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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tetracycline
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Accession:CHEBI:27902 term browser browse the term
Definition:A broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria.
Synonyms:exact_synonym: (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
 related_synonym: (4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide;   Abramycin;   Achromycin;   Anhydrotetracycline;   Deschlorobiomycin;   Formula=C22H24N2O8;   InChI=1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1;   InChIKey=OFVLGDICTFRJMM-WESIUVDSSA-N;   Liquamycin;   SMILES=[H][C@@]12C[C@@]3([H])C(C(=O)c4c(O)cccc4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C;   Tetracyclin;   Tetrazyklin;   Tsiklomitsin;   tetracyclinum
 alt_id: CHEBI:26894;   CHEBI:45729;   CHEBI:9474
 xref: Beilstein:2230417;   CAS:60-54-8;   DrugBank:DB00759;   Drug_Central:2611;   Gmelin:1103368;   KEGG:C06570;   KEGG:D00201
 xref_mesh: MESH:D013752
 xref: MetaCyc:CPD0-1414;   PDBeChem:TAC;   PMID:11061623;   PMID:11550419;   PMID:11744940;   PMID:12934399;   PMID:14585720;   PMID:15825421;   PMID:15913752;   PMID:16443056;   PMID:1650428;   PMID:16749547;   PMID:17251127;   PMID:17260506;   PMID:18326855;   PMID:18406588;   PMID:19032078;   PMID:19112759;   PMID:19136803;   PMID:25286144;   PMID:26876942;   Patent:US2699054;   Patent:US2712517;   Patent:US2886595;   Patent:US3005023;   Patent:US3019173;   Patent:US3301899;   Reaxys:2230417;   VSDB:1739;   Wikipedia:Tetracycline
 cyclic_relationship: is_conjugate_acid_of CHEBI:71392;   is_conjugate_acid_of CHEBI:77932


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tetracycline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AADAC arylacetamide deacetylase decreases expression ISO Tetracycline results in decreased expression of AADAC mRNA CTD PMID:24489787 NCBI chr 3:151,814,116...151,828,488
Ensembl chr 3:151,814,073...151,828,488 		JBrowse link
G ABCA1 ATP binding cassette subfamily A member 1 increases expression ISO Tetracycline results in increased expression of ABCA1 mRNA CTD PMID:16917069 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ABCA8 ATP binding cassette subfamily A member 8 increases expression ISO Tetracycline results in increased expression of ABCA8B mRNA CTD PMID:16917069 NCBI chr17:68,867,289...68,955,392
Ensembl chr17:68,867,289...68,955,392 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 increases expression ISO Tetracycline results in increased expression of ABCB1 mRNA CTD PMID:17522070 PMID:19224547 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 decreases expression ISO Tetracycline results in decreased expression of ABCB11 mRNA CTD PMID:17522070 PMID:19224547 PMID:27765674 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ABCB4 ATP binding cassette subfamily B member 4 decreases expression ISO Tetracycline results in decreased expression of ABCB4 mRNA CTD PMID:24489787 PMID:27765674 NCBI chr 7:87,365,896...87,476,027
Ensembl chr 7:87,401,696...87,480,435 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 decreases expression ISO Tetracycline results in decreased expression of ABCC2 mRNA CTD PMID:27765674 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 increases expression ISO Tetracycline results in increased expression of ABCC3 mRNA CTD PMID:17522070 PMID:27765674 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) increases transport
increases expression		 EXP
ISO		 ABCC4 protein results in increased transport of Tetracycline
Tetracycline results in increased expression of ABCC4 mRNA		 CTD PMID:17939016 PMID:27765674 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475 		JBrowse link
G ABCD2 ATP binding cassette subfamily D member 2 decreases expression ISO Tetracycline results in decreased expression of ABCD2 mRNA CTD PMID:24489787 NCBI chr12:39,531,025...39,619,803
Ensembl chr12:39,550,033...39,619,803 		JBrowse link
G ABCD3 ATP binding cassette subfamily D member 3 increases expression
decreases expression		 ISO Tetracycline results in increased expression of ABCD3 mRNA
Tetracycline results in decreased expression of ABCD3 mRNA		 CTD PMID:16917069 PMID:24489787 NCBI chr 1:94,385,131...94,518,663
Ensembl chr 1:94,418,389...94,518,666 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) decreases expression ISO Tetracycline results in decreased expression of ABCG2 mRNA CTD PMID:24489787 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G ABCG5 ATP binding cassette subfamily G member 5 decreases expression ISO Tetracycline results in decreased expression of ABCG5 mRNA CTD PMID:24489787 PMID:27765674 NCBI chr 2:43,806,211...43,839,231
Ensembl chr 2:43,812,472...43,838,865 		JBrowse link
G ABCG8 ATP binding cassette subfamily G member 8 decreases expression ISO Tetracycline results in decreased expression of ABCG8 mRNA CTD PMID:24489787 NCBI chr 2:43,838,971...43,882,988
Ensembl chr 2:43,831,942...43,882,988 		JBrowse link
G ACACA acetyl-CoA carboxylase alpha decreases expression ISO Tetracycline results in decreased expression of ACACA mRNA CTD PMID:24489787 NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836 		JBrowse link
G ACADL acyl-CoA dehydrogenase long chain multiple interactions
decreases expression		 ISO bicyclol inhibits the reaction [Tetracycline results in decreased expression of ACADL mRNA] CTD PMID:19427351 NCBI chr 2:210,187,923...210,225,447
Ensembl chr 2:210,187,126...210,225,447 		JBrowse link
G ACADM acyl-CoA dehydrogenase medium chain decreases expression ISO Tetracycline results in decreased expression of ACADM mRNA CTD PMID:17522070 NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575 		JBrowse link
G ACADSB acyl-CoA dehydrogenase short/branched chain increases expression ISO Tetracycline results in increased expression of ACADSB mRNA CTD PMID:16917069 NCBI chr10:123,009,006...123,058,290
Ensembl chr10:123,008,979...123,058,290 		JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain decreases expression ISO Tetracycline results in decreased expression of ACADVL mRNA CTD PMID:24489787 NCBI chr17:7,217,125...7,225,266
Ensembl chr17:7,217,125...7,225,266 		JBrowse link
G ACAT1 acetyl-CoA acetyltransferase 1 decreases expression ISO Tetracycline results in decreased expression of ACAT1 mRNA CTD PMID:24489787 NCBI chr11:108,116,705...108,147,603
Ensembl chr11:108,116,695...108,147,603 		JBrowse link
G ACAT2 acetyl-CoA acetyltransferase 2 increases expression
decreases expression		 ISO Tetracycline results in increased expression of ACAT2 mRNA
Tetracycline results in decreased expression of ACAT2 mRNA		 CTD PMID:16917069 PMID:24489787 NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112 		JBrowse link
G ACBD5 acyl-CoA binding domain containing 5 increases expression ISO Tetracycline results in increased expression of ACBD5 mRNA CTD PMID:16917069 NCBI chr10:27,182,838...27,242,111
Ensembl chr10:27,168,135...27,243,046 		JBrowse link
G ACE2 angiotensin converting enzyme 2 increases expression EXP Tetracycline results in increased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G ACLY ATP citrate lyase decreases expression ISO Tetracycline results in decreased expression of ACLY mRNA CTD PMID:17522070 NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542 		JBrowse link
G ACOX1 acyl-CoA oxidase 1 increases expression
decreases expression		 ISO Tetracycline results in increased expression of ACOX1 mRNA
Tetracycline results in decreased expression of ACOX1 mRNA		 CTD PMID:16917069 PMID:24489787 NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177 		JBrowse link
G ACOX2 acyl-CoA oxidase 2 decreases expression ISO Tetracycline results in decreased expression of ACOX2 mRNA CTD PMID:19224547 PMID:24489787 NCBI chr 3:58,505,136...58,537,190
Ensembl chr 3:58,505,136...58,537,283 		JBrowse link
G ACSL1 acyl-CoA synthetase long chain family member 1 increases expression
decreases expression		 ISO Tetracycline results in increased expression of ACSL1 mRNA
Tetracycline results in decreased expression of ACSL1 mRNA		 CTD PMID:16917069 PMID:17522070 PMID:24489787 NCBI chr 4:184,755,595...184,826,594
Ensembl chr 4:184,755,595...184,826,818 		JBrowse link
G ACSM1 acyl-CoA synthetase medium chain family member 1 decreases expression ISO Tetracycline results in decreased expression of ACSM1 mRNA CTD PMID:24489787 NCBI chr16:20,623,235...20,697,680
Ensembl chr16:20,623,235...20,698,890 		JBrowse link
G ACSM2A acyl-CoA synthetase medium chain family member 2A increases expression ISO Tetracycline results in increased expression of ACSM2 mRNA CTD PMID:16917069 NCBI chr16:20,451,521...20,487,669
Ensembl chr16:20,451,461...20,487,669 		JBrowse link
G ACSM3 acyl-CoA synthetase medium chain family member 3 decreases expression ISO Tetracycline results in decreased expression of ACSM3 mRNA CTD PMID:24489787 NCBI chr16:20,674,405...20,797,581
Ensembl chr16:20,610,243...20,797,581 		JBrowse link
G ACSS2 acyl-CoA synthetase short chain family member 2 decreases expression ISO Tetracycline results in decreased expression of ACSS2 mRNA CTD PMID:24489787 NCBI chr20:34,874,989...34,927,959
Ensembl chr20:34,872,146...34,927,962 		JBrowse link
G ADIPOR2 adiponectin receptor 2 increases expression ISO Tetracycline results in increased expression of ADIPOR2 mRNA CTD PMID:16917069 NCBI chr12:1,691,070...1,788,674
Ensembl chr12:1,688,574...1,788,674 		JBrowse link
G AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 increases expression ISO Tetracycline results in increased expression of AGPAT2 mRNA CTD PMID:16917069 NCBI chr 9:136,673,143...136,687,457
Ensembl chr 9:136,673,143...136,687,457 		JBrowse link
G AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 decreases expression ISO Tetracycline results in decreased expression of AGPAT4 mRNA CTD PMID:16917069 NCBI chr 6:161,129,967...161,274,061
Ensembl chr 6:161,129,967...161,274,061 		JBrowse link
G AGT angiotensinogen decreases expression ISO Tetracycline results in decreased expression of AGT mRNA CTD PMID:24489787 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AK3 adenylate kinase 3 decreases expression ISO Tetracycline results in decreased expression of AK3 mRNA CTD PMID:24489787 NCBI chr 9:4,709,556...4,742,043
Ensembl chr 9:4,709,556...4,742,043 		JBrowse link
G AK4 adenylate kinase 4 increases expression ISO Tetracycline results in increased expression of AK4 protein CTD PMID:16538043 NCBI chr 1:65,147,552...65,232,145
Ensembl chr 1:65,147,549...65,232,145 		JBrowse link
G AKR1D1 aldo-keto reductase family 1 member D1 increases expression ISO Tetracycline results in increased expression of AKR1D1 mRNA CTD PMID:16917069 NCBI chr 7:138,076,459...138,118,305
Ensembl chr 7:138,002,324...138,118,305 		JBrowse link
G ALAS1 5'-aminolevulinate synthase 1 decreases expression ISO Tetracycline results in decreased expression of ALAS1 mRNA CTD PMID:24489787 NCBI chr 3:52,198,083...52,214,327
Ensembl chr 3:52,198,086...52,214,327 		JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 decreases expression ISO Tetracycline results in decreased expression of ALDH1A1 mRNA CTD PMID:24489787 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442 		JBrowse link
G ALDH3A2 aldehyde dehydrogenase 3 family member A2 decreases expression ISO Tetracycline results in decreased expression of ALDH3A2 mRNA CTD PMID:17522070 NCBI chr17:19,648,136...19,677,596
