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ONTOLOGY REPORT - ANNOTATIONS

Term:dendritic spine maintenance
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Accession:GO:0097062 term browser browse the term
Definition:The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.


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dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:99695 (PMID:23365224) RGD PMID:23365224 NCBI chr13:68,673,702...68,770,846
Ensembl chr13:68,673,722...68,839,742 		JBrowse link
G Ckap5 cytoskeleton associated protein 5 acts_upstream_of_or_within ISO MGI:2177650|MGI:5570192 (PMID:23936366) RGD PMID:23936366 NCBI chr 3:77,491,195...77,593,300
Ensembl chr 3:77,491,276...77,593,264 		JBrowse link
G Cntnap2 contactin associated protein 2 involved_in ISO MGI:2677631 (PMID:31141683) RGD PMID:31141683 NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027 		JBrowse link
G Cttn cortactin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:87860 (PMID:23365224)		 Ensembl
RGD		 PMID:23365224 GO_REF:0000107 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor involved_in IGI PMID:19406747 ARUK-UCL PMID:19406747 RGD:13210538 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Insr insulin receptor involved_in IGI PMID:19406747 ARUK-UCL PMID:19406747 RGD:13210538 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Itga3 integrin subunit alpha 3 acts_upstream_of_or_within ISO MGI:1857792|MGI:87860 (PMID:23595732) RGD PMID:23595732 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118 		JBrowse link
G Itpka inositol-trisphosphate 3-kinase A acts_upstream_of_or_within IMP PMID:19890013 MGI PMID:19890013 RGD:8553536 NCBI chr 3:106,726,036...106,734,601
Ensembl chr 3:106,726,036...106,734,600 		JBrowse link
G Mtmr2 myotubularin related protein 2 involved_in IMP PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chr 8:10,617,993...10,670,724
Ensembl chr 8:10,617,993...10,668,172 		JBrowse link
G Pick1 protein interacting with PRKCA 1 involved_in IMP
IBA		 PMID:18297063
GO_REF:0000033		 GO_Central PMID:18297063 GO_REF:0000033, RGD:8554748 NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848 		JBrowse link
G Tanc1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4125076 (PMID:21068316)		 Ensembl
RGD		 PMID:21068316 GO_REF:0000107 NCBI chr 3:44,099,387...44,335,478
Ensembl chr 3:44,134,016...44,331,627 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6393391|PMID:31980586) RGD PMID:31980586 MGI:6393391 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
negative regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E acts_upstream_of_or_within ISO (PMID:24328732) RGD PMID:24328732 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Cfl1 cofilin 1 involved_in IMP
NAS		 PMID:17360908 RGD
ARUK-UCL		 PMID:23974706 PMID:17360908 RGD:11570553, RGD:12793018 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in ISO
IEA		 UniProtKB:P04925|UniProtKB:Q01097 (MGI:5447900|PMID:22820466)
GO_REF:0000107		 RGD
Ensembl		 PMID:22820466 GO_REF:0000107 MGI:5447900 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B involved_in ISO UniProtKB:P04925|UniProtKB:P39688 (MGI:5447900|PMID:22820466) RGD PMID:22820466 MGI:5447900 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Prnp prion protein involved_in ISO ComplexPortal:CPX-1134|UniProtKB:P39688|UniProtKB:Q01097 (MGI:5447900|PMID:22820466), (MGI:5515653|PMID:24012003) RGD PMID:22820466 PMID:24012003 MGI:5447900 MGI:5515653 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
positive regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:24328732)		 Ensembl
RGD		 PMID:24328732 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 IMP RGD PMID:30206770 RGD:405650589 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 involved_in IGI PMID:17360908 ARUK-UCL PMID:17360908 RGD:12793018 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Ins2 insulin 2 involved_in ISO ComplexPortal:CPX-1134 (PMID:19188609) RGD PMID:19188609 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 involved_in ISO (MGI:5752429|PMID:26683084) RGD PMID:26683084 MGI:5752429 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019 		JBrowse link
G Zfp804a zinc finger protein 804A involved_in IMP PMID:27837918 UniProt PMID:27837918 RGD:13210564 NCBI chr 3:67,033,481...67,267,769
Ensembl chr 3:67,034,170...67,263,607 		JBrowse link
G Zmynd8 zinc finger, MYND-type containing 8 IMP RGD PMID:24117785 RGD:8554267 NCBI chr 3:154,528,917...154,629,532
Ensembl chr 3:154,529,043...154,628,463 		JBrowse link
regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd17b abhydrolase domain containing 17B, depalmitoylase involved_in ISO
IEA		 (MGI:6094388|PMID:27307232)
GO_REF:0000107		 RGD
Ensembl		 PMID:27307232 GO_REF:0000107 MGI:6094388 NCBI chr 1:219,198,294...219,232,733
Ensembl chr 1:219,198,471...219,231,933 		JBrowse link
G App amyloid beta precursor protein involved_in ISO ComplexPortal:CPX-1134 (PMID:23921129) RGD PMID:23921129 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Fcgr2b Fc gamma receptor 2B involved_in ISO UniProtKB:P05067-PRO_0000000092 (PMID:23921129)
(MGI:5514474|PMID:23921129)		 RGD PMID:23921129 MGI:5514474 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Homer1 homer scaffold protein 1 involved_in IMP
ISS		 PMID:19345194
GO_REF:0000024		 UniProt PMID:19345194 GO_REF:0000024, RGD:8553291 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785 		JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (PMID:26618722) RGD PMID:26618722 NCBI chr19:21,765,771...21,801,620
Ensembl chr19:21,765,749...21,801,618 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    cellular process 18168
      cellular component organization or biogenesis 6958
        cellular component organization 6699
          cellular component maintenance 111
            dendritic spine maintenance 28
              negative regulation of dendritic spine maintenance 5
              positive regulation of dendritic spine maintenance 7
              regulation of dendritic spine maintenance + 16
Path 2
Term Annotations click to browse term
  biological_process 19692
    cellular process 18168
      cellular component organization or biogenesis 6958
        cellular component organization 6699
          cell junction organization 970
            synapse organization 694
              postsynapse organization 334
                dendritic spine organization 106
                  dendritic spine maintenance 28
                    negative regulation of dendritic spine maintenance 5
                    positive regulation of dendritic spine maintenance 7
                    regulation of dendritic spine maintenance + 16
paths to the root