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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:quartz
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Accession:CHEBI:46727 term browser browse the term
Synonyms:related_synonym: Formula=O2Si;   Quarz;   Tiefquarz;   alpha-quartz;   silicon oxide
 xref: CAS:14808-60-7;   KEGG:C16459
 xref_mesh: MESH:D011791


show annotations for term's descendants           Sort by:
quartz term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 increases expression
multiple interactions		 ISO Quartz results in increased expression of ACOD1 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of ACOD1 mRNA]		 CTD PMID:32976597 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638 		JBrowse link
G ACTA2 actin alpha 2, smooth muscle multiple interactions
increases expression		 EXP
ISO		 [MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in increased expression of ACTA2 protein]; Ascorbic Acid promotes the reaction [Quartz results in increased expression of ACTA2 mRNA]; FOSL1 promotes the reaction [Quartz results in decreased expression of ACTA2 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of ACTA2 protein]
Quartz results in increased expression of ACTA2 mRNA; Quartz results in increased expression of ACTA2 protein
CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of ACTA2 protein]; Nicotine promotes the reaction [Quartz results in increased expression of ACTA2 protein]		 CTD PMID:27381660 PMID:35499148 PMID:36053221 PMID:36868510 PMID:37399107 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions		 EXP Quartz results in increased phosphorylation of AKT1 protein
FOSL1 promotes the reaction [Quartz results in increased phosphorylation of AKT1 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of AKT1 protein]; MIR34C inhibits the reaction [Quartz results in increased phosphorylation of AKT1 protein]		 CTD PMID:35499148 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G ALB albumin increases expression EXP Quartz results in increased expression of ALB protein CTD PMID:27917503 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 increases expression
decreases expression		 EXP Quartz results in increased expression of ALDH1A1 protein
Quartz results in decreased expression of ALDH1A1 mRNA		 CTD PMID:27917503 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442 		JBrowse link
G ANXA5 annexin A5 increases expression ISO Quartz results in increased expression of ANXA5 protein CTD PMID:20085295 NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995 		JBrowse link
G ANXA7 annexin A7 decreases expression EXP Quartz results in decreased expression of ANXA7 protein CTD PMID:27917503 NCBI chr10:73,375,101...73,414,058
Ensembl chr10:73,375,101...73,414,076 		JBrowse link
G ARG1 arginase 1 increases expression ISO Quartz results in increased expression of ARG1 mRNA CTD PMID:19836432 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332 		JBrowse link
G ARMCX1 armadillo repeat containing X-linked 1 decreases expression EXP Quartz results in decreased expression of ARMCX1 protein CTD PMID:27917503 NCBI chr  X:101,550,547...101,554,700
Ensembl chr  X:101,550,547...101,554,700 		JBrowse link
G ATF3 activating transcription factor 3 increases expression
multiple interactions		 EXP Quartz results in increased expression of ATF3 mRNA
ATF3 protein affects the reaction [Quartz results in increased secretion of IL1B protein]; ATF3 protein affects the reaction [Quartz results in increased secretion of IL6 protein]; ATF3 protein affects the reaction [Quartz results in increased secretion of TNF protein]		 CTD PMID:29102675 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 affects expression ISO Quartz affects the expression of ATP1B1 mRNA CTD PMID:19836432 NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992 		JBrowse link
G ATP6V1B2 ATPase H+ transporting V1 subunit B2 affects expression ISO Quartz affects the expression of ATP6V1B2 mRNA CTD PMID:19836432 NCBI chr 8:20,197,381...20,221,696
Ensembl chr 8:20,197,381...20,226,819 		JBrowse link
G AUH AU RNA binding methylglutaconyl-CoA hydratase increases expression EXP Quartz results in increased expression of AUH protein CTD PMID:27917503 NCBI chr 9:91,213,823...91,361,918
Ensembl chr 9:91,213,815...91,361,918 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions
increases expression		 EXP PSMB9 inhibits the reaction [Quartz results in increased expression of BAX protein] CTD PMID:35506645 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression		 EXP [Ascorbic Acid co-treated with Quartz] results in increased expression of BCL2 mRNA; PSMB9 inhibits the reaction [Quartz results in decreased expression of BCL2 protein] CTD PMID:27381660 PMID:35506645 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions ISO [Nicotine co-treated with Quartz] results in increased expression of BDNF protein CTD PMID:36868510 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BPIFB1 BPI fold containing family B member 1 increases expression
multiple interactions		 ISO Quartz results in increased expression of BPIFB1 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of BPIFB1 mRNA]		 CTD PMID:32976597 NCBI chr20:33,283,214...33,309,871
Ensembl chr20:33,273,480...33,309,871 		JBrowse link
G C2CD4B C2 calcium dependent domain containing 4B increases expression ISO Quartz results in increased expression of C2CD4B mRNA CTD PMID:19836432 NCBI chr15:62,163,535...62,165,285
Ensembl chr15:62,163,535...62,165,285 		JBrowse link
G C4BPA complement component 4 binding protein alpha increases expression ISO Quartz results in increased expression of C4BPA mRNA CTD PMID:19836432 NCBI chr 1:207,104,233...207,144,972
Ensembl chr 1:207,104,233...207,144,972 		JBrowse link
G CAPG capping actin protein, gelsolin like affects expression ISO Quartz affects the expression of CAPG mRNA CTD PMID:19836432 NCBI chr 2:85,391,602...85,419,540
Ensembl chr 2:85,394,753...85,418,432 		JBrowse link
G CASP12 caspase 12 (gene/pseudogene) increases expression EXP Quartz results in increased expression of CASP12 protein CTD PMID:29729927 NCBI chr11:104,883,286...104,898,460
Ensembl chr11:104,885,718...104,898,670 		JBrowse link
G CASP3 caspase 3 increases expression
multiple interactions
increases cleavage		 EXP Quartz results in increased expression of CASP3 protein
PSMB9 inhibits the reaction [Quartz results in increased cleavage of CASP3 protein]		 CTD PMID:29729927 PMID:35506645 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAT catalase multiple interactions
decreases expression		 ISO
EXP		 CAT protein inhibits the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; CAT protein inhibits the reaction [Quartz results in increased secretion of TNF protein]