Ensembl chr17:19,648,136...19,685,760 		JBrowse link
G ALDOA aldolase, fructose-bisphosphate A increases expression ISO Tetracycline results in increased expression of ALDOA mRNA CTD PMID:17522070 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457 		JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein decreases expression ISO Tetracycline results in decreased expression of ALOX5AP mRNA CTD PMID:16917069 NCBI chr13:30,713,485...30,764,426
Ensembl chr13:30,713,478...30,764,426 		JBrowse link
G AMACR alpha-methylacyl-CoA racemase decreases expression ISO Tetracycline results in decreased expression of AMACR mRNA CTD PMID:24489787 NCBI chr 5:33,986,165...34,008,050
Ensembl chr 5:33,986,165...34,008,104 		JBrowse link
G ANGPTL3 angiopoietin like 3 decreases expression ISO Tetracycline results in decreased expression of ANGPTL3 mRNA CTD PMID:24489787 NCBI chr 1:62,597,520...62,606,313
Ensembl chr 1:62,597,520...62,606,313 		JBrowse link
G AOAH acyloxyacyl hydrolase increases expression ISO Tetracycline results in increased expression of AOAH mRNA CTD PMID:16917069 NCBI chr 7:36,512,941...36,724,494
Ensembl chr 7:36,512,941...36,724,549 		JBrowse link
G AP1S1 adaptor related protein complex 1 subunit sigma 1 decreases expression EXP Tetracycline results in decreased expression of AP1S1 mRNA CTD PMID:17175557 NCBI chr 7:101,154,476...101,161,276
Ensembl chr 7:101,154,456...101,161,596 		JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression ISO Tetracycline results in increased expression of APEX1 mRNA CTD PMID:17522070 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772 		JBrowse link
G APOB apolipoprotein B decreases expression ISO Tetracycline results in decreased expression of APOB mRNA CTD PMID:19224547 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G APOC1 apolipoprotein C1 decreases expression ISO Tetracycline results in decreased expression of APOC1 mRNA CTD PMID:16917069 NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349 		JBrowse link
G APOC2 apolipoprotein C2 decreases expression ISO Tetracycline results in decreased expression of APOC2 mRNA CTD PMID:16917069 PMID:24489787 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565 		JBrowse link
G APOC3 apolipoprotein C3 decreases expression ISO Tetracycline results in decreased expression of APOC3 mRNA CTD PMID:16917069 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072 		JBrowse link
G APOF apolipoprotein F decreases expression ISO Tetracycline results in decreased expression of APOF mRNA CTD PMID:24489787 NCBI chr12:56,360,568...56,362,857
Ensembl chr12:56,360,568...56,362,857 		JBrowse link
G AR androgen receptor decreases expression ISO Tetracycline results in decreased expression of AR mRNA CTD PMID:16917069 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator increases expression ISO Tetracycline results in increased expression of ARNT mRNA CTD PMID:16917069 NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708 		JBrowse link
G ARSA arylsulfatase A decreases expression ISO Tetracycline results in decreased expression of ARSA mRNA CTD PMID:16917069 NCBI chr22:50,622,754...50,628,152
Ensembl chr22:50,622,754...50,628,173 		JBrowse link
G ASGR2 asialoglycoprotein receptor 2 decreases expression ISO Tetracycline results in decreased expression of ASGR2 mRNA CTD PMID:24489787 NCBI chr17:7,101,322...7,115,146
Ensembl chr17:7,101,322...7,115,700 		JBrowse link
G ASL argininosuccinate lyase increases expression ISO Tetracycline results in increased expression of ASL mRNA CTD PMID:17522070 NCBI chr 7:66,075,819...66,093,576
Ensembl chr 7:66,075,800...66,094,697 		JBrowse link
G ASNS asparagine synthetase (glutamine-hydrolyzing) increases expression EXP Tetracycline results in increased expression of ASNS mRNA CTD PMID:17175557 NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542 		JBrowse link
G ATP11A ATPase phospholipid transporting 11A decreases expression ISO Tetracycline results in decreased expression of ATP11A mRNA CTD PMID:16917069 NCBI chr13:112,690,038...112,887,168
Ensembl chr13:112,690,038...112,887,168 		JBrowse link
G AUH AU RNA binding methylglutaconyl-CoA hydratase increases expression ISO Tetracycline results in increased expression of AUH mRNA CTD PMID:16917069 NCBI chr 9:91,213,823...91,361,918
Ensembl chr 9:91,213,815...91,361,918 		JBrowse link
G BBOX1 gamma-butyrobetaine hydroxylase 1 decreases expression ISO Tetracycline results in decreased expression of BBOX1 mRNA CTD PMID:24489787 NCBI chr11:27,040,815...27,127,809
Ensembl chr11:27,040,725...27,127,809 		JBrowse link
G BCKDHA branched chain keto acid dehydrogenase E1 subunit alpha increases expression ISO Tetracycline results in increased expression of BCKDHA protein CTD PMID:16538043 NCBI chr19:41,397,818...41,425,002
Ensembl chr19:41,397,808...41,425,002 		JBrowse link
G BDH1 3-hydroxybutyrate dehydrogenase 1 decreases expression ISO Tetracycline results in decreased expression of BDH1 mRNA CTD PMID:24489787 NCBI chr 3:197,509,783...197,573,343
Ensembl chr 3:197,509,783...197,573,323 		JBrowse link
G BSCL2 BSCL2 lipid droplet biogenesis associated, seipin decreases expression ISO Tetracycline results in decreased expression of BSCL2 mRNA CTD PMID:24489787 NCBI chr11:62,690,262...62,709,537
Ensembl chr11:62,689,289...62,709,845 		JBrowse link
G BTG2 BTG anti-proliferation factor 2 increases expression ISO Tetracycline results in increased expression of BTG2 mRNA CTD PMID:17522070 NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602 		JBrowse link
G CA3 carbonic anhydrase 3 increases expression ISO Tetracycline results in increased expression of CAR3 protein CTD PMID:16538043 NCBI chr 8:85,438,859...85,449,040
Ensembl chr 8:85,373,436...85,449,040 		JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 increases expression ISO Tetracycline results in increased expression of CACNA2D1 mRNA CTD PMID:16917069 NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,956 		JBrowse link
G CALU calumenin increases expression ISO Tetracycline results in increased expression of CALU mRNA CTD PMID:17522070 NCBI chr 7:128,739,359...128,773,400
Ensembl chr 7:128,739,292...128,773,400 		JBrowse link
G CASP3 caspase 3 decreases expression ISO Tetracycline results in decreased expression of CASP3 mRNA CTD PMID:24489787 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAT catalase increases expression
decreases expression		 ISO Tetracycline results in increased expression of CAT mRNA
Tetracycline results in decreased expression of CAT mRNA		 CTD PMID:16917069 PMID:17522070 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CBFA2T2 CBFA2/RUNX1 partner transcriptional co-repressor 2 increases expression ISO Tetracycline results in increased expression of CBFA2T2 mRNA CTD PMID:16917069 NCBI chr20:33,490,096...33,650,030
Ensembl chr20:33,490,075...33,650,036 		JBrowse link
G CBS cystathionine beta-synthase decreases expression ISO Tetracycline results in decreased expression of CBS mRNA CTD PMID:24489787 NCBI chr21:43,053,191...43,076,873
Ensembl chr21:43,053,191...43,076,943 		JBrowse link
G CCN2 cellular communication network factor 2 increases expression ISO Tetracycline results in increased expression of CCN2 mRNA CTD PMID:16917069 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CCNB3 cyclin B3 increases expression ISO Tetracycline results in increased expression of CCNB3 mRNA CTD PMID:16917069 NCBI chr  X:50,202,713...50,351,914
Ensembl chr  X:50,202,713...50,351,914 		JBrowse link
G CCND1 cyclin D1 decreases expression ISO Tetracycline results in decreased expression of CCND1 mRNA CTD PMID:19224547 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCNG1 cyclin G1 increases expression ISO Tetracycline results in increased expression of CCNG1 mRNA CTD PMID:17522070 NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,446,151 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) multiple interactions
increases expression		 EXP
ISO		 [Tetracycline results in increased expression of CD36 protein] which results in increased uptake of Fatty Acids
Tetracycline results in increased expression of CD36 mRNA; Tetracycline results in increased expression of CD36 protein		 CTD PMID:25745068 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CERS2 ceramide synthase 2 increases expression ISO Tetracycline results in increased expression of CERS2 mRNA CTD PMID:16917069 NCBI chr 1:150,965,186...150,974,835
Ensembl chr 1:150,960,583...150,975,003 		JBrowse link
G CERS5 ceramide synthase 5 increases expression ISO Tetracycline results in increased expression of CERS5 mRNA CTD PMID:16917069 NCBI chr12:50,129,289...50,167,369
Ensembl chr12:50,129,289...50,167,533 		JBrowse link
G CHKA choline kinase alpha increases expression ISO Tetracycline results in increased expression of CHKA mRNA CTD PMID:16917069 NCBI chr11:68,052,859...68,121,388
Ensembl chr11:68,052,859...68,121,444 		JBrowse link
G CIDEB cell death inducing DFFA like effector b decreases expression ISO Tetracycline results in decreased expression of CIDEB mRNA CTD PMID:24489787 NCBI chr14:24,305,187...24,311,435
Ensembl chr14:24,305,187...24,311,430 		JBrowse link
G CLDN10 claudin 10 decreases expression EXP Tetracycline results in decreased expression of CLDN10 mRNA CTD PMID:28882639 NCBI chr13:95,433,755...95,579,759
Ensembl chr13:95,433,604...95,579,759 		JBrowse link
G CLDN11 claudin 11 decreases expression EXP Tetracycline results in decreased expression of CLDN11 mRNA CTD PMID:28882639 NCBI chr 3:170,418,868...170,434,691
Ensembl chr 3:170,418,868...170,454,733 		JBrowse link
G CLDN15 claudin 15 decreases expression EXP Tetracycline results in decreased expression of CLDN15 mRNA CTD PMID:28882639 NCBI chr 7:101,232,094...101,238,820
Ensembl chr 7:101,232,092...101,238,820 		JBrowse link
G CLDN2 claudin 2 decreases expression EXP Tetracycline results in decreased expression of CLDN2 mRNA CTD PMID:28882639 NCBI chr  X:106,900,164...106,930,861
Ensembl chr  X:106,900,164...106,930,861 		JBrowse link
G CLDN6 claudin 6 decreases expression EXP Tetracycline results in decreased expression of CLDN6 mRNA CTD PMID:28882639 NCBI chr16:3,014,712...3,018,183
Ensembl chr16:3,014,712...3,020,071 		JBrowse link
G CLDN8 claudin 8 decreases expression EXP Tetracycline results in decreased expression of CLDN8 mRNA CTD PMID:28882639 NCBI chr21:30,214,006...30,216,097
Ensembl chr21:30,214,006...30,216,097 		JBrowse link
G CLU clusterin increases expression ISO Tetracycline results in increased expression of CLU mRNA CTD PMID:17522070 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G COX19 cytochrome c oxidase assembly factor COX19 decreases expression ISO Tetracycline results in decreased expression of COX19 mRNA CTD PMID:24489787 NCBI chr 7:964,852...975,549
Ensembl chr 7:898,778...975,549 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A decreases expression ISO Tetracycline results in decreased expression of CPT1A mRNA CTD PMID:19224547 PMID:24489787 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410 		JBrowse link
G CRAT carnitine O-acetyltransferase decreases expression ISO Tetracycline results in decreased expression of CRAT mRNA CTD PMID:16917069 NCBI chr 9:129,094,794...129,110,793
Ensembl chr 9:129,094,142...129,111,189 		JBrowse link
G CROT carnitine O-octanoyltransferase increases expression
decreases expression		 ISO Tetracycline results in increased expression of CROT mRNA
