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ONTOLOGY REPORT - ANNOTATIONS

Term:myelination in peripheral nervous system
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Accession:GO:0022011 term browser browse the term
Definition:The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
Synonyms:exact_synonym: peripheral nervous system myelination


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myelination in peripheral nervous system term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam22 ADAM metallopeptidase domain 22 acts_upstream_of_or_within ISO MGI:3584137 (PMID:15876356), (PMID:20220021) RGD PMID:15876356 PMID:20220021 NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962 		JBrowse link
G Adgrg6 adhesion G protein-coupled receptor G6 involved_in ISO
IBA		 (MGI:5529749|PMID:24227709), (MGI:5629884|PMID:25695270)
GO_REF:0000033		 RGD
GO_Central		 PMID:24227709 PMID:25695270 GO_REF:0000033 MGI:5529749 MGI:5629884 NCBI chr 1:8,812,889...8,954,239
Ensembl chr 1:8,812,904...8,954,123 		JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 involved_in ISO (PMID:14508709) RGD PMID:14508709 NCBI chr16:74,647,147...74,738,784
Ensembl chr16:74,647,153...74,738,173 		JBrowse link
G Cntnap1 contactin associated protein 1 involved_in ISO
ISS		 (PMID:24319099), (PMID:27818385), (PMID:28374019)
GO_REF:0000024		 RGD
UniProt		 PMID:24319099 PMID:27818385 PMID:28374019 GO_REF:0000024 NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain acts_upstream_of_or_within ISO MGI:2153356 (PMID:24277578) RGD PMID:24277578 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597 		JBrowse link
G Dag1 dystroglycan 1 involved_in ISO (MGI:2663553|PMID:12797959) RGD PMID:12797959 MGI:2663553 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325 		JBrowse link
G Ilk integrin-linked kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3653044|MGI:4359600 (PMID:19349584)		 Ensembl
RGD		 PMID:19349584 GO_REF:0000107 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Itgb4 integrin subunit beta 4 acts_upstream_of_or_within ISO MGI:97631 (PMID:29315582) RGD PMID:29315582 NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012 		JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1856594|MGI:4359600|MGI:4439269|MGI:4441311 (PMID:1652607), (PMID:20220021), (PMID:21068328), (PMID:9671673)		 GO_Central
RGD		 PMID:1652607 PMID:9671673 PMID:20220021 PMID:21068328 GO_REF:0000033 NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874 		JBrowse link
G Myoc myocilin involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5527213|PMID:23897819)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:23897819 GO_REF:0000024 GO_REF:0000107 MGI:5527213 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127 		JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 GO_REF:0000024
(PMID:10586246)
GO_REF:0000107		 HGNC-UCL
RGD
Ensembl		 PMID:10586246 GO_REF:0000024 GO_REF:0000107 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nrg1 neuregulin 1 acts_upstream_of_or_within ISO (PMID:25453108) RGD PMID:25453108 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:97385|MGI:97631 (PMID:20553714)		 Ensembl
RGD		 PMID:20553714 GO_REF:0000107 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 acts_upstream_of_or_within ISO MGI:97384|MGI:97631 (PMID:20553714) RGD PMID:20553714 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286 		JBrowse link
G Pard3 par-3 family cell polarity regulator involved_in ISS
ISO		 GO_REF:0000024
(MGI:5295137|PMID:21949390)		 UniProt
RGD		 PMID:21949390 GO_REF:0000024 MGI:5295137 NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778 		JBrowse link
G Plec plectin involved_in ISO MGI:3721885|MGI:4414774 (PMID:19625254) RGD PMID:19625254 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467 		JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:1856217|MGI:2388488|MGI:2447704|MGI:3614822|MGI:96613|MGI:97384|MGI:97385 (PMID:12359155), (PMID:16436605), (PMID:20553714), (PMID:22337502), (PMID:25014022), (PMID:25429154), (PMID:25453108), (PMID:29315582) RGD PMID:12359155 PMID:16436605 PMID:20553714 PMID:22337502 PMID:25014022 More... NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714 		JBrowse link
G Pou3f1 POU class 3 homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:101895 (PMID:12782656)		 Ensembl
RGD		 PMID:12782656 GO_REF:0000107 NCBI chr 5:136,910,391...136,913,371
Ensembl chr 5:136,910,391...136,913,371 		JBrowse link
G Pou3f2 POU class 3 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:101896 (PMID:12782656)		 Ensembl
RGD		 PMID:12782656 GO_REF:0000107 NCBI chr 5:36,077,930...36,083,838
Ensembl chr 5:36,077,930...36,083,838 		JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha acts_upstream_of_or_within ISO MGI:3044031 (PMID:19179536) RGD PMID:19179536 NCBI chr14:91,556,743...91,606,391
Ensembl chr14:91,604,121...91,606,907 		JBrowse link
G Sh3tc2 SH3 domain and tetratricopeptide repeats 2 acts_upstream_of_or_within ISO MGI:4367025 (PMID:23553667) RGD PMID:23553667 NCBI chr18:55,416,383...55,477,419
Ensembl chr18:55,416,413...55,483,083 		JBrowse link
G Sirt2 sirtuin 2 involved_in IMP
IEA
ISO		 PMID:21949390
GO_REF:0000107
(MGI:5295137|PMID:21949390)		 Ensembl
RGD		 PMID:21949390 PMID:21949390 GO_REF:0000107 MGI:5295137, RGD:8655533 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Ski Ski proto-oncogene acts_upstream_of_or_within ISO MGI:2177555 (PMID:15312649) RGD PMID:15312649 NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733 		JBrowse link
G Slc25a46 solute carrier family 25, member 46 acts_upstream_of_or_within ISO MGI:6358090 (PMID:28934388) RGD PMID:28934388 NCBI chr18:23,215,954...23,244,917
Ensembl chr18:23,215,962...23,244,314 		JBrowse link
peripheral nervous system myelin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1 ribonuclease III involved_in ISO (MGI:4454581|PMID:20463238), (MGI:4830414|PMID:20805985) RGD PMID:20463238 PMID:20805985 MGI:4454581 MGI:4830414 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Itgb4 integrin subunit beta 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:97631 (PMID:29315582)		 Ensembl
RGD		 PMID:29315582 GO_REF:0000107 NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012 		JBrowse link
G Ncmap noncompact myelin associated protein involved_in IDA
IBA		 PMID:18650334
GO_REF:0000033		 GO_Central PMID:18650334 GO_REF:0000033, RGD:8554263 NCBI chr 5:147,608,042...147,623,266
Ensembl chr 5:147,610,677...147,618,775 		JBrowse link
G Prx periaxin involved_in ISO (MGI:1859096|PMID:10839370) RGD PMID:10839370 MGI:1859096 NCBI chr 1:82,785,082...82,807,154
Ensembl chr 1:82,786,815...82,807,407 		JBrowse link
peripheral nervous system myelin maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:20448149)		 Ensembl
RGD		 PMID:20448149 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:20448149)		 Ensembl
RGD		 PMID:20448149 GO_REF:0000107 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Fa2h fatty acid 2-hydroxylase acts_upstream_of_or_within ISO MGI:3829000 (PMID:18815260) RGD PMID:18815260 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 involved_in ISO
IEA		 (MGI:3041895|PMID:15082788)
GO_REF:0000107		 RGD
Ensembl		 PMID:15082788 GO_REF:0000107 MGI:3041895 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Pals1 protein associated with LIN7 1, MAGUK p55 family member involved_in ISO (MGI:4441217|PMID:20237282) RGD PMID:20237282 MGI:4441217 NCBI chr 6:97,548,133...97,654,163
Ensembl chr 6:97,548,630...97,653,305 		JBrowse link
G Plec plectin involved_in IEA
ISO		 GO_REF:0000107
MGI:3721885 (PMID:23836526)		 Ensembl
RGD		 PMID:23836526 GO_REF:0000107 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467 		JBrowse link
G Prx periaxin involved_in ISO
IBA		 (MGI:1859096|PMID:10839370)
GO_REF:0000033		 RGD
GO_Central		 PMID:10839370 GO_REF:0000033 MGI:1859096 NCBI chr 1:82,785,082...82,807,154
Ensembl chr 1:82,786,815...82,807,407 		JBrowse link
G Sh3tc2 SH3 domain and tetratricopeptide repeats 2 acts_upstream_of_or_within ISO MGI:4367025 (PMID:19805030) RGD PMID:19805030 NCBI chr18:55,416,383...55,477,419
Ensembl chr18:55,416,413...55,483,083 		JBrowse link
G Sod1 superoxide dismutase 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1857872 (PMID:10433959)		 UniProt
RGD		 PMID:10433959 GO_REF:0000024 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    cellular process 18196
      ensheathment of neurons 197
        axon ensheathment 197
          myelination 195
            myelination in peripheral nervous system 33
              peripheral nervous system myelin formation 4
              peripheral nervous system myelin maintenance 9
Path 2
Term Annotations click to browse term
  biological_process 19692
    developmental process 6963
      anatomical structure development 6486
        multicellular organism development 5239
          system development 4526
            nervous system development 2801
              neurogenesis 2065
                gliogenesis 441
                  glial cell differentiation 325
                    glial cell development 155
                      Schwann cell development 48
                        myelination in peripheral nervous system 33
                          peripheral nervous system myelin formation 4
                          peripheral nervous system myelin maintenance 9
paths to the root