Quartz results in decreased expression of CAT mRNA		 CTD PMID:19298665 PMID:27917503 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CAV1 caveolin 1 decreases expression
multiple interactions		 ISO Quartz results in decreased expression of CAV1 mRNA; Quartz results in decreased expression of CAV1 protein
CAV1 protein modified form inhibits the reaction [Quartz affects the localization of YAP1 protein]; CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of ACTA2 protein]; CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of COL1A1 protein]; CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of FN1 protein]; CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of GLS protein]; CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of YAP1 protein]		 CTD PMID:36053221 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G CCL17 C-C motif chemokine ligand 17 increases expression ISO Quartz results in increased expression of CCL17 mRNA CTD PMID:19836432 NCBI chr16:57,396,093...57,416,063
Ensembl chr16:57,404,767...57,416,063 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 increases expression
increases secretion
multiple interactions		 ISO
EXP		 Quartz results in increased expression of CCL2 mRNA
Quartz results in increased secretion of CCL2 protein
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of CCL2 mRNA]; Tobacco Smoke Pollution promotes the reaction [Quartz results in increased secretion of CCL2 protein]		 CTD PMID:19836432 PMID:27381660 PMID:32976597 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 increases expression ISO Quartz results in increased expression of CCL3 mRNA CTD PMID:19836432 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 increases expression EXP Quartz results in increased expression of CCL5 mRNA CTD PMID:27917503 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCL7 C-C motif chemokine ligand 7 increases expression
multiple interactions		 ISO Quartz results in increased expression of CCL7 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of CCL7 mRNA]		 CTD PMID:19836432 PMID:32976597 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242 		JBrowse link
G CCNA2 cyclin A2 increases expression ISO Quartz results in increased expression of CCNA2 mRNA CTD PMID:19836432 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883 		JBrowse link
G CD177 CD177 molecule multiple interactions
increases expression		 ISO Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of CD177 mRNA] CTD PMID:32976597 NCBI chr19:43,353,686...43,366,081
Ensembl chr19:43,353,686...43,363,172 		JBrowse link
G CDH1 cadherin 1 multiple interactions
decreases expression		 EXP
ISO		 [MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in decreased expression of CDH1 protein]; FOSL1 promotes the reaction [Quartz results in decreased expression of CDH1 protein]; MIR34C inhibits the reaction [Quartz results in decreased expression of CDH1 protein]
[Nicotine co-treated with Quartz] results in increased expression of CDH1 protein		 CTD PMID:35499148 PMID:36868510 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CDH2 cadherin 2 multiple interactions ISO [Nicotine co-treated with Quartz] results in increased expression of CDH2 protein; staurosporine aglycone inhibits the reaction [[Nicotine co-treated with Quartz] results in increased expression of CDH2 protein] CTD PMID:36868510 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A decreases expression EXP Quartz results in decreased expression of CDKN1A mRNA CTD PMID:27917503 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CEACAM4 CEA cell adhesion molecule 4 increases expression ISO Quartz results in increased expression of CEACAM10 mRNA CTD PMID:19836432 NCBI chr19:41,613,436...41,627,074
Ensembl chr19:41,619,015...41,627,074 		JBrowse link
G CFI complement factor I increases expression
multiple interactions		 ISO Quartz results in increased expression of CFI mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of CFI mRNA]		 CTD PMID:19836432 PMID:32976597 NCBI chr 4:109,730,982...109,801,999
Ensembl chr 4:109,731,008...109,802,150 		JBrowse link
G CH25H cholesterol 25-hydroxylase increases expression ISO Quartz results in increased expression of CH25H mRNA CTD PMID:19836432 NCBI chr10:89,205,629...89,207,317
Ensembl chr10:89,205,629...89,207,317 		JBrowse link
G CHIA chitinase acidic increases expression
multiple interactions		 ISO Quartz results in increased expression of CHIA mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of CHIA mRNA]		 CTD PMID:19836432 PMID:32976597 NCBI chr 1:111,290,851...111,320,563
Ensembl chr 1:111,290,851...111,320,566 		JBrowse link
G COL1A1 collagen type I alpha 1 chain decreases expression
multiple interactions
increases expression		 EXP
ISO		 Quartz results in decreased expression of COL1A1 mRNA
CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of COL1A1 protein]		 CTD PMID:27381660 PMID:36053221 PMID:37399107 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G COL1A2 collagen type I alpha 2 chain multiple interactions
increases expression		 ISO Nicotine promotes the reaction [Quartz results in increased expression of COL1A2 protein] CTD PMID:36868510 NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227 		JBrowse link
G CPB2 carboxypeptidase B2 increases expression ISO Quartz results in increased expression of CPB2 mRNA CTD PMID:19836432 NCBI chr13:46,053,186...46,105,033
Ensembl chr13:46,053,186...46,105,033 		JBrowse link
G CPNE5 copine 5 increases expression
multiple interactions		 ISO Quartz results in increased expression of CPNE5 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of CPNE5 mRNA]		 CTD PMID:32976597 NCBI chr 6:36,740,775...36,839,998
Ensembl chr 6:36,740,775...36,839,444 		JBrowse link
G CSF2 colony stimulating factor 2 increases expression EXP Quartz results in increased expression of CSF2 mRNA CTD PMID:27917503 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CSTF1 cleavage stimulation factor subunit 1 increases expression EXP Quartz results in increased expression of CSTF1 protein CTD PMID:27917503 NCBI chr20:56,392,379...56,406,362
Ensembl chr20:56,392,371...56,406,362 		JBrowse link
G CTSK cathepsin K increases expression ISO Quartz results in increased expression of CTSK mRNA CTD PMID:19836432 NCBI chr 1:150,796,208...150,808,260
Ensembl chr 1:150,794,880...150,809,577 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 increases expression ISO Quartz results in increased expression of CXCL1 mRNA CTD PMID:19836432 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 increases secretion
multiple interactions		 ISO Quartz results in increased secretion of CXCL10 protein
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased secretion of CXCL10 protein]		 CTD PMID:32976597 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression		 ISO [Quartz results in increased abundance of Hydrogen Peroxide] which results in increased expression of CXCL2 mRNA; Rotenone inhibits the reaction [Quartz results in increased expression of CXCL2 mRNA] CTD PMID:11764986 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 increases expression
multiple interactions		 ISO Quartz results in increased expression of CXCL5 mRNA; Quartz results in increased expression of CXCL6 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of CXCL6 mRNA]		 CTD PMID:19836432 PMID:32976597 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression
increases secretion		 EXP Quartz results in increased expression of CXCL8 mRNA
Quartz results in increased secretion of CXCL8 protein		 CTD PMID:27917503 PMID:29102675 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases expression EXP Quartz results in decreased expression of CYP1A1 mRNA CTD PMID:27917503 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 decreases expression ISO Quartz results in decreased expression of CYP2E1 mRNA CTD PMID:19836432 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression EXP Quartz results in increased expression of DDIT3 mRNA CTD PMID:27917503 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha decreases expression EXP Quartz results in decreased expression of DNMT3A mRNA CTD PMID:27917503 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta decreases expression EXP Quartz results in decreased expression of DNMT3B mRNA CTD PMID:27917503 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
G ECE1 endothelin converting enzyme 1 decreases expression EXP Quartz results in decreased expression of ECE1 mRNA CTD PMID:27917503 NCBI chr 1:21,217,250...21,345,504
Ensembl chr 1:21,217,247...21,345,572 		JBrowse link
G EDN1 endothelin 1 decreases expression EXP Quartz results in decreased expression of EDN1 mRNA CTD PMID:27917503 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDN3 endothelin 3 decreases expression EXP Quartz results in decreased expression of EDN3 mRNA CTD PMID:27917503 NCBI chr20:59,300,611...59,325,992
Ensembl chr20:59,300,443...59,325,992 		JBrowse link
G EDNRA endothelin receptor type A decreases expression EXP Quartz results in decreased expression of EDNRA mRNA CTD PMID:27917503 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954 		JBrowse link
G EGF epidermal growth factor multiple interactions
increases secretion		 ISO Tobacco Smoke Pollution promotes the reaction [Quartz results in increased secretion of EGF protein] CTD PMID:32976597 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGR1 early growth response 1 decreases expression EXP Quartz results in decreased expression of EGR1 mRNA CTD PMID:27917503 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G EPHX1 epoxide hydrolase 1 decreases expression EXP Quartz results in decreased expression of EPHX1 mRNA CTD PMID:27917503 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563 		JBrowse link
G ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit decreases expression EXP Quartz results in decreased expression of ERCC3 mRNA CTD PMID:27917503 NCBI chr 2:127,257,290...127,294,144
Ensembl chr 2:127,257,290...127,294,166 		JBrowse link
G FABP4 fatty acid binding protein 4 increases expression ISO Quartz results in increased expression of FABP4 mRNA CTD PMID:19836432 NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236 		JBrowse link
G FCGR2B Fc gamma receptor IIb increases expression ISO Quartz results in increased expression of FCGR2B mRNA CTD PMID:19836432 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654 		JBrowse link
G FGF7 fibroblast growth factor 7 increases expression
multiple interactions		 ISO Quartz results in increased expression of FGF7 protein
Nicotine promotes the reaction [Quartz results in increased expression of FGF7 protein]		 CTD PMID:36868510 NCBI chr15:49,423,242...49,488,775
Ensembl chr15:49,423,237...49,488,775 		JBrowse link
G FGG fibrinogen gamma chain increases expression ISO Quartz results in increased expression of FGG mRNA CTD PMID:19836432 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967 		JBrowse link
G FMO5 flavin containing dimethylaniline monoxygenase 5 decreases expression EXP Quartz results in decreased expression of FMO5 mRNA CTD PMID:27917503 NCBI chr 1:147,184,305...147,227,284
Ensembl chr 1:147,175,351...147,243,050 		JBrowse link
G FN1 fibronectin 1 multiple interactions
increases expression		 EXP
ISO		 [Ascorbic Acid co-treated with Quartz] results in increased expression of FN1 mRNA
Quartz results in increased expression of FN1 mRNA; Quartz results in increased expression of FN1 protein
CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of FN1 protein]; Nicotine promotes the reaction [Quartz results in increased expression of FN1 protein]		 CTD PMID:27381660 PMID:36053221 PMID:36477571 PMID:36868510 PMID:37399107 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Quartz results in increased expression of [JUN protein binds to FOS protein] CTD PMID:37399107 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit increases expression
multiple interactions		 EXP Quartz results in increased expression of FOSL1 mRNA; Quartz results in increased expression of FOSL1 protein
[MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in decreased expression of CDH1 protein]; [MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in increased expression of ACTA2 protein]; [MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in increased expression of VIM protein]; FOSL1 promotes the reaction [Quartz results in decreased expression of ACTA2 protein]; FOSL1 promotes the reaction [Quartz results in decreased expression of CDH1 protein]; FOSL1 promotes the reaction [Quartz results in decreased expression of PTEN protein]; FOSL1 promotes the reaction [Quartz results in decreased expression of TP53 protein]; FOSL1 promotes the reaction [Quartz results in increased expression of SNAI2 protein]; FOSL1 promotes the reaction [Quartz results in increased expression of VIM protein]; FOSL1 promotes the reaction [Quartz results in increased phosphorylation of AKT1 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of FOSL1 mRNA]; MIR34C inhibits the reaction [Quartz results in increased expression of FOSL1 protein]		 CTD PMID:35499148 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573 		JBrowse link
G FSCN1 fascin actin-bundling protein 1 affects expression EXP Quartz affects the expression of FSCN1 protein CTD PMID:27917503 NCBI chr 7:5,592,816...5,606,655
Ensembl chr 7:5,592,816...5,606,655 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase multiple interactions
decreases activity		 ISO Glutathione inhibits the reaction [Quartz results in decreased activity of G6PDX protein] CTD PMID:18370412 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression EXP Quartz results in increased expression of GADD45A mRNA CTD PMID:27917503 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GLRX3 glutaredoxin 3 decreases expression EXP Quartz results in decreased expression of GLRX3 protein CTD PMID:27917503 NCBI chr10:130,136,391...130,180,377
Ensembl chr10:130,136,391...130,184,521 		JBrowse link
G GLS glutaminase affects expression
multiple interactions		 ISO Quartz affects the expression of GLS protein
CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of GLS protein]		 CTD PMID:36053221 NCBI chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552 		JBrowse link
G GSDMD gasdermin D multiple interactions ISO GSDMD promotes the reaction [Quartz results in increased secretion of IL1A protein] CTD PMID:36840754 NCBI chr 8:143,553,387...143,563,062
Ensembl chr 8:143,553,207...143,563,062 		JBrowse link
G GSR glutathione-disulfide reductase decreases expression EXP Quartz results in decreased expression of GSR mRNA CTD PMID:27917503 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G HAPLN4 hyaluronan and proteoglycan link protein 4 affects expression ISO Quartz affects the expression of HAPLN4 mRNA CTD PMID:19836432 NCBI chr19:19,254,756...19,262,804
Ensembl chr19:19,254,756...19,262,804 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases expression		 ISO Quartz promotes the reaction [Curcumin results in increased expression of HMOX1 mRNA]
Quartz results in increased expression of HMOX1 mRNA		 CTD PMID:18001810 PMID:19836432 PMID:21171611 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HNRNPAB heterogeneous nuclear ribonucleoprotein A/B increases expression EXP Quartz results in increased expression of HNRNPAB protein CTD PMID:27917503 NCBI chr 5:178,204,533...178,211,163
Ensembl chr 5:178,204,533...178,211,163 		JBrowse link
G HNRNPK heterogeneous nuclear ribonucleoprotein K increases expression EXP Quartz results in increased expression of HNRNPK protein CTD PMID:27917503 NCBI chr 9:83,968,083...83,980,615
Ensembl chr 9:83,968,083...83,980,631 		JBrowse link
G HP haptoglobin increases expression ISO Quartz results in increased expression of HP mRNA CTD PMID:19836432 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A increases expression EXP Quartz results in increased expression of HSPA1A mRNA CTD PMID:27917503 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA2 heat shock protein family A (Hsp70) member 2 decreases expression EXP Quartz results in decreased expression of HSPA2 mRNA; Quartz results in decreased expression of HSPA2 protein CTD PMID:27917503 NCBI chr14:64,535,905...64,543,237
Ensembl chr14:64,535,905...64,546,173 		JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 increases expression EXP Quartz results in increased expression of HSPA6 mRNA CTD PMID:27917503 NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 increases expression EXP Quartz results in increased expression of HSPD1 protein CTD PMID:27917503 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G HTRA2 HtrA serine peptidase 2 increases expression EXP Quartz results in increased expression of HTRA2 protein CTD PMID:27917503 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 increases expression EXP Quartz results in increased expression of ICAM1 mRNA CTD PMID:27381660 PMID:27917503 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IFNG interferon gamma multiple interactions ISO
EXP		 IFNG protein promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; IFNG protein promotes the reaction [Quartz results in increased secretion of TNF protein]
Quartz results in increased expression of and results in increased secretion of IFNG protein		 CTD PMID:19298665 PMID:29729927 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL18 interleukin 18 multiple interactions
increases secretion		 ISO Tobacco Smoke Pollution promotes the reaction [Quartz results in increased secretion of IL18 protein] CTD PMID:32976597 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1A interleukin 1 alpha increases expression
multiple interactions
increases import		 ISO Quartz results in increased expression of IL1A mRNA
Cytochalasin D inhibits the reaction [Quartz results in increased import of IL1A protein]; Cytochalasin D promotes the reaction [Quartz results in increased secretion of IL1A protein]; GSDMD promotes the reaction [Quartz results in increased secretion of IL1A protein]; N-(4-(N-(3-methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide inhibits the reaction [Quartz results in increased secretion of IL1A protein]; Quartz results in increased expression of and results in increased secretion of IL1A protein		 CTD PMID:36840754 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta increases secretion
decreases expression
multiple interactions		 EXP Quartz results in increased secretion of IL1B protein
Quartz results in decreased expression of IL1B mRNA
ATF3 protein affects the reaction [Quartz results in increased secretion of IL1B protein]		 CTD PMID:19697923 PMID:27917503 PMID:29102675 PMID:35499148 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 increases expression ISO Quartz results in increased expression of IL1R2 mRNA CTD PMID:19836432 NCBI chr 2:101,991,960...102,028,544
Ensembl chr 2:101,991,960...102,028,544 		JBrowse link
G IL1RL1 interleukin 1 receptor like 1 increases expression ISO Quartz results in increased expression of IL1RL1 mRNA; Quartz results in increased expression of IL1RL1 protein CTD PMID:37399107 NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037 		JBrowse link
G IL33 interleukin 33 multiple interactions ISO [Nicotine co-treated with Quartz] results in increased expression of IL33 protein; Quartz results in increased expression of and results in increased secretion of IL33 protein CTD PMID:36868510 PMID:37399107 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G IL6 interleukin 6 multiple interactions
increases secretion
increases expression		 EXP
ISO		 ATF3 protein affects the reaction [Quartz results in increased secretion of IL6 protein]; Quartz results in increased expression of and results in increased secretion of IL6 protein
Quartz results in increased expression of IL6 mRNA		 CTD PMID:29102675 PMID:29729927 PMID:36477571 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G ITGAM integrin subunit alpha M increases expression ISO Quartz results in increased expression of ITGAM mRNA CTD PMID:19836432 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 increases expression ISO Quartz results in increased expression of ITIH1 mRNA CTD PMID:19836432 NCBI chr 3:52,777,599...52,792,068
Ensembl chr 3:52,777,595...52,792,068 		JBrowse link
G JARID2 jumonji and AT-rich interaction domain containing 2 decreases expression EXP Quartz results in decreased expression of JARID2 protein CTD PMID:27917503 NCBI chr 6:15,246,069...15,522,042
Ensembl chr 6:15,246,069...15,522,042 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Quartz results in increased expression of [JUN protein binds to FOS protein] CTD PMID:37399107 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G KNG1 kininogen 1 increases expression
multiple interactions		 ISO Quartz results in increased expression of KNG1 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of KNG1 mRNA]		 CTD PMID:32976597 NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410 		JBrowse link
G KRT18 keratin 18 decreases expression EXP Quartz results in decreased expression of KRT18 protein CTD PMID:27917503 NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906 		JBrowse link
G KRT7 keratin 7 increases expression EXP Quartz results in increased expression of KRT7 protein CTD PMID:27917503 NCBI chr12:52,233,243...52,255,853
Ensembl chr12:52,232,520...52,252,186 		JBrowse link
G LCN2 lipocalin 2 increases expression ISO Quartz results in increased expression of LCN2 mRNA CTD PMID:19836432 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G LDHA lactate dehydrogenase A multiple interactions ISO Cytochalasin D inhibits the reaction [Quartz results in increased activity of and results in increased secretion of LDHA protein]; Quartz results in increased activity of and results in increased secretion of LDHA protein CTD PMID:36840754 NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425 		JBrowse link
G LPO lactoperoxidase multiple interactions
increases expression		 ISO Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of LPO mRNA] CTD PMID:32976597 NCBI chr17:58,238,584...58,268,518
Ensembl chr17:58,218,548...58,268,518 		JBrowse link
G MAL2 mal, T cell differentiation protein 2 affects expression ISO Quartz affects the expression of MAL2 mRNA CTD PMID:19836432 NCBI chr 8:119,208,363...119,245,673
Ensembl chr 8:119,165,034...119,245,673 		JBrowse link
G MIR101-1 microRNA 101-1 decreases expression ISO Quartz results in decreased expression of MIR101A mRNA CTD PMID:23208435 NCBI chr 1:65,058,434...65,058,508
Ensembl chr 1:65,058,434...65,058,508 		JBrowse link
G MIR126 microRNA 126 decreases expression ISO Quartz results in decreased expression of MIR126A mRNA CTD PMID:23208435 NCBI chr 9:136,670,602...136,670,686
Ensembl chr 9:136,670,602...136,670,686 		JBrowse link
G MIR138-1 microRNA 138-1 increases expression ISO Quartz results in increased expression of MIR138-1 mRNA CTD PMID:23208435 NCBI chr 3:44,114,212...44,114,310
Ensembl chr 3:44,114,212...44,114,310 		JBrowse link
G MIR140 microRNA 140 decreases expression ISO Quartz results in decreased expression of MIR140 mRNA CTD PMID:23208435 NCBI chr16:69,933,081...69,933,180
Ensembl chr16:69,933,081...69,933,180 		JBrowse link
G MIR141 microRNA 141 increases expression ISO Quartz results in increased expression of MIR141 mRNA CTD PMID:23208435 NCBI chr12:6,964,097...6,964,191
Ensembl chr12:6,964,097...6,964,191 		JBrowse link
G MIR144 microRNA 144 decreases expression ISO Quartz results in decreased expression of MIR144 mRNA CTD PMID:23208435 NCBI chr17:28,861,533...28,861,618
Ensembl chr17:28,861,533...28,861,618 		JBrowse link
G MIR145 microRNA 145 decreases expression ISO Quartz results in decreased expression of MIR145 mRNA CTD PMID:23208435 NCBI chr 5:149,430,646...149,430,733
Ensembl chr 5:149,430,646...149,430,733 		JBrowse link
G MIR146A microRNA 146a increases expression ISO Quartz results in increased expression of MIR146A mRNA CTD PMID:23208435 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450 		JBrowse link
G MIR146B microRNA 146b increases expression ISO Quartz results in increased expression of MIR146B mRNA CTD PMID:23208435 NCBI chr10:102,436,512...102,436,584
Ensembl chr10:102,436,512...102,436,584 		JBrowse link
G MIR17 microRNA 17 increases expression ISO Quartz results in increased expression of MIR17 mRNA CTD PMID:23208435 NCBI chr13:91,350,605...91,350,688
Ensembl chr13:91,350,605...91,350,688 		JBrowse link
G MIR183 microRNA 183 increases expression ISO Quartz results in increased expression of MIR183 mRNA CTD PMID:23208435 NCBI chr 7:129,774,905...129,775,014
Ensembl chr 7:129,774,905...129,775,014 		JBrowse link
G MIR200B microRNA 200b decreases expression ISO Quartz results in decreased expression of MIR200B mRNA CTD PMID:23208435 NCBI chr 1:1,167,104...1,167,198
Ensembl chr 1:1,167,104...1,167,198 		JBrowse link
G MIR204 microRNA 204 increases expression ISO Quartz results in increased expression of MIR204 mRNA CTD PMID:23208435 NCBI chr 9:70,809,975...70,810,084
Ensembl chr 9:70,809,975...70,810,084 		JBrowse link
G MIR22 microRNA 22 increases expression ISO Quartz results in increased expression of MIR22 mRNA CTD PMID:23208435 NCBI chr17:1,713,903...1,713,987
Ensembl chr17:1,713,903...1,713,987 		JBrowse link
G MIR25 microRNA 25 decreases expression ISO Quartz results in decreased expression of MIR25 mRNA CTD PMID:23208435 NCBI chr 7:100,093,560...100,093,643
Ensembl chr 7:100,093,560...100,093,643 		JBrowse link
G MIR26A1 microRNA 26a-1 decreases expression ISO Quartz results in decreased expression of MIR26A mRNA CTD PMID:23208435 NCBI chr 3:37,969,404...37,969,480
Ensembl chr 3:37,969,404...37,969,480 		JBrowse link
G MIR26B microRNA 26b decreases expression ISO Quartz results in decreased expression of MIR26B mRNA CTD PMID:23208435 NCBI chr 2:218,402,646...218,402,722
Ensembl chr 2:218,402,646...218,402,722 		JBrowse link
G MIR28 microRNA 28 decreases expression ISO Quartz results in decreased expression of MIR28 mRNA CTD PMID:23208435 NCBI chr 3:188,688,781...188,688,866
Ensembl chr 3:188,688,781...188,688,866 		JBrowse link
G MIR299 microRNA 299 increases expression ISO Quartz results in increased expression of MIR299 mRNA CTD PMID:23208435 NCBI chr14:101,023,794...101,023,856
Ensembl chr14:101,023,794...101,023,856 		JBrowse link
G MIR300 microRNA 300 increases expression ISO Quartz results in increased expression of MIR300 mRNA CTD PMID:23208435 NCBI chr14:101,041,363...101,041,445
Ensembl chr14:101,041,363...101,041,445 		JBrowse link
G MIR30A microRNA 30a decreases expression ISO Quartz results in decreased expression of MIR30A mRNA CTD PMID:23208435 NCBI chr 6:71,403,551...71,403,621
Ensembl chr 6:71,403,551...71,403,621 		JBrowse link
G MIR30D microRNA 30d decreases expression ISO Quartz results in decreased expression of MIR30D mRNA CTD PMID:23208435 NCBI chr 8:134,804,876...134,804,945
Ensembl chr 8:134,804,876...134,804,945 		JBrowse link
G MIR30E microRNA 30e decreases expression ISO Quartz results in decreased expression of MIR30E mRNA CTD PMID:23208435 NCBI chr 1:40,754,355...40,754,446
Ensembl chr 1:40,754,355...40,754,446 		JBrowse link
G MIR345 microRNA 345 decreases expression ISO Quartz results in decreased expression of MIR345 mRNA CTD PMID:23208435 NCBI chr14:100,307,859...100,307,956
