CITED2 (Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2) - Rat Genome Database

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Gene: CITED2 (Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2) Sus scrofa
Analyze
Symbol: CITED2
Name: Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2
RGD ID: 14079141
Description: ENCODES a protein that exhibits molecular function activator activity (ortholog); INVOLVED IN adrenal gland development (ortholog); blood vessel development (ortholog); bone morphogenesis (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH atrial heart septal defect 8 (ortholog); brain ischemia (ortholog); congenital heart disease (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cbp/p300-interacting transactivator 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,155,664 - 25,160,279 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,155,652 - 25,158,517 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2128,295,042 - 28,297,457 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adrenal cortex formation  (IEA)
adrenal gland development  (IEA,ISO)
blood vessel development  (IEA,ISO)
bone morphogenesis  (IEA,ISO)
branching involved in ureteric bud morphogenesis  (ISO)
cardiac neural crest cell development involved in heart development  (IEA,ISO)
cardiac septum morphogenesis  (IEA,ISO)
cell differentiation  (IEA)
cell population proliferation  (IEA)
cellular response to growth factor stimulus  (ISO)
cellular response to hypoxia  (IEA)
cellular senescence  (ISO)
central nervous system development  (IEA,ISO)
cranial nerve morphogenesis  (IEA,ISO)
decidualization  (IEA,ISO)
determination of heart left/right asymmetry  (IEA,ISO)
determination of left/right asymmetry in lateral mesoderm  (IEA)
determination of left/right symmetry  (IEA)
embryonic camera-type eye morphogenesis  (IEA,ISO)
embryonic heart tube left/right pattern formation  (IEA)
embryonic placenta development  (IEA,ISO)
embryonic process involved in female pregnancy  (IEA,ISO)
endocardial cushion development  (IEA,ISO)
erythrocyte development  (IEA,ISO)
granulocyte differentiation  (IEA,ISO)
heart development  (IEA)
heart looping  (IEA,ISO)
hematopoietic progenitor cell differentiation  (IEA,ISO)
in utero embryonic development  (IEA,ISO)
kidney development  (ISO)
left/right axis specification  (IEA)
left/right pattern formation  (IBA)
lens morphogenesis in camera-type eye  (IEA,ISO)
leukocyte differentiation  (IEA,ISO)
liver development  (IEA,ISO)
male gonad development  (IEA,ISO)
morphogenesis of an epithelium  (ISO)
negative regulation of apoptotic process  (IEA)
negative regulation of cardiac muscle cell proliferation  (ISO)
negative regulation of cell migration  (IEA)
negative regulation of DNA-templated transcription  (IEA)
negative regulation of gene expression  (IEA)
negative regulation of transcription by RNA polymerase II  (IEA)
neural tube closure  (IEA,ISO)
neural tube formation  (IEA,ISO)
nodal signaling pathway  (IEA)
outflow tract morphogenesis  (IEA,ISO)
peripheral nervous system development  (IEA,ISO)
positive regulation of cell cycle  (IEA)
positive regulation of cell-cell adhesion  (IEA)
positive regulation of DNA-templated transcription  (IEA)
positive regulation of gene expression  (IEA)
positive regulation of male gonad development  (IEA)
positive regulation of peroxisome proliferator activated receptor signaling pathway  (IEA)
positive regulation of transcription by RNA polymerase II  (IEA)
positive regulation of transforming growth factor beta receptor signaling pathway  (IEA)
pulmonary artery morphogenesis  (IEA,ISO)
regulation of animal organ formation  (IEA)
regulation of DNA-templated transcription  (IEA)
regulation of transcription by RNA polymerase II  (IEA,ISO)
response to estrogen  (IEA)
response to fluid shear stress  (IEA)
response to hypoxia  (IEA)
response to mechanical stimulus  (ISO)
sex determination  (IBA,IEA)
skeletal muscle cell differentiation  (IEA,ISO)
spleen development  (IEA)
thymus development  (IEA,ISO)
transforming growth factor beta receptor signaling pathway  (IEA,ISO)
trophectodermal cell differentiation  (IEA,ISO)
uterus development  (IEA,ISO)
vasculature development  (IEA,ISO)
vasculogenesis  (IEA,ISO)
ventricular septum development  (IEA,ISO)
ventricular septum morphogenesis  (IEA)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CITED2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,155,664 - 25,160,279 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,155,652 - 25,158,517 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2128,295,042 - 28,297,457 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CITED2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386139,371,807 - 139,374,648 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6139,371,807 - 139,374,648 (-)EnsemblGRCh38hg38GRCh38
GRCh376139,692,944 - 139,695,785 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366139,735,089 - 139,737,478 (-)NCBINCBI36Build 36hg18NCBI36
Build 346139,735,088 - 139,737,478NCBI
Celera6140,433,459 - 140,435,848 (-)NCBICelera
Cytogenetic Map6q24.1NCBI
HuRef6137,254,618 - 137,257,015 (-)NCBIHuRef
CHM1_16139,956,432 - 139,958,827 (-)NCBICHM1_1
T2T-CHM13v2.06140,555,711 - 140,558,549 (-)NCBIT2T-CHM13v2.0
