Ttk (Ttk protein kinase) - Rat Genome Database

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Gene: Ttk (Ttk protein kinase) Mus musculus
Analyze
Symbol: Ttk
Name: Ttk protein kinase
RGD ID: 1313656
MGI Page MGI
Description: Enables identical protein binding activity; kinetochore binding activity; and protein serine/threonine/tyrosine kinase activity. Involved in mitotic spindle assembly checkpoint signaling. Acts upstream of or within several processes, including meiotic spindle assembly checkpoint signaling; protein localization to organelle; and protein phosphorylation. Predicted to be located in cytoplasm and membrane. Predicted to be active in kinetochore; nucleus; and spindle. Is expressed in brain; lung; metanephros; and ureteric tip. Orthologous to human TTK (TTK protein kinase); PARTICIPATES IN cell cycle pathway, mitotic; INTERACTS WITH 1,1-dichloroethene; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AL022661; dual specificity protein kinase TTK; esk; Esk1; Mp; Mps1; PYT
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39983,716,704 - 83,754,443 (+)NCBIGRCm39mm39
GRCm39 Ensembl983,716,742 - 83,754,442 (+)Ensembl
GRCm38983,834,651 - 83,872,390 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl983,834,689 - 83,872,389 (+)EnsemblGRCm38mm10GRCm38
MGSCv37983,728,296 - 83,765,997 (+)NCBIGRCm37mm9NCBIm37
MGSCv36983,631,459 - 83,669,102 (+)NCBImm8
Celera980,934,680 - 80,972,688 (+)NCBICelera
Cytogenetic Map9E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (EXP)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3-methylcholanthrene  (EXP)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (EXP)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
aristolochic acid  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bisphenol A  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
cefaloridine  (ISO)
choline  (EXP)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cryptolepine  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
deguelin  (ISO)
deoxynivalenol  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (EXP)
dicrotophos  (ISO)
dieldrin  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
etoposide  (ISO)
folic acid  (EXP)
fulvestrant  (ISO)
furan  (ISO)
genistein  (ISO)
geraniol  (ISO)
GW 4064  (ISO)
irinotecan  (ISO)
kojic acid  (ISO)
L-methionine  (EXP)
leflunomide  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
lucanthone  (ISO)
methamphetamine  (ISO)
methylseleninic acid  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N-nitrosourea  (EXP)
N-nitrosodiethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
PCB138  (EXP)
perfluorononanoic acid  (ISO)
phenformin  (ISO)
phenobarbital  (EXP)
PhIP  (ISO)
phytoestrogen  (ISO)
picoxystrobin  (ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
propanal  (ISO)
pyrimidifen  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
SCH 23390  (ISO)
senecionine  (ISO)
Senkirkine  (ISO)
silicon dioxide  (EXP)
sirolimus  (ISO)
sodium arsenite  (EXP,ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thalidomide  (ISO)
thapsigargin  (ISO)
thifluzamide  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
triptonide  (EXP)
troglitazone  (ISO)
valproic acid  (ISO)
vincaleukoblastine  (ISO)
vinclozolin  (ISO)
zoledronic acid  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1375325   PMID:7671812   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11389549   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273  
PMID:16141072   PMID:16141073   PMID:16183747   PMID:17015433   PMID:18799693   PMID:18827223   PMID:20360068   PMID:21267068   PMID:21402910   PMID:21558374   PMID:21873635   PMID:22645261  
PMID:25197064   PMID:25897860   PMID:26496610   PMID:26953350   PMID:27631493   PMID:28705898   PMID:28947820   PMID:32198375   PMID:33420244   PMID:34031364  


Genomics

Comparative Map Data
Ttk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39983,716,704 - 83,754,443 (+)NCBIGRCm39mm39
GRCm39 Ensembl983,716,742 - 83,754,442 (+)Ensembl
GRCm38983,834,651 - 83,872,390 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl983,834,689 - 83,872,389 (+)EnsemblGRCm38mm10GRCm38
MGSCv37983,728,296 - 83,765,997 (+)NCBIGRCm37mm9NCBIm37
MGSCv36983,631,459 - 83,669,102 (+)NCBImm8
Celera980,934,680 - 80,972,688 (+)NCBICelera
Cytogenetic Map9E2NCBI
TTK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl680,003,887 - 80,042,527 (+)EnsemblGRCh38hg38GRCh38
GRCh38680,004,147 - 80,042,651 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37680,714,366 - 80,752,244 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36680,771,078 - 80,808,958 (+)NCBINCBI36hg18NCBI36
Build 34680,771,077 - 80,808,956NCBI
Celera681,132,293 - 81,170,226 (+)NCBI
Cytogenetic Map6q14.1NCBI
HuRef677,937,044 - 77,974,979 (+)NCBIHuRef
CHM1_1680,811,776 - 80,849,705 (+)NCBICHM1_1
Ttk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2884,754,329 - 84,792,653 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl884,754,315 - 84,792,651 (+)Ensembl
Rnor_6.0891,368,065 - 91,405,995 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl891,368,111 - 91,405,993 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0890,886,724 - 90,924,327 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4888,906,665 - 88,944,613 (+)NCBIRGSC3.4rn4RGSC3.4
