BMP4 (bone morphogenetic protein 4) - Rat Genome Database

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Gene: BMP4 (bone morphogenetic protein 4) Sus scrofa
Analyze
Symbol: BMP4
Name: bone morphogenetic protein 4
RGD ID: 14239951
Description: ENCODES a protein that exhibits growth factor activity (ortholog); identical protein binding (ortholog); INVOLVED IN anatomical structure formation involved in morphogenesis (ortholog); anatomical structure regression (ortholog); angiogenesis (ortholog); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; glypican signaling pathway; ASSOCIATED WITH ACTH-secreting pituitary adenoma (ortholog); Acute Otitis Media (ortholog); Alzheimer's disease (ortholog); FOUND IN cytoplasm (ortholog); extracellular region (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1183,416,134 - 183,792,417 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11183,415,989 - 183,422,888 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21203,773,963 - 203,780,310 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
ACTH-secreting pituitary adenoma  (ISO)
Acute Otitis Media  (ISO)
Alzheimer's disease  (ISO)
amenorrhea  (ISO)
Anorectal Malformations  (ISO)
APLASIA/HYPOPLASIA INVOLVING BONES OF THE LOWER LIMBS  (ISO)
atrial heart septal defect  (ISO)
Barrett's esophagus  (ISO)
breast cancer  (ISO)
Breast Neoplasms  (ISO)
CAKUT  (ISO)
CAKUT2  (ISO)
calcinosis  (ISO)
Cardiomegaly  (ISO)
cartilage disease  (ISO)
CHARGE syndrome  (ISO)
Choroidal Neovascularization  (ISO)
cleft lip  (ISO)
Colorectal Neoplasms  (ISO)
congenital diaphragmatic hernia  (ISO)
Congenital Limb Deformities  (ISO)
Cranial Nerve Injuries  (ISO)
Diaphragmatic Hernia  (ISO)
Endometrioid Carcinomas  (ISO)
epilepsy  (ISO)
esophagitis  (ISO)
Experimental Liver Cirrhosis  (ISO)
Femoral Fractures  (ISO)
Fetal Growth Retardation  (ISO)
Focal Cortical Dysplasia of Taylor  (ISO)
Fractures, Cartilage  (ISO)
genetic disease  (ISO)
Gliosis  (ISO)
granulosa cell tumor  (ISO)
Hearing Loss  (ISO)
Hyperoxia  (ISO)
Hypoxia-Ischemia, Brain  (ISO)
keratoconus  (ISO)
macular degeneration  (ISO)
melanoma  (ISO)
Multicystic Dysplastic Kidney  (ISO)
myositis ossificans  (ISO)
ocular hypertension  (ISO)
Oral Lichen Planus  (ISO)
orofacial cleft  (ISO)
orofacial cleft 11  (ISO)
ossification of the posterior longitudinal ligament of spine  (ISO)
osteoarthritis  (ISO)
Osteoarthritis, Experimental  (ISO)
otosclerosis  (ISO)
peptic esophagitis  (ISO)
progressive osseous heteroplasia  (ISO)
prolactinoma  (ISO)
prostate carcinoma  (ISO)
psoriatic arthritis  (ISO)
renal cell carcinoma  (ISO)
rheumatoid arthritis  (ISO)
Skull Fractures  (ISO)
Spinal Cord Injuries  (ISO)
strabismus  (ISO)
Stroke  (ISO)
syndromic microphthalmia  (ISO)
syndromic microphthalmia 6  (ISO)
Tibial Fractures  (ISO)
tooth agenesis  (ISO)
Tracheoesophageal Fistula  (ISO)
tuberous sclerosis  (ISO)
Vitamin A Deficiency  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anatomical structure formation involved in morphogenesis  (ISO)
anatomical structure regression  (ISO)
angiogenesis  (ISO)
anterior/posterior axis specification  (IEA,ISO)
aortic valve morphogenesis  (IEA)
apoptotic process involved in endocardial cushion morphogenesis  (ISO)
blood vessel development  (ISO)
blood vessel endothelial cell proliferation involved in sprouting angiogenesis  (IEA)
BMP signaling pathway  (ISO)
BMP signaling pathway involved in heart development  (IEA)
BMP signaling pathway involved in heart induction  (IEA)
BMP signaling pathway involved in nephric duct formation  (IEA)
BMP signaling pathway involved in renal system segmentation  (IEA)
BMP signaling pathway involved in ureter morphogenesis  (IEA)
bone development  (ISO)
brain development  (ISO)
branching involved in prostate gland morphogenesis  (IEA,ISO)
branching involved in ureteric bud morphogenesis  (IEA,ISO)
branching morphogenesis of an epithelial tube  (ISO)
bronchus development  (IEA,ISO)
bud dilation involved in lung branching  (IEA,ISO)