Cited2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391017,598,452 - 17,601,422 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1017,598,966 - 17,601,422 (+)EnsemblGRCm39 Ensembl
GRCm381017,723,228 - 17,725,674 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1017,723,218 - 17,725,674 (+)EnsemblGRCm38mm10GRCm38
MGSCv371017,443,034 - 17,445,480 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361017,412,662 - 17,415,072 (+)NCBIMGSCv36mm8
Celera1017,602,360 - 17,604,805 (+)NCBICelera
Cytogenetic Map10A2NCBI
cM Map107.18NCBI
Cited2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8114,132,303 - 14,134,746 (+)NCBIGRCr8
mRatBN7.2112,312,426 - 12,314,869 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl112,312,160 - 12,314,897 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx112,084,290 - 12,086,734 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0118,086,206 - 18,088,650 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0112,292,779 - 12,295,222 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0112,823,363 - 12,825,806 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl112,823,363 - 12,825,786 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0114,515,629 - 14,518,072 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4112,721,500 - 12,723,943 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1112,721,561 - 12,724,003 (+)NCBI
Celera110,778,037 - 10,780,480 (+)NCBICelera
Cytogenetic Map1p12NCBI
Cited2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543620,370,950 - 20,372,677 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543620,370,950 - 20,372,677 (+)NCBIChiLan1.0ChiLan1.0
CITED2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25159,340,343 - 159,342,756 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16157,233,726 - 157,236,144 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06137,134,142 - 137,136,550 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16141,213,671 - 141,215,919 (-)NCBIpanpan1.1PanPan1.1panPan2
CITED2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1131,522,911 - 31,525,342 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl131,523,799 - 31,524,995 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha132,396,275 - 32,398,722 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0131,684,411 - 31,686,856 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl131,685,298 - 31,686,119 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1131,559,687 - 31,562,137 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0131,442,285 - 31,444,731 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0131,753,743 - 31,756,214 (-)NCBIUU_Cfam_GSD_1.0
Cited2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946126,574,685 - 126,577,867 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365606,354,338 - 6,356,735 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365606,353,901 - 6,356,749 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CITED2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11334,009,527 - 34,011,924 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1334,010,228 - 34,011,046 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660406,152,738 - 6,155,148 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cited2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475314,630,827 - 14,632,536 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475314,630,842 - 14,633,245 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CITED2
56 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000004577   ⟹   ENSSSCP00000004474
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl125,156,122 - 25,158,058 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000055465   ⟹   ENSSSCP00000038845
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl125,155,664 - 25,160,279 (+)Ensembl
RefSeq Acc Id: XM_001925774   ⟹   XP_001925809
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1125,155,652 - 25,158,517 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_001925809 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000004474.2
  ENSSSCP00000038845
  ENSSSCP00000038845.1
  ENSSSCP00035015688.1
  ENSSSCP00045006012.1
  ENSSSCP00065008356.1
RefSeq Acc Id: XP_001925809   ⟸   XM_001925774
- UniProtKB: A0A287A4Z1 (UniProtKB/TrEMBL),   A0A8D1GL94 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000038845   ⟸   ENSSSCT00000055465
Ensembl Acc Id: ENSSSCP00000004474   ⟸   ENSSSCT00000004577


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000004142 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00035029609 UniProtKB/TrEMBL
  ENSSSCG00045005330 UniProtKB/TrEMBL
  ENSSSCG00065015559 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000004577.3 UniProtKB/TrEMBL
  ENSSSCT00000055465 ENTREZGENE
  ENSSSCT00000055465.2 UniProtKB/TrEMBL
  ENSSSCT00035039227.1 UniProtKB/TrEMBL
  ENSSSCT00045008852.1 UniProtKB/TrEMBL
  ENSSSCT00065020632.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.2200 UniProtKB/TrEMBL
InterPro CITED UniProtKB/TrEMBL
KEGG Report ssc:100156022 UniProtKB/TrEMBL
NCBI Gene CITED2 ENTREZGENE
PANTHER CBP/P300-INTERACTING TRANSACTIVATOR 2 UniProtKB/TrEMBL
  PTHR17045 UniProtKB/TrEMBL
Pfam CITED UniProtKB/TrEMBL
UniProt A0A287A4Z1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1GL94 ENTREZGENE, UniProtKB/TrEMBL
  F1S6Z7_PIG UniProtKB/TrEMBL
VGNC ID VGNC:86712 ENTREZGENE