Tetracycline results in decreased expression of CROT mRNA		 CTD PMID:16917069 PMID:24489787 NCBI chr 7:87,345,664...87,399,794
Ensembl chr 7:87,345,664...87,399,794 		JBrowse link
G CRYAB crystallin alpha B decreases expression ISO Tetracycline results in decreased expression of CRYAB mRNA CTD PMID:24489787 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722 		JBrowse link
G CSF1 colony stimulating factor 1 increases expression ISO Tetracycline results in increased expression of CSF1 mRNA CTD PMID:16917069 NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992 		JBrowse link
G CTSL cathepsin L increases expression ISO Tetracycline results in increased expression of CTSL mRNA CTD PMID:17522070 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 decreases expression ISO Tetracycline results in decreased expression of CXCL12 mRNA CTD PMID:24489787 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CYB5A cytochrome b5 type A decreases expression ISO Tetracycline results in decreased expression of CYB5A mRNA CTD PMID:16917069 NCBI chr18:74,250,846...74,291,963
Ensembl chr18:74,250,846...74,291,973 		JBrowse link
G CYB5B cytochrome b5 type B increases expression ISO Tetracycline results in increased expression of CYB5B mRNA CTD PMID:16917069 NCBI chr16:69,424,619...69,466,264
Ensembl chr16:69,398,402...69,466,264 		JBrowse link
G CYB5R3 cytochrome b5 reductase 3 decreases expression ISO Tetracycline results in decreased expression of CYB5R3 mRNA CTD PMID:17522070 NCBI chr22:42,617,840...42,649,392
Ensembl chr22:42,615,730...42,720,870 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 decreases expression ISO Tetracycline results in decreased expression of CYP17A1 mRNA CTD PMID:16917069 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases expression ISO Tetracycline results in decreased expression of CYP1A1 mRNA CTD PMID:19224547 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP21A2 cytochrome P450 family 21 subfamily A member 2 increases expression ISO Tetracycline results in increased expression of CYP21A1 mRNA CTD PMID:16917069 NCBI chr 6:32,038,415...32,041,644
Ensembl chr 6:32,038,327...32,041,644 		JBrowse link
G CYP26A1 cytochrome P450 family 26 subfamily A member 1 decreases expression ISO Tetracycline results in decreased expression of CYP26A1 mRNA CTD PMID:16917069 NCBI chr10:93,073,475...93,077,885
Ensembl chr10:93,073,475...93,077,885 		JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 decreases expression ISO Tetracycline results in decreased expression of CYP27A1 mRNA CTD PMID:24489787 NCBI chr 2:218,782,147...218,815,293
Ensembl chr 2:218,781,749...218,815,293 		JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 decreases expression ISO Tetracycline results in decreased expression of CYP2A5 mRNA CTD PMID:16917069 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447 		JBrowse link
G CYP2A7 cytochrome P450 family 2 subfamily A member 7 decreases expression ISO Tetracycline results in decreased expression of CYP2A4 mRNA CTD PMID:16917069 NCBI chr19:40,875,439...40,882,231
Ensembl chr19:40,875,439...40,882,752 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 increases expression ISO Tetracycline results in increased expression of CYP2C38 mRNA CTD PMID:16917069 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions
decreases expression		 ISO bicyclol inhibits the reaction [Tetracycline results in decreased expression of CYP2E1 mRNA] CTD PMID:19427351 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 increases expression ISO Tetracycline results in increased expression of CYP2J9 mRNA CTD PMID:16917069 NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 multiple interactions
decreases expression
increases expression		 EXP
ISO		 Tetracycline results in increased expression of and results in increased activity of CYP3A4 protein
Tetracycline results in decreased expression of CYP3A4 mRNA
Tetracycline results in increased expression of CYP3A4 mRNA		 CTD PMID:18505790 PMID:19224547 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP46A1 cytochrome P450 family 46 subfamily A member 1 decreases expression ISO Tetracycline results in decreased expression of CYP46A1 mRNA CTD PMID:16917069 NCBI chr14:99,684,298...99,727,301
Ensembl chr14:99,684,298...99,727,301 		JBrowse link
G CYP4A22 cytochrome P450 family 4 subfamily A member 22 increases expression
decreases expression		 ISO Tetracycline results in increased expression of CYP4A1 mRNA
Tetracycline results in decreased expression of CYP4A22 mRNA		 CTD PMID:12883083 PMID:19224547 NCBI chr 1:47,137,441...47,149,727
Ensembl chr 1:47,137,435...47,149,727 		JBrowse link
G CYP4F12 cytochrome P450 family 4 subfamily F member 12 increases expression ISO Tetracycline results in increased expression of CYP4F14 mRNA CTD PMID:16917069 NCBI chr19:15,673,087...15,697,174
Ensembl chr19:15,673,018...15,697,174 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 increases expression ISO Tetracycline results in increased expression of CYP4F18 mRNA CTD PMID:16917069 NCBI chr19:15,640,897...15,662,825
Ensembl chr19:15,640,897...15,662,825 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 increases expression ISO Tetracycline results in increased expression of CYP51 mRNA CTD PMID:16917069 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 increases expression
decreases expression		 ISO Tetracycline results in increased expression of CYP7A1 mRNA
Tetracycline results in decreased expression of CYP7A1 mRNA		 CTD PMID:16917069 PMID:19224547 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163 		JBrowse link
G CYP7B1 cytochrome P450 family 7 subfamily B member 1 decreases expression ISO Tetracycline results in decreased expression of CYP7B1 mRNA CTD PMID:24489787 NCBI chr 8:64,586,575...64,798,737
Ensembl chr 8:64,587,763...64,798,737 		JBrowse link
G CYP8B1 cytochrome P450 family 8 subfamily B member 1 increases expression
decreases expression		 ISO Tetracycline results in increased expression of CYP8B1 mRNA
Tetracycline results in decreased expression of CYP8B1 mRNA		 CTD PMID:16917069 PMID:24489787 NCBI chr 3:42,872,192...42,875,879
Ensembl chr 3:42,856,005...42,875,898 		JBrowse link
G DBI diazepam binding inhibitor, acyl-CoA binding protein decreases expression ISO Tetracycline results in decreased expression of DBI mRNA CTD PMID:16917069 NCBI chr 2:119,366,977...119,372,543
Ensembl chr 2:119,366,924...119,372,550 		JBrowse link
G DDC dopa decarboxylase decreases expression ISO Tetracycline results in decreased expression of DDC mRNA CTD PMID:24489787 NCBI chr 7:50,458,442...50,565,405
Ensembl chr 7:50,458,436...50,565,405 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression ISO Tetracycline results in increased expression of DDIT3 mRNA CTD PMID:12883083 PMID:17522070 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DEPP1 DEPP autophagy regulator 1 increases expression EXP Tetracycline results in increased expression of DEPP1 mRNA CTD PMID:17175557 NCBI chr10:44,976,128...44,978,809
Ensembl chr10:44,970,981...44,978,809 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 increases expression
multiple interactions		 EXP
ISO		 Tetracycline results in increased expression of DGAT2 protein
Tetracycline results in increased expression of DGAT2 mRNA; Tetracycline results in increased expression of DGAT2 protein
Tetracycline promotes the reaction [DGAT2 protein results in increased chemical synthesis of Triglycerides]		 CTD PMID:25745068 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535 		JBrowse link
G DGKA diacylglycerol kinase alpha decreases expression ISO Tetracycline results in decreased expression of DGKA mRNA CTD PMID:16917069 NCBI chr12:55,927,316...55,954,023
Ensembl chr12:55,927,319...55,954,027 		JBrowse link
G DHX29 DExH-box helicase 29 increases expression ISO Tetracycline results in increased expression of DHX29 mRNA CTD PMID:16917069 NCBI chr 5:55,256,055...55,307,694
Ensembl chr 5:55,256,055...55,307,694 		JBrowse link
G DNAJB8 DnaJ heat shock protein family (Hsp40) member B8 increases expression ISO Tetracycline results in increased expression of DNAJB8 mRNA CTD PMID:16917069 NCBI chr 3:128,462,437...128,466,890
Ensembl chr 3:128,462,437...128,466,968 		JBrowse link
G DPM1 dolichyl-phosphate mannosyltransferase subunit 1, catalytic decreases expression ISO Tetracycline results in decreased expression of DPM1 mRNA CTD PMID:16917069 NCBI chr20:50,934,855...50,958,564
Ensembl chr20:50,934,867...50,959,140 		JBrowse link
G ECI1 enoyl-CoA delta isomerase 1 decreases expression ISO Tetracycline results in decreased expression of ECI1 mRNA CTD PMID:16917069 NCBI chr16:2,239,402...2,251,587
Ensembl chr16:2,239,402...2,252,300 		JBrowse link
G EGFR epidermal growth factor receptor decreases expression ISO Tetracycline results in decreased expression of EGFR mRNA CTD PMID:24489787 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EHHADH enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase decreases expression EXP Tetracycline results in decreased expression of EHHADH mRNA CTD PMID:27089845 NCBI chr 3:185,190,624...185,254,049
Ensembl chr 3:185,190,624...185,281,990 		JBrowse link
G ELOVL2 ELOVL fatty acid elongase 2 decreases expression ISO Tetracycline results in decreased expression of ELOVL2 mRNA CTD PMID:24489787 NCBI chr 6:10,980,759...11,044,305
Ensembl chr 6:10,980,759...11,044,305 		JBrowse link
G ELOVL3 ELOVL fatty acid elongase 3 increases expression ISO Tetracycline results in increased expression of ELOVL3 mRNA CTD PMID:16917069 NCBI chr10:102,224,767...102,229,589
Ensembl chr10:102,226,299...102,229,589 		JBrowse link
G ELOVL5 ELOVL fatty acid elongase 5 increases expression ISO Tetracycline results in increased expression of ELOVL5 mRNA CTD PMID:16917069 NCBI chr 6:53,267,404...53,348,950
Ensembl chr 6:53,267,398...53,349,179 		JBrowse link
G ELOVL6 ELOVL fatty acid elongase 6 increases expression
decreases expression		 ISO Tetracycline results in increased expression of ELOVL6 mRNA
Tetracycline results in decreased expression of ELOVL6 mRNA		 CTD PMID:16917069 PMID:19224547 NCBI chr 4:110,045,846...110,199,202
Ensembl chr 4:110,045,846...110,199,199 		JBrowse link
G ENDOG endonuclease G decreases expression ISO Tetracycline results in decreased expression of ENDOG mRNA CTD PMID:24489787 NCBI chr 9:128,818,500...128,822,676
Ensembl chr 9:128,818,500...128,822,676 		JBrowse link
G EPHX1 epoxide hydrolase 1 decreases expression ISO Tetracycline results in decreased expression of EPHX1 mRNA CTD PMID:24489787 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563 		JBrowse link
G EPHX2 epoxide hydrolase 2 decreases expression ISO Tetracycline results in decreased expression of EPHX2 mRNA CTD PMID:24489787 NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564 		JBrowse link
G ERGIC2 ERGIC and golgi 2 increases expression ISO Tetracycline results in increased expression of ERGIC2 mRNA CTD PMID:16917069 NCBI chr12:29,337,352...29,381,172
Ensembl chr12:29,337,352...29,381,189 		JBrowse link
G ETFDH electron transfer flavoprotein dehydrogenase decreases expression ISO Tetracycline results in decreased expression of ETFDH mRNA CTD PMID:24489787 NCBI chr 4:158,672,296...158,709,623
Ensembl chr 4:158,671,968...158,710,742 		JBrowse link
G EXOSC10 exosome component 10 increases expression ISO Tetracycline results in increased expression of EXOSC10 mRNA CTD PMID:16917069 NCBI chr 1:11,066,618...11,099,869
