Gene: RPS6KA2 (ribosomal protein S6 kinase, 90kDa, polypeptide 2)  Homo sapiens

Symbol: RPS6KA2
Name: ribosomal protein S6 kinase, 90kDa, polypeptide 2
Description: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 90 kDa ribosomal protein S6 kinase 2; HU-2; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1c; MAPKAP kinase 1c; MAPKAPK-1c; MAPKAPK1C; OTTHUMP00000017601; OTTHUMP00000219225; OTTHUMP00000219226; OTTHUMP00000219227; OTTHUMP00000219228; p90-RSK 2; p90-RSK3; p90RSK2; pp90RSK3; ribosomal protein S6 kinase alpha 2; ribosomal protein S6 kinase alpha-2; ribosomal S6 kinase 3; RSK; RSK-3; RSK3; S6K-alpha; S6K-alpha-2; S6K-alpha2
Orthologs: Mus musculus : Rps6ka2 (ribosomal protein S6 kinase, polypeptide 2)  MGI
Rattus norvegicus : Rps6ka2 (ribosomal protein S6 kinase polypeptide 2)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_16166,833,535 - 167,286,550-NCBI
Human Genome Assembly HuRef6164,294,243 - 164,748,630-NCBI
Human Genome Assembly GRCh376166,822,854 - 167,275,771-NCBI
Human Genome Assembly Build 366166,742,844 - 167,195,761-NCBI
Human Cytogenetic Map6q27 NCBI
Human Genome Assembly6166,793,264 - 167,011,137 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on RPS6KA2
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1348784
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2013-03-06
Status: ACTIVE