Celera884,402,963 - 84,441,218 (+)NCBICelera
Cytogenetic Map8q31NCBI
Ttk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555027,824,194 - 7,866,879 (+)NCBIChiLan1.0ChiLan1.0
TTK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1681,158,143 - 81,196,478 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl681,158,143 - 81,196,478 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0677,887,382 - 77,925,737 (+)NCBIMhudiblu_PPA_v0panPan3
TTK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11240,915,733 - 40,959,423 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1240,915,439 - 40,957,279 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1240,787,409 - 40,829,802 (+)NCBI
ROS_Cfam_1.01241,678,975 - 41,721,444 (+)NCBI
UMICH_Zoey_3.11240,992,362 - 41,034,814 (+)NCBI
UNSW_CanFamBas_1.01240,969,244 - 41,011,626 (+)NCBI
UU_Cfam_GSD_1.01241,120,015 - 41,162,453 (+)NCBI
Ttk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494676,256,203 - 76,303,738 (+)NCBI
SpeTri2.0NW_00493651010,176,968 - 10,213,483 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl186,076,583 - 86,125,718 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1186,076,576 - 86,125,334 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2196,781,685 - 96,828,277 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TTK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1134,738,849 - 4,779,563 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl134,738,959 - 4,780,627 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666040180,959,238 - 181,026,938 (+)NCBIVero_WHO_p1.0
Ttk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248196,631,697 - 6,682,181 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH125325  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38983,872,062 - 83,872,177UniSTSGRCm38
MGSCv37983,765,669 - 83,765,784UniSTSGRCm37
Celera980,972,360 - 80,972,475UniSTS
Cytogenetic Map9E2UniSTS
M86377  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38983,872,070 - 83,872,167UniSTSGRCm38
MGSCv37983,765,677 - 83,765,774UniSTSGRCm37
Celera980,972,368 - 80,972,465UniSTS
Cytogenetic Map9E2UniSTS
Whitehead/MRC_RH9817.22UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93739490198819654Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49541121101528921Mouse
14746993Manh66_mmandible shape 66 (mouse)94990676683906766Mouse
1301184Bdln4_mbody length 4 (mouse)Not determined95024403884244166Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95212317899910428Mouse
12790990Tgl7_mtriglyceride 7 (mouse)95465267888652678Mouse
10043877Adip21_madiposity 21 (mouse)Not determined95653182690531973Mouse
4141676Neogq1_mneonatal growth QTL 1 (mouse)Not determined95789776486239920Mouse
1301172Fembrs6_mfemur breaking strength 6 (mouse)Not determined95911710593117252Mouse
1301803Stheal9_msoft tissue heal 9 (mouse)Not determined95911710593117252Mouse
5491195Mobq8_mmultigenic obesity QTL 8 (mouse)Not determined95946266493462846Mouse
1300848Skull13_mskull morphology 13 (mouse)Not determined95946266493462846Mouse
1301456Adip5_madiposity 5 (mouse)Not determined95946266493462846Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959990000109260000Mouse
1301611Lrnx3_mlearning contextual 3 (mouse)Not determined96224248596242599Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
11081165Psl6_mpromotion susceptibility QTL 6 (mouse)96513390995640755Mouse
1301290Smgd1_msubmucosal gland distribution 1 (mouse)Not determined96592377486695914Mouse
1301636Lith5_mlithogenic gene 5 (mouse)Not determined966207024100207122Mouse
10045638Heal29_mwound healing/regeneration 29 (mouse)Not determined967124167101124167Mouse
1357610Vtbt8_mvertebral trabecular bone trait 8 (mouse)Not determined968897510102897652Mouse
1301924Bmd10_mbone mineral density 10 (mouse)Not determined968897510102897652Mouse
1301302Pas4_mpulmonary adenoma susceptibility 4 (mouse)Not determined969239845103239920Mouse
10412174Habiir4_mhyperoxic acute lung injury imprinted region 4 (mouse)Not determined96936046598819654Mouse
1301621Hpic1_mhaloperidol-induced catalepsy 1 (mouse)Not determined969546513103546645Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972977005106977152Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972977005106977152Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974368177108368325Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975775364114474379Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975775364114474379Mouse
1301869Tbbmd4_mtotal body bone mineral density 4 (mouse)Not determined976117105101528921Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976535936110536130Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978640645112640755Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979397810113397888Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981798268115798392Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982910333116910428Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982910333116910428Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982910333116910428Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:80
Count of miRNA genes:72
Interacting mature miRNAs:77
Transcripts:ENSMUST00000070326
