Haspin (histone H3 associated protein kinase)

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Gene: Haspin (histone H3 associated protein kinase) Mus musculus

Analyze

Symbol:

Haspin

Name:

histone H3 associated protein kinase

RGD ID:

1620119

MGI Page

MGI

Description:

Orthologous to human HASPIN (histone H3 associated protein kinase); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

germ cell associated 2, haspin; germ cell-specific gene 2; germ cell-specific gene 2 protein; Gsg; Gsg2; haploid germ cell-specific nuclear protein kinase; MGC130563; serine/threonine-protein kinase haspin

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HASPIN (histone H3 associated protein kinase)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Haspin (histone H3 associated protein kinase)	HGNC	EggNOG, NCBI, OMA, HomoloGene, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Haspin (histone H3 associated protein kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HASPIN (histone H3 associated protein kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	HASPIN (histone H3 associated protein kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Haspin (histone H3 associated protein kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	HASPIN (histone H3 associated protein kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	HASPIN (histone H3 associated protein kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Haspin (histone H3 associated protein kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	HASPIN (histone H3 associated protein kinase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Rattus norvegicus (Norway rat):	Haspin (histone H3 associated protein kinase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Danio rerio (zebrafish):	si:dkeyp-26a9.2	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Saccharomyces cerevisiae (baker's yeast):	ALK1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	ALK2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB\|Roundup)
Drosophila melanogaster (fruit fly):	Haspin	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Caenorhabditis elegans (roundworm):	hasp-2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Caenorhabditis elegans (roundworm):	hasp-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	Y73B6A.1	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	ZK177.2	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	VY10G11R.1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	Y48B6A.10	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	C04G2.10	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	C26E6.1	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	73,026,310 - 73,029,120 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	11	73,026,311 - 73,029,120 (-)	Ensembl
GRCm38	11	73,135,484 - 73,138,294 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	73,135,485 - 73,138,294 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	72,948,986 - 72,951,796 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	11	72,951,680 - 72,954,489 (-)	NCBI			mm8
Celera	11	80,669,945 - 80,672,755 (-)	NCBI		Celera
Cytogenetic Map	11	B4	NCBI
cM Map	11	45.25	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Canavan disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

1-naphthyl isothiocyanate (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (EXP)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3-methylcholanthrene (EXP)

4-hydroxynon-2-enal (EXP)

6-propyl-2-thiouracil (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

aflatoxin B2 (ISO)

amphetamine (ISO)

arsenite(3-) (EXP)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (EXP)

bisphenol A (ISO)

calcitriol (ISO)

carbon nanotube (EXP)

coumestrol (ISO)

dibutyl phthalate (EXP)

dicrotophos (ISO)

dioxygen (ISO)

gamma-tocopherol (EXP)

leflunomide (ISO)

paracetamol (ISO)

PCB138 (EXP)

pregnenolone 16alpha-carbonitrile (EXP)

propanal (ISO)

resveratrol (ISO)

silicon dioxide (EXP)

sunitinib (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

titanium dioxide (EXP)

tocopherol (EXP)

trimellitic anhydride (EXP)

troglitazone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chromatin organization (IEA)

histone H3-T3 phosphorylation (IBA)

histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore (ISO)

intracellular signal transduction (IBA,IDA,ISO)

mitotic cell cycle (IBA)

mitotic sister chromatid cohesion (ISO)

negative regulation of G1/S transition of mitotic cell cycle (IDA)

phosphorylation (IEA)

protein localization to chromosome, centromeric region (ISO)

protein phosphopantetheinylation (IBA)

protein phosphorylation (IDA,ISO)

Cellular Component

centrosome (ISO)

chromosome (IEA)

cytoplasm (IBA)

cytoskeleton (IEA)

nucleoplasm (ISO)

nucleus (IBA,IDA,ISO)

spindle (ISO)

Molecular Function

ATP binding (IDA,ISO)

DNA binding (IDA)

histone kinase activity (H3-T3 specific) (IBA,ISO)

kinase activity (IEA)

nucleotide binding (IEA)

protein binding (ISO)

protein kinase activity (ISO)

protein serine/threonine kinase activity (IDA)

transferase activity (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal male germ cell morphology (IAGP)