Ensembl chr14:100,307,859...100,307,956 		JBrowse link
G MIR34C microRNA 34c multiple interactions
decreases expression		 EXP [MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in decreased expression of CDH1 protein]; [MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in increased expression of ACTA2 protein]; [MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in increased expression of VIM protein]; MIR34C inhibits the reaction [Quartz results in decreased expression of CDH1 protein]; MIR34C inhibits the reaction [Quartz results in decreased expression of PTEN protein]; MIR34C inhibits the reaction [Quartz results in decreased expression of TP53 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of ACTA2 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of AKT1 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of FOSL1 mRNA]; MIR34C inhibits the reaction [Quartz results in increased expression of FOSL1 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of SNAI2 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of VIM protein]; MIR34C inhibits the reaction [Quartz results in increased phosphorylation of AKT1 protein]
Quartz results in decreased expression of MIR34C		 CTD PMID:35499148 NCBI chr11:111,513,439...111,513,515
Ensembl chr11:111,513,439...111,513,515 		JBrowse link
G MIR375 microRNA 375 decreases expression ISO Quartz results in decreased expression of MIR375 mRNA CTD PMID:23208435 NCBI chr 2:219,001,645...219,001,708
Ensembl chr 2:219,001,645...219,001,708 		JBrowse link
G MIR424 microRNA 424 decreases expression ISO Quartz results in decreased expression of MIR322 mRNA CTD PMID:23208435 NCBI chr  X:134,546,614...134,546,711
Ensembl chr  X:134,546,614...134,546,711 		JBrowse link
G MIR96 microRNA 96 increases expression ISO Quartz results in increased expression of MIR96 mRNA CTD PMID:23208435 NCBI chr 7:129,774,692...129,774,769
Ensembl chr 7:129,774,692...129,774,769 		JBrowse link
G MIR98 microRNA 98 decreases expression ISO Quartz results in decreased expression of MIR98 mRNA CTD PMID:23208435 NCBI chr  X:53,556,223...53,556,341
Ensembl chr  X:53,556,223...53,556,341 		JBrowse link
G MIR99A microRNA 99a decreases expression ISO Quartz results in decreased expression of MIR99A mRNA CTD PMID:23208435 NCBI chr21:16,539,089...16,539,169
Ensembl chr21:16,539,089...16,539,169 		JBrowse link
G MIRLET7D microRNA let-7d decreases expression ISO Quartz results in decreased expression of MIRLET7D mRNA CTD PMID:23208435 NCBI chr 9:94,178,834...94,178,920
Ensembl chr 9:94,178,834...94,178,920 		JBrowse link
G MKI67 marker of proliferation Ki-67 multiple interactions ISO [Nicotine co-treated with Quartz] results in increased expression of MKI67 protein CTD PMID:36868510 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G MMP1 matrix metallopeptidase 1 increases expression EXP Quartz results in increased expression of MMP1 mRNA CTD PMID:27381660 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP12 matrix metallopeptidase 12 increases expression
multiple interactions		 ISO Quartz results in increased expression of MMP12 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of MMP12 mRNA]		 CTD PMID:19836432 PMID:32976597 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982 		JBrowse link
G MSR1 macrophage scavenger receptor 1 increases expression ISO Quartz results in increased expression of MSR1 mRNA CTD PMID:19836432 NCBI chr 8:16,107,881...16,192,651
Ensembl chr 8:16,107,878...16,567,490 		JBrowse link
G MT1A metallothionein 1A decreases expression EXP Quartz results in decreased expression of MT1A mRNA CTD PMID:27917503 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor increases expression EXP Quartz results in increased expression of MYC mRNA CTD PMID:27917503 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G NFAT5 nuclear factor of activated T cells 5 increases expression EXP Quartz results in increased expression of NFAT5 mRNA CTD PMID:27917503 NCBI chr16:69,565,966...69,704,654
Ensembl chr16:69,565,094...69,704,666 		JBrowse link
G NOXO1 NADPH oxidase organizer 1 increases expression ISO Quartz results in increased expression of NOXO1 mRNA CTD PMID:19836432 NCBI chr16:1,978,917...1,981,469
Ensembl chr16:1,978,917...1,984,192 		JBrowse link
G NPM1 nucleophosmin 1 affects response to substance ISO NPM1 affects the susceptibility to Quartz CTD PMID:37399107 NCBI chr 5:171,387,116...171,410,900
Ensembl chr 5:171,387,116...171,411,810 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO [Nicotine co-treated with Quartz] results in increased phosphorylation of NTRK2 protein; staurosporine aglycone inhibits the reaction [[Nicotine co-treated with Quartz] results in increased expression of NTRK2 protein] CTD PMID:36868510 NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase decreases expression EXP Quartz results in decreased expression of OGG1 mRNA CTD PMID:27917503 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G ORM1 orosomucoid 1 multiple interactions
increases expression		 ISO Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of ORM1 mRNA] CTD PMID:32976597 NCBI chr 9:114,323,098...114,326,479
Ensembl chr 9:114,323,098...114,326,479 		JBrowse link
G PDHB pyruvate dehydrogenase E1 subunit beta increases expression
decreases expression		 EXP Quartz results in increased expression of PDHB protein
Quartz results in decreased expression of PDHB mRNA		 CTD PMID:27917503 NCBI chr 3:58,427,630...58,433,832
Ensembl chr 3:58,427,630...58,433,857 		JBrowse link
G PGK1 phosphoglycerate kinase 1 decreases expression EXP Quartz results in decreased expression of PGK1 protein CTD PMID:27917503 NCBI chr  X:78,104,248...78,129,295
Ensembl chr  X:77,910,739...78,129,295 		JBrowse link
G PKM pyruvate kinase M1/2 affects expression EXP Quartz affects the expression of PKM protein CTD PMID:27917503 NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor affects expression ISO Quartz affects the expression of PLAUR mRNA CTD PMID:19836432 NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547 		JBrowse link
G PNMA6A PNMA family member 6A increases expression EXP Quartz results in increased expression of PNMA6A protein CTD PMID:27917503 NCBI chr  X:153,072,454...153,075,019
Ensembl chr  X:153,072,454...153,075,019 		JBrowse link
G PRDX1 peroxiredoxin 1 increases expression EXP Quartz results in increased expression of PRDX1 mRNA CTD PMID:27917503 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732 		JBrowse link
G PRDX2 peroxiredoxin 2 decreases expression EXP Quartz results in decreased expression of PRDX2 mRNA CTD PMID:27917503 NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800 		JBrowse link
G PRDX5 peroxiredoxin 5 affects expression ISO Quartz affects the expression of PRDX5 mRNA CTD PMID:19836432 NCBI chr11:64,318,121...64,321,811
Ensembl chr11:64,318,121...64,321,811 		JBrowse link
G PRDX6 peroxiredoxin 6 decreases expression EXP Quartz results in decreased expression of PRDX6 protein CTD PMID:27917503 NCBI chr 1:173,477,335...173,488,815
Ensembl chr 1:173,477,330...173,488,815 		JBrowse link
G PSMB9 proteasome 20S subunit beta 9 decreases expression
multiple interactions		 ISO
EXP		 Quartz results in decreased expression of PSMB9 mRNA
Quartz results in decreased expression of PSMB9 mRNA; Quartz results in decreased expression of PSMB9 protein; Quartz results in decreased expression of PSMB9 SNP
PSMB9 inhibits the reaction [Quartz results in decreased expression of BCL2 protein]; PSMB9 inhibits the reaction [Quartz results in increased cleavage of CASP3 protein]; PSMB9 inhibits the reaction [Quartz results in increased expression of BAX protein]		 CTD PMID:35506645 NCBI chr 6:32,854,192...32,859,851
Ensembl chr 6:32,844,136...32,859,851 		JBrowse link
G PTEN phosphatase and tensin homolog multiple interactions
decreases expression		 EXP FOSL1 promotes the reaction [Quartz results in decreased expression of PTEN protein]; MIR34C inhibits the reaction [Quartz results in decreased expression of PTEN protein] CTD PMID:35499148 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 decreases expression EXP Quartz results in decreased expression of PTGS1 mRNA CTD PMID:27917503 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression		 ISO [Quartz co-treated with Ascorbic Acid] results in increased expression of PTGS2 protein; Curcumin inhibits the reaction [Quartz results in increased expression of PTGS2 mRNA]
Quartz results in increased expression of PTGS2 mRNA; Quartz results in increased expression of PTGS2 protein
[Quartz co-treated with Ascorbic Acid] results in increased expression of PTGS2 mRNA; [Quartz co-treated with Ascorbic Acid] results in increased expression of PTGS2 protein		 CTD PMID:17222177 PMID:18001810 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RBM4 RNA binding motif protein 4 increases expression EXP Quartz results in increased expression of RBM4 protein CTD PMID:27917503 NCBI chr11:66,638,703...66,668,380
Ensembl chr11:66,638,667...66,668,374 		JBrowse link
G S100A9 S100 calcium binding protein A9 increases expression ISO Quartz results in increased expression of S100A9 mRNA CTD PMID:19836432 NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 increases expression
multiple interactions		 ISO Quartz results in increased expression of SCN10A mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of SCN10A mRNA]		 CTD PMID:32976597 NCBI chr 3:38,696,807...38,816,217
Ensembl chr 3:38,696,802...38,816,286 		JBrowse link
G SDF2L1 stromal cell derived factor 2 like 1 affects expression ISO Quartz affects the expression of SDF2L1 mRNA CTD PMID:19836432 NCBI chr22:21,642,302...21,644,299
Ensembl chr22:21,642,302...21,644,299 		JBrowse link
G SEC13 SEC13 homolog, nuclear pore and COPII coat complex component affects expression EXP Quartz affects the expression of SEC13 protein CTD PMID:27917503 NCBI chr 3:10,300,931...10,321,112
Ensembl chr 3:10,293,131...10,321,112 		JBrowse link
G SEMG1 semenogelin 1 increases expression EXP Quartz results in increased expression of SEMG1 mRNA CTD PMID:27917503 NCBI chr20:45,207,033...45,209,768
Ensembl chr20:45,207,033...45,209,768 		JBrowse link
G SERPINA10 serpin family A member 10 increases expression ISO Quartz results in increased expression of SERPINA10 mRNA CTD PMID:19836432 NCBI chr14:94,280,460...94,293,268
Ensembl chr14:94,280,460...94,293,268 		JBrowse link
G SFTPC surfactant protein C multiple interactions ISO [Nicotine co-treated with Quartz] results in increased expression of SFTPC protein CTD PMID:36868510 NCBI chr 8:22,157,383...22,164,479
Ensembl chr 8:22,156,913...22,164,479 		JBrowse link
G SLC26A4 solute carrier family 26 member 4 increases expression
multiple interactions		 ISO Quartz results in increased expression of SLC26A4 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of SLC26A4 mRNA]		 CTD PMID:19836432 PMID:32976597 NCBI chr 7:107,660,828...107,717,809
Ensembl chr 7:107,660,828...107,717,809 		JBrowse link
G SNAI1 snail family transcriptional repressor 1 increases expression ISO Quartz results in increased expression of SNAI1 protein CTD PMID:36868510 NCBI chr20:49,982,980...49,988,886
Ensembl chr20:49,982,980...49,988,886 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 multiple interactions
increases expression		 EXP FOSL1 promotes the reaction [Quartz results in increased expression of SNAI2 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of SNAI2 protein] CTD PMID:35499148 NCBI chr 8:48,917,598...48,921,429
Ensembl chr 8:48,917,598...48,921,740 		JBrowse link
G SOD2 superoxide dismutase 2 increases expression ISO Quartz results in increased expression of SOD2 mRNA CTD PMID:19836432 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SPP1 secreted phosphoprotein 1 increases expression
multiple interactions		 ISO Quartz results in increased expression of SPP1 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of SPP1 mRNA]		 CTD PMID:19836432 PMID:32976597 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions
decreases phosphorylation		 ISO Nicotine inhibits the reaction [Quartz results in decreased phosphorylation of STAT3 protein]; staurosporine aglycone inhibits the reaction [[Nicotine co-treated with Quartz] results in increased phosphorylation of STAT3 protein] CTD PMID:36868510 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G TCP1 t-complex 1 affects expression EXP Quartz affects the expression of TCP1 protein CTD PMID:27917503 NCBI chr 6:159,778,498...159,789,602
Ensembl chr 6:159,778,498...159,789,703 		JBrowse link
G TFRC transferrin receptor increases expression ISO Quartz results in increased expression of TFRC mRNA CTD PMID:19836432 NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153 		JBrowse link
G TGFB1 transforming growth factor beta 1 increases secretion EXP Quartz results in increased secretion of TGFB1 protein CTD PMID:35499148 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 increases expression ISO Quartz results in increased expression of TGFBR1 mRNA CTD PMID:19836432 NCBI chr 9:99,103,647...99,154,192
Ensembl chr 9:99,104,038...99,154,192 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 increases expression ISO Quartz results in increased expression of TIAM1 mRNA CTD PMID:19836432 NCBI chr21:31,118,418...31,559,087
Ensembl chr21:31,118,416...31,559,977 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP [Ascorbic Acid co-treated with Quartz] results in increased expression of TIMP1 mRNA CTD PMID:27381660 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TMEM45B transmembrane protein 45B increases expression
multiple interactions		 ISO Quartz results in increased expression of TMEM45B mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of TMEM45B mRNA]		 CTD PMID:32976597 NCBI chr11:129,815,848...129,860,003
Ensembl chr11:129,815,848...129,860,003 		JBrowse link
G TMEM72 transmembrane protein 72 multiple interactions
increases expression		 ISO Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of TMEM72 mRNA] CTD PMID:32976597 NCBI chr10:44,911,337...44,937,010
Ensembl chr10:44,911,316...44,937,010 		JBrowse link
G TNF tumor necrosis factor multiple interactions
increases expression
increases activity
increases secretion		 ISO
EXP		 Ascorbic Acid promotes the reaction [Quartz results in increased expression of TNF mRNA]; Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]; Butylated Hydroxytoluene inhibits the reaction [Dextran Sulfate promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]]; Butylated Hydroxytoluene inhibits the reaction [Dextran Sulfate promotes the reaction [Quartz results in increased secretion of TNF protein]]; CAT protein inhibits the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; CAT protein inhibits the reaction [Quartz results in increased secretion of TNF protein]; Dextran Sulfate promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; Dextran Sulfate promotes the reaction [Quartz results in increased secretion of TNF protein]; IFNG protein promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; IFNG protein promotes the reaction [Quartz results in increased secretion of TNF protein]; Mannitol inhibits the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; Mannitol inhibits the reaction [Quartz results in increased secretion of TNF protein]
aluminum lactate inhibits the reaction [Quartz results in increased expression of TNF mRNA]
Quartz results in increased activity of TNF protein
ATF3 protein affects the reaction [Quartz results in increased secretion of TNF protein]; Quartz results in increased expression of and results in increased secretion of TNF protein		 CTD PMID:11306444 PMID:18803060 PMID:19298665 PMID:19697923 PMID:19836432 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFSF10 TNF superfamily member 10 decreases expression EXP Quartz results in decreased expression of TNFSF10 mRNA CTD PMID:27917503 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475 		JBrowse link
G TP53 tumor protein p53 increases expression
increases mutagenesis
decreases expression
multiple interactions		 ISO
EXP		 Quartz results in increased expression of TRP53 protein
Quartz results in increased mutagenesis of TRP53 protein
Quartz results in decreased expression of TP53 mRNA; Quartz results in decreased expression of TP53 protein
FOSL1 promotes the reaction [Quartz results in decreased expression of TP53 protein]; MIR34C inhibits the reaction [Quartz results in decreased expression of TP53 protein]		 CTD PMID:11306444 PMID:27917503 PMID:35499148 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TPI1 triosephosphate isomerase 1 decreases expression EXP Quartz results in decreased expression of TPI1 protein CTD PMID:27917503 NCBI chr12:6,867,420...6,870,948
Ensembl chr12:6,867,119...6,870,948 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 increases expression ISO Quartz results in increased expression of TREM2 mRNA CTD PMID:19836432 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
G TUBA1C tubulin alpha 1c affects expression EXP Quartz affects the expression of TUBA1C protein CTD PMID:27917503 NCBI chr12:49,227,926...49,274,600
Ensembl chr12:49,188,736...49,274,600 		JBrowse link
G TWIST1 twist family bHLH transcription factor 1 increases expression
multiple interactions		 ISO Quartz results in increased expression of TWIST1 protein
Nicotine promotes the reaction [Quartz results in increased expression of TWIST1 protein]; staurosporine aglycone inhibits the reaction [[Nicotine co-treated with Quartz] results in increased expression of TWIST1 protein]		 CTD PMID:36868510 NCBI chr 7:19,113,047...19,117,636
Ensembl chr 7:19,020,991...19,117,636 		JBrowse link
G VCP valosin containing protein affects expression EXP Quartz affects the expression of VCP protein CTD PMID:27917503 NCBI chr 9:35,056,064...35,072,625
Ensembl chr 9:35,053,928...35,072,668 		JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions
increases secretion		 EXP
ISO		 [Ascorbic Acid co-treated with Quartz] results in increased expression of VEGFA mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased secretion of VEGFA protein]		 CTD PMID:27381660 PMID:32976597 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VIM vimentin multiple interactions
increases expression		 EXP
ISO		 [MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in increased expression of VIM protein]; FOSL1 promotes the reaction [Quartz results in increased expression of VIM protein]; MIR34C inhibits the reaction [Quartz results in increased expression of VIM protein]
Nicotine promotes the reaction [Quartz results in increased expression of VIM protein]; staurosporine aglycone inhibits the reaction [[Nicotine co-treated with Quartz] results in increased expression of VIM protein]		 CTD PMID:35499148 PMID:36868510 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G YAP1 Yes1 associated transcriptional regulator multiple interactions
affects localization
affects expression		 ISO CAV1 protein modified form inhibits the reaction [Quartz affects the localization of YAP1 protein]; CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of YAP1 protein]
Quartz affects the expression of YAP1 protein		 CTD PMID:36053221 NCBI chr11:102,110,447...102,233,424
Ensembl chr11:102,110,447...102,233,424 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon affects expression EXP Quartz affects the expression of YWHAE protein CTD PMID:27917503 NCBI chr17:1,344,275...1,400,222
Ensembl chr17:1,344,275...1,400,222 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26089
    chemical entity 26068
      chemical substance 15512
        mineral 4500
          oxide mineral 198
            quartz 198
Path 2
Term Annotations click to browse term
  CHEBI ontology 26089
    subatomic particle 26064
      composite particle 26064
        hadron 26064
          baryon 26064
            nucleon 26016
              atomic nucleus 26064
                atom 26064
                  main group element atom 25891
                    p-block element atom 25891
                      p-block molecular entity 25886
                        chalcogen molecular entity 24962
                          oxygen molecular entity 24852
                            oxide 13797
                              inorganic oxide 8408
                                silicon oxide 6046
                                  silicon dioxide 6046
                                    quartz 198
paths to the root