bud elongation involved in lung branching  (IEA,ISO)
camera-type eye development  (ISO)
camera-type eye morphogenesis  (ISO)
cardiac jelly development  (ISO)
cardiac muscle cell differentiation  (IEA)
cardiac right ventricle morphogenesis  (ISO)
cell fate commitment  (ISO)
cellular response to BMP stimulus  (ISO)
cellular response to dexamethasone stimulus  (ISO)
cellular response to growth factor stimulus  (ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to oxidative stress  (ISO)
cellular response to thyroid hormone stimulus  (ISO)
chondrocyte differentiation  (IEA)
cloacal septation  (IEA,ISO)
common-partner SMAD protein phosphorylation  (IEA)
coronary vasculature development  (IEA)
cranial suture morphogenesis  (IEA,ISO)
deltoid tuberosity development  (IEA)
dorsal/ventral neural tube patterning  (IEA,ISO)
embryonic cranial skeleton morphogenesis  (IEA,ISO)
embryonic digit morphogenesis  (IEA,ISO)
embryonic hindlimb morphogenesis  (IEA,ISO)
embryonic limb morphogenesis  (ISO)
embryonic morphogenesis  (ISO)
embryonic skeletal joint morphogenesis  (IEA,ISO)
embryonic skeletal system development  (ISO)
embryonic skeletal system morphogenesis  (ISO)
endocardial cushion development  (IEA)
endochondral ossification  (IEA)
endoderm development  (IEA,ISO)
epithelial cell proliferation involved in lung morphogenesis  (IEA,ISO)
epithelial to mesenchymal transition involved in endocardial cushion formation  (ISO)
epithelial tube branching involved in lung morphogenesis  (ISO)
epithelial-mesenchymal cell signaling  (IEA,ISO)
epithelium development  (ISO)
erythrocyte differentiation  (IEA,ISO)
eye development  (ISO)
forebrain development  (ISO)
germ cell development  (IEA,ISO)
glomerular capillary formation  (IEA)
glomerular visceral epithelial cell development  (IEA,ISO)
heart development  (ISO)
hematopoietic progenitor cell differentiation  (ISO)
inner ear receptor cell differentiation  (IEA,ISO)
intermediate mesodermal cell differentiation  (IEA)
kidney development  (ISO)
lens induction in camera-type eye  (IEA,ISO)
lung alveolus development  (IEA,ISO)
lung development  (ISO)
lung lobe development  (ISO)
lung morphogenesis  (ISO)
lymphoid progenitor cell differentiation  (IEA)
macrophage differentiation  (IEA)
mammary gland formation  (IEA,ISO)
membranous septum morphogenesis  (IEA)
mesenchymal cell differentiation involved in kidney development  (IEA)
mesenchymal cell differentiation involved in renal system development  (ISO)
mesenchymal cell proliferation involved in ureter development  (IEA,ISO)
mesenchymal cell proliferation involved in ureteric bud development  (IEA,ISO)
mesenchymal to epithelial transition involved in metanephros morphogenesis  (IEA)
mesoderm formation  (ISO)
mesodermal cell differentiation  (ISO)
mesodermal cell fate determination  (IEA,ISO)
mesonephros development  (ISO)
metanephric collecting duct development  (IEA)
metanephros development  (ISO)
monocyte differentiation  (IEA)
muscular septum morphogenesis  (ISO)
negative regulation of apoptotic process  (IBA)
negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway  (IEA)
negative regulation of branching involved in ureteric bud morphogenesis  (IEA,ISO)
negative regulation of cell cycle  (ISO)
negative regulation of cell death  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of cell proliferation involved in heart morphogenesis  (IEA)
negative regulation of chondrocyte differentiation  (IEA,ISO)
negative regulation of epithelial cell proliferation  (IEA,ISO)
negative regulation of extrinsic apoptotic signaling pathway  (IEA)
negative regulation of gene expression  (IEA,ISO)
negative regulation of glomerular mesangial cell proliferation  (IEA)
negative regulation of glomerulus development  (IEA)
negative regulation of immature T cell proliferation in thymus  (IEA)
negative regulation of MAP kinase activity  (IEA)
negative regulation of mesenchymal cell proliferation involved in ureter development  (IEA)
negative regulation of metanephric comma-shaped body morphogenesis  (IEA)
