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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of peptidyl-tyrosine phosphorylation
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Accession:GO:0050732 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
Synonyms:exact_synonym: down regulation of peptidyl-tyrosine phosphorylation;   downregulation of peptidyl-tyrosine phosphorylation
 narrow_synonym: inhibition of peptidyl-tyrosine phosphorylation



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negative regulation of peptidyl-tyrosine phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadm4 cell adhesion molecule 4 involved_in ISS
ISO
GO_REF:0000024
(PMID:23611113)
UniProt
RGD
PMID:23611113 GO_REF:0000024 NCBI chr 1:80,075,163...80,097,423
Ensembl chr 1:80,075,202...80,097,423
JBrowse link
G Dmtn dematin actin binding protein involved_in ISO (PMID:18505823) RGD PMID:18505823 NCBI chr15:45,677,974...45,702,261
Ensembl chr15:45,677,977...45,705,601
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 involved_in IDA PMID:17599051 UniProt PMID:17599051 RGD:8553726 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO MGI:2386329 (PMID:21677284) RGD PMID:21677284 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il18 interleukin 18 IMP RGD PMID:22001439 RGD:8655996 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Lrrk1 leucine-rich repeat kinase 1 acts_upstream_of_or_within ISO MGI:5568128 (PMID:23526378) RGD PMID:23526378 NCBI chr 1:119,844,360...119,972,885
Ensembl chr 1:119,845,146...119,979,734
JBrowse link
G Mir106b microRNA 106b involved_in ISO (PMID:27520374) RGD PMID:27520374 NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425
JBrowse link
G Ntf3 neurotrophin 3 involved_in ISO (PMID:23027130) RGD PMID:23027130 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IDA RGD PMID:17662049 RGD:7240703 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Prkcd protein kinase C, delta involved_in ISO (PMID:14583092) RGD PMID:14583092 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkcz protein kinase C, zeta involved_in ISO (PMID:15069075) RGD PMID:15069075 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 IMP RGD PMID:12117721 RGD:401965428 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in
acts_upstream_of_or_within
ISO (PMID:19749791)
MGI:1856074 (PMID:9254656)
RGD PMID:9254656 PMID:19749791 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO (PMID:7499277), (PMID:8175795) RGD PMID:7499277 PMID:8175795 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 involved_in ISO (PMID:19923443) RGD PMID:19923443 NCBI chr11:14,484,523...14,534,900
Ensembl chr11:14,483,893...14,534,900
JBrowse link
G Sema4d semaphorin 4D involved_in ISO (PMID:22019888) RGD PMID:22019888 NCBI chr17:13,430,324...13,537,146
Ensembl chr17:13,430,379...13,537,138
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO (PMID:10980594) RGD PMID:10980594 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO (PMID:10980594) RGD PMID:10980594 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 acts_upstream_of_or_within ISO (PMID:22228629) RGD PMID:22228629 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cblc Cbl proto-oncogene C involved_in ISO (PMID:10362357) RGD PMID:10362357 NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755
JBrowse link
G Chmp6 charged multivesicular body protein 6 involved_in ISO (PMID:16973552) RGD PMID:16973552 NCBI chr10:105,191,972...105,197,642
Ensembl chr10:105,191,950...105,197,640
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 involved_in IDA
ISO
ISS
PMID:17599051
(PMID:16648858)
(PMID:18046415)
GO_REF:0000024
RGD
UniProt
PMID:16648858 PMID:18046415 PMID:17599051 GO_REF:0000024, RGD:8553726 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A involved_in ISO (PMID:25744720) RGD PMID:25744720 NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260
JBrowse link
G Psen1 presenilin 1 involved_in ISO (PMID:20208556) RGD PMID:20208556 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Psen2 presenilin 2 involved_in ISO (PMID:20208556) RGD PMID:20208556 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Socs4 suppressor of cytokine signaling 4 involved_in ISO (PMID:15590694) RGD PMID:15590694 NCBI chr15:20,523,406...20,537,889
Ensembl chr15:20,523,183...20,542,494
JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (PMID:15590694) RGD PMID:15590694 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834
JBrowse link
G Tsg101 tumor susceptibility 101 involved_in ISO (PMID:16973552) RGD PMID:16973552 NCBI chr 1:97,412,689...97,442,589
Ensembl chr 1:97,410,848...97,442,554
JBrowse link
G Vps25 vacuolar protein sorting 25 homolog involved_in ISO (PMID:16973552) RGD PMID:16973552 NCBI chr10:86,196,062...86,201,606