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001110265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001284272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006511058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006511060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC124011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK084241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV247639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW553739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX775731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY729362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DT914108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV648812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV659530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M86377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000070326   ⟹   ENSMUSP00000064839
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl983,716,771 - 83,754,439 (+)Ensembl
GRCm38.p6 Ensembl983,834,718 - 83,872,386 (+)Ensembl
RefSeq Acc Id: ENSMUST00000185913   ⟹   ENSMUSP00000139956
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl983,716,743 - 83,754,442 (+)Ensembl
GRCm38.p6 Ensembl983,834,690 - 83,872,389 (+)Ensembl
RefSeq Acc Id: ENSMUST00000186277
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl983,716,794 - 83,726,480 (+)Ensembl
GRCm38.p6 Ensembl983,834,741 - 83,844,427 (+)Ensembl
RefSeq Acc Id: ENSMUST00000188445
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl983,716,742 - 83,751,546 (+)Ensembl
GRCm38.p6 Ensembl983,834,689 - 83,869,493 (+)Ensembl
RefSeq Acc Id: ENSMUST00000189727
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl983,716,787 - 83,719,588 (+)Ensembl
GRCm38.p6 Ensembl983,834,734 - 83,837,535 (+)Ensembl
RefSeq Acc Id: ENSMUST00000191484   ⟹   ENSMUSP00000139900
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl983,716,819 - 83,725,144 (+)Ensembl
GRCm38.p6 Ensembl983,834,766 - 83,843,091 (+)Ensembl
RefSeq Acc Id: NM_001110265   ⟹   NP_001103735
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39983,716,742 - 83,751,546 (+)NCBI
GRCm38983,834,689 - 83,869,493 (+)NCBI
MGSCv37983,728,296 - 83,765,997 (+)RGD
Celera980,934,680 - 80,972,688 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001284272   ⟹   NP_001271201
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39983,716,742 - 83,754,443 (+)NCBI
GRCm38983,834,689 - 83,872,390 (+)NCBI
Celera980,934,680 - 80,972,688 (+)NCBI
Sequence:
RefSeq Acc Id: NM_009445   ⟹   NP_033471
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39983,716,742 - 83,754,443 (+)NCBI
GRCm38983,834,689 - 83,872,390 (+)NCBI
MGSCv37983,728,296 - 83,765,997 (+)RGD
Celera980,934,680 - 80,972,688 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006511058   ⟹   XP_006511121
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39983,716,705 - 83,754,442 (+)NCBI
GRCm38983,834,652 - 83,872,389 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006511060   ⟹   XP_006511123
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39983,716,704 - 83,750,272 (+)NCBI
GRCm38983,834,651 - 83,868,132 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033471   ⟸   NM_009445
- Peptide Label: isoform 1
- UniProtKB: Q8BX21 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001103735   ⟸   NM_001110265
- Peptide Label: isoform 2
- UniProtKB: Q8BY97 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001271201   ⟸   NM_001284272
- Peptide Label: isoform 3
- UniProtKB: Q3TPW2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006511123   ⟸   XM_006511060
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006511121   ⟸   XM_006511058
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000064839   ⟸   ENSMUST00000070326
RefSeq Acc Id: ENSMUSP00000139900   ⟸   ENSMUST00000191484
RefSeq Acc Id: ENSMUSP00000139956   ⟸   ENSMUST00000185913
Protein Domains
Protein kinase

Promoters
RGD ID:6845287
Promoter ID:MM_KWN:58236
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001110265,   NM_009445,   UC009QWP.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36983,727,826 - 83,728,326 (+)MPROMDB
RGD ID:8670340
Promoter ID:EPDNEW_M13200
Type:initiation region
Name:Ttk_1
Description:Mus musculus Ttk protein kinase , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38983,834,699 - 83,834,759EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1194921 AgrOrtholog
Ensembl Genes ENSMUSG00000038379 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000064839 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000139900 UniProtKB/TrEMBL
  ENSMUSP00000139956 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000070326 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000185913 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000188445 ENTREZGENE
  ENSMUST00000191484 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kin_Mps1_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22137 UniProtKB/TrEMBL
MGD MGI:1194921 ENTREZGENE
NCBI Gene 22137 ENTREZGENE
PANTHER PTHR22974:SF21 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ttk PhenoGen
PROSITE PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WPS8_MOUSE UniProtKB/TrEMBL
  P35761 ENTREZGENE
  Q3TPW2 ENTREZGENE, UniProtKB/TrEMBL
  Q6PD96_MOUSE UniProtKB/TrEMBL
  Q8BX21 ENTREZGENE, UniProtKB/TrEMBL
  Q8BY97 ENTREZGENE, UniProtKB/TrEMBL
  TTK_MOUSE UniProtKB/Swiss-Prot