DVL2 (dishevelled segment polarity protein 2) - Rat Genome Database

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Gene: DVL2 (dishevelled segment polarity protein 2) Sus scrofa
Analyze
Symbol: DVL2
Name: dishevelled segment polarity protein 2
RGD ID: 14173210
Description: ENCODES a protein that exhibits frizzled binding (inferred); identical protein binding (inferred); protein domain specific binding (inferred); INVOLVED IN canonical Wnt signaling pathway (ortholog); cellular protein localization (ortholog); cochlea morphogenesis (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; Wnt signaling, non-canonical pathway; ASSOCIATED WITH common variable immunodeficiency (ortholog); dyskeratosis congenita (ortholog); very long chain acyl-CoA dehydrogenase deficiency (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: dishevelled, dsh homolog 2; LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,579,765 - 52,590,292 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,581,687 - 52,590,266 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23139,857,220 - 139,865,809 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
DVL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,579,765 - 52,590,292 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,581,687 - 52,590,266 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23139,857,220 - 139,865,809 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DVL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl177,225,342 - 7,234,517 (-)EnsemblGRCh38hg38GRCh38
GRCh38177,225,341 - 7,234,544 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37177,128,661 - 7,137,836 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,069,385 - 7,078,587 (-)NCBINCBI36hg18NCBI36
Build 34177,069,384 - 7,078,587NCBI
Celera177,153,295 - 7,162,512 (-)NCBI
Cytogenetic Map17p13.1NCBI
HuRef177,020,651 - 7,029,658 (-)NCBIHuRef
CHM1_1177,137,409 - 7,146,611 (-)NCBICHM1_1
Dvl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,891,418 - 69,900,935 (+)NCBIGRCm39mm39
GRCm39 Ensembl1169,891,421 - 69,903,127 (+)Ensembl
GRCm381170,000,592 - 70,010,109 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,000,595 - 70,012,301 (+)EnsemblGRCm38mm10GRCm38
MGSCv371169,814,128 - 69,823,611 (+)NCBIGRCm37mm9NCBIm37
MGSCv361169,816,821 - 69,826,304 (+)NCBImm8
Celera1177,548,436 - 77,558,061 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.96NCBI
Dvl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21054,723,356 - 54,732,823 (+)NCBI
Rnor_6.0 Ensembl1056,610,051 - 56,619,269 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01056,609,810 - 56,619,269 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01056,354,931 - 56,364,388 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1053,877,195 - 53,886,407 (+)NCBICelera
Cytogenetic Map10q24NCBI
Dvl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554679,675,912 - 9,683,996 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554679,675,912 - 9,683,996 (+)NCBIChiLan1.0ChiLan1.0
DVL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1177,242,493 - 7,251,572 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,242,493 - 7,251,571 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0177,255,241 - 7,264,452 (-)NCBIMhudiblu_PPA_v0panPan3
DVL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,194,326 - 32,201,922 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,194,313 - 32,201,857 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,332,631 - 32,340,205 (-)NCBI
ROS_Cfam_1.0532,299,943 - 32,307,523 (-)NCBI
UMICH_Zoey_3.1532,265,249 - 32,272,821 (-)NCBI
UNSW_CanFamBas_1.0532,224,284 - 32,231,849 (-)NCBI
UU_Cfam_GSD_1.0532,401,214 - 32,408,791 (-)NCBI
Dvl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,046,111 - 47,054,173 (-)NCBI
SpeTri2.0NW_004936595520,299 - 528,361 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DVL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,599,056 - 6,608,613 (-)NCBI
ChlSab1.1 Ensembl166,599,579 - 6,608,544 (-)Ensembl
Vero_WHO_p1.0NW_02366605914,802,139 - 14,811,719 (+)NCBI
Dvl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247869,843,580 - 9,851,538 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 9 4 3 5 2 23 2 3 3
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000028958   ⟹   ENSSSCP00000019910
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1252,579,765 - 52,590,266 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000064917   ⟹   ENSSSCP00000044243
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1252,581,690 - 52,590,292 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000084449   ⟹   ENSSSCP00000061157
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1252,581,691 - 52,589,724 (-)Ensembl
RefSeq Acc Id: XM_003354942   ⟹   XP_003354990
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11252,581,687 - 52,590,266 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003354990 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003354990   ⟸   XM_003354942
- Sequence:
RefSeq Acc Id: ENSSSCP00000044243   ⟸   ENSSSCT00000064917
RefSeq Acc Id: ENSSSCP00000061157   ⟸   ENSSSCT00000084449
RefSeq Acc Id: ENSSSCP00000019910   ⟸   ENSSSCT00000028958
Protein Domains
DEP   DIX   PDZ


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000025689 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070020923 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000019910 UniProtKB/TrEMBL
  ENSSSCP00000044243 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000061157 UniProtKB/TrEMBL
  ENSSSCP00070034910 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000028958 UniProtKB/TrEMBL
  ENSSSCT00000064917 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000084449 UniProtKB/TrEMBL
  ENSSSCT00070041578 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/TrEMBL
  3.10.20.380 UniProtKB/TrEMBL
InterPro DEP_dom UniProtKB/TrEMBL
  Dishevelled_C-dom UniProtKB/TrEMBL
  Dishevelled_fam UniProtKB/TrEMBL
  Dishevelled_protein_dom UniProtKB/TrEMBL
  DIX UniProtKB/TrEMBL
  DIX_dom_sf UniProtKB/TrEMBL
  Dsh/Dvl-rel UniProtKB/TrEMBL
  DVL2 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene DVL2 ENTREZGENE
PANTHER PTHR10878 UniProtKB/TrEMBL
  PTHR10878:SF8 UniProtKB/TrEMBL
Pfam DEP UniProtKB/TrEMBL
  Dishevelled UniProtKB/TrEMBL
  DIX UniProtKB/TrEMBL
  Dsh_C UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
PRINTS DISHEVELLED UniProtKB/TrEMBL
  DISHEVELLED2 UniProtKB/TrEMBL
PROSITE DEP UniProtKB/TrEMBL
  DIX UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
SMART DAX UniProtKB/TrEMBL
  DEP UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF50156 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A287AJQ6_PIG UniProtKB/TrEMBL
  A0A4X1V2J0_PIG UniProtKB/TrEMBL
  A0A5G2QAV6_PIG UniProtKB/TrEMBL
  I3L7A6_PIG UniProtKB/TrEMBL
VGNC ID VGNC:87491 ENTREZGENE