Ensembl chr10:86,188,812...86,231,829
JBrowse link
G Zfyve28 zinc finger FYVE-type containing 28 involved_in ISO (PMID:19460345) RGD PMID:19460345 NCBI chr14:76,468,424...76,554,039
Ensembl chr14:76,468,424...76,554,039
JBrowse link
G Zgpat zinc finger CCCH-type and G-patch domain containing involved_in ISS
ISO
GO_REF:0000024
(PMID:19644445)
UniProt
RGD
PMID:19644445 GO_REF:0000024 NCBI chr 3:168,473,836...168,490,380
Ensembl chr 3:168,473,981...168,490,380
JBrowse link
negative regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf4a hepatocyte nuclear factor 4, alpha IDA RGD PMID:16584384 RGD:1625011 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
negative regulation of protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ggnbp2 gametogenetin binding protein 2 acts_upstream_of_or_within ISO MGI:4072637 (PMID:26764350) RGD PMID:26764350 NCBI chr10:69,711,527...69,743,134
Ensembl chr10:69,711,532...69,743,365
JBrowse link
G Hyal2 hyaluronidase 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:12676986)
UniProt
RGD
PMID:12676986 GO_REF:0000024 NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:16493035), (PMID:9151699) RGD PMID:9151699 PMID:16493035 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
JBrowse link
G Mvp major vault protein involved_in ISO (PMID:16441665) RGD PMID:16441665 NCBI chr 1:181,594,734...181,622,336
Ensembl chr 1:181,594,734...181,622,380
JBrowse link
G Ptk6 protein tyrosine kinase 6 involved_in ISO (PMID:15539407) RGD PMID:15539407 NCBI chr 3:168,307,073...168,315,664
Ensembl chr 3:168,307,073...168,315,664
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO (PMID:21216966) RGD PMID:21216966 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627
JBrowse link
G Srcin1 SRC kinase signaling inhibitor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:17525734)
UniProt
RGD
PMID:17525734 GO_REF:0000024 NCBI chr10:82,502,911...82,569,882
Ensembl chr10:82,504,393...82,571,040
JBrowse link
negative regulation of tyrosine phosphorylation of STAT protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 acts_upstream_of_or_within ISO MGI:2180364 (PMID:12388746) RGD PMID:12388746 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Ggnbp2 gametogenetin binding protein 2 acts_upstream_of_or_within ISO MGI:4072637 (PMID:26764350) RGD PMID:26764350 NCBI chr10:69,711,527...69,743,134
Ensembl chr10:69,711,532...69,743,365
JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F involved_in ISO (PMID:25476455) RGD PMID:25476455 NCBI chr 1:183,190,480...183,270,276
Ensembl chr 1:183,190,480...183,270,276
JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 involved_in ISO (PMID:27796300) RGD PMID:27796300 NCBI chr11:64,902,848...64,934,916
Ensembl chr11:64,902,785...64,934,916
JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:16393965) RGD PMID:16393965 NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:12359225)
UniProt
RGD
PMID:12359225 GO_REF:0000024 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627
JBrowse link
G Socs1 suppressor of cytokine signaling 1 acts_upstream_of_or_within ISO (PMID:9202127) RGD PMID:9202127 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        phosphorus metabolic process 2406
          phosphate-containing compound metabolic process 2403
            phosphorylation 1348
              protein phosphorylation 1254
                negative regulation of protein phosphorylation 310
                  negative regulation of peptidyl-tyrosine phosphorylation 43
                    negative regulation of peptidyl-tyrosine autophosphorylation 0
                    negative regulation of protein tyrosine kinase activity + 20
                    negative regulation of tyrosine phosphorylation of STAT protein 7
Path 2
Term Annotations click to browse term
  biological_process 20076
    biological regulation 13559
      regulation of biological process 13136
        regulation of cellular process 12773
          regulation of metabolic process 6747
            regulation of macromolecule metabolic process 6220
              regulation of protein metabolic process 2178
                regulation of protein modification process 1194
                  regulation of protein phosphorylation 919
                    negative regulation of protein phosphorylation 310
                      negative regulation of peptidyl-tyrosine phosphorylation 43
                        negative regulation of peptidyl-tyrosine autophosphorylation 0
                        negative regulation of protein tyrosine kinase activity + 20
                        negative regulation of tyrosine phosphorylation of STAT protein 7
paths to the root