LOC102159820 (cadherin EGF LAG seven-pass G-type receptor 1) - Rat Genome Database

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Pathways
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Gene: LOC102159820 (cadherin EGF LAG seven-pass G-type receptor 1) Sus scrofa
Analyze
Symbol: LOC102159820 (Ensembl: CELSR1)
Name: cadherin EGF LAG seven-pass G-type receptor 1
RGD ID: 13875718
Description: ENCODES a protein that exhibits calcium ion binding (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN anterior/posterior pattern specification (ortholog); apical protein localization (ortholog); establishment of body hair planar orientation (ortholog); PARTICIPATES IN Wnt signaling, the planar cell polarity pathway; ASSOCIATED WITH genetic disease (ortholog); hereditary lymphedema (ortholog); intellectual disability (ortholog); FOUND IN membrane (inferred); nucleoplasm (inferred); plasma membrane (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila); cadherin-like protein; CELSR1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl52,980,351 - 3,203,381 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.153,114,410 - 3,203,378 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25586,808 - 596,547 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
nucleoplasm  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC102159820
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl52,980,351 - 3,203,381 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.153,114,410 - 3,203,378 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25586,808 - 596,547 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CELSR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382246,361,174 - 46,537,620 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2246,360,834 - 46,537,620 (-)EnsemblGRCh38hg38GRCh38
GRCh372246,757,071 - 46,933,517 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362245,135,395 - 45,311,731 (-)NCBINCBI36Build 36hg18NCBI36
Build 342245,077,249 - 45,253,586NCBI
Celera2230,664,148 - 30,840,512 (-)NCBICelera
Cytogenetic Map22q13.31NCBI
HuRef2229,700,771 - 29,879,343 (-)NCBIHuRef
CHM1_12246,715,504 - 46,891,675 (-)NCBICHM1_1
T2T-CHM13v2.02246,845,906 - 47,025,248 (-)NCBIT2T-CHM13v2.0
Celsr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391585,782,959 - 85,918,424 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1585,783,130 - 85,918,404 (-)EnsemblGRCm39 Ensembl
GRCm381585,898,758 - 86,034,223 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1585,898,929 - 86,034,203 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1585,898,929 - 86,033,777 (-)EnsemblGRCm38mm10GRCm38
MGSCv371585,729,188 - 85,864,207 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361585,726,695 - 85,861,543 (-)NCBIMGSCv36mm8
Celera1588,032,450 - 88,175,947 (-)NCBICelera
Cytogenetic Map15E2NCBI
cM Map1540.42NCBI
Celsr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87118,867,450 - 119,004,859 (-)NCBIGRCr8
mRatBN7.27116,987,616 - 117,125,035 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7116,987,605 - 117,125,164 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.07126,774,010 - 126,914,085 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7126,775,516 - 126,913,585 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07126,484,850 - 126,625,684 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47123,900,366 - 124,036,122 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7113,278,640 - 113,416,057 (-)NCBICelera
Cytogenetic Map7q34NCBI
Celsr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541330,457,030 - 30,561,124 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541330,455,194 - 30,561,124 (-)NCBIChiLan1.0ChiLan1.0
CELSR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22356,187,757 - 56,373,480 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12258,881,830 - 59,067,171 (-)NCBINHGRI_mPanPan1
PanPan1.12245,427,275 - 45,604,286 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2245,428,159 - 45,604,453 (-)Ensemblpanpan1.1panPan2
CELSR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11019,704,104 - 19,836,886 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1019,707,804 - 19,837,481 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1019,627,660 - 19,761,740 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01020,441,895 - 20,572,829 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1020,441,951 - 20,572,830 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11020,159,738 - 20,293,475 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01020,471,194 - 20,605,951 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01020,654,864 - 20,787,972 (+)NCBIUU_Cfam_GSD_1.0
Celsr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049453,453,384 - 3,570,250 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366293,455,887 - 3,568,566 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366293,453,384 - 3,570,250 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CELSR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11928,842,332 - 29,030,672 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1928,844,644 - 29,030,216 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604596,500,977 - 96,687,142 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Celsr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247523,425,901 - 3,535,400 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247523,426,317 - 3,537,219 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LOC102159820