References

References - curated


1.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:1683707	PMID:7619729	PMID:7957958	PMID:9337410	PMID:9398437	PMID:10349636	PMID:10358056	PMID:11042159	PMID:11076861	PMID:11217851	PMID:11228240	PMID:11311555
PMID:11311556	PMID:12466851	PMID:12477932	PMID:15681610	PMID:16141072	PMID:16141073	PMID:17123944	PMID:21267068	PMID:21606629	PMID:21677750	PMID:21873635	PMID:25315835
PMID:26410627	PMID:27389782	PMID:27562071	PMID:32325033	PMID:32758484

Genomics

Comparative Map Data

Haspin
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	73,026,310 - 73,029,120 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	11	73,026,311 - 73,029,120 (-)	Ensembl
GRCm38	11	73,135,484 - 73,138,294 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	73,135,485 - 73,138,294 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	72,948,986 - 72,951,796 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	11	72,951,680 - 72,954,489 (-)	NCBI			mm8
Celera	11	80,669,945 - 80,672,755 (-)	NCBI		Celera
Cytogenetic Map	11	B4	NCBI
cM Map	11	45.25	NCBI

HASPIN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	17	3,723,903 - 3,726,699 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	17	3,723,903 - 3,726,699 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	17	3,627,197 - 3,629,993 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	3,573,946 - 3,576,742 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	17	3,573,945 - 3,576,742	NCBI
Celera	17	3,638,895 - 3,641,691 (+)	NCBI
Cytogenetic Map	17	p13.2	NCBI
HuRef	17	3,517,398 - 3,520,194 (+)	NCBI		HuRef
CHM1_1	17	3,636,500 - 3,639,296 (+)	NCBI		CHM1_1

Haspin
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	57,747,731 - 57,750,532 (-)	NCBI
Rnor_6.0 Ensembl	10	59,695,913 - 59,698,168 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	10	59,695,403 - 59,698,398 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	10	59,434,870 - 59,437,669 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	10	56,871,875 - 56,874,870 (-)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

Haspin
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955467	13,078,346 - 13,104,241 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955467	13,099,958 - 13,104,337 (-)	NCBI	ChiLan1.0	ChiLan1.0

HASPIN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	17	3,767,364 - 3,770,167 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	3,767,404 - 3,769,800 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	17	3,772,899 - 3,775,903 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

HASPIN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	9	47,540,446 - 47,542,791 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	9	47,540,417 - 47,542,953 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Haspin
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936677	401,198 - 404,472 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HASPIN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	12	49,820,435 - 49,823,515 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

HASPIN
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	3,226,292 - 3,229,349 (+)	NCBI
ChlSab1.1 Ensembl	16	3,226,582 - 3,228,978 (+)	Ensembl

Haspin
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624786	6,371,639 - 6,374,517 (+)	NCBI

Position Markers

UniSTS:237527

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	11	73,136,100 - 73,136,309	UniSTS	GRCm38
MGSCv37	11	72,949,602 - 72,949,811	UniSTS	GRCm37
Celera	11	80,670,561 - 80,670,770	UniSTS
Cytogenetic Map	11	B4	UniSTS
cM Map	11	44.0	UniSTS
cM Map	11	47.0	UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
13208559	Wght10_m	weight 10 (mouse)					11	4000000	89000000	Mouse
13208558	Lgth12_m	body length 12 (mouse)					11	4000000	95000000	Mouse
1300905	Scc6_m	colon tumor susceptibility 6 (mouse)			Not determined		11	6930277	89128908	Mouse
1357859	Lvrq7_m	liver weight QTL 7 (mouse)			Not determined		11	12318637	118131898	Mouse
39128214	Lwq20_m	liver weight QTL 20 (mouse)					11	12318637	118131898	Mouse
4141894	Nidd6k_m	Nidd6 on KK-A (mouse)			Not determined			19174204	97007000	Mouse
10412246	Dfs2_m	dental fluorosis suseptibility 2 (mouse)			Not determined		11	21857364	95990405	Mouse
13208569	Bmiq10_m	body mass index QTL 10 (mouse)					11	36000000	85000000	Mouse
1301328	Mol4_m	modifier of LPS-response 4 (mouse)			Not determined		11	36391750	83590530	Mouse
11532698	Sluc36a_m	susceptibility to lung cancer 36a (mouse)					11	42365791	76365904	Mouse
11532699	Sluc36b_m	susceptibility to lung cancer 36b (mouse)					11	42365791	76365904	Mouse
4142300	Ctrq3_m	C. trachomatis resistance QTL 3 (mouse)			Not determined		11	44739211	76963931	Mouse
4141367	Inf1_m	acute ozone induced inflammation (mouse)			Not determined			44739211	113167183	Mouse
4141000	Nidd3_m	non-insulin-dependent diabetes mellitus 3 (mouse)			Not determined			45151201	79151308	Mouse
1302021	Nidd1n_m	non-insulin-dependent diabetes mellitus 1 in NSY (mouse)			Not determined		11	45275046	80087498	Mouse
1357878	Mastr_m	modifier of astrocytoma (mouse)			Not determined		11	45817754	89927907	Mouse
1300765	Bbaa4_m	B.burgdorferi-associated arthritis 4 (mouse)			Not determined		11	46294341	80294436	Mouse
1301988	Bmd11_m	bone mineral density 11 (mouse)			Not determined		11	46428581	80428696	Mouse
1301830	Ssta4_m	susceptibility to Salmonella typhimurium antigens 4 (mouse)			Not determined		11	50187365	84187585	Mouse
13524840	Ppiq9a_m	prepulse inhibition QTL 9a (mouse)					11	52603559	86603559	Mouse
1300774	Pgia7_m	proteoglycan induced arthritis 7 (mouse)			Not determined		11	53499762	87499911	Mouse
4141830	Pregq1_m	pregnancy QTL 1 (mouse)			Not determined		11	54235926	83842826	Mouse
4142121	Tmc1m2_m	Tmc1 modifier 2 (mouse)			Not determined		11	56973201	114267131	Mouse
1300664	Etohcta9_m	ethanol conditioned taste aversion 9 (mouse)			Not determined		11	57863834	91863932	Mouse
10053682	Eae45_m	experimental allergic encephalomyelitis susceptibility 45 (mouse)			Not determined		11	58599729	74863932	Mouse
1300924	Ity2_m	immunity to S. typhimurium 2 (mouse)			Not determined		1	58617204	87804412	Mouse
4141982	Skts-fp2_m	skin tumor susceptibility in FVB and PWK 2 (mouse)			Not determined			58828440	85175703	Mouse
1301987	Pid3_m	prior incubation determinant 3 (mouse)			Not determined		11	61795994	88808902	Mouse
1301319	Dautb4_m	dopamine uptake transporter binding 4 (mouse)			Not determined		11	62265179	96265327	Mouse
27226730	Tibmd1_m	tibia midshaft diameter 1, 5 week (mouse)					11	62700000	109500000	Mouse
1301999	Lmr15_m	leishmaniasis resistance 15 (mouse)			Not determined		11	63428581	81939647	Mouse
10044004	Stzid3_m	streptozotocin induced diabetes susceptibility 3 (mouse)			Not determined		11	63428581	94173092	Mouse
11039501	Ltpr6a_m	Leishmania tropica response 6a (mouse)					11	64939510	98939647	Mouse
11039502	Ltpr6b_m	Leishmania tropica response 6b (mouse)					11	64939510	98939647	Mouse
11039515	Ltpr6_m	Leishmania tropica response 6 (mouse)					11	64939510	98939647	Mouse
1301546	Pcir2_m	periosteal circumference 2 (mouse)			Not determined		11	66842594	100842826	Mouse
1357766	Si5lq6_m	serum IGFBP-5 level QTL 6 (mouse)			Not determined		11	66842594	100842826	Mouse
4141012	Femwf6_m	femur work to failure 6 (mouse)			Not determined			66842594	100842826	Mouse
1301833	Tbbmd5_m	total body bone mineral density 5 (mouse)			Not determined		11	66842594	100842826	Mouse
1300784	Prdt3_m	prion disease incubation time 3 (mouse)			Not determined		11	66842594	100842826	Mouse
1300628	Lgth6_m	body length 6 (mouse)			Not determined		11	66842594	100842826	Mouse
4142316	Ity2b_m	immunity to S. typhimurium 2b (mouse)			Not determined		11	67187365	79923086	Mouse
27226783	Tibl5_m	tibia length 5, 5 week (mouse)					11	68300000	102000000	Mouse
1300651	Pcyts3_m	plasmacytoma susceptibility 3 (mouse)			Not determined		11	70800372	104800540	Mouse
1301681	Sle13_m	systematic lupus erythematosus susceptibility 13 (mouse)			Not determined		11	70800372	104800540	Mouse
1558812	Rafar_m	retinoic acid induced forelimb autopod reduction (mouse)			Not determined		11	70800372	104800540	Mouse
4141339	Nilac2_m	nicotine induced locomotor activity 2 (mouse)			Not determined		11	70800372	104800540	Mouse
1301404	Sbmd4_m	spinal bone mineral density 4 (mouse)			Not determined		11	72128823	106128908	Mouse
1301078	Alcp2_m	alcohol preference locus 2 (mouse)			Not determined		11	72318970	84840636	Mouse
1301310	Tmevd5_m	Theiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)			Not determined		11	72835299	106835463	Mouse
4142348	Pstc2_m	periosteal circumference 2 (mouse)			Not determined		11	72927789	106927907	Mouse
10043866	Adip19_m	adiposity 19 (mouse)			Not determined		11	72927789	106927907	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	198
Count of miRNA genes:	156
Interacting mature miRNAs:	175
Transcripts:	ENSMUST00000052140
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_010353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB036930	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF289866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AI450094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK138750	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL670399	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AV143145	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC113148	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466596	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU234134	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D87326	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000052140 ⟹ ENSMUSP00000055806

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	11	73,135,485 - 73,138,294 (-)	Ensembl

RefSeq Acc Id:

NM_010353 ⟹ NP_034483

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	73,026,310 - 73,029,120 (-)	NCBI
GRCm38	11	73,135,484 - 73,138,294 (-)	ENTREZGENE
MGSCv37	11	72,948,986 - 72,951,796 (-)	RGD
Celera	11	80,669,945 - 80,672,755 (-)	RGD
cM Map	11		ENTREZGENE

Sequence:

show sequence

GTTTCTGTTTGAAACGCCGGGCGGGCGCTCGCTATGGCACAGGCTCACCCGCGGTCGGGTACCC
GGCTCTTTCGAACGTACGCGGCGAGGGGCGTCCGGGGGTCGCAGCGGCAGCCTGGCGGGCTGGC
TGAGCAATGGTTCCAGCCGCCGAACCTGAAGCGCGCCTTCAGCAGCAGCCTCAGCGACAGTAAC
GAGTCGCCGGCTGTCGCTTCCGACGACCCGGACGACCCCGACTTCCCCGGCAGCCTCGTGGGCC
AGCGGCGGAGGCGTCCTCGGGGCAGCGGCTCCCGGAACCAGCGGACCCTGACAAACACTCCAAG
AGTCCAAAGGCTGCGACCTCGGCTCCCGCAGAAGTGCAGCACCCCGTGCAGCCGGCTGCGACCG
CCACCTTTCCCCAACTGCAGCCCGGGCTGCCTCGGGTCGGACCACAGTGTGTGCATCCAGTCCA
GGGACAGCAACGAGCTGGGCACCAGTGCCTCCCTCTTCAGCTCTCCGGCCTCGCCCGGAGCCCC
CGACCCTTTGTATGCTGACTCTGCAGTCCCCGGGAGCTTCCACTTGCCGGCAGCCTCCCTAAGT
GAACCGTCTGTGCCCTGCCCCCAGGTGGCAGCAACCGGTGACAGGTACACCGGGAGGGCCCTCC
GAGCCGAAGCCAGCTTCAGGTCATCTCTCTTTAGCCTTGTGAACTCAGGGGCCACAGAAGAGAA
CAAGTTTGGGACAGATGGGGAGAATGTGAAGGAATCGTGTTGTGAAAGAAGACAGCAGATGGGA
AACAGACTAACGGACCCTGATCTGACAAGCCCGGGAAAGAGAAAGGCCGCGTGTAAAAAGGTTG
TGTCCCAAGGAGTCGACCAGAGAGACTATGAGGAGTCCAGTGCTTGCAAAGACCTTCGTGTACC
AGGGGAAATCAGCAGGCCTAAGAGAACTGGGCCACTCCGGAAGAGGAAACAGCAAGAAGCAACG
GGAACCCCTCCCCGCCACTACCACCAATCTAAGAAGAAAAGGAAAGCGTCAGTCTCCTTATGGA
ACTTGAATACTAGCCAGAGGGATