nckap1 NCK-associated protein 1 acts_upstream_of_or_within ISO MGI:3578145 (MGI:3701029|PMID:16831833) RGD PMID:16831833 MGI:3701029 NCBI chr 3:65,417,450...65,491,769
Ensembl chr 3:65,417,453...65,492,217 		JBrowse link
G Nog noggin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856173|MGI:1862000 (MGI:3640733|PMID:16712836)		 Ensembl
RGD		 PMID:16712836 GO_REF:0000107 MGI:3640733 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3578528 (MGI:3577662|PMID:15755804)
GO_REF:0000107		 RGD
Ensembl		 PMID:15755804 GO_REF:0000107 MGI:3577662 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:84247|PMID:8951055)		 UniProt
RGD		 PMID:8951055 GO_REF:0000024 MGI:84247 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Pax3 paired box 3 acts_upstream_of_or_within ISO MGI:3043030 (MGI:3056222|PMID:15384171) RGD PMID:15384171 MGI:3056222 NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042 		JBrowse link
G Pfn1 profilin 1 acts_upstream_of_or_within ISO MGI:108360 (MGI:1331576|PMID:10069337) RGD PMID:10069337 MGI:1331576 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631 		JBrowse link
G Phactr4 phosphatase and actin regulator 4 involved_in ISO (MGI:3719969|PMID:17609112) RGD PMID:17609112 MGI:3719969 NCBI chr 5:144,549,350...144,621,259
Ensembl chr 5:144,549,363...144,620,865 		JBrowse link
G Plxnb2 plexin B2 involved_in ISO (MGI:3712712|PMID:17554007) RGD PMID:17554007 MGI:3712712 NCBI chr 7:120,232,276...120,258,385
Ensembl chr 7:120,232,331...120,258,330 		JBrowse link
G Prickle1 prickle planar cell polarity protein 1 involved_in ISO
IEA		 (PMID:21901791)
GO_REF:0000107
MGI:5645931 (MGI:5586584|PMID:25190059)		 RGD
Ensembl		 PMID:21901791 PMID:25190059 GO_REF:0000107 MGI:5586584 NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:97760 (MGI:5308523|PMID:22007132)
GO_REF:0000107		 RGD
Ensembl		 PMID:22007132 GO_REF:0000107 MGI:5308523 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:97592 (MGI:5308523|PMID:22007132)
GO_REF:0000107		 RGD
Ensembl		 PMID:22007132 GO_REF:0000107 MGI:5308523 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Ptch1 patched 1 acts_upstream_of_or_within ISO MGI:1857447 (MGI:1095757|PMID:9262482) RGD PMID:9262482 MGI:1095757 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Ptk7 protein tyrosine kinase 7 acts_upstream_of_or_within ISO MGI:2135272|MGI:3046905|MGI:3640803 (MGI:3046397|PMID:15229603), (MGI:4830023|PMID:20704721) RGD PMID:15229603 PMID:20704721 MGI:3046397 MGI:4830023 NCBI chr 9:14,352,155...14,418,473
Ensembl chr 9:14,351,202...14,418,494 		JBrowse link
G Rab23 RAB23, member RAS oncogene family acts_upstream_of_or_within
involved_in		 ISO MGI:2137533 (MGI:1267118|PMID:9636176)
(MGI:69552|PMID:7720556)		 RGD PMID:7720556 PMID:9636176 MGI:1267118 MGI:69552 NCBI chr 9:35,943,522...35,967,367
Ensembl chr 9:35,944,085...35,966,927 		JBrowse link
G Rala RAS like proto-oncogene A involved_in ISO (MGI:5504565|PMID:23063435) RGD PMID:23063435 MGI:5504565 NCBI chr17:47,092,163...47,145,192
Ensembl chr17:47,092,207...47,144,063 		JBrowse link
G Rara retinoic acid receptor, alpha acts_upstream_of_or_within ISO MGI:97858 (MGI:69060|PMID:7607067) RGD PMID:7607067 MGI:69060 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Rarg retinoic acid receptor, gamma acts_upstream_of_or_within ISO MGI:97856 (MGI:69060|PMID:7607067) RGD PMID:7607067 MGI:69060 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177 		JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a acts_upstream_of_or_within ISO MGI:3029714 (MGI:3027667|PMID:14749425) RGD PMID:14749425 MGI:3027667 NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 acts_upstream_of_or_within ISO MGI:1100883|MGI:2135272 (MGI:3703464|PMID:17229766) RGD PMID:17229766 MGI:3703464 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G Rps7 ribosomal protein S7 acts_upstream_of_or_within ISO MGI:3043039 (MGI:3056222|PMID:15384171) RGD PMID:15384171 MGI:3056222 NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145 		JBrowse link
G Sall1 spalt-like transcription factor 1 acts_upstream_of_or_within ISO MGI:2139360 (MGI:3698636|PMID:16790473) RGD PMID:16790473 MGI:3698636 NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705 		JBrowse link
G Sall4 spalt-like transcription factor 4 acts_upstream_of_or_within ISO MGI:1889585|MGI:3699175 (MGI:3698636|PMID:16790473) RGD PMID:16790473 MGI:3698636 NCBI chr 3:157,474,067...157,491,055
Ensembl chr 3:157,474,642...157,490,822 		JBrowse link
G Scrib scribble planar cell polarity protein involved_in
acts_upstream_of_or_within		 ISO (PMID:22095531)
MGI:1889322|MGI:2135272|MGI:5056373 (MGI:4819429|PMID:20643356), (MGI:5050793|PMID:21515572)		 RGD PMID:20643356 PMID:21515572 PMID:22095531 MGI:4819429 MGI:5050793 NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331 		JBrowse link
G Sdc4 syndecan 4 acts_upstream_of_or_within ISO MGI:2135272 (MGI:5498591|PMID:23760952) RGD PMID:23760952 MGI:5498591 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580 		JBrowse link
G Sec24b SEC24 homolog B, COPII coat complex component acts_upstream_of_or_within ISO MGI:2135272|MGI:4440621 (MGI:4438817|PMID:19966784), (MGI:4439427|PMID:20215345) RGD PMID:19966784 PMID:20215345 MGI:4438817 MGI:4439427 NCBI chr 2:218,562,670...218,632,753
Ensembl chr 2:218,562,676...218,632,699 		JBrowse link
G Sema4c semaphorin 4C involved_in ISO (MGI:4881530|PMID:21122816) RGD PMID:21122816 MGI:4881530 NCBI chr 9:38,791,668...38,802,171
Ensembl chr 9:38,791,670...38,802,128 		JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase acts_upstream_of_or_within ISO MGI:4437211 (MGI:4431136|PMID:20133625) RGD PMID:20133625 MGI:4431136 NCBI chr 8:110,511,808...110,597,475
Ensembl chr 8:110,511,772...110,597,489 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of_or_within ISO MGI:108078 (MGI:4429763|PMID:19850029) RGD PMID:19850029 MGI:4429763 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO MGI:892014 (MGI:4429763|PMID:19850029) RGD PMID:19850029 MGI:4429763 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Shroom3 shroom family member 3 acts_upstream_of_or_within ISO MGI:1889778 (MGI:3610718|PMID:16249236) RGD PMID:16249236 MGI:3610718 NCBI chr14:15,099,415...15,396,832
Ensembl chr14:15,099,423...15,396,915 		JBrowse link
G Ski Ski proto-oncogene acts_upstream_of_or_within ISO MGI:2177555 (MGI:1095997|PMID:9284043) RGD PMID:9284043 MGI:1095997 NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733 		JBrowse link
G Spint1 serine peptidase inhibitor, Kunitz type 1 acts_upstream_of_or_within ISO MGI:1338031|MGI:1338881 (MGI:4360135|PMID:19592578) RGD PMID:19592578 MGI:4360135 NCBI chr 3:106,231,082...106,244,121
Ensembl chr 3:106,231,444...106,244,119 		JBrowse link
G Spint2 serine peptidase inhibitor, Kunitz type, 2 acts_upstream_of_or_within ISO MGI:1338033|MGI:1338881|MGI:2156187 (MGI:4360135|PMID:19592578) RGD PMID:19592578 MGI:4360135 NCBI chr 1:84,558,159...84,580,616
Ensembl chr 1:84,558,166...84,580,616 		JBrowse link
G St14 ST14 transmembrane serine protease matriptase acts_upstream_of_or_within ISO MGI:1338031|MGI:1338033 (MGI:4360135|PMID:19592578) RGD PMID:19592578 MGI:4360135 NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517 		JBrowse link
G Stil STIL, centriolar assembly protein acts_upstream_of_or_within ISO MGI:2152962 (MGI:1339521|PMID:10385121) RGD PMID:10385121 MGI:1339521 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:3512046 (MGI:3604917|PMID:16155214) RGD PMID:16155214 MGI:3604917 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577 		JBrowse link
G Tbxt T-box transcription factor T acts_upstream_of_or_within ISO MGI:1856158 (MGI:3701028|PMID:16835439) RGD PMID:16835439 MGI:3701028 NCBI chr 1:52,298,104...52,309,813
Ensembl chr 1:52,298,099...52,305,864 		JBrowse link
G Tead2 TEA domain transcription factor 2 acts_upstream_of_or_within ISO MGI:3763367 (MGI:3763398|PMID:17868131) RGD PMID:17868131 MGI:3763398 NCBI chr 1:95,702,366...95,719,186
Ensembl chr 1:95,703,005...95,719,186 		JBrowse link
G Tfap2a transcription factor AP-2 alpha acts_upstream_of_or_within ISO MGI:2176682 (MGI:1313057|PMID:9811866), (MGI:80519|PMID:8622766) RGD PMID:8622766 PMID:9811866 MGI:1313057 MGI:80519 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (MGI:74339|PMID:7600998) RGD PMID:7600998 MGI:74339 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:894212|PMID:9217007) RGD PMID:9217007 MGI:894212 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 acts_upstream_of_or_within ISO MGI:3698004 (MGI:3697552|PMID:17082251) RGD PMID:17082251 MGI:3697552 NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:4456438 (MGI:4453264|PMID:20178780)
GO_REF:0000107		 RGD
Ensembl		 PMID:20178780 GO_REF:0000107 MGI:4453264 NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO
IEA		 (MGI:2181331|PMID:11007897)
GO_REF:0000107		 RGD
Ensembl		 PMID:11007897 GO_REF:0000107 MGI:2181331 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trim71 tripartite motif containing 71 acts_upstream_of_or_within ISO MGI:4123844 (MGI:4356244|PMID:19098426) RGD PMID:19098426 MGI:4356244 NCBI chr 8:114,193,439...114,250,807
Ensembl chr 8:114,199,187...114,250,807 		JBrowse link
G Tsc1 TSC complex subunit 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2183146 (MGI:2137425|PMID:11438694)
GO_REF:0000107		 RGD
Ensembl		 PMID:11438694 GO_REF:0000107 MGI:2137425 NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674 		JBrowse link
G Tsc2 TSC complex subunit 2 acts_upstream_of_or_within ISO MGI:1926345 (MGI:1333508|PMID:10096549) RGD PMID:10096549 MGI:1333508 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Tulp3 TUB like protein 3 acts_upstream_of_or_within ISO MGI:3664273 (MGI:3841513|PMID:19223390) RGD PMID:19223390 MGI:3841513 NCBI chr 4:161,590,478...161,632,244
Ensembl chr 4:161,590,479...161,632,149 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:1857265 (MGI:72096|PMID:7729687) RGD PMID:7729687 MGI:72096 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 acts_upstream_of_or_within ISO MGI:105056|MGI:107926|MGI:1100883|MGI:1349164|MGI:1857642|MGI:1918711|MGI:1923799|MGI:2139764|MGI:98958 (MGI:2153976|PMID:11709546), (MGI:2449213|PMID:12499390), (MGI:2676511|PMID:14512015), (MGI:3046397|PMID:15229603), (MGI:3703464|PMID:17229766), (MGI:3714704|PMID:17433286), (MGI:4438817|PMID:19966784), (MGI:4880797|PMID:21246654), (MGI:5498591|PMID:23760952) RGD PMID:11709546 PMID:12499390 PMID:14512015 PMID:15229603 PMID:17229766 More... MGI:2153976 MGI:2449213 MGI:2676511 MGI:3046397 MGI:3703464 MGI:3714704 MGI:4438817 MGI:4880797 MGI:5498591 NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378 		JBrowse link
G Vasp vasodilator-stimulated phosphoprotein involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:108360 (MGI:3054149|PMID:15371503)		 RGD PMID:15371503 PMID:21873635 MGI:3054149, RGD:13792537 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO MGI:1298218|MGI:2135272 (MGI:3714704|PMID:17433286), (MGI:4413372|PMID:19795512) RGD PMID:17433286 PMID:19795512 MGI:3714704 MGI:4413372 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 acts_upstream_of_or_within ISO MGI:2387501 (MGI:3624924|PMID:16598713) RGD PMID:16598713 MGI:3624924 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
G Zic2 Zic family member 2 acts_upstream_of_or_within ISO MGI:1862004 (MGI:3056222|PMID:15384171) RGD PMID:15384171 MGI:3056222 NCBI chr15:99,576,697...99,581,522
Ensembl chr15:99,576,697...99,581,522 		JBrowse link
G Zic5 Zic family member 5 acts_upstream_of_or_within ISO MGI:3052154 (MGI:3051968|PMID:15136147) RGD PMID:15136147 MGI:3051968 NCBI chr15:99,558,285...99,567,023
Ensembl chr15:99,560,323...99,567,035 		JBrowse link
planar cell polarity pathway involved in neural tube closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 acts_upstream_of_or_within ISO MGI:1918711|MGI:2135272 (MGI:4830023|PMID:20704721) RGD PMID:20704721 MGI:4830023 NCBI chr 7:116,987,616...117,125,035
Ensembl chr 7:116,987,605...117,125,164 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:106613 (MGI:3624185|PMID:16571627)
PMID:21873635		 RGD PMID:16571627 PMID:21873635 MGI:3624185, RGD:13792537 NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2135272|MGI:2429760|MGI:94941 (MGI:3624185|PMID:16571627)
PMID:21873635		 RGD PMID:16571627 PMID:21873635 MGI:3624185, RGD:13792537 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820 		JBrowse link
G Dvl3 dishevelled segment polarity protein 3 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2135272 (MGI:3821448|PMID:19008950)
PMID:21873635		 RGD PMID:19008950 PMID:21873635 MGI:3821448, RGD:13792537 NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462 		JBrowse link
G Fzd1 frizzled class receptor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1888513|MGI:2135272 (MGI:4837757|PMID:20940229)
GO_REF:0000107		 RGD
Ensembl		 PMID:20940229 GO_REF:0000107 MGI:4837757 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643 		JBrowse link
G Fzd2 frizzled class receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1196625|MGI:2135272 (MGI:4837757|PMID:20940229)		 Ensembl
RGD		 PMID:20940229 GO_REF:0000107 MGI:4837757 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334 		JBrowse link
G Grhl3 grainyhead-like transcription factor 3 acts_upstream_of_or_within ISO MGI:2135272 (MGI:4819429|PMID:20643356) RGD PMID:20643356 MGI:4819429 NCBI chr 5:147,774,161...147,806,291
Ensembl chr 5:147,774,160...147,806,160 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Ptk7 protein tyrosine kinase 7 acts_upstream_of_or_within ISO MGI:1100883|MGI:2135272 (MGI:4830023|PMID:20704721) RGD PMID:20704721 MGI:4830023 NCBI chr 9:14,352,155...14,418,473
Ensembl chr 9:14,351,202...14,418,494 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:108078|MGI:1860298|MGI:2135272 (MGI:3793375|PMID:18257070)		 Ensembl
RGD		 PMID:18257070 GO_REF:0000107 MGI:3793375 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO MGI:1860298|MGI:2135272|MGI:892014 (MGI:3793375|PMID:18257070) RGD PMID:18257070 MGI:3793375 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Sfrp5 secreted frizzled-related protein 5 acts_upstream_of_or_within ISO MGI:108078|MGI:2135272|MGI:892014 (MGI:3793375|PMID:18257070) RGD PMID:18257070 MGI:3793375 NCBI chr 1:241,006,762...241,011,224
Ensembl chr 1:241,006,762...241,011,224 		JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 acts_upstream_of_or_within ISO MGI:106613|MGI:108078|MGI:108100|MGI:1100883|MGI:1196625|MGI:1857642|MGI:1860298|MGI:1888513|MGI:1918711|MGI:2655333|MGI:892014 (MGI:3624185|PMID:16571627), (MGI:3793375|PMID:18257070), (MGI:3821448|PMID:19008950), (MGI:4819429|PMID:20643356), (MGI:4830023|PMID:20704721), (MGI:4837757|PMID:20940229) RGD PMID:16571627 PMID:18257070 PMID:19008950 PMID:20643356 PMID:20704721 More... MGI:3624185 MGI:3793375 MGI:3821448 MGI:4819429 MGI:4830023 MGI:4837757 NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1857617 (MGI:4830282|PMID:19056682)
GO_REF:0000107		 RGD
Ensembl		 PMID:19056682 GO_REF:0000107 MGI:4830282 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
regulation of establishment of planar polarity involved in neural tube closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sec24b SEC24 homolog B, COPII coat complex component acts_upstream_of_or_within ISO MGI:4440619|MGI:4440621 (MGI:4438817|PMID:19966784) RGD PMID:19966784 MGI:4438817 NCBI chr 2:218,562,670...218,632,753
Ensembl chr 2:218,562,676...218,632,699 		JBrowse link
semicircular canal fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (MGI:3575490|PMID:15765517) RGD PMID:15765517 MGI:3575490 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19574
    developmental process 6911
      anatomical structure formation involved in morphogenesis 1352
        tube formation 185
          tube closure 114
            anterior neural tube closure 4
            cell-cell adhesion involved in sealing an epithelial fold + 0
            closure of embryonic heart tube 0
            neural tube closure + 113
            semicircular canal fusion + 1
Path 2
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  biological_process 19574
    developmental process 6911
      anatomical structure development 6438
        multicellular organism development 5180
          tube development 1329
            tube morphogenesis 1033
              tube formation 185
                tube closure 114
                  anterior neural tube closure 4
                  cell-cell adhesion involved in sealing an epithelial fold + 0
                  closure of embryonic heart tube 0
                  neural tube closure + 113
                  semicircular canal fusion + 1
paths to the root