Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Neu3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of NEU3 mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of NEU3 mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NEU3 mRNA | CTD | PMID:33387578 | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:32109520 | 4,4'-diaminodiphenylmethane | affects expression | ISO | Neu3 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane affects the expression of NEU3 mRNA | CTD | PMID:18648102 | 6-propyl-2-thiouracil | decreases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of NEU3 mRNA | CTD | PMID:30047161 | acrylamide | decreases expression | ISO | Neu3 (Mus musculus) | 6480464 | Acrylamide results in decreased expression of NEU3 mRNA | CTD | PMID:30807115 | all-trans-retinoic acid | affects expression | ISO | Neu3 (Mus musculus) | 6480464 | Tretinoin affects the expression of NEU3 mRNA | CTD | PMID:34627992 | all-trans-retinoic acid | increases expression | ISO | Neu3 (Mus musculus) | 6480464 | Tretinoin results in increased expression of NEU3 mRNA | CTD | PMID:36189433 | all-trans-retinoic acid | multiple interactions | ISO | Neu3 (Mus musculus) | 6480464 | 3 more ... | CTD | PMID:34627992 and PMID:36189433 | amitrole | decreases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of NEU3 mRNA | CTD | PMID:30047161 | ammonium chloride | affects expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of NEU3 mRNA | CTD | PMID:16483693 | amphetamine | decreases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of NEU3 mRNA | CTD | PMID:30779732 | aristolochic acid A | increases expression | EXP | | 6480464 | aristolochic acid I results in increased expression of NEU3 mRNA | CTD | PMID:33212167 | arsenous acid | increases expression | EXP | | 6480464 | Arsenic Trioxide results in increased expression of NEU3 mRNA | CTD | PMID:15070760 | benzene-1,2,4-triol | increases expression | EXP | | 6480464 | hydroxyhydroquinone results in increased expression of NEU3 mRNA | CTD | PMID:23776099 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of NEU3 mRNA | CTD | PMID:20498004 | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of NEU3 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | Neu3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of NEU3 mRNA | CTD | PMID:19770486 | bisphenol A | increases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of NEU3 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of NEU3 mRNA | CTD | PMID:36232920 | caffeine | increases phosphorylation | EXP | | 6480464 | Caffeine results in increased phosphorylation of NEU3 protein | CTD | PMID:35688186 | carbon nanotube | increases expression | ISO | Neu3 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of NEU3 mRNA | CTD | PMID:25620056 | catechol | increases expression | EXP | | 6480464 | catechol results in increased expression of NEU3 mRNA | CTD | PMID:23776099 | chlorpyrifos | decreases expression | ISO | Neu3 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of NEU3 mRNA | CTD | PMID:37019170 | cisplatin | multiple interactions | EXP | | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of NEU3 mRNA | CTD | PMID:27392435 | cisplatin | increases expression | EXP | | 6480464 | Cisplatin results in increased expression of NEU3 mRNA | CTD | PMID:27392435 | diarsenic trioxide | increases expression | EXP | | 6480464 | Arsenic Trioxide results in increased expression of NEU3 mRNA | CTD | PMID:15070760 | Dicyclohexyl phthalate | multiple interactions | ISO | Neu3 (Mus musculus) | 6480464 | [dicyclohexyl phthalate results in increased activity of NR1I2 protein] which results in increased expression of NEU3 mRNA | CTD | PMID:34851150 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of NEU3 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of NEU3 mRNA | CTD | PMID:29391264 | flavonoids | decreases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | Flavonoids results in decreased expression of NEU3 mRNA | CTD | PMID:18035473 | FR900359 | decreases phosphorylation | EXP | | 6480464 | FR900359 results in decreased phosphorylation of NEU3 protein | CTD | PMID:37730182 | gentamycin | decreases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of NEU3 mRNA | CTD | PMID:33387578 | hydroquinone | increases expression | EXP | | 6480464 | hydroquinone results in increased expression of NEU3 mRNA | CTD | PMID:23776099 | indole-3-methanol | affects expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | indole-3-carbinol affects the expression of NEU3 mRNA | CTD | PMID:21396975 | leflunomide | decreases expression | EXP | | 6480464 | leflunomide results in decreased expression of NEU3 mRNA | CTD | PMID:28988120 | methimazole | decreases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of NEU3 mRNA | CTD | PMID:30047161 | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | Neu3 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NEU3 mRNA | CTD | PMID:36189433 | monosodium L-glutamate | increases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | Sodium Glutamate results in increased expression of NEU3 mRNA | CTD | PMID:20928830 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of NEU3 mRNA | CTD | PMID:22230336 | paracetamol | increases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of NEU3 mRNA | CTD | PMID:33387578 | pirinixic acid | multiple interactions | ISO | Neu3 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of NEU3 mRNA | CTD | PMID:19710929 | progesterone | increases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | Progesterone results in increased expression of NEU3 mRNA | CTD | PMID:20726854 | propiconazole | decreases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | propiconazole results in decreased expression of NEU3 mRNA | CTD | PMID:30047161 | sodium arsenite | affects methylation | EXP | | 6480464 | sodium arsenite affects the methylation of NEU3 gene | CTD | PMID:28589171 | sodium arsenite | decreases expression | ISO | Neu3 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of NEU3 mRNA | CTD | PMID:36209798 and PMID:37682722 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of NEU3 mRNA | CTD | PMID:34032870 | sulfadimethoxine | decreases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of NEU3 mRNA | CTD | PMID:30047161 | sunitinib | decreases expression | EXP | | 6480464 | Sunitinib results in decreased expression of NEU3 mRNA | CTD | PMID:31533062 | tetrachloromethane | affects expression | ISO | Neu3 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of NEU3 mRNA | CTD | PMID:17484886 | tetracycline | increases expression | ISO | Neu3 (Mus musculus) | 6480464 | Tetracycline results in increased expression of NEU3 mRNA | CTD | PMID:16917069 | thioacetamide | decreases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of NEU3 mRNA | CTD | PMID:34492290 | tributylstannane | decreases expression | ISO | Neu3 (Mus musculus) | 6480464 | tributyltin results in decreased expression of NEU3 mRNA | CTD | PMID:31939706 | triptonide | increases expression | ISO | Neu3 (Mus musculus) | 6480464 | triptonide results in increased expression of NEU3 mRNA | CTD | PMID:33045310 | urethane | decreases expression | EXP | | 6480464 | Urethane results in decreased expression of NEU3 mRNA | CTD | PMID:28818685 | vinclozolin | decreases expression | ISO | Neu3 (Rattus norvegicus) | 6480464 | vinclozolin results in decreased expression of NEU3 mRNA | CTD | PMID:23034163 | |