2494 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 6 4 3 5 23 2 3 1
Below cutoff 4 2 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000045100   ⟹   ENSSSCP00000040901
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl52,980,351 - 3,203,381 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000047404   ⟹   ENSSSCP00000046462
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl52,980,351 - 3,200,578 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000051051   ⟹   ENSSSCP00000059338
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl52,980,351 - 3,203,381 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000066405   ⟹   ENSSSCP00000036210
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl52,980,351 - 3,203,375 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000093528   ⟹   ENSSSCP00000075673
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl52,980,550 - 3,200,904 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000094671   ⟹   ENSSSCP00000078558
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl52,980,550 - 3,200,578 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000097380   ⟹   ENSSSCP00000079697
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl52,980,550 - 3,197,083 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000100494   ⟹   ENSSSCP00000080621
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl52,980,550 - 3,200,578 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000104055   ⟹   ENSSSCP00000079135
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl52,980,550 - 3,203,375 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000105927   ⟹   ENSSSCP00000076003
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl52,980,550 - 3,200,578 (+)Ensembl
RefSeq Acc Id: XM_021091370   ⟹   XP_020947029
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.153,114,410 - 3,203,378 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020947029   ⟸   XM_021091370
- Sequence:
RefSeq Acc Id: ENSSSCP00000059338   ⟸   ENSSSCT00000051051
RefSeq Acc Id: ENSSSCP00000040901   ⟸   ENSSSCT00000045100
RefSeq Acc Id: ENSSSCP00000036210   ⟸   ENSSSCT00000066405
RefSeq Acc Id: ENSSSCP00000046462   ⟸   ENSSSCT00000047404
RefSeq Acc Id: ENSSSCP00000079135   ⟸   ENSSSCT00000104055
RefSeq Acc Id: ENSSSCP00000075673   ⟸   ENSSSCT00000093528
RefSeq Acc Id: ENSSSCP00000078558   ⟸   ENSSSCT00000094671
RefSeq Acc Id: ENSSSCP00000076003   ⟸   ENSSSCT00000105927
RefSeq Acc Id: ENSSSCP00000079697   ⟸   ENSSSCT00000097380
RefSeq Acc Id: ENSSSCP00000080621   ⟸   ENSSSCT00000100494
Protein Domains
Cadherin   EGF-like   G-protein coupled receptors family 2 profile   Laminin EGF-like   Laminin G


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000031361 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00035021314 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000045100.3 UniProtKB/TrEMBL
  ENSSSCT00000047404.2 UniProtKB/TrEMBL
  ENSSSCT00000051051.3 UniProtKB/TrEMBL
  ENSSSCT00000066405.3 UniProtKB/TrEMBL
  ENSSSCT00000093528.1 UniProtKB/TrEMBL
  ENSSSCT00000094671.1 UniProtKB/TrEMBL
  ENSSSCT00000097380.1 UniProtKB/TrEMBL
  ENSSSCT00000100494.1 UniProtKB/TrEMBL
  ENSSSCT00000104055.1 UniProtKB/TrEMBL
  ENSSSCT00000105927.1 UniProtKB/TrEMBL
  ENSSSCT00035027831.1 UniProtKB/TrEMBL
  ENSSSCT00035027857.1 UniProtKB/TrEMBL
  ENSSSCT00035027865.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.610 UniProtKB/TrEMBL
  2.60.120.200 UniProtKB/TrEMBL
  2.60.220.50 UniProtKB/TrEMBL
  4.10.1240.10 UniProtKB/TrEMBL
  Cadherins UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
  Tie2 ligand-binding domain superfamily UniProtKB/TrEMBL
InterPro Cadherin-like_dom UniProtKB/TrEMBL
  Cadherin-like_sf UniProtKB/TrEMBL
  Cadherin_CS UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  GAIN_dom_N UniProtKB/TrEMBL
  GAIN_dom_sf UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/TrEMBL
  GPCR_2_extracell_dom_sf UniProtKB/TrEMBL
  GPCR_2_extracellular_dom UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_G UniProtKB/TrEMBL
NCBI Gene LOC102159820 ENTREZGENE
PANTHER ADHESION G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  CADHERIN-89D UniProtKB/TrEMBL
  FAT ATYPICAL CADHERIN-RELATED UniProtKB/TrEMBL
  LATROPHILIN-LIKE PROTEIN LAT-2 UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/TrEMBL
  Cadherin UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
  GAIN UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  HRM UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_G_2 UniProtKB/TrEMBL
PRINTS CADHERIN UniProtKB/TrEMBL
  GPCRSECRETIN UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  CADHERIN_1 UniProtKB/TrEMBL
  CADHERIN_2 UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_LAM_1 UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_3 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  LAM_G_DOMAIN UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  EGF_Lam UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  HormR UniProtKB/TrEMBL
  LamG UniProtKB/TrEMBL
  SM00112 UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  SSF49313 UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A286ZX45_PIG UniProtKB/TrEMBL
  A0A287AA65_PIG UniProtKB/TrEMBL
  A0A287AR87_PIG UniProtKB/TrEMBL
  A0A287BSC4_PIG UniProtKB/TrEMBL
  A0A8D0Z2P1_PIG UniProtKB/TrEMBL
  A0A8D0Z356_PIG UniProtKB/TrEMBL
  A0A8D0Z588_PIG UniProtKB/TrEMBL
  A0A8W4F8S2_PIG UniProtKB/TrEMBL
  A0A8W4FCH4_PIG UniProtKB/TrEMBL
  A0A8W4FI47_PIG UniProtKB/TrEMBL
  A0A8W4FKE6_PIG UniProtKB/TrEMBL
  A0A8W4FLF6_PIG UniProtKB/TrEMBL
  A0A8W4FN43_PIG UniProtKB/TrEMBL