negative regulation of metanephric S-shaped body morphogenesis  (IEA)
negative regulation of mitotic nuclear division  (IEA)
negative regulation of myoblast differentiation  (IEA,ISO)
negative regulation of oligodendrocyte differentiation  (ISO)
negative regulation of phosphorylation  (ISO)
negative regulation of pri-miRNA transcription by RNA polymerase II  (IEA)
negative regulation of prostatic bud formation  (IEA,ISO)
negative regulation of striated muscle tissue development  (IEA,ISO)
negative regulation of T cell differentiation in thymus  (ISO)
negative regulation of thymocyte apoptotic process  (IEA)
negative regulation of transcription by RNA polymerase II  (IBA,ISO)
negative regulation of transcription, DNA-templated  (ISO)
neural tube closure  (IEA,ISO)
neuron fate commitment  (IEA,ISO)
odontogenesis  (ISO)
odontogenesis of dentin-containing tooth  (IEA,ISO)
organ induction  (ISO)
osteoblast differentiation  (IEA,ISO)
outflow tract morphogenesis  (ISO)
outflow tract septum morphogenesis  (IEA)
ovarian follicle development  (ISO)
pharyngeal arch artery morphogenesis  (IEA)
pituitary gland development  (IEA,ISO)
positive chemotaxis  (IEA)
positive regulation of apoptotic process  (IEA,ISO)
positive regulation of BMP signaling pathway  (IEA)
positive regulation of bone mineralization  (IEA,ISO)
positive regulation of branching involved in lung morphogenesis  (IEA)
positive regulation of branching involved in ureteric bud morphogenesis  (ISO)
positive regulation of calcium ion transport into cytosol  (ISO)
positive regulation of cardiac muscle fiber development  (IEA)
positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis  (IEA)
positive regulation of cartilage development  (IEA,ISO)
positive regulation of cell death  (ISO)
positive regulation of cell differentiation  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of cell proliferation involved in outflow tract morphogenesis  (IEA)
positive regulation of collagen biosynthetic process  (IEA)
positive regulation of endothelial cell apoptotic process  (ISO)
positive regulation of endothelial cell differentiation  (IEA)
positive regulation of endothelial cell migration  (IEA)
positive regulation of endothelial cell proliferation  (IEA)
positive regulation of epidermal cell differentiation  (IEA)
positive regulation of epithelial cell proliferation  (ISO)
positive regulation of epithelial to mesenchymal transition  (IEA)
positive regulation of ERK1 and ERK2 cascade  (IEA,ISO)
positive regulation of gene expression  (ISO)
positive regulation of hepatocyte differentiation  (ISO)
positive regulation of kidney development  (IEA)
positive regulation of MAPK cascade  (ISO)
positive regulation of mesenchymal stem cell proliferation  (ISO)
positive regulation of neuron differentiation  (IEA,ISO)
positive regulation of neuron projection development  (ISO)
positive regulation of ossification  (ISO)
positive regulation of osteoblast differentiation  (IEA,ISO)
positive regulation of p38MAPK cascade  (IEA)
positive regulation of pathway-restricted SMAD protein phosphorylation  (IBA)
positive regulation of pri-miRNA transcription by RNA polymerase II  (IEA)
positive regulation of production of miRNAs involved in gene silencing by miRNA  (IEA)
positive regulation of protein binding  (IEA,ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of SMAD protein signal transduction  (IEA)
positive regulation of smooth muscle cell proliferation  (IEA)
positive regulation of store-operated calcium channel activity  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
post-embryonic development  (IEA,ISO)
prostate gland morphogenesis  (ISO)
protein localization to nucleus  (IEA)
pulmonary artery endothelial tube morphogenesis  (IEA)
pulmonary valve morphogenesis  (IEA)
regulation of branching involved in prostate gland morphogenesis  (IEA,ISO)
regulation of cartilage development  (ISO)
regulation of cell differentiation  (ISO)
regulation of cell fate commitment  (IEA)
regulation of ERK1 and ERK2 cascade  (ISO)
regulation of gene expression  (ISO)
regulation of morphogenesis of a branching structure  (ISO)
regulation of odontogenesis of dentin-containing tooth  (IEA,ISO)
regulation of pathway-restricted SMAD protein phosphorylation  (ISO)
regulation of pri-miRNA transcription by RNA polymerase II  (ISO)
regulation of protein import into nucleus  (IEA,ISO)
regulation of smooth muscle cell differentiation  (IEA,ISO)
regulation of smooth muscle cell proliferation  (ISO)
renal system process  (IEA,ISO)
response to estradiol  (ISO)
response to glucocorticoid  (ISO)
response to mechanical stimulus  (ISO)
response to nitric oxide  (ISO)
response to organic cyclic compound  (ISO)
response to retinoic acid  (ISO)
response to testosterone  (ISO)
retina development in camera-type eye  (ISO)
secondary heart field specification  (IEA)
skeletal system development  (ISO)
SMAD protein signal transduction  (IBA,ISO)
smooth muscle cell differentiation  (ISO)
smooth muscle tissue development  (ISO)
specification of animal organ position  (IEA,ISO)
specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway  (IEA)
steroid hormone mediated signaling pathway  (IEA)
telencephalon development  (ISO)
telencephalon regionalization  (IEA,ISO)
tendon cell differentiation  (IEA)
tissue development  (ISO)
tongue morphogenesis  (ISO)
trachea development  (ISO)
trachea formation  (IEA,ISO)
type B pancreatic cell development  (IEA)
ureter epithelial cell differentiation  (IEA)
ureter smooth muscle cell differentiation  (IEA)
ureteric bud development  (ISO)
vasculature development  (ISO)
wound healing  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:19023092   PMID:19688269   PMID:24445281  


Genomics

Comparative Map Data
BMP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1183,416,134 - 183,792,417 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11183,415,989 - 183,422,888 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21203,773,963 - 203,780,310 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BMP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1453,949,736 - 53,958,761 (-)EnsemblGRCh38hg38GRCh38
GRCh381453,949,736 - 53,956,891 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371454,416,454 - 54,423,609 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361453,486,204 - 53,493,304 (-)NCBINCBI36hg18NCBI36
Build 341453,486,206 - 53,491,020NCBI
Celera1434,466,196 - 34,473,296 (-)NCBI
Cytogenetic Map14q22.2NCBI
HuRef1434,579,652 - 34,586,754 (-)NCBIHuRef
CHM1_11454,355,438 - 54,362,538 (-)NCBICHM1_1
Bmp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391446,620,982 - 46,628,126 (-)NCBIGRCm39mm39
GRCm39 Ensembl1446,620,977 - 46,628,126 (-)Ensembl
GRCm381446,383,525 - 46,390,669 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1446,383,520 - 46,390,669 (-)EnsemblGRCm38mm10GRCm38
MGSCv371447,003,195 - 47,010,274 (-)NCBIGRCm37mm9NCBIm37
MGSCv361445,305,736 - 45,309,065 (-)NCBImm8
Celera1442,555,453 - 42,562,519 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1423.95NCBI
Bmp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21519,618,538 - 19,633,494 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1519,618,542 - 19,623,306 (-)Ensembl
Rnor_6.01520,776,060 - 20,791,013 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1520,776,054 - 20,822,740 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01524,734,987 - 24,749,935 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41522,283,171 - 22,286,757 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11522,298,892 - 22,305,718 (-)NCBI
Celera1520,029,866 - 20,033,452 (-)NCBICelera
RH 3.4 Map15185.6RGD
Cytogenetic Map15p14NCBI
Bmp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554099,432,841 - 9,440,303 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554099,432,835 - 9,439,680 (+)NCBIChiLan1.0ChiLan1.0
BMP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11452,821,872 - 52,828,781 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1452,821,872 - 52,828,752 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01434,542,132 - 34,549,286 (-)NCBIMhudiblu_PPA_v0panPan3
BMP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1829,997,563 - 30,254,307 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl829,997,569 - 30,004,557 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha829,765,711 - 29,772,707 (-)NCBI
ROS_Cfam_1.0830,252,884 - 30,601,864 (-)NCBI
UMICH_Zoey_3.1829,856,480 - 29,863,475 (-)NCBI
UNSW_CanFamBas_1.0829,933,754 - 29,940,734 (-)NCBI
UU_Cfam_GSD_1.0830,299,531 - 30,306,532 (-)NCBI
Dog Cytomap8q21NCBI
Bmp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864075,280,082 - 75,287,313 (+)NCBI
SpeTri2.0NW_0049366971,054,237 - 1,061,468 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BMP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12431,097,673 - 31,104,774 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2431,097,538 - 31,101,225 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605319,326,010 - 19,333,125 (-)NCBIVero_WHO_p1.0
Bmp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473115,262,480 - 15,269,196 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 10 4 3 5 2 20 2 3 1
Below cutoff 3 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000005561   ⟹   ENSSSCP00000005423
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1183,416,134 - 183,792,417 (-)Ensembl
RefSeq Acc Id: NM_001101031   ⟹   NP_001094501
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11183,415,994 - 183,419,618 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005659968   ⟹   XP_005660025
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11183,415,989 - 183,422,884 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005659970   ⟹   XP_005660027
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11183,415,989 - 183,422,525 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069353   ⟹   XP_020925012
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11183,415,989 - 183,422,888 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069851   ⟹   XP_020925510
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11183,415,989 - 183,422,853 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_020925012   ⟸   XM_021069353
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005660025   ⟸   XM_005659968
- Peptide Label: isoform X1
- UniProtKB: A7LJT9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020925510   ⟸   XM_021069851
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005660027   ⟸   XM_005659970
- Peptide Label: isoform X1
- UniProtKB: A7LJT9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001094501   ⟸   NM_001101031
- Peptide Label: precursor
- UniProtKB: A7LJT9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000005423   ⟸   ENSSSCT00000005561
Protein Domains
TGF_BETA_2   TGFb_propeptide


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000005045 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070030602 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000005423 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070052535 UniProtKB/TrEMBL
  ENSSSCP00070052536 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000005561 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070061608 UniProtKB/TrEMBL
  ENSSSCT00070061609 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/TrEMBL
  TGF-b_C UniProtKB/TrEMBL
  TGF-b_propeptide UniProtKB/TrEMBL
  TGF-beta-rel UniProtKB/TrEMBL
  TGFb_CS UniProtKB/TrEMBL
KEGG Report ssc:100113425 UniProtKB/TrEMBL
NCBI Gene BMP4 ENTREZGENE
PANTHER PTHR11848 UniProtKB/TrEMBL
Pfam TGF_beta UniProtKB/TrEMBL
  TGFb_propeptide UniProtKB/TrEMBL
PROSITE TGF_BETA_1 UniProtKB/TrEMBL
  TGF_BETA_2 UniProtKB/TrEMBL
SMART TGFB UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/TrEMBL
UniProt A0A4X1WD52_PIG UniProtKB/TrEMBL
  A5YVW9_PIG UniProtKB/TrEMBL
  A7LJT9 ENTREZGENE, UniProtKB/TrEMBL
  A7LLU5_PIG UniProtKB/TrEMBL
VGNC ID VGNC:85843 ENTREZGENE