| 1322948 | Prrx2 | paired related homeobox 2 | Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; HMG box domain binding activity; and RNA polymerase II general transcription initiation factor activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including embryonic morphogenesis; positive regulation of cell population proliferation; and positive regulation of smoothened signaling pathway. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; branchial arch; embryo mesenchyme; and genitourinary system. Orthologous to human PRRX2 (paired related homeobox 2). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 30735076 | 30771263 | Mouse | 218 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 62203 | Rps8 | ribosomal protein S8 | A structural constituent of ribosome. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Part of cytosolic small ribosomal subunit. Is expressed in brain; cerebral cortex ventricular layer; and cortical plate. Orthologous to human RP S8 (ribosomal protein S8). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 117011033 | 117013329 | Mouse | 145 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1619504 | Rps8-ps1 | ribosomal protein S8, pseudogene 1 | | 10 | 56230505 | 56231196 | Mouse | | symbol , PhenoGen , name | gene, pseudo, INFERRED [RefSeq] |
| 2294013 | Rps8-ps2 | ribosomal protein S8, pseudogene 2 | INTERACTS WITH cantharidin | 2 | 175596738 | 175597425 | Mouse | 1 | symbol , PhenoGen , name | gene, pseudo, INFERRED [RefSeq] |
| 2309722 | Rps8-ps3 | ribosomal protein S8, pseudogene 3 | | 6 | 52095201 | 52095915 | Mouse | | symbol , PhenoGen , name | gene, pseudo, INFERRED [RefSeq] |
| 5146615 | Rps8-ps4 | ribosomal protein S8, pseudogene 4 | INTERACTS WITH 1,4-dioxane | 7 | 13066532 | 13067210 | Mouse | 1 | symbol , PhenoGen , name | gene, pseudo, INFERRED [RefSeq] |
| 2294674 | Rps8-ps5 | ribosomal protein S8, pseudogene 5 | | 2 | 177534408 | 177535095 | Mouse | | symbol , PhenoGen , name | gene, pseudo, INFERRED [RefSeq] |
| 1319780 | Ndufs8 | NADH:ubiquinone oxidoreductase core subunit S8 | Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly; and response to oxidative stress. Located in mit ochondrion. Part of respiratory chain complex I. Is active in mitochondrial inner membrane. Is expressed in several structures, including early conceptus and oocyte. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 2. Orthologous to human NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8). [provided by Alliance of Genome Resources, Apr 2025] | 19 | 3958863 | 3962774 | Mouse | 165 | symbol , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 2295069 | Gm15501 | predicted pseudogene 15501 | | 7 | 92828169 | 92833383 | Mouse | | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 2294072 | Gm14438 | predicted gene 14438 | | 2 | 175102844 | 175113039 | Mouse | | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 736082 | Adra1a | adrenergic receptor, alpha 1a | This gene encodes one of several multipass transmembrane proteins that function as G protein-coupled receptors. The encoded protein binds to epinephrine and norepinephrine to mediate signaling in cells of the cardiac, nervous, and other organ systems. Alternatively spliced transcript variants encodi ng multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012] | 14 | 66872705 | 67009549 | Mouse | 367 | GenBank Nucleotide | gene, protein-coding, REVIEWED [RefSeq] |
| 10096 | Adra1b | adrenergic receptor, alpha 1b | Enables alpha1-adrenergic receptor activity. Involved in neuron-glial cell signaling and regulation of blood pressure. Acts upstream of or within several processes, including heart development; positive regulation of blood pressure; and regulation of glycogen catabolic process. Located in membrane. Is expressed in central nervous system; heart; retina; and testis. Orthologous to human ADRA1B (adrenoceptor alpha 1B). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 43665432 | 43792076 | Mouse | 323 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 62356 | Adra1d | adrenergic receptor, alpha 1d | Enables alpha1-adrenergic receptor activity. Involved in neuron-glial cell signaling and regulation of blood pressure. Acts upstream of or within negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure and norepinephrine-e pinephrine vasoconstriction involved in regulation of systemic arterial blood pressure. Predicted to be active in plasma membrane. Is expressed in brain; diencephalon; and forebrain. Orthologous to human ADRA1D (adrenoceptor alpha 1D). [provided by Alliance of Genome Resources, Apr 2025] | 2 | 131387277 | 131404417 | Mouse | 185 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1320097 | Aga | aspartylglucosaminidase | This gene encodes an amidase enzyme that participates in the breakdown of glycoproteins in the cell. The encoded protein undergoes proteolytic processing to generate a mature enzyme. Mice lacking the encoded protein exhibit accumulation of aspartylglucosamine along with lysosomal vacuolization, axon al swelling in the gracile nucleus and impaired neuromotor coordination. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Oct 2015] | 8 | 53964718 | 53976457 | Mouse | 135 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1322470 | Alox12 | arachidonate 12-lipoxygenase | Enables arachidonate 12(S)-lipoxygenase activity and linoleate 13S-lipoxygenase activity. Involved in establishment of skin barrier; fatty acid metabolic process; and negative regulation of platelet aggregation. Located in cytoplasm. Is expressed in alimentary system; liver; liver left lobe; liver r ight lobe; and lung vascular element. Orthologous to human ALOX12 (arachidonate 12-lipoxygenase, 12S type). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 70132283 | 70146206 | Mouse | 289 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 10173 | Apoa1 | apolipoprotein A-I | This gene encodes a preproprotein that is proteolytically cleaved to yield a signal peptide and a proproptein that is subsequently processed to generate the active mature peptide. The encoded protein is the major protein component of plasma high density lipoprotein (HDL). This protein facilitates th e removal of cholesterol and other fats from tissues by transporting them to the liver for excretion. This protein is a cofactor for lecithin cholesterolacyltransferase, an enzyme that catalyzes the conversion of free cholesterol to cholesteryl esters. Mutations in this gene in humans causes familial HDL deficiency, Tangier disease and familial visceral amyloidosis. Similar clinical features are exhibited by mice with mutations in this gene. This gene is clustered with three other apolipoprotein genes on chromosome 9. [provided by RefSeq, Dec 2013] | 9 | 46139928 | 46141767 | Mouse | 743 | GenBank Nucleotide | gene, protein-coding, REVIEWED [RefSeq] |
| 10180 | Apod | apolipoprotein D | The protein encoded by this gene is a component of high-density lipoprotein (HDL), but is unique in that it shares greater structural similarity to lipocalin than to other members of the apolipoprotein family, and has a wider tissue expression pattern. The encoded protein is involved in lipid metabo lism, and ablation of this gene results in defects in triglyceride metabolism. Elevated levels of this gene product have been observed in multiple tissues of Niemann-Pick disease mouse models, as well as in some tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014] | 16 | 31115010 | 31133626 | Mouse | 254 | GenBank Nucleotide | gene, protein-coding, REVIEWED [RefSeq] |
| 737007 | Atp12a | ATPase, H+/K+ transporting, nongastric, alpha polypeptide | Predicted to enable P-type potassium:proton transporter activity and P-type sodium:potassium-exchanging transporter activity. Acts upstream of or within potassium ion homeostasis and regulation of pH. Located in basolateral plasma membrane. Is expressed in several structures, including gut; metaneph ros; pituitary gland; reproductive system; and thymus. Orthologous to human ATP12A (ATPase H+/K+ transporting non-gastric alpha2 subunit). [provided by Alliance of Genome Resources, Jul 2025] | 14 | 56602525 | 56626008 | Mouse | 120 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 10239 | Bgn | biglycan | This gene encodes a small, leucine-rich repeat proteoglycan that plays important roles in bone mineralization and connective tissue metabolism. The encoded preproprotein undergoes post-translational processing during which chondroitin sulfate or dermatan sulfate chains are attached before incorporat ion into the extracellular matrix. Mice lacking the encoded protein exhibit reduced growth rate and acquire diminished bone mass progressively with age. [provided by RefSeq, Oct 2015] | X | 72527207 | 72539542 | Mouse | 249 | GenBank Nucleotide | gene, protein-coding, REVIEWED [RefSeq] |
| 1315910 | Btn1a1 | butyrophilin, subfamily 1, member A1 | Predicted to enable signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and regulation of cytokine production. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Is expressed in central nervous system; genit ourinary system; and heart valve. Orthologous to human BTN1A1 (butyrophilin subfamily 1 member A1). [provided by Alliance of Genome Resources, Jul 2025] | 13 | 23641154 | 23650084 | Mouse | 40 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 70826 | Cdk5 | cyclin dependent kinase 5 | Enables several functions, including Hsp90 protein binding activity; acetylcholine receptor activator activity; and signaling receptor binding activity. Involved in regulation of dendritic spine morphogenesis; regulation of glutamatergic synaptic transmission; and regulation of protein localization to plasma membrane. Acts upstream of or within several processes, including chemical synaptic transmission; nervous system development; and protein phosphorylation. Located in several cellular components, including axon; filopodium; and lamellipodium. Part of protein kinase 5 complex. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and lissencephaly 7 with cerebellar hypoplasia. Orthologous to human CDK5 (cyclin dependent kinase 5). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 24612595 | 24628737 | Mouse | 444 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1553698 | Cdk5r1 | cyclin dependent kinase 5, regulatory subunit 1 | Enables several functions, including Hsp90 protein binding activity; cyclin-dependent protein serine/threonine kinase activator activity; and enzyme binding activity. Involved in several processes, including ephrin receptor signaling pathway; nervous system development; and regulation of cytoskeleto n organization. Acts upstream of or within several processes, including G1 to G0 transition involved in cell differentiation; brain development; and serine phosphorylation of STAT protein. Located in cytoplasm and nucleus. Part of protein kinase 5 complex. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study attention deficit hyperactivity disorder. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 80367849 | 80372010 | Mouse | 368 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 10322 | Cdkn2a | cyclin dependent kinase inhibitor 2A | Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; MDM2/MDM4 family protein binding activity; and enzyme inhibitor activity. Involved in several processes, including cellular response to gamma radiation; negative regulation of lymphocyte pr oliferation; and positive regulation of apoptotic process. Acts upstream of or within several processes, including keratinocyte proliferation; negative regulation of mammary gland epithelial cell proliferation; and negative regulation of protein metabolic process. Located in cytoplasm and granular component. Part of protein-containing complex. Is expressed in several structures, including central nervous system; eye; genitourinary system; immune system; and umbilical artery. Used to study high grade glioma; malignant peripheral nerve sheath tumor; melanoma (multiple); and pancreatic carcinoma (multiple). Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); carcinoma (multiple); hematologic cancer (multiple); high grade glioma (multiple); and melanoma (multiple). Orthologous to human CDKN2A (cyclin dependent kinase inhibitor 2A). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 89192710 | 89212856 | Mouse | 1223 | GenBank Protein , GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 10329 | Cebpg | CCAAT/enhancer binding protein gamma | Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in hemopoiesis; natural killer cell mediated cytotoxicity; and regulation of gene expression. Acts upstream of or within mRNA metabolic process. Located in nucleus. Is expressed in several structures, in cluding blood; central nervous system; genitourinary system; retina; and yolk sac. Orthologous to human CEBPG (CCAAT enhancer binding protein gamma). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 34745847 | 34755991 | Mouse | 194 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 731846 | Ces1e | carboxylesterase 1E | Enables carboxylesterase activity. Predicted to be involved in several processes, including cellular response to cholesterol; cholesterol homeostasis; and regulation of steroid metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Predicted to be activ e in endoplasmic reticulum and lipid droplet. Is expressed in several structures, including alimentary system; hemolymphoid system; liver; nose; and respiratory system. Human ortholog(s) of this gene implicated in colorectal cancer and gastrointestinal system cancer. Orthologous to human CES1 (carboxylesterase 1). [provided by Alliance of Genome Resources, Apr 2025] | 8 | 93927846 | 93956233 | Mouse | 100 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 10430 | Cyp11b2 | cytochrome P450, family 11, subfamily b, polypeptide 2 | Enables steroid 11-beta-monooxygenase activity. Acts upstream of or within several processes, including aldosterone biosynthetic process; drinking behavior; and regulation of systemic arterial blood pressure by hormone. Predicted to be located in dendrite and mitochondrion. Predicted to be active in mitochondrial inner membrane. Is expressed in adrenal gland and gland. Human ortholog(s) of this gene implicated in several diseases, including congenital adrenal hyperplasia; corticosterone methyloxidase deficiency 1; diabetes mellitus (multiple); hypertension (multiple); and primary hyperaldosteronism (multiple). Orthologous to several human genes including CYP11B1 (cytochrome P450 family 11 subfamily B member 1). [provided by Alliance of Genome Resources, Jul 2025] | 15 | 74722467 | 74728080 | Mouse | 302 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 68513 | Dbil5 | diazepam binding inhibitor-like 5 | Predicted to enable fatty-acyl-CoA binding activity. Predicted to be involved in fatty acid metabolic process. Predicted to be located in cytoplasm. Is expressed in testis. Orthologous to human DBIL5P (diazepam binding inhibitor-like 5, pseudogene). [provided by Alliance of Genome Resources, Jul 202 5] | 11 | 76108439 | 76109491 | Mouse | 39 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1312568 | Dlx3 | distal-less homeobox 3 | Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including cell surface receptor signaling pathway; epithelial cell differen tiation; and hair follicle cell proliferation. Acts upstream of or within blood vessel development; odontogenesis of dentin-containing tooth; and placenta development. Located in cytoplasm and nucleus. Is expressed in several structures, including brain; branchial arch; genitourinary system; jaw; and sensory organ. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 4 and trichodontoosseous syndrome. Orthologous to human DLX3 (distal-less homeobox 3). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 95010943 | 95016122 | Mouse | 147 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1320048 | Dtymk | deoxythymidylate kinase | Enables dTMP kinase activity. Acts upstream of or within cellular response to growth factor stimulus and dTDP biosynthetic process. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion and nucleus. Is expressed in several structures, including alimentary system; f orebrain; genitourinary system; midbrain; and respiratory system. Orthologous to human DTYMK (deoxythymidylate kinase). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 93720298 | 93730246 | Mouse | 173 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1317144 | Elk3 | ETS transcription factor ELK3 | Enables DNA binding activity and DNA-binding transcription factor activity. Acts upstream of or within angiogenesis; regulation of DNA-templated transcription; and wound healing. Located in nucleus. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourin ary system; and heart. Used to study congenital chylothorax. Orthologous to human ELK3 (ETS transcription factor ELK3). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 93083277 | 93147021 | Mouse | 192 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1621573 | Esrrb | estrogen related receptor, beta | Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II complex binding activity. Involved in several processes, including morula formation; photo receptor cell maintenance; and regulation of macromolecule biosynthetic process. Acts upstream of or within embryonic placenta development; trophectodermal cell proliferation; and trophectodermal cellular morphogenesis. Located in condensed chromosome; cytoplasm; and nucleus. Part of integrator complex. Is expressed in several structures, including central nervous system; early conceptus; endocrine gland; gonad; and sensory organ. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 35. Orthologous to human ESRRB (estrogen related receptor beta). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 86407891 | 86568402 | Mouse | 192 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 10579 | Fgf9 | fibroblast growth factor 9 | Predicted to enable fibroblast growth factor receptor binding activity and growth factor activity. Involved in eye development. Acts upstream of or within several processes, including positive regulation of cell population proliferation; regulation of signal transduction; and skeletal system develop ment. Predicted to be located in basement membrane. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Used to study lung cancer; multiple synostoses syndrome; and pleuropulmonary blastoma. Human ortholog(s) of this gene implicated in kidney cancer and multiple synostoses syndrome 3. Orthologous to human FGF9 (fibroblast growth factor 9). [provided by Alliance of Genome Resources, Jul 2025] | 14 | 58308543 | 58350311 | Mouse | 441 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 10594 | Fn1 | fibronectin 1 | Enables peptidase activator activity and receptor ligand activity. Involved in negative regulation of monocyte activation and response to muscle activity. Acts upstream of or within several processes, including calcium-independent cell-matrix adhesion; integrin-mediated signaling pathway; and positi ve regulation of axon extension. Located in apical plasma membrane; basement membrane; and collagen-containing extracellular matrix. Is active in extracellular space. Is expressed in several structures, including alimentary system; cardiovascular system; egg cylinder; embryo mesenchyme; and genitourinary system. Human ortholog(s) of this gene implicated in calcium oxalate nephrolithiasis; membranoproliferative glomerulonephritis; and spondylometaphyseal dysplasia corner fracture type. Orthologous to human FN1 (fibronectin 1). [provided by Alliance of Genome Resources, Apr 2025] | 1 | 71624632 | 71692439 | Mouse | 1102 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1624090 | Ftl2-ps | ferritin light polypeptide 2, pseudogene | Predicted to enable ferric iron binding activity; ferrous iron binding activity; and identical protein binding activity. Predicted to be part of ferritin complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in basal ganglia disease; hyperferritinemia-cataract syndr ome; neurodegeneration with brain iron accumulation 3; and neurodegenerative disease. Orthologous to human FTL (ferritin light chain). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 125397873 | 125398811 | Mouse | 16 | GenBank Nucleotide | gene, pseudo, INFERRED [RefSeq] |
| 735651 | Gata6 | GATA binding protein 6 | Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription coactivator binding activity. Involved in gene expression; heart contraction; and sinoatrial n ode development. Acts upstream of or within several processes, including cardiac muscle hypertrophy in response to stress; endodermal cell fate determination; and epithelial cell differentiation. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; early conceptus; embryo mesenchyme; gut; and heart. Human ortholog(s) of this gene implicated in adenocarcinoma (multiple); congenital heart disease (multiple); and pancreatic hypoplasia-diabetes-congenital heart disease syndrome. Orthologous to human GATA6 (GATA binding protein 6). [provided by Alliance of Genome Resources, Apr 2025] | 18 | 11052510 | 11085636 | Mouse | 440 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 732797 | Gdf10 | growth differentiation factor 10 | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein has been shown to promote neural repair after stroke and may act as a tumor suppressor. [provided by RefSeq, Jul 2016] | 14 | 33645544 | 33658471 | Mouse | 153 | GenBank Nucleotide | gene, protein-coding, REVIEWED [RefSeq] |
| 1621628 | Gnb4 | guanine nucleotide binding protein (G protein), beta 4 | Predicted to enable GTPase activity and signaling receptor complex adaptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in myelin sheath. Part of heterotrimeric G-protein complex. Is active in synapse. Is expressed in several structures, including clavi cle; eye; genitourinary system; heart valve; and nervous system. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate F. Orthologous to human GNB4 (G protein subunit beta 4). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 32632736 | 32670813 | Mouse | 105 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1558027 | Hmx2 | H6 homeobox 2 | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including inner ear morphogenesis; positive regulation of cell populat ion proliferation; and positive regulation of mRNA splicing, via spliceosome. Predicted to be active in nucleus. Is expressed in several structures, including genitourinary system; gut; nervous system; sensory organ; and thymus. Orthologous to human HMX2 (H6 family homeobox 2). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 131150486 | 131159743 | Mouse | 86 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1318173 | Hoxd13 | homeobox D13 | Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Acts upstream of or within several processes, including embryonic digit morphogenesis; morphogenesis of an epithelium; and regulation of branching involved in prostate gland morphogenesis. Located in nucleus. Is expressed in several structures, including genitourinary system; hindgut; limb; limb bud; and tail. Used to study synpolydactyly. Human ortholog(s) of this gene implicated in brachydactyly-syndactyly syndrome; clubfoot; cryptorchidism; and dysostosis (multiple). Orthologous to human HOXD13 (homeobox D13). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 74498569 | 74501947 | Mouse | 247 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 10775 | Igfbp4 | insulin-like growth factor binding protein 4 | Enables insulin-like growth factor binding activity. Acts upstream of or within several processes, including positive regulation of signal transduction; regulation of glucose metabolic process; and type B pancreatic cell proliferation. Located in extracellular space. Is expressed in several structur es, including alimentary system; early embryo; female reproductive system; limb; and lung. Orthologous to human IGFBP4 (insulin like growth factor binding protein 4). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 98930820 | 98943481 | Mouse | 258 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 732736 | Il13ra1 | interleukin 13 receptor, alpha 1 | This gene encodes a transmembrane protein that complexes with interleukin 4 receptor alpha (IL4RA) to form a functional receptor for interleukin-13. Signalling through this pathway mediates allergy response and occurs during bronchial asthma. [provided by RefSeq, May 2015] | X | 35375761 | 35434915 | Mouse | 217 | GenBank Nucleotide | gene, protein-coding, REVIEWED [RefSeq] |
| 732313 | Insl3 | insulin-like 3 | Predicted to enable G protein-coupled receptor binding activity and protease binding activity. Involved in regulation of male gonad development. Acts upstream of or within in utero embryonic development and male gonad development. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in extracellular space. Is expressed in Leydig cell; cornea; ovary; testis; and trunk. Used to study cryptorchidism. Human ortholog(s) of this gene implicated in cryptorchidism. Orthologous to human INSL3 (insulin like 3). [provided by Alliance of Genome Resources, Apr 2025] | 8 | 72141896 | 72143221 | Mouse | 176 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 69454 | Lcn2 | lipocalin 2 | Enables iron ion binding activity. Involved in innate immune response; positive regulation of cold-induced thermogenesis; and siderophore transport. Acts upstream of or within extrinsic apoptotic signaling pathway in absence of ligand; response to bacterium; and response to virus. Located in extrace llular space. Is expressed in several structures, including genitourinary system; gut; liver; lung; and spleen. Human ortholog(s) of this gene implicated in intrahepatic cholangiocarcinoma and urinary tract infection. Orthologous to human LCN2 (lipocalin 2). [provided by Alliance of Genome Resources, Apr 2025] | 2 | 32274649 | 32277751 | Mouse | 756 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1315271 | Lrpprc | leucine-rich PPR-motif containing | Enables RNA binding activity and single-stranded DNA binding activity. Acts upstream of or within negative regulation of mitochondrial RNA catabolic process and regulation of mitochondrial translation. Located in mitochondrion and nucleus. Part of ribonucleoprotein complex. Is expressed in several s tructures, including brain; genitourinary system; heart; liver; and skeletal muscle. Human ortholog(s) of this gene implicated in French Canadian Leigh disease and Leigh disease. Orthologous to human LRPPRC (leucine rich pentatricopeptide repeat containing). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 85012675 | 85098214 | Mouse | 196 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 731299 | Madcam1 | mucosal vascular addressin cell adhesion molecule 1 | Predicted to enable integrin binding activity involved in cell-matrix adhesion. Acts upstream of or within keratinocyte differentiation and leukocyte migration. Predicted to be located in membrane. Is expressed in eyelid; hair follicle; and hemolymphoid system. Orthologous to human MADCAM1 (mucosal vascular addressin cell adhesion molecule 1). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 79500393 | 79504376 | Mouse | 83 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1551968 | Max | Max protein | Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of DNA-templated transcription. Located in nucleus. Part of Myc-Max complex. Is expressed in several st ructures, including central nervous system; early conceptus; genitourinary system; lens; and upper jaw. Human ortholog(s) of this gene implicated in lung small cell carcinoma and pheochromocytoma. Orthologous to human MAX (MYC associated factor X). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 76984045 | 77009123 | Mouse | 200 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 10896 | Mgmt | O-6-methylguanine-DNA methyltransferase | Enables methyltransferase activity. Acts upstream of or within DNA alkylation repair. Predicted to be active in nucleoplasm. Is expressed in embryo and forelimb bud. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); endocrine gland cancer (multiple); gran ulosa cell tumor; high grade glioma (multiple); and retinoblastoma. Orthologous to human MGMT (O-6-methylguanine-DNA methyltransferase). [provided by Alliance of Genome Resources, Apr 2025] | 7 | 136496315 | 136732001 | Mouse | 426 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 10910 | Mos | Mos proto-oncogene, serine/threonine kinase | Predicted to enable MAP kinase kinase kinase activity. Involved in several processes, including microtubule cytoskeleton organization; negative regulation of metaphase/anaphase transition of meiotic cell cycle; and positive regulation of MAPK cascade. Acts upstream of or within regulation of meiotic nuclear division. Located in cytoplasm. Is expressed in brain; early conceptus; gonad; large intestine; and metanephros. Orthologous to human MOS (MOS proto-oncogene, serine/threonine kinase). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 3870658 | 3872105 | Mouse | 116 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 10914 | Mpg | N-methylpurine-DNA glycosylase | Enables alkylbase DNA N-glycosylase activity. Acts upstream of or within base-excision repair. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, including early conceptus; gonad; hemolymphoid system gland; musculature; and placenta. Orthologous to human MPG (N-m ethylpurine DNA glycosylase). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 32176505 | 32182702 | Mouse | 161 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1315100 | Mst1r | macrophage stimulating 1 receptor (c-met-related tyrosine kinase) | This gene encodes a precursor protein that is proteolytically cleaved to yield an alpha chain and a beta chain which form a membrane-spanning heterodimer. The encoded protein belongs to a family of cell-surface receptor tyrosine kinases involved in signaling from the cell surface to the intracellula r environment. The binding of the encoded protein to its ligand, macrophage-stimulating protein, mediates several biological activities including wound healing, tumor immunity, macrophage activation and hematopoiesis as well as cell growth, motility, survival and adhesion. The protein encoded by this gene also functions in early development and the macrophage-mediated inflammatory response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] | 9 | 107784057 | 107797582 | Mouse | 139 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 10933 | Myb | Myb proto-oncogene, transcription factor | Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and WD40-repeat domain binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including cellular response to cytokine stimulus; hematopoietic or lymphoid organ development; and hemopoiesis. Located in cytosol and nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and sensory organ. Used to study essential thrombocythemia and myelofibrosis. Orthologous to human MYB (MYB proto-oncogene, transcription factor). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 21000829 | 21036883 | Mouse | 285 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 10947 | Myh11 | myosin, heavy polypeptide 11, smooth muscle | Enables cytoskeletal motor activity. Acts upstream of or within smooth muscle contraction. Located in brush border; smooth muscle contractile fiber; and stress fiber. Part of muscle myosin complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; respirat ory system; and vascular system. Human ortholog(s) of this gene implicated in megacystis-microcolon-intestinal hypoperistalsis syndrome; patent ductus arteriosus; and thoracic aortic aneurysm. Orthologous to human MYH11 (myosin heavy chain 11). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 14012392 | 14109227 | Mouse | 237 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 69162 | Nfix | nuclear factor I/X | Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including learning or memory; nervous system development; and regulation of DNA-templated transcription. Acts upstream of or within several processes, including exit from mitosis; myeloid leukocyte differentiation; and nervous system development. Is active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study Scheuermann's disease and Sotos syndrome 2. Human ortholog(s) of this gene implicated in Marshall-Smith syndrome and Sotos syndrome 2. Orthologous to human NFIX (nuclear factor I X). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 85431341 | 85527086 | Mouse | 355 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 730893 | Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Enables several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; identical protein binding activity; and transcription coregulator activity. Involved in several processes, including B cell receptor signaling pathway; cellular response to virus; and regulation of gene expression. Acts upstream of or within several processes, including cellular response to tumor necrosis factor; regulation of gene expression; and response to muscle stretch. Located in cytosol. Part of NF-kappaB p50/p65 complex and transcription regulator complex. Is active in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Human ortholog(s) of this gene implicated in several diseases, including HTLV-1-associated myelopathy/tropical spastic paraparesis; carcinoma (multiple); common variable immunodeficiency 12; melanoma; and prostate cancer. Orthologous to human NFKB1 (nuclear factor kappa B subunit 1). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 135290416 | 135397422 | Mouse | 1594 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1318214 | Nkx2-2 | NK2 homeobox 2 | Enables DNA-binding transcription activator activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including endocrine pancreas development; neurogenesis; and positive regulation of cell differentiation. Lo cated in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; gut; neural ectoderm; and sensory organ. Orthologous to human NKX2-2 (NK2 homeobox 2). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 146967909 | 147037270 | Mouse | 140 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 10991 | Nos1 | nitric oxide synthase 1, neuronal | Enables nitric-oxide synthase activity. Involved in several processes, including nitric oxide biosynthetic process; positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway; and positive regulation of the force of heart contraction. Acts upstream of or within several processes, including peptidyl-cysteine S-nitrosylation; positive regulation of transcription by RNA polymerase II; and regulation of metal ion transport. Located in several cellular components, including T-tubule; Z disc; and sarcoplasmic reticulum membrane. Is active in calyx of Held. Colocalizes with caveola. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study achalasia and hypertrophic pyloric stenosis. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; asthma; and cystic fibrosis. Orthologous to human NOS1 (nitric oxide synthase 1). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 118004904 | 118096905 | Mouse | 902 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1623290 | Omt2a | oocyte maturation, alpha | Predicted to be located in cytosol. Is expressed in 2-cell stage embryo; oocyte; ovary; primary oocyte; and secondary oocyte. [provided by Alliance of Genome Resources, Jul 2025] | 9 | 78219254 | 78222079 | Mouse | 7 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1614768 | Omt2b | oocyte maturation, beta | Predicted to be located in cytosol. Is expressed in early conceptus; primary oocyte; and secondary oocyte. [provided by Alliance of Genome Resources, Jul 2025] | 9 | 78235312 | 78236902 | Mouse | 8 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 11036 | Oprd1 | opioid receptor, delta 1 | Enables G protein-coupled opioid receptor activity. Acts upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; adult locomotory behavior; and neuropeptide signaling pathway. Located in membrane. Is active in neuronal dense core vesicle. Is expressed in seve ral structures, including brain; early conceptus; genitourinary system; gut; and neural retina. Human ortholog(s) of this gene implicated in alcohol dependence; alcohol use disorder; drug dependence (multiple); opioid abuse; and withdrawal disorder. Orthologous to human OPRD1 (opioid receptor delta 1). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 131834980 | 131872042 | Mouse | 265 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 69479 | Oprk1 | opioid receptor, kappa 1 | This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and ne urotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017] | 1 | 5658673 | 5676357 | Mouse | 338 | GenBank Nucleotide | gene, protein-coding, REVIEWED [RefSeq] |
| 62380 | P2ry2 | purinergic receptor P2Y, G-protein coupled 2 | Predicted to enable A1 adenosine receptor binding activity; ATP binding activity; and G protein-coupled UTP receptor activity. Acts upstream of or within positive regulation of mucus secretion. Predicted to be located in apical plasma membrane; basolateral plasma membrane; and early endosome. Predic ted to be active in glutamatergic synapse and presynaptic active zone membrane. Is expressed in lung. Orthologous to human P2RY2 (purinergic receptor P2Y2). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 100645775 | 100661260 | Mouse | 193 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 736949 | Ppp1r1b | protein phosphatase 1, regulatory inhibitor subunit 1B | This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric dis orders in humans. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015] | 11 | 98239232 | 98248622 | Mouse | 254 | GenBank Nucleotide | gene, protein-coding, REVIEWED [RefSeq] |
| 11190 | Ptn | pleiotrophin | Predicted to enable several functions, including glycosaminoglycan binding activity; signaling receptor binding activity; and syndecan binding activity. Involved in several processes, including decidualization; learning or memory; and regulation of nervous system development. Acts upstream of or wit hin bone mineralization. Located in extracellular region. Is active in Schaffer collateral - CA1 synapse. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in adrenal carcinoma. Orthologous to human PTN (pleiotrophin). [provided by Alliance of Genome Resources, Apr 2025] | 6 | 36691863 | 36787114 | Mouse | 377 | GenBank Protein , GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 736590 | Ptpn5 | protein tyrosine phosphatase, non-receptor type 5 | Enables protein tyrosine phosphatase activity. Acts upstream of or within protein dephosphorylation. Predicted to be located in several cellular components, including perikaryon; proximal dendrite; and synaptic vesicle. Predicted to be active in cell junction; cytosol; and plasma membrane. Is expres sed in central nervous system; dorsal root ganglion; genitourinary system; retina; and submandibular gland. Orthologous to human PTPN5 (protein tyrosine phosphatase non-receptor type 5). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 46727543 | 46783774 | Mouse | 160 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1550054 | Ran | RAN, member RAS oncogene family | Predicted to enable several functions, including G protein activity; dynein intermediate chain binding activity; and guanyl ribonucleotide binding activity. Predicted to contribute to pre-miRNA binding activity. Acts upstream of or within actin cytoskeleton organization; protein import into nucleus; and protein-containing complex localization. Located in cytoplasm and nuclear envelope. Is expressed in several structures, including branchial arch; central nervous system; extraembryonic component; hemolymphoid system gland; and sensory organ. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human RAN (RAN, member RAS oncogene family). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 129097264 | 129101388 | Mouse | 344 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1318176 | Rora | RAR-related orphan receptor alpha | The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nu cleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014] | 9 | 68560627 | 69295528 | Mouse | 496 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 731039 | Soat1 | sterol O-acyltransferase 1 | Enables sterol O-acyltransferase activity. Acts upstream of or within cholesterol metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; ear; genitour inary system; heart; and viscerocranium. Human ortholog(s) of this gene implicated in Chagas disease. Orthologous to human SOAT1 (sterol O-acyltransferase 1). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 156255678 | 156301898 | Mouse | 278 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1323218 | Stat2 | signal transducer and activator of transcription 2 | Predicted to enable several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; identical protein binding activity; and ubiquitin-like protein ligase binding activity. Involved in negative regulation of type I interferon-mediated signaling pathway and type I interferon-mediated signaling pathway. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; and genitourinary system. Used to study Zika fever. Human ortholog(s) of this gene implicated in Zika fever; immunodeficiency 44; and neutropenia. Orthologous to human STAT2 (signal transducer and activator of transcription 2). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 128106367 | 128128722 | Mouse | 259 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 11437 | Tnp1 | transition protein 1 | Predicted to enable DNA binding activity. Involved in positive regulation of protein processing and sperm DNA condensation. Acts upstream of or within spermatogenesis. Located in nucleus. Part of nucleosome. Is expressed in testis. Orthologous to human TNP1 (transition protein 1). [provided by Allia nce of Genome Resources, Jul 2025] | 1 | 73054233 | 73055058 | Mouse | 102 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1557759 | Ube2l3 | ubiquitin-conjugating enzyme E2L 3 | Enables ubiquitin conjugating enzyme activity. Acts upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including brain; heart; immune system; lung; and reproductive system. Orthologous to several human genes including UBE2L3 (ubiquitin conjugating enzyme E2 L3). [provided by Alliance of Genome Resources, Apr 2025] | 16 | 16969879 | 17019363 | Mouse | 163 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 733184 | Uncx | UNC homeobox | Predicted to enable sequence-specific double-stranded DNA binding activity. Acts upstream of or within several processes, including cartilage condensation; central nervous system development; and common myeloid progenitor cell proliferation. Predicted to be located in nucleus. Is expressed in severa l structures, including central nervous system; embryo mesenchyme; genitourinary system; musculoskeletal system; and sensory organ. Orthologous to human UNCX (UNC homeobox). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 139529620 | 139533934 | Mouse | 110 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 11486 | Vipr1 | vasoactive intestinal peptide receptor 1 | Predicted to enable G protein-coupled peptide receptor activity; peptide hormone binding activity; and vasoactive intestinal polypeptide receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in brain and cerebral cortex. Human ortholog(s) of this gene implicated in achalasia. Orthologous to human VIPR1 (vasoactive intestinal peptide receptor 1). [provided by Alliance of Genome Resources, Apr 2025] | 9 | 121471782 | 121502020 | Mouse | 171 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 737317 | Vipr2 | vasoactive intestinal peptide receptor 2 | Predicted to enable G protein-coupled receptor activity and peptide hormone binding activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and negative regulation of smooth muscle cell proliferation. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; respiratory system; retina; and skeleton. Orthologous to human VIPR2 (vasoactive intestinal peptide receptor 2). [provided by Alliance of Genome Resources, Apr 2025] | 12 | 116041040 | 116117842 | Mouse | 133 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1553772 | Or51a10 | olfactory receptor family 51 subfamily A member 10 | Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors sha re a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008] | 7 | 103698615 | 103699559 | Mouse | 27 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1550591 | Or56b2 | olfactory receptor family 56 subfamily B member 2 | Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors sha re a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008] | 7 | 104337224 | 104338183 | Mouse | 24 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
