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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of mitotic nuclear division
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Accession:GO:0045839 term browser browse the term
Definition:Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.
Synonyms:exact_synonym: down regulation of mitosis;   downregulation of mitosis;   negative regulation of mitosis
 narrow_synonym: inhibition of mitosis


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negative regulation of mitotic nuclear division term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114 		JBrowse link
G Chek1 checkpoint kinase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:36,619,935...36,637,897
Ensembl chr 9:36,619,778...36,638,361 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) involved_in NAS (MGI:3691915|PMID:12119130) UniProt PMID:12119130 MGI:3691915 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within IGI (PMID:18455718) MGI PMID:18455718 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within IGI (PMID:18455718) MGI PMID:18455718 NCBI chr 5:33,879,068...33,894,412
Ensembl chr 5:33,879,018...33,894,412 		JBrowse link
G Mtbp Mdm2, transformed 3T3 cell double minute p53 binding protein acts_upstream_of_or_within IDA (PMID:21274008) MGI PMID:21274008 NCBI chr15:55,420,800...55,489,819
Ensembl chr15:55,420,804...55,489,819 		JBrowse link
G Nme6 NME/NM23 nucleoside diphosphate kinase 6 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:109,661,830...109,672,042
Ensembl chr 9:109,661,817...109,672,184 		JBrowse link
G Tom1l1 target of myb1-like 1 (chicken) involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:90,536,516...90,579,105
Ensembl chr11:90,534,291...90,579,192 		JBrowse link
G Tom1l2 target of myb1-like 2 (chicken) involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:60,114,622...60,243,766
Ensembl chr11:60,117,540...60,243,731 		JBrowse link
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mad1l1 MAD1 mitotic arrest deficient 1-like 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:139,994,444...140,307,346
Ensembl chr 5:139,994,444...140,307,307 		JBrowse link
G Mad2l1bp MAD2L1 binding protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:46,458,311...46,464,477
Ensembl chr17:46,458,313...46,464,479 		JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:139,673,309...139,677,116
Ensembl chr 7:139,673,308...139,677,113 		JBrowse link
mitotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC, WNT signaling pathway regulator acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605 		JBrowse link
G Arhgap33os Rho GTPase activating protein 33, opposite strand involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:30,214,547...30,221,618
Ensembl chr 7:30,214,547...30,221,618 		JBrowse link
G Atm ataxia telangiectasia mutated involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569 		JBrowse link
G Bub1 BUB1, mitotic checkpoint serine/threonine kinase involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 2:127,642,117...127,673,790
Ensembl chr 2:127,643,036...127,673,785 		JBrowse link
G Bub1b BUB1B, mitotic checkpoint serine/threonine kinase involved_in NAS
IBA
ISO		 (MGI:6870992|PMID:11535616) ComplexPortal
GO_Central
MGI		 PMID:11535616 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:6870992 NCBI chr 2:118,428,684...118,472,073
Ensembl chr 2:118,428,692...118,472,072 		JBrowse link
G Bub3 BUB3 mitotic checkpoint protein involved_in NAS
IBA		 (MGI:6870992|PMID:11535616) ComplexPortal
GO_Central		 PMID:11535616 GO_REF:0000033 MGI:6870992 NCBI chr 7:131,162,081...131,173,625
Ensembl chr 7:131,161,951...131,173,624 		JBrowse link
G Cdc20 cell division cycle 20 involved_in NAS (MGI:6870992|PMID:11535616) ComplexPortal PMID:11535616 MGI:6870992 NCBI chr 4:118,290,098...118,294,540
Ensembl chr 4:118,290,098...118,294,549 		JBrowse link
G Cenpe centromere protein E involved_in IMP (MGI:2673075|PMID:12925705) UniProt PMID:12925705 MGI:2673075 NCBI chr 3:134,918,324...134,979,301
Ensembl chr 3:134,918,298...134,979,372 		JBrowse link
G Cep192 centrosomal protein 192 acts_upstream_of_or_within ISO (PMID:18207742) MGI PMID:18207742 NCBI chr18:67,933,124...68,018,241
Ensembl chr18:67,933,177...68,018,241 		JBrowse link
G Haspin histone H3 associated protein kinase involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:73,026,310...73,029,120
Ensembl chr11:73,026,311...73,029,120 		JBrowse link
G Ik IK cytokine involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:36,877,709...36,890,692
Ensembl chr18:36,877,731...36,890,688 		JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member acts_upstream_of_or_within IMP (PMID:19376971) MGI PMID:19376971 NCBI chr 9:73,008,660...73,013,915
Ensembl chr 9:73,009,118...73,011,720 		JBrowse link
G Klhl22 kelch-like 22 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:17,577,485...17,611,246
Ensembl chr16:17,577,482...17,611,246 		JBrowse link
G Kntc1 kinetochore associated 1 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 5:123,887,755...123,959,656
Ensembl chr 5:123,887,779...123,959,656 		JBrowse link
G Mad1l1 MAD1 mitotic arrest deficient 1-like 1 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 5:139,994,444...140,307,346
Ensembl chr 5:139,994,444...140,307,307 		JBrowse link
G Mad2l1 MAD2 mitotic arrest deficient-like 1 involved_in
acts_upstream_of_or_within		 NAS
IBA
ISA
IMP
ISO		 (MGI:6870992|PMID:11535616)
(PMID:10892650)
(PMID:11201745)		 ComplexPortal
GO_Central
MGI		 PMID:10892650 PMID:11201745 PMID:11535616 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:6870992 NCBI chr 6:66,512,205...66,518,091
Ensembl chr 6:66,512,374...66,524,204 		JBrowse link
G Mad2l1bp MAD2L1 binding protein acts_upstream_of_or_within ISO (PMID:12456649), (PMID:14568551) MGI PMID:12456649 PMID:14568551 NCBI chr17:46,458,311...46,464,477
Ensembl chr17:46,458,313...46,464,479 		JBrowse link
G Ndc80 NDC80 kinetochore complex component involved_in NAS (MGI:6869996|PMID:18455984) ComplexPortal PMID:18455984 MGI:6869996 NCBI chr17:71,803,095...71,833,852
Ensembl chr17:71,803,095...71,833,852 		JBrowse link
G Nuf2 NUF2, NDC80 kinetochore complex component involved_in NAS (MGI:6869996|PMID:18455984) ComplexPortal PMID:18455984 MGI:6869996 NCBI chr 1:169,325,503...169,359,033
Ensembl chr 1:169,325,503...169,359,033 		JBrowse link
G Plk1 polo like kinase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:121,758,658...121,769,107
Ensembl chr 7:121,758,662...121,769,096 		JBrowse link
G Psmg2 proteasome (prosome, macropain) assembly chaperone 2 acts_upstream_of_or_within IDA (PMID:12147697) MGI PMID:12147697 NCBI chr18:67,774,657...67,787,251
Ensembl chr18:67,774,669...67,787,232 		JBrowse link
G Spc24 SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) involved_in NAS (MGI:6869996|PMID:18455984) ComplexPortal PMID:18455984 MGI:6869996 NCBI chr 9:21,666,730...21,671,741
Ensembl chr 9:21,666,738...21,671,599 		JBrowse link
G Spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) involved_in NAS (MGI:6869996|PMID:18455984) ComplexPortal PMID:18455984 MGI:6869996 NCBI chr 2:69,009,753...69,036,583
Ensembl chr 2:69,024,239...69,036,538 		JBrowse link
G Spdl1 spindle apparatus coiled-coil protein 1 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr11:34,700,012...34,724,492
Ensembl chr11:34,700,017...34,724,468 		JBrowse link
G Tex14 testis expressed gene 14 intercellular bridge forming factor involved_in IMP
IBA		 (MGI:5318128|PMID:22405274) UniProt
GO_Central		 PMID:22405274 GO_REF:0000033 MGI:5318128 NCBI chr11:87,295,839...87,446,649
Ensembl chr11:87,295,891...87,446,649 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:150,268,544...150,325,686
Ensembl chr 1:150,268,589...150,325,686 		JBrowse link
G Trip13 thyroid hormone receptor interactor 13 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:74,060,577...74,085,855
Ensembl chr13:74,059,466...74,085,903 		JBrowse link
G Ttk Ttk protein kinase involved_in IBA
IMP		 (PMID:25197064) GO_Central
MGI		 PMID:25197064 GO_REF:0000033 NCBI chr 9:83,716,704...83,754,442
Ensembl chr 9:83,716,742...83,754,442 		JBrowse link
G Zfp207 zinc finger protein 207 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr11:80,274,105...80,299,387
Ensembl chr11:80,274,105...80,296,559 		JBrowse link
G Zw10 zw10 kinetochore protein involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:48,966,880...48,990,075
Ensembl chr 9:48,966,913...48,990,075 		JBrowse link
G Zwilch zwilch kinetochore protein involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:64,044,426...64,080,210
Ensembl chr 9:64,044,426...64,080,386 		JBrowse link
G Zwint ZW10 interactor involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr10:72,490,678...72,510,796
Ensembl chr10:72,490,677...72,510,796 		JBrowse link
negative regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:5,749,155...5,755,465
Ensembl chr10:5,749,160...5,755,600 		JBrowse link
G Mad2l1 MAD2 mitotic arrest deficient-like 1 acts_upstream_of_or_within TAS (PMID:12147697) MGI PMID:12147697 NCBI chr 6:66,512,205...66,518,091
Ensembl chr 6:66,512,374...66,524,204 		JBrowse link
G Rad21 RAD21 cohesin complex component involved_in IMP (MGI:1340883|PMID:10375619) CAFA PMID:10375619 MGI:1340883 NCBI chr15:51,826,000...51,856,934
Ensembl chr15:51,825,636...51,855,143 		JBrowse link
G Usp44 ubiquitin specific peptidase 44 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:93,655,831...93,696,792
Ensembl chr10:93,667,417...93,693,950 		JBrowse link
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in NAS (MGI:6867145|PMID:17956729) ComplexPortal PMID:17956729 MGI:6867145 NCBI chr11:68,936,477...68,942,490
Ensembl chr11:68,936,473...68,942,490 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 involved_in NAS (MGI:6867145|PMID:17956729) ComplexPortal PMID:17956729 MGI:6867145 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569 		JBrowse link
G Cdca8 cell division cycle associated 8 involved_in NAS (MGI:6867145|PMID:17956729) ComplexPortal PMID:17956729 MGI:6867145 NCBI chr 4:124,812,258...124,830,710
Ensembl chr 4:124,812,258...124,833,104 		JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:114,517,899...114,552,856
Ensembl chr 9:114,517,858...114,553,370 		JBrowse link
G Gen1 GEN1, Holliday junction 5' flap endonuclease involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr12:11,288,929...11,316,030
Ensembl chr12:11,288,921...11,315,802 		JBrowse link
G Incenp inner centromere protein involved_in NAS (MGI:6867145|PMID:17956729) ComplexPortal PMID:17956729 MGI:6867145 NCBI chr19:9,849,659...9,876,853
Ensembl chr19:9,849,660...9,876,915 		JBrowse link
G Mad1l1 MAD1 mitotic arrest deficient 1-like 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:139,994,444...140,307,346
Ensembl chr 5:139,994,444...140,307,307 		JBrowse link
G Mad2l1 MAD2 mitotic arrest deficient-like 1 involved_in IMP
ISO		 (MGI:4839685|PMID:20870947) UniProt
MGI		 PMID:20870947 GO_REF:0000119 MGI:4834177 MGI:4839685 NCBI chr 6:66,512,205...66,518,091
Ensembl chr 6:66,512,374...66,524,204 		JBrowse link
G Ndc80 NDC80 kinetochore complex component involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:71,803,095...71,833,852
Ensembl chr17:71,803,095...71,833,852 		JBrowse link
G Pcid2 PCI domain containing 2 involved_in IMP
ISO		 (MGI:4839685|PMID:20870947) UniProt
MGI		 PMID:20870947 GO_REF:0000119 MGI:4834177 MGI:4839685 NCBI chr 8:13,125,476...13,155,343
Ensembl chr 8:13,127,189...13,155,459 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:150,268,544...150,325,686
Ensembl chr 1:150,268,589...150,325,686 		JBrowse link
G Xrcc3 X-ray repair complementing defective repair in Chinese hamster cells 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr12:111,769,626...111,780,326
Ensembl chr12:111,769,626...111,780,307 		JBrowse link
regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc15 anaphase promoting complex C subunit 15 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 7:101,530,508...101,551,056
Ensembl chr 7:101,512,922...101,551,056 		JBrowse link
G Anapc15-ps anaphase promoting complex C subunit 15, pseudogene involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr10:95,508,550...95,509,377
Ensembl chr10:95,508,853...95,509,251 		JBrowse link
G Ccnb1 cyclin B1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078 		JBrowse link
G Ccnb1-ps cyclin B1, pseudogene involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:41,755,193...41,756,726
Ensembl chr 7:41,755,323...41,756,609 		JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 4:70,135,092...70,328,672
Ensembl chr 4:70,135,093...70,328,680 		JBrowse link
G Knl1 kinetochore scaffold 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:118,877,600...118,940,978
Ensembl chr 2:118,877,600...118,935,982 		JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr 7:122,977,026...123,029,581
Ensembl chr 7:122,969,007...123,029,581 		JBrowse link
G Prpf4b pre-mRNA processing factor 4B involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:35,058,803...35,090,047
Ensembl chr13:35,059,285...35,090,047 		JBrowse link
G Usp44 ubiquitin specific peptidase 44 involved_in IDA (MGI:5448515|PMID:21853124) UniProt PMID:21853124 MGI:5448515 NCBI chr10:93,655,831...93,696,792
Ensembl chr10:93,667,417...93,693,950 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28577
    cellular process 17497
      cell cycle process 1354
        negative regulation of cell cycle process 345
          negative regulation of mitotic nuclear division 62
            negative regulation of mitotic metaphase/anaphase transition + 52
Path 2
Term Annotations click to browse term
  biological_process 28577
    cellular process 17497
      cellular component organization or biogenesis 6979
        cellular component organization 6766
          organelle organization 3726
            organelle fission 526
              nuclear division 468
                mitotic nuclear division 281
                  regulation of mitotic nuclear division 122
                    negative regulation of mitotic nuclear division 62
                      negative regulation of mitotic metaphase/anaphase transition + 52
paths to the root