Ensembl chr 1:11,066,618...11,099,869 		JBrowse link
G EXOSC9 exosome component 9 increases expression ISO Tetracycline results in increased expression of EXOSC9 mRNA CTD PMID:16917069 NCBI chr 4:121,801,323...121,817,021
Ensembl chr 4:121,801,318...121,817,021 		JBrowse link
G F10 coagulation factor X decreases expression ISO Tetracycline results in decreased expression of F10 mRNA CTD PMID:24489787 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529 		JBrowse link
G FAAH fatty acid amide hydrolase increases expression ISO Tetracycline results in increased expression of FAAH mRNA CTD PMID:16917069 NCBI chr 1:46,394,317...46,413,845
Ensembl chr 1:46,394,317...46,413,848 		JBrowse link
G FABP1 fatty acid binding protein 1 decreases expression ISO Tetracycline results in decreased expression of FABP1 mRNA CTD PMID:16917069 PMID:17522070 PMID:19224547 PMID:24489787 NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062 		JBrowse link
G FABP4 fatty acid binding protein 4 decreases expression ISO Tetracycline results in decreased expression of FABP4 mRNA CTD PMID:16917069 NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236 		JBrowse link
G FABP7 fatty acid binding protein 7 decreases expression ISO Tetracycline results in decreased expression of FABP7 mRNA CTD PMID:16917069 NCBI chr 6:122,749,201...122,784,074
Ensembl chr 6:122,779,716...122,784,074 		JBrowse link
G FADS1 fatty acid desaturase 1 decreases expression ISO Tetracycline results in decreased expression of FADS1 mRNA CTD PMID:17522070 NCBI chr11:61,799,627...61,817,003
Ensembl chr11:61,799,627...61,829,318 		JBrowse link
G FAS Fas cell surface death receptor decreases expression ISO Tetracycline results in decreased expression of FAS mRNA CTD PMID:24489787 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASN fatty acid synthase decreases expression ISO Tetracycline results in decreased expression of FASN mRNA CTD PMID:17522070 PMID:19224547 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 decreases expression ISO Tetracycline results in decreased expression of FDFT1 mRNA CTD PMID:24489787 NCBI chr 8:11,795,582...11,839,309
Ensembl chr 8:11,795,573...11,839,395 		JBrowse link
G FDX1 ferredoxin 1 decreases expression ISO Tetracycline results in decreased expression of FDX1 mRNA CTD PMID:16917069 NCBI chr11:110,429,331...110,464,884
Ensembl chr11:110,429,948...110,464,884 		JBrowse link
G FEZF2 FEZ family zinc finger 2 increases expression ISO Tetracycline results in increased expression of FEZF2 mRNA CTD PMID:16917069 NCBI chr 3:62,369,681...62,373,550
Ensembl chr 3:62,369,681...62,374,324 		JBrowse link
G FGA fibrinogen alpha chain increases expression ISO Tetracycline results in increased expression of FGA mRNA CTD PMID:17522070 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742 		JBrowse link
G FGB fibrinogen beta chain increases expression ISO Tetracycline results in increased expression of FGB mRNA CTD PMID:17522070 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807 		JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 decreases expression ISO Tetracycline results in decreased expression of FMO1 mRNA CTD PMID:17522070 NCBI chr 1:171,248,494...171,285,978
Ensembl chr 1:171,248,471...171,285,978 		JBrowse link
G FNDC4 fibronectin type III domain containing 4 increases expression EXP Tetracycline results in increased expression of FNDC4 mRNA CTD PMID:17175557 NCBI chr 2:27,491,883...27,495,200
Ensembl chr 2:27,491,883...27,495,200 		JBrowse link
G FOXA1 forkhead box A1 decreases expression ISO Tetracycline results in decreased expression of FOXA1 mRNA CTD PMID:24469900 NCBI chr14:37,589,552...37,595,249
Ensembl chr14:37,589,552...37,596,059 		JBrowse link
G FXYD7 FXYD domain containing ion transport regulator 7 increases expression ISO Tetracycline results in increased expression of FXYD7 mRNA CTD PMID:16917069 NCBI chr19:35,143,255...35,154,302
Ensembl chr19:35,143,250...35,154,302 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO Tetracycline results in decreased expression of G6PC1 mRNA CTD PMID:24489787 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression ISO Tetracycline results in increased expression of GADD45A mRNA CTD PMID:17522070 PMID:19224547 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GATA2 GATA binding protein 2 increases expression ISO Tetracycline results in increased expression of GATA2 mRNA CTD PMID:16917069 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201 		JBrowse link
G GBA2 glucosylceramidase beta 2 increases expression ISO Tetracycline results in increased expression of GBA2 mRNA CTD PMID:16917069 NCBI chr 9:35,736,866...35,749,228
Ensembl chr 9:35,736,866...35,749,228 		JBrowse link
G GDE1 glycerophosphodiester phosphodiesterase 1 decreases expression ISO Tetracycline results in decreased expression of GDE1 mRNA CTD PMID:16917069 NCBI chr16:19,501,693...19,522,098
Ensembl chr16:19,501,693...19,522,123 		JBrowse link
G GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 decreases expression ISO Tetracycline results in decreased expression of GDPD1 mRNA CTD PMID:16917069 NCBI chr17:59,220,511...59,275,970
Ensembl chr17:59,220,467...59,275,970 		JBrowse link
G GGA1 golgi associated, gamma adaptin ear containing, ARF binding protein 1 increases expression ISO Tetracycline results in increased expression of GGA1 mRNA CTD PMID:16917069 NCBI chr22:37,608,834...37,633,564
Ensembl chr22:37,608,474...37,633,564 		JBrowse link
G GJA8 gap junction protein alpha 8 decreases expression EXP Tetracycline results in decreased expression of GJA8 mRNA CTD PMID:28882639 NCBI chr 1:147,902,795...147,914,486
Ensembl chr 1:147,902,795...147,909,269 		JBrowse link
G GJD2 gap junction protein delta 2 decreases expression EXP Tetracycline results in decreased expression of GJD2 mRNA CTD PMID:28882639 NCBI chr15:34,751,032...34,754,998
Ensembl chr15:34,751,032...34,754,998 		JBrowse link
G GLUD1 glutamate dehydrogenase 1 increases expression ISO Tetracycline results in increased expression of GLUD1 protein CTD PMID:16538043 NCBI chr10:87,050,202...87,094,843
Ensembl chr10:87,050,202...87,094,843 		JBrowse link
G GLYAT glycine-N-acyltransferase decreases expression ISO Tetracycline results in decreased expression of GLYAT mRNA CTD PMID:24489787 NCBI chr11:58,708,757...58,731,943
Ensembl chr11:58,640,426...58,731,974 		JBrowse link
G GMPR2 guanosine monophosphate reductase 2 increases expression ISO Tetracycline results in increased expression of GMPR2 mRNA CTD PMID:16917069 NCBI chr14:24,232,622...24,239,242
Ensembl chr14:24,232,422...24,239,242 		JBrowse link
G GPD1 glycerol-3-phosphate dehydrogenase 1 decreases expression ISO Tetracycline results in decreased expression of GPD1 mRNA CTD PMID:24489787 NCBI chr12:50,104,008...50,111,313
Ensembl chr12:50,103,982...50,111,313 		JBrowse link
G GPD2 glycerol-3-phosphate dehydrogenase 2 increases expression ISO Tetracycline results in increased expression of GPD2 mRNA CTD PMID:16917069 NCBI chr 2:156,400,281...156,586,403
Ensembl chr 2:156,435,290...156,613,735 		JBrowse link
G GPR151 G protein-coupled receptor 151 increases expression ISO Tetracycline results in increased expression of GPR151 mRNA CTD PMID:16917069 NCBI chr 5:146,513,144...146,516,190
Ensembl chr 5:146,513,144...146,516,190 		JBrowse link
G GPT2 glutamic--pyruvic transaminase 2 decreases expression ISO Tetracycline results in decreased expression of GPT2 mRNA CTD PMID:24489787 NCBI chr16:46,884,362...46,931,289
Ensembl chr16:46,884,362...46,931,289 		JBrowse link
G GPX1 glutathione peroxidase 1 decreases expression ISO Tetracycline results in decreased expression of GPX1 mRNA CTD PMID:17522070 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GPX3 glutathione peroxidase 3 decreases expression ISO Tetracycline results in decreased expression of GPX3 mRNA CTD PMID:16917069 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G GPX4 glutathione peroxidase 4 decreases expression ISO Tetracycline results in decreased expression of GPX4 mRNA CTD PMID:16917069 NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791 		JBrowse link
G GSTA2 glutathione S-transferase alpha 2 decreases expression ISO Tetracycline results in decreased expression of GSTA2 mRNA CTD PMID:19224547 NCBI chr 6:52,750,087...52,763,475
Ensembl chr 6:52,750,087...52,763,475 		JBrowse link
G GSTM3 glutathione S-transferase mu 3 decreases activity
decreases expression		 EXP
ISO		 Tetracycline results in decreased activity of GSTM3 protein
Tetracycline results in decreased expression of GSTM3 mRNA		 CTD PMID:11807801 PMID:17522070 NCBI chr 1:109,733,937...109,741,038
Ensembl chr 1:109,733,932...109,741,038 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 multiple interactions
decreases activity		 EXP Tetracycline inhibits the reaction [GSTP1 protein affects the metabolism of and results in decreased activity of Ethacrynic Acid]
Tetracycline results in decreased activity of GSTP1 protein		 CTD PMID:11807801 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G GYS2 glycogen synthase 2 decreases expression ISO Tetracycline results in decreased expression of GYS2 mRNA CTD PMID:19224547 NCBI chr12:21,532,577...21,604,847
Ensembl chr12:21,536,107...21,604,847 		JBrowse link
G H4C14 H4 clustered histone 14 increases expression ISO Tetracycline results in increased expression of H4C14 mRNA CTD PMID:16917069 NCBI chr 1:149,832,657...149,833,052
Ensembl chr 1:149,832,657...149,839,767 		JBrowse link
G HADH hydroxyacyl-CoA dehydrogenase decreases expression ISO Tetracycline results in decreased expression of HADH mRNA CTD PMID:24489787 NCBI chr 4:107,989,889...108,035,171
Ensembl chr 4:107,989,714...108,035,241 		JBrowse link
G HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha increases expression
decreases expression		 ISO Tetracycline results in increased expression of HADHA mRNA
Tetracycline results in decreased expression of HADHA mRNA		 CTD PMID:16917069 PMID:24489787 NCBI chr 2:26,190,635...26,244,632
Ensembl chr 2:26,190,635...26,244,672 		JBrowse link
G HEXB hexosaminidase subunit beta increases expression ISO Tetracycline results in increased expression of HEXB mRNA CTD PMID:16917069 NCBI chr 5:74,640,023...74,721,288
Ensembl chr 5:74,640,023...74,722,647 		JBrowse link
G HHEX hematopoietically expressed homeobox decreases expression ISO Tetracycline results in decreased expression of HHEX mRNA CTD PMID:24469900 NCBI chr10:92,689,955...92,695,647
Ensembl chr10:92,689,955...92,695,647 		JBrowse link
G HIBADH 3-hydroxyisobutyrate dehydrogenase decreases expression ISO Tetracycline results in decreased expression of HIBADH mRNA CTD PMID:17522070 NCBI chr 7:27,525,442...27,662,883
Ensembl chr 7:27,525,442...27,662,883 		JBrowse link
G HJV hemojuvelin BMP co-receptor decreases expression ISO Tetracycline results in decreased expression of HJV mRNA CTD PMID:24489787 NCBI chr 1:146,017,470...146,021,735
Ensembl chr 1:146,017,468...146,036,746 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO Tetracycline results in decreased expression of HMGCR mRNA CTD PMID:19224547 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Tetracycline results in increased expression of HMGCS1 mRNA CTD PMID:16917069 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression ISO Tetracycline results in decreased expression of HMGCS2 mRNA CTD PMID:24489787 NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905 		JBrowse link
G HMOX1 heme oxygenase 1 increases expression ISO Tetracycline results in increased expression of HMOX1 mRNA CTD PMID:19224547 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha decreases expression ISO Tetracycline results in decreased expression of HNF4A mRNA CTD PMID:24469900 PMID:24489787 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845 		JBrowse link
G HPGD 15-hydroxyprostaglandin dehydrogenase decreases expression ISO Tetracycline results in decreased expression of HPGD mRNA CTD PMID:24489787 NCBI chr 4:174,490,175...174,522,893
Ensembl chr 4:174,490,175...174,523,154 		JBrowse link
G HPN hepsin decreases expression ISO Tetracycline results in decreased expression of HPN mRNA CTD PMID:19224547 NCBI chr19:35,040,506...35,066,573
Ensembl chr19:35,040,506...35,066,573 		JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 increases expression ISO Tetracycline results in increased expression of HSD17B1 mRNA CTD PMID:16917069 NCBI chr17:42,552,923...42,555,214
Ensembl chr17:42,552,922...42,555,214 		JBrowse link
G HSD17B2 hydroxysteroid 17-beta dehydrogenase 2 increases expression ISO Tetracycline results in increased expression of HSD17B2 mRNA CTD PMID:16917069 NCBI chr16:82,035,253...82,098,534
Ensembl chr16:82,035,004...82,098,534 		JBrowse link
G HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 decreases expression ISO Tetracycline results in decreased expression of HSD17B4 mRNA CTD PMID:24489787 NCBI chr 5:119,452,497...119,542,332
Ensembl chr 5:119,452,465...119,637,199 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression ISO Tetracycline results in increased expression of HSD3B2 mRNA CTD PMID:16917069 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 increases expression ISO Tetracycline results in increased expression of HSD3B7 mRNA CTD PMID:16917069 NCBI chr16:30,985,207...30,989,147
Ensembl chr16:30,985,207...30,989,147 		JBrowse link
G HSF2 heat shock transcription factor 2 decreases expression ISO Tetracycline results in decreased expression of HSF2 mRNA CTD PMID:24489787 NCBI chr 6:122,399,551...122,433,119
Ensembl chr 6:122,399,551...122,433,119 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 increases expression ISO Tetracycline results in increased expression of HSP90B1 mRNA CTD PMID:16917069 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A increases expression ISO Tetracycline results in increased expression of HSPA1A mRNA CTD PMID:17522070 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 increases expression ISO Tetracycline results in increased expression of HSPD1 protein CTD PMID:16538043 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 increases expression ISO Tetracycline results in increased expression of ICAM1 mRNA CTD PMID:17522070 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 decreases expression ISO Tetracycline results in decreased expression of IDH1 mRNA CTD PMID:24489787 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074 		JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 increases expression ISO
EXP		 Tetracycline results in increased expression of IGFBP1 mRNA CTD PMID:17522070 PMID:27089845 NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660 		JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 decreases expression ISO Tetracycline results in decreased expression of IGFBP2 mRNA CTD PMID:24489787 NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 decreases expression ISO Tetracycline results in decreased expression of IGFBP3 mRNA CTD PMID:24489787 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874 		JBrowse link
G IL1B interleukin 1 beta multiple interactions
decreases expression		 EXP
ISO		 Tetracycline analog inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Tetracycline inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Tetracycline inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]
Tetracycline results in decreased expression of IL1B mRNA		 CTD PMID:17267227 PMID:24489787 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 decreases expression ISO Tetracycline results in decreased expression of IL6 mRNA CTD PMID:24489787 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INHBE inhibin subunit beta E increases expression EXP Tetracycline results in increased expression of INHBE mRNA CTD PMID:17175557 NCBI chr12:57,455,307...57,458,025
Ensembl chr12:57,452,323...57,459,280 		JBrowse link
G INPP5F inositol polyphosphate-5-phosphatase F increases expression ISO Tetracycline results in increased expression of INPP5F mRNA CTD PMID:16917069 NCBI chr10:119,726,050...119,829,147
Ensembl chr10:119,726,042...119,829,147 		JBrowse link
G INSIG2 insulin induced gene 2 increases expression ISO Tetracycline results in increased expression of INSIG2 mRNA CTD PMID:16917069 NCBI chr 2:118,088,471...118,110,997
Ensembl chr 2:118,088,452...118,110,997 		JBrowse link
G ISYNA1 inositol-3-phosphate synthase 1 decreases expression ISO Tetracycline results in decreased expression of ISYNA1 mRNA CTD PMID:24489787 NCBI chr19:18,434,388...18,438,133
Ensembl chr19:18,434,388...18,438,167 		JBrowse link
G ITGA3 integrin subunit alpha 3 decreases expression EXP Tetracycline results in decreased expression of ITGA3 mRNA CTD PMID:28882639 NCBI chr17:50,056,110...50,090,481
Ensembl chr17:50,055,968...50,090,481 		JBrowse link
G ITGA5 integrin subunit alpha 5 increases expression EXP Tetracycline results in increased expression of ITGA5 mRNA CTD PMID:28882639 NCBI chr12:54,395,261...54,419,266
Ensembl chr12:54,395,261...54,419,266 		JBrowse link
G ITGAE integrin subunit alpha E increases expression ISO Tetracycline results in increased expression of ITGAE mRNA CTD PMID:16917069 NCBI chr17:3,714,628...3,801,188
Ensembl chr17:3,714,628...3,801,188 		JBrowse link
G ITGAL integrin subunit alpha L decreases expression EXP Tetracycline results in decreased expression of ITGAL mRNA CTD PMID:28882639 NCBI chr16:30,472,742...30,523,185
Ensembl chr16:30,472,658...30,523,567 		JBrowse link
G ITGAM integrin subunit alpha M decreases expression EXP Tetracycline results in decreased expression of ITGAM mRNA CTD PMID:28882639 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 increases expression ISO Tetracycline results in increased expression of JAG1 mRNA CTD PMID:16917069 NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999 		JBrowse link
G JAK1 Janus kinase 1 increases expression ISO Tetracycline results in increased expression of JAK1 mRNA CTD PMID:16917069 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754 		JBrowse link
G KERA keratocan increases expression ISO Tetracycline results in increased expression of KERA mRNA CTD PMID:16917069 NCBI chr12:91,050,491...91,058,024
Ensembl chr12:91,050,491...91,058,024 		JBrowse link
G KRT18 keratin 18 increases expression ISO Tetracycline results in increased expression of KRT18 mRNA CTD PMID:17522070 NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906 		JBrowse link
G KRT8 keratin 8 increases expression ISO Tetracycline results in increased expression of KRT8 mRNA CTD PMID:17522070 NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954 		JBrowse link
G LBP lipopolysaccharide binding protein increases expression ISO Tetracycline results in increased expression of LBP mRNA CTD PMID:17522070 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase decreases expression ISO Tetracycline results in decreased expression of LCAT mRNA CTD PMID:24489787 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131 		JBrowse link
G LGALS3 galectin 3 increases expression ISO Tetracycline results in increased expression of LGALS3 mRNA CTD PMID:17522070 NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423 		JBrowse link
G LIPC lipase C, hepatic type decreases expression ISO Tetracycline results in decreased expression of LIPC mRNA CTD PMID:17522070 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844 		JBrowse link
G LPL lipoprotein lipase increases expression ISO Tetracycline results in increased expression of LPL mRNA CTD PMID:17522070 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259 		JBrowse link
G LRIG3 leucine rich repeats and immunoglobulin like domains 3 increases expression ISO Tetracycline results in increased expression of LRIG3 mRNA CTD PMID:16917069 NCBI chr12:58,872,155...58,920,504
Ensembl chr12:58,872,149...58,920,504 		JBrowse link
G LRP4 LDL receptor related protein 4 decreases expression ISO Tetracycline results in decreased expression of LRP4 mRNA CTD PMID:16917069 NCBI chr11:46,856,717...46,918,550
Ensembl chr11:46,856,717...46,918,642 		JBrowse link
G LRRC4B leucine rich repeat containing 4B increases expression ISO Tetracycline results in increased expression of LRRC4B mRNA CTD PMID:16917069 NCBI chr19:50,516,892...50,568,435
Ensembl chr19:50,516,892...50,568,435 		JBrowse link
G MAL mal, T cell differentiation protein increases expression ISO Tetracycline results in increased expression of MAL mRNA CTD PMID:16917069 NCBI chr 2:95,025,708...95,053,992
Ensembl chr 2:95,025,677...95,053,992 		JBrowse link
G MAOB monoamine oxidase B decreases expression ISO Tetracycline results in decreased expression of MAOB mRNA CTD PMID:17522070 PMID:24489787 NCBI chr  X:43,766,610...43,882,450
Ensembl chr  X:43,766,610...43,882,450 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 decreases phosphorylation EXP Tetracycline results in decreased phosphorylation of MAPK1 protein CTD PMID:25745068 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 decreases phosphorylation EXP Tetracycline results in decreased phosphorylation of MAPK3 protein CTD PMID:25745068 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAT1A methionine adenosyltransferase 1A decreases expression ISO Tetracycline results in decreased expression of MAT1A mRNA CTD PMID:24489787 NCBI chr10:80,271,820...80,289,658
Ensembl chr10:80,271,820...80,289,658 		JBrowse link
G MCPH1 microcephalin 1 increases expression ISO Tetracycline results in increased expression of MCPH1 mRNA CTD PMID:16917069 NCBI chr 8:6,406,627...6,648,508
Ensembl chr 8:6,406,592...6,648,508 		JBrowse link
G ME1 malic enzyme 1 increases expression ISO Tetracycline results in increased expression of ME1 protein CTD PMID:16538043 NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051 		JBrowse link
G MGAT2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase increases expression ISO Tetracycline results in increased expression of MGAT2 mRNA CTD PMID:16917069 NCBI chr14:49,620,799...49,623,481
Ensembl chr14:49,620,799...49,623,481 		JBrowse link
G MIPEP mitochondrial intermediate peptidase decreases expression ISO Tetracycline results in decreased expression of MIPEP mRNA CTD PMID:24489787 NCBI chr13:23,730,189...23,889,400
Ensembl chr13:23,730,189...23,889,400 		JBrowse link
G MIR16-2 microRNA 16-2 increases expression ISO Tetracycline results in increased expression of MIR16 mRNA CTD PMID:17522070 NCBI chr 3:160,404,745...160,404,825
Ensembl chr 3:160,404,745...160,404,825 		JBrowse link
G MMP13 matrix metallopeptidase 13 multiple interactions
decreases activity		 EXP Tetracycline analog inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Tetracycline inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]
Tetracycline analog results in decreased activity of MMP13 protein		 CTD PMID:17267227 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732 		JBrowse link
G MMP2 matrix metallopeptidase 2 decreases activity EXP Tetracycline analog results in decreased activity of MMP2 protein CTD PMID:17267227 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP3 matrix metallopeptidase 3 multiple interactions
decreases expression
decreases activity		 EXP
ISO		 Tetracycline inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]
Tetracycline results in decreased expression of MMP3 mRNA
Tetracycline results in decreased activity of MMP3 protein		 CTD PMID:17267227 PMID:24489787 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MMP8 matrix metallopeptidase 8 decreases activity EXP Tetracycline analog results in decreased activity of MMP8 protein CTD PMID:17267227 NCBI chr11:102,711,796...102,724,954
Ensembl chr11:102,711,796...102,727,050 		JBrowse link
G MRPS12 mitochondrial ribosomal protein S12 increases expression ISO Tetracycline results in increased expression of MRPS12 mRNA CTD PMID:16917069 NCBI chr19:38,930,944...38,933,168
Ensembl chr19:38,930,944...38,933,168 		JBrowse link
G MTMR11 myotubularin related protein 11 increases expression ISO Tetracycline results in increased expression of MTMR11 mRNA CTD PMID:16917069 NCBI chr 1:149,928,651...149,936,879
Ensembl chr 1:149,928,651...149,936,879 		JBrowse link
G MTTP microsomal triglyceride transfer protein decreases expression ISO
EXP		 Tetracycline results in decreased expression of MTTP mRNA CTD PMID:24489787 PMID:27089845 NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression
increases expression		 ISO Tetracycline results in decreased expression of MYC mRNA
Tetracycline results in increased expression of MYC mRNA		 CTD PMID:17202758 PMID:17522070 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G NDRG2 NDRG family member 2 decreases expression ISO Tetracycline results in decreased expression of NDRG2 protein CTD PMID:16538043 NCBI chr14:21,016,763...21,070,872
Ensembl chr14:21,016,763...21,070,872 		JBrowse link
G NEFH neurofilament heavy chain affects expression ISO Tetracycline affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr22:29,480,218...29,491,390
Ensembl chr22:29,480,218...29,491,390 		JBrowse link
G NEU3 neuraminidase 3 increases expression ISO Tetracycline results in increased expression of NEU3 mRNA CTD PMID:16917069 NCBI chr11:74,980,515...75,020,676
Ensembl chr11:74,988,279...75,018,893 		JBrowse link
G NFKBIB NFKB inhibitor beta increases expression ISO Tetracycline results in increased expression of NFKBIB mRNA CTD PMID:17522070 NCBI chr19:38,899,666...38,908,889
Ensembl chr19:38,899,700...38,908,893 		JBrowse link
G NOTCH3 notch receptor 3 decreases expression EXP Tetracycline results in decreased expression of NOTCH3 mRNA CTD PMID:28882639 NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995 		JBrowse link
G NOTCH4 notch receptor 4 decreases expression EXP Tetracycline results in decreased expression of NOTCH4 mRNA CTD PMID:28882639 NCBI chr 6:32,194,843...32,224,067
Ensembl chr 6:32,194,843...32,224,067 		JBrowse link
G NOX4 NADPH oxidase 4 decreases expression ISO Tetracycline results in decreased expression of NOX4 mRNA CTD PMID:24489787 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187 		JBrowse link
G NPM2 nucleophosmin/nucleoplasmin 2 increases expression ISO Tetracycline results in increased expression of NPM2 mRNA CTD PMID:16917069 NCBI chr 8:22,024,134...22,036,897
Ensembl chr 8:22,024,125...22,036,897 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO Tetracycline results in decreased expression of NQO1 mRNA CTD PMID:19224547 PMID:24489787 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 decreases expression ISO Tetracycline results in decreased expression of NR1H4 mRNA CTD PMID:24489787 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 decreases expression ISO Tetracycline results in decreased expression of NR1I3 mRNA CTD PMID:24489787 NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244 		JBrowse link
G NR2E3 nuclear receptor subfamily 2 group E member 3 increases expression ISO Tetracycline results in increased expression of NR2E3 mRNA CTD PMID:16917069 NCBI chr15:71,810,554...71,818,253
Ensembl chr15:71,792,638...71,818,259 		JBrowse link
G NSDHL NAD(P) dependent steroid dehydrogenase-like increases expression ISO Tetracycline results in increased expression of NSDHL mRNA CTD PMID:16917069 NCBI chr  X:152,831,063...152,869,729
Ensembl chr  X:152,830,967...152,869,729 		JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator increases expression EXP Tetracycline results in increased expression of NUPR1 mRNA CTD PMID:17175557 NCBI chr16:28,532,708...28,538,974
Ensembl chr16:28,532,708...28,539,008 		JBrowse link
G ODC1 ornithine decarboxylase 1 increases expression ISO Tetracycline results in increased expression of ODC1 mRNA CTD PMID:17522070 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327 		JBrowse link
G ONECUT1 one cut homeobox 1 decreases expression ISO Tetracycline results in decreased expression of ONECUT1 mRNA CTD PMID:24489787 NCBI chr15:52,755,053...52,790,336
Ensembl chr15:52,755,053...52,791,078 		JBrowse link
G OSBPL3 oxysterol binding protein like 3 decreases expression ISO Tetracycline results in decreased expression of OSBPL3 mRNA CTD PMID:16917069 NCBI chr 7:24,796,537...24,981,845
Ensembl chr 7:24,796,540...24,981,634 		JBrowse link
G OSBPL8 oxysterol binding protein like 8 decreases expression ISO Tetracycline results in decreased expression of OSBPL8 mRNA CTD PMID:16917069 NCBI chr12:76,351,797...76,559,771
Ensembl chr12:76,351,797...76,559,809 		JBrowse link
G OTC ornithine transcarbamylase decreases expression ISO Tetracycline results in decreased expression of OTC mRNA CTD PMID:17522070 PMID:24489787 NCBI chr  X:38,327,684...38,422,928
Ensembl chr  X:38,327,598...38,422,908 		JBrowse link
G PAH phenylalanine hydroxylase decreases expression ISO Tetracycline results in decreased expression of PAH mRNA CTD PMID:24489787 NCBI chr12:102,836,889...102,958,441
Ensembl chr12:102,836,889...102,958,410 		JBrowse link
G PAK2 p21 (RAC1) activated kinase 2 increases expression ISO Tetracycline results in increased expression of PAK2 mRNA CTD PMID:16917069 NCBI chr 3:196,739,857...196,832,647
Ensembl chr 3:196,739,857...196,832,647 		JBrowse link
G PAQR7 progestin and adipoQ receptor family member 7 decreases expression ISO Tetracycline results in decreased expression of PAQR7 mRNA CTD PMID:16917069 NCBI chr 1:25,861,484...25,875,708
Ensembl chr 1:25,861,484...25,875,708 		JBrowse link
G PAQR9 progestin and adipoQ receptor family member 9 increases expression ISO Tetracycline results in increased expression of PAQR9 mRNA CTD PMID:16917069 NCBI chr 3:142,949,164...142,964,008
Ensembl chr 3:142,949,164...142,963,674 		JBrowse link
G PC pyruvate carboxylase increases expression ISO Tetracycline results in increased expression of PCX mRNA CTD PMID:16917069 NCBI chr11:66,848,420...66,958,383
Ensembl chr11:66,848,417...66,958,386 		JBrowse link
G PCDH18 protocadherin 18 increases expression ISO Tetracycline results in increased expression of PCDH18 mRNA CTD PMID:16917069 NCBI chr 4:137,518,918...137,532,494
Ensembl chr 4:137,518,918...137,532,494 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 decreases expression ISO Tetracycline results in decreased expression of PCK1 mRNA CTD PMID:24489787 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121 		JBrowse link
G PCTP phosphatidylcholine transfer protein decreases expression ISO Tetracycline results in decreased expression of PCTP mRNA CTD PMID:16917069 NCBI chr17:55,751,051...55,852,715
Ensembl chr17:55,751,051...55,842,830 		JBrowse link
G PDE4B phosphodiesterase 4B increases expression ISO Tetracycline results in increased expression of PDE4B mRNA CTD PMID:16917069 NCBI chr 1:65,792,510...66,374,579
Ensembl chr 1:65,792,514...66,374,579 		JBrowse link
G PECR peroxisomal trans-2-enoyl-CoA reductase increases expression ISO Tetracycline results in increased expression of PECR mRNA CTD PMID:16917069 NCBI chr 2:216,029,088...216,081,809
Ensembl chr 2:215,996,329...216,082,955 		JBrowse link
G PI4KB phosphatidylinositol 4-kinase beta increases expression ISO Tetracycline results in increased expression of PI4KB mRNA CTD PMID:16917069 NCBI chr 1:151,291,797...151,327,715
Ensembl chr 1:151,291,797...151,327,715 		JBrowse link
G PIK3C2A phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha increases expression ISO Tetracycline results in increased expression of PIK3C2A mRNA CTD PMID:16917069 NCBI chr11:17,086,575...17,207,986
Ensembl chr11:17,077,730...17,207,986 		JBrowse link
G PIK3C2G phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma increases expression ISO Tetracycline results in increased expression of PIK3C2G mRNA CTD PMID:16917069 NCBI chr12:18,242,961...18,726,817
Ensembl chr12:18,242,961...18,648,416 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha increases expression ISO Tetracycline results in increased expression of PIK3CA mRNA CTD PMID:16917069 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta increases expression ISO Tetracycline results in increased expression of PIK3CB mRNA CTD PMID:16917069 NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,698...138,834,928 		JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta decreases expression ISO Tetracycline results in decreased expression of PIK3CD mRNA CTD PMID:16917069 NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,729,114 		JBrowse link
G PIP4K2B phosphatidylinositol-5-phosphate 4-kinase type 2 beta decreases expression ISO Tetracycline results in decreased expression of PIP4K2B mRNA CTD PMID:16917069 NCBI chr17:38,765,691...38,799,556
Ensembl chr17:38,765,691...38,800,126 		JBrowse link
G PIP5K1A phosphatidylinositol-4-phosphate 5-kinase type 1 alpha increases expression ISO Tetracycline results in increased expression of PIP5K1A mRNA CTD PMID:16917069 NCBI chr 1:151,195,419...151,249,531
Ensembl chr 1:151,197,949...151,249,536 		JBrowse link
G PIP5K1B phosphatidylinositol-4-phosphate 5-kinase type 1 beta increases expression ISO Tetracycline results in increased expression of PIP5K1B mRNA CTD PMID:16917069 NCBI chr 9:68,705,240...69,009,176
Ensembl chr 9:68,705,240...69,009,176 		JBrowse link
G PITPNA phosphatidylinositol transfer protein alpha increases expression ISO Tetracycline results in increased expression of PITPNA mRNA CTD PMID:16917069 NCBI chr17:1,517,718...1,562,792
Ensembl chr17:1,517,718...1,562,792 		JBrowse link
G PKD1L3 polycystin 1 like 3, transient receptor potential channel interacting increases expression ISO Tetracycline results in increased expression of PKD1L3 mRNA CTD PMID:16917069 NCBI chr16:71,929,538...72,000,402
Ensembl chr16:71,929,538...72,000,402 		JBrowse link
G PKLR pyruvate kinase L/R decreases expression ISO Tetracycline results in decreased expression of PKLR mRNA CTD PMID:17522070 PMID:19224547 NCBI chr 1:155,289,293...155,308,654
Ensembl chr 1:155,289,293...155,301,438 		JBrowse link
G PLA2G2A phospholipase A2 group IIA decreases expression ISO Tetracycline results in decreased expression of PLA2G2A mRNA CTD PMID:16917069 NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416 		JBrowse link
G PLA2G2D phospholipase A2 group IID decreases expression ISO Tetracycline results in decreased expression of PLA2G2D mRNA CTD PMID:16917069 NCBI chr 1:20,111,939...20,119,536
Ensembl chr 1:20,111,939...20,119,566 		JBrowse link
G PLCG1 phospholipase C gamma 1 increases expression ISO Tetracycline results in increased expression of PLCG1 mRNA CTD PMID:16917069 NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801 		JBrowse link
G PLCZ1 phospholipase C zeta 1 increases expression ISO Tetracycline results in increased expression of PLCZ1 mRNA CTD PMID:16917069 NCBI chr12:18,645,609...18,738,012
Ensembl chr12:18,683,169...18,738,100 		JBrowse link
G PLD1 phospholipase D1 increases expression ISO Tetracycline results in increased expression of PLD1 mRNA CTD PMID:16917069 NCBI chr 3:171,600,404...171,810,483
Ensembl chr 3:171,600,404...171,810,950 		JBrowse link
G PLG plasminogen increases expression ISO Tetracycline results in increased expression of PLG mRNA CTD PMID:16917069 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097 		JBrowse link
G PLSCR4 phospholipid scramblase 4 increases expression ISO Tetracycline results in increased expression of PLSCR4 mRNA CTD PMID:16917069 NCBI chr 3:146,192,335...146,251,105
Ensembl chr 3:146,192,335...146,251,179 		JBrowse link
G POLR2A RNA polymerase II subunit A increases expression ISO Tetracycline results in increased expression of POLR2A mRNA CTD PMID:16917069 NCBI chr17:7,484,366...7,514,616
Ensembl chr17:7,484,366...7,514,616 		JBrowse link
G POMC proopiomelanocortin increases expression ISO Tetracycline results in increased expression of POMC mRNA CTD PMID:16917069 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions
decreases expression		 ISO bicyclol inhibits the reaction [Tetracycline results in decreased expression of PPARA mRNA] CTD PMID:19224547 PMID:19427351 PMID:24489787 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPP1R3C protein phosphatase 1 regulatory subunit 3C increases expression ISO Tetracycline results in increased expression of PPP1R3C mRNA CTD PMID:16917069 NCBI chr10:91,628,442...91,633,071
Ensembl chr10:91,628,442...91,633,071 		JBrowse link
G PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2 increases expression ISO Tetracycline results in increased expression of PRKAB2 mRNA CTD PMID:16917069 NCBI chr 1:147,155,106...147,172,470
Ensembl chr 1:147,155,106...147,172,550 		JBrowse link
G PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2 increases expression ISO Tetracycline results in increased expression of PRKAG2 mRNA CTD PMID:16917069 NCBI chr 7:151,556,127...151,877,115
Ensembl chr 7:151,556,124...151,877,214 		JBrowse link
G PRNP prion protein (Kanno blood group) affects binding
multiple interactions		 EXP Tetracycline binds to PRNP protein
Tetracycline inhibits the reaction [PRNP protein binds to PRNP protein]		 CTD PMID:10903871 NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590 		JBrowse link
G PTEN phosphatase and tensin homolog increases expression ISO Tetracycline results in increased expression of PTEN mRNA CTD PMID:16917069 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGDS prostaglandin D2 synthase increases expression ISO Tetracycline results in increased expression of PTGDS mRNA CTD PMID:16917069 NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Tetracycline results in decreased expression of PTGS2 mRNA CTD PMID:24489787 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTMA prothymosin alpha increases expression ISO Tetracycline results in increased expression of PTMA mRNA CTD PMID:17522070 NCBI chr 2:231,708,525...231,713,551
Ensembl chr 2:231,706,895...231,713,551 		JBrowse link
G PTPMT1 protein tyrosine phosphatase mitochondrial 1 decreases expression ISO Tetracycline results in decreased expression of PTPMT1 mRNA CTD PMID:16917069 NCBI chr11:47,565,599...47,573,461
Ensembl chr11:47,565,430...47,573,461 		JBrowse link
G PTPN7 protein tyrosine phosphatase non-receptor type 7 increases expression ISO Tetracycline results in increased expression of PTPN7 mRNA CTD PMID:16917069 NCBI chr 1:202,147,013...202,161,588
Ensembl chr 1:202,147,013...202,161,588 		JBrowse link
G PVR PVR cell adhesion molecule increases expression ISO Tetracycline results in increased expression of PVR mRNA CTD PMID:17522070 NCBI chr19:44,643,910...44,666,162
Ensembl chr19:44,643,798...44,666,162 		JBrowse link
G PYGL glycogen phosphorylase L decreases expression ISO Tetracycline results in decreased expression of PYGL mRNA CTD PMID:17522070 NCBI chr14:50,905,217...50,944,483
Ensembl chr14:50,857,891...50,944,483 		JBrowse link
G RAB35 RAB35, member RAS oncogene family increases expression ISO Tetracycline results in increased expression of RAB35 mRNA CTD PMID:16917069 NCBI chr12:120,095,099...120,116,753
Ensembl chr12:120,095,099...120,117,502 		JBrowse link
G RAPGEF5 Rap guanine nucleotide exchange factor 5 increases expression ISO Tetracycline results in increased expression of RAPGEF5 mRNA CTD PMID:16917069 NCBI chr 7:22,118,236...22,357,154
Ensembl chr 7:22,118,236...22,357,154 		JBrowse link
G RDH16 retinol dehydrogenase 16 decreases expression ISO Tetracycline results in decreased expression of RDH16 mRNA CTD PMID:16917069 NCBI chr12:56,951,431...56,957,608
Ensembl chr12:56,951,431...56,959,374 		JBrowse link
G RGN regucalcin decreases expression ISO Tetracycline results in decreased expression of RGN mRNA CTD PMID:12883083 NCBI chr  X:47,078,443...47,093,313
Ensembl chr  X:47,078,355...47,093,314 		JBrowse link
G RNPEP arginyl aminopeptidase increases expression ISO Tetracycline results in increased expression of RNPEP mRNA CTD PMID:16917069 NCBI chr 1:201,982,648...202,006,143
Ensembl chr 1:201,982,372...202,006,147 		JBrowse link
G RPL23 ribosomal protein L23 increases expression ISO Tetracycline results in increased expression of RPL23 mRNA CTD PMID:16917069 NCBI chr17:38,847,860...38,853,721
Ensembl chr17:38,847,860...38,853,764 		JBrowse link
G RPS6KA2 ribosomal protein S6 kinase A2 increases expression ISO Tetracycline results in increased expression of RPS6KA2 mRNA CTD PMID:16917069 NCBI chr 6:166,409,364...166,862,773
Ensembl chr 6:166,409,364...166,906,451 		JBrowse link
G RXRG retinoid X receptor gamma increases expression ISO Tetracycline results in increased expression of RXRG mRNA CTD PMID:16917069 NCBI chr 1:165,400,922...165,445,126
Ensembl chr 1:165,400,922...165,445,355 		JBrowse link
G S100A8 S100 calcium binding protein A8 increases expression ISO Tetracycline results in increased expression of S100A8 mRNA CTD PMID:17522070 NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073 		JBrowse link
G S100A9 S100 calcium binding protein A9 increases expression ISO Tetracycline results in increased expression of S100A9 mRNA CTD PMID:17522070 NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023 		JBrowse link
G SACM1L SAC1 like phosphatidylinositide phosphatase increases expression ISO Tetracycline results in increased expression of SACM1L mRNA CTD PMID:16917069 NCBI chr 3:45,689,396...45,745,409
Ensembl chr 3:45,689,056...45,745,412 		JBrowse link
G SARDH sarcosine dehydrogenase decreases expression ISO Tetracycline results in decreased expression of SARDH mRNA CTD PMID:24489787 NCBI chr 9:133,659,418...133,739,955
Ensembl chr 9:133,663,560...133,739,955 		JBrowse link
G SCD stearoyl-CoA desaturase decreases expression ISO Tetracycline results in decreased expression of SCD mRNA CTD PMID:17202758 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826 		JBrowse link
G SDR9C7 short chain dehydrogenase/reductase family 9C member 7 increases expression ISO Tetracycline results in increased expression of SDR9C7 mRNA CTD PMID:16917069 NCBI chr12:56,923,133...56,934,408
Ensembl chr12:56,923,133...56,934,408 		JBrowse link
G SEC14L4 SEC14 like lipid binding 4 increases expression ISO Tetracycline results in increased expression of SEC14L4 mRNA CTD PMID:16917069 NCBI chr22:30,488,902...30,505,695
Ensembl chr22:30,488,902...30,505,711 		JBrowse link
G SEMA6D semaphorin 6D increases expression ISO Tetracycline results in increased expression of SEMA6D mRNA CTD PMID:16917069 NCBI chr15:47,184,089...47,774,228
Ensembl chr15:47,184,101...47,774,228 		JBrowse link
G SERPINA3 serpin family A member 3 increases expression EXP Tetracycline results in increased expression of SERPINA3 mRNA CTD PMID:17175557 NCBI chr14:94,612,391...94,624,053
Ensembl chr14:94,612,384...94,624,055 		JBrowse link
G SGMS1 sphingomyelin synthase 1 increases expression ISO Tetracycline results in increased expression of SGMS1 mRNA CTD PMID:16917069 NCBI chr10:50,305,600...50,625,184
Ensembl chr10:50,305,586...50,625,163 		JBrowse link
G SLC10A1 solute carrier family 10 member 1 decreases expression ISO Tetracycline results in decreased expression of SLC10A1 mRNA CTD PMID:24489787 PMID:27765674 NCBI chr14:69,775,416...69,797,241
Ensembl chr14:69,775,416...69,797,241 		JBrowse link
G SLC10A2 solute carrier family 10 member 2 decreases expression ISO Tetracycline results in decreased expression of SLC10A2 mRNA CTD PMID:24489787 NCBI chr13:103,043,998...103,066,417
Ensembl chr13:103,043,998...103,066,417 		JBrowse link
G SLC16A7 solute carrier family 16 member 7 decreases expression ISO Tetracycline results in decreased expression of SLC16A7 mRNA CTD PMID:24489787 NCBI chr12:59,596,029...59,789,841
Ensembl chr12:59,596,029...59,789,855 		JBrowse link
G SLC1A4 solute carrier family 1 member 4 increases expression ISO Tetracycline results in increased expression of SLC1A4 mRNA CTD PMID:16917069 NCBI chr 2:64,988,479...65,023,865
Ensembl chr 2:64,988,477...65,023,865 		JBrowse link
G SLC22A6 solute carrier family 22 member 6 increases export
multiple interactions
increases uptake		 EXP SLC22A6 protein results in increased export of Tetracycline
Tetracycline inhibits the reaction [SLC22A6 protein results in increased uptake of Anions]
SLC22A6 protein results in increased uptake of Tetracycline		 CTD PMID:11855680 NCBI chr11:62,976,597...62,984,967
Ensembl chr11:62,936,385...62,984,967 		JBrowse link
G SLC22A7 solute carrier family 22 member 7 multiple interactions
increases uptake
increases transport		 EXP Acetaminophen inhibits the reaction [SLC22A7 protein results in increased transport of Tetracycline]; Bumetanide inhibits the reaction [SLC22A7 protein results in increased transport of Tetracycline]; Chloramphenicol inhibits the reaction [SLC22A7 protein results in increased transport of Tetracycline]; Diclofenac inhibits the reaction [SLC22A7 protein results in increased transport of Tetracycline]; Erythromycin inhibits the reaction [SLC22A7 protein results in increased transport of Tetracycline]; Furosemide inhibits the reaction [SLC22A7 protein results in increased transport of Tetracycline]; Ibuprofen inhibits the reaction [SLC22A7 protein results in increased transport of Tetracycline]; Indomethacin inhibits the reaction [SLC22A7 protein results in increased transport of Tetracycline]; Tetracycline inhibits the reaction [SLC22A7 protein results in increased uptake of Anions]
SLC22A7 protein results in increased uptake of Tetracycline		 CTD PMID:11855680 PMID:15901346 NCBI chr 6:43,295,714...43,305,538
Ensembl chr 6:43,295,694...43,305,538 		JBrowse link
G SLC22A8 solute carrier family 22 member 8 increases uptake EXP SLC22A8 protein results in increased uptake of Tetracycline CTD PMID:11855680 NCBI chr11:62,992,824...63,015,841
Ensembl chr11:62,989,154...63,015,841 		JBrowse link
G SLC22A9 solute carrier family 22 member 9 increases export
multiple interactions
increases uptake		 EXP SLC22A9 protein results in increased export of Tetracycline
Tetracycline inhibits the reaction [SLC22A9 protein results in increased uptake of Anions]
SLC22A9 protein results in increased uptake of Tetracycline		 CTD PMID:11855680 NCBI chr11:63,369,785...63,410,294
Ensembl chr11:63,369,785...63,410,294 		JBrowse link
G SLC25A15 solute carrier family 25 member 15 decreases expression ISO Tetracycline results in decreased expression of SLC25A15 mRNA CTD PMID:24489787 NCBI chr13:40,789,611...40,812,460
Ensembl chr13:40,789,412...40,812,460 		JBrowse link
G SLC25A17 solute carrier family 25 member 17 decreases expression ISO Tetracycline results in decreased expression of SLC25A17 mRNA CTD PMID:24489787 NCBI chr22:40,769,630...40,819,346
Ensembl chr22:40,769,630...40,819,399 		JBrowse link
G SLC25A20 solute carrier family 25 member 20 decreases expression ISO Tetracycline results in decreased expression of SLC25A20 mRNA CTD PMID:24489787 NCBI chr 3:48,856,926...48,898,882
Ensembl chr 3:48,856,926...48,898,904 		JBrowse link
G SLC25A30 solute carrier family 25 member 30 increases expression ISO Tetracycline results in increased expression of SLC25A30 mRNA CTD PMID:16917069 NCBI chr13:45,393,316...45,434,016
Ensembl chr13:45,393,316...45,418,455 		JBrowse link
G SLC27A2 solute carrier family 27 member 2 decreases expression ISO Tetracycline results in decreased expression of SLC27A2 mRNA CTD PMID:24489787 NCBI chr15:50,182,196...50,236,385
Ensembl chr15:50,182,196...50,236,385 		JBrowse link
G SLC27A5 solute carrier family 27 member 5 increases expression
decreases expression		 ISO Tetracycline results in increased expression of SLC27A5 mRNA
Tetracycline results in decreased expression of SLC27A5 protein		 CTD PMID:25745068 NCBI chr19:58,498,333...58,511,992
Ensembl chr19:58,479,512...58,512,413 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 increases expression ISO Tetracycline results in increased expression of SLC2A1 mRNA CTD PMID:17522070 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 decreases expression ISO Tetracycline results in decreased expression of SLC2A2 mRNA CTD PMID:24489787 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743 		JBrowse link
G SLC2A3 solute carrier family 2 member 3 increases expression ISO Tetracycline results in increased expression of SLC2A3 mRNA CTD PMID:19224547 NCBI chr12:7,919,230...7,936,187
Ensembl chr12:7,919,230...8,019,007 		JBrowse link
G SLC2A5 solute carrier family 2 member 5 decreases expression ISO Tetracycline results in decreased expression of SLC2A5 mRNA CTD PMID:19224547 NCBI chr 1:9,035,106...9,094,195
Ensembl chr 1:9,035,106...9,088,478 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 decreases expression ISO Tetracycline results in decreased expression of SLCO1B2 mRNA CTD PMID:17522070 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
G SORL1 sortilin related receptor 1 decreases expression ISO Tetracycline results in decreased expression of SORL1 mRNA CTD PMID:16917069 NCBI chr11:121,452,314...121,633,763
Ensembl chr11:121,452,314...121,633,763 		JBrowse link
G SPIN2B spindlin family member 2B decreases expression ISO Tetracycline results in decreased expression of SPIN2B mRNA CTD PMID:17522070 NCBI chr  X:57,119,682...57,121,548
Ensembl chr  X:57,118,551...57,121,548 		JBrowse link
G SPP1 secreted phosphoprotein 1 increases expression ISO Tetracycline results in increased expression of SPP1 mRNA CTD PMID:16917069 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 increases expression ISO Tetracycline results in increased expression of SPTLC1 mRNA CTD PMID:16917069 NCBI chr 9:92,031,147...92,115,413
Ensembl chr 9:92,000,087...92,115,413 		JBrowse link
G SPTLC3 serine palmitoyltransferase long chain base subunit 3 increases expression ISO Tetracycline results in increased expression of SPTLC3 mRNA CTD PMID:16917069 NCBI chr20:13,008,972...13,169,103
Ensembl chr20:13,008,972...13,169,103 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 increases expression
decreases expression		 ISO
EXP		 Tetracycline results in increased expression of SREBF1 mRNA
Tetracycline results in decreased expression of SREBF1 mRNA		 CTD PMID:16917069 PMID:17202758 PMID:17522070 PMID:24469900 PMID:27089845 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 increases expression ISO Tetracycline results in increased expression of ST3GAL1 mRNA CTD PMID:16917069 NCBI chr 8:133,454,848...133,571,887
Ensembl chr 8:133,454,848...133,571,926 		JBrowse link
G ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 increases expression ISO Tetracycline results in increased expression of ST3GAL4 mRNA CTD PMID:16917069 NCBI chr11:126,355,686...126,414,638
Ensembl chr11:126,355,640...126,440,344 		JBrowse link
G STAM signal transducing adaptor molecule increases expression ISO Tetracycline results in increased expression of STAM mRNA CTD PMID:16917069 NCBI chr10:17,644,151...17,716,824
Ensembl chr10:17,644,151...17,716,824 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 increases expression ISO Tetracycline results in increased expression of STAT3 mRNA CTD PMID:17522070 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G SULT2B1 sulfotransferase family 2B member 1 increases expression ISO Tetracycline results in increased expression of SULT2B1 mRNA CTD PMID:16917069 NCBI chr19:48,552,172...48,599,427
Ensembl chr19:48,552,172...48,599,425 		JBrowse link
G TAGLN transgelin decreases expression EXP Tetracycline results in decreased expression of TAGLN mRNA CTD PMID:17175557 NCBI chr11:117,199,294...117,207,465
Ensembl chr11:117,199,370...117,207,464 		JBrowse link
G TAT tyrosine aminotransferase decreases expression ISO Tetracycline results in decreased expression of TAT mRNA CTD PMID:24489787 NCBI chr16:71,565,660...71,577,092
Ensembl chr16:71,565,660...71,577,092 		JBrowse link
G TF transferrin decreases expression ISO Tetracycline results in decreased expression of TF protein CTD PMID:16538043 NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641 		JBrowse link
G THRSP thyroid hormone responsive decreases expression ISO Tetracycline results in decreased expression of THRSP mRNA CTD PMID:16917069 PMID:17522070 NCBI chr11:78,063,861...78,068,351
Ensembl chr11:78,063,861...78,068,351 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 increases expression ISO Tetracycline results in increased expression of TIMP1 mRNA CTD PMID:17522070 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A increases expression ISO Tetracycline results in increased expression of TNFRSF1A mRNA CTD PMID:17522070 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TOP2A DNA topoisomerase II alpha decreases expression ISO
EXP		 Tetracycline results in decreased expression of TOP2A mRNA
Tetracycline results in decreased expression of TOP2A protein		 CTD PMID:19224547 PMID:23293027 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
G TP53 tumor protein p53 increases expression ISO Tetracycline results in increased expression of TP53 mRNA CTD PMID:17522070 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TSPO translocator protein decreases expression ISO Tetracycline results in decreased expression of TSPO mRNA CTD PMID:16917069 NCBI chr22:43,151,559...43,163,242
Ensembl chr22:43,151,547...43,163,242 		JBrowse link
G TTC1 tetratricopeptide repeat domain 1 increases expression ISO Tetracycline results in increased expression of TTC1 mRNA CTD PMID:16917069 NCBI chr 5:160,009,139...160,065,543
Ensembl chr 5:160,009,113...160,065,543 		JBrowse link
G TTR transthyretin decreases expression ISO Tetracycline results in decreased expression of TTR mRNA CTD PMID:17522070 NCBI chr18:31,591,877...31,598,821
Ensembl chr18:31,557,009...31,598,833 		JBrowse link
G TUT1 terminal uridylyl transferase 1, U6 snRNA-specific increases expression ISO Tetracycline results in increased expression of TUT1 mRNA CTD PMID:16917069 NCBI chr11:62,575,052...62,591,523
Ensembl chr11:62,575,045...62,591,637 		JBrowse link
G TXN thioredoxin increases expression ISO Tetracycline results in increased expression of TXN mRNA CTD PMID:17522070 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G TXNRD1 thioredoxin reductase 1 increases expression
decreases expression		 ISO Tetracycline results in increased expression of TXNRD1 mRNA
Tetracycline results in decreased expression of TXNRD1 mRNA		 CTD PMID:17522070 PMID:19224547 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307 		JBrowse link
G UGCG UDP-glucose ceramide glucosyltransferase increases expression ISO Tetracycline results in increased expression of UGCG mRNA CTD PMID:16917069 NCBI chr 9:111,896,814...111,935,369
Ensembl chr 9:111,896,814...111,935,369 		JBrowse link
G UGT1A6 UDP glucuronosyltransferase family 1 member A6 decreases expression ISO Tetracycline results in decreased expression of UGT1A6 mRNA CTD PMID:19224547 NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300 		JBrowse link
G UGT2A3 UDP glucuronosyltransferase family 2 member A3 increases expression ISO Tetracycline results in increased expression of UGT2A3 mRNA CTD PMID:16917069 NCBI chr 4:68,928,463...68,951,804
Ensembl chr 4:68,928,463...68,951,804 		JBrowse link
G UGT3A1 UDP glycosyltransferase family 3 member A1 increases expression ISO Tetracycline results in increased expression of UGT3A1 mRNA CTD PMID:16917069 NCBI chr 5:35,951,006...36,001,022
Ensembl chr 5:35,951,006...36,001,028 		JBrowse link
G UGT3A2 UDP glycosyltransferase family 3 member A2 increases expression ISO Tetracycline results in increased expression of UGT3A2 mRNA CTD PMID:16917069 NCBI chr 5:36,035,021...36,066,882
Ensembl chr 5:36,035,021...36,071,358 		JBrowse link
G WIPI1 WD repeat domain, phosphoinositide interacting 1 increases expression EXP Tetracycline results in increased expression of WIPI1 mRNA CTD PMID:17175557 NCBI chr17:68,421,281...68,457,496
Ensembl chr17:68,420,948...68,457,513 		JBrowse link
G ZIC5 Zic family member 5 increases expression ISO Tetracycline results in increased expression of ZIC5 mRNA CTD PMID:16917069 NCBI chr13:99,962,964...99,971,909
Ensembl chr13:99,962,964...99,971,767 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    role 25956
      biological role 25935
        antimicrobial agent 21917
          tetracycline 383
            11a-hydroxytetracycline 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26040
    subatomic particle 26015
      composite particle 26015
        hadron 26015
          baryon 26015
            nucleon 26015
              atomic nucleus 26015
                atom 26015
                  main group element atom 25840
                    main group molecular entity 25840
                      s-block molecular entity 25160
                        hydrogen molecular entity 24758
                          hydrides 22970
                            organic hydride 21930
                              organic fundamental parent 21930
                                hydrocarbon 21357
                                  cyclic hydrocarbon 19996
                                    arene 19976
                                      polycyclic arene 19670
                                        ortho-fused polycyclic arene 10287
                                          acene 8272
                                            tetracene 8267
                                              tetracyclines 514
                                                tetracycline 383
                                                  11a-hydroxytetracycline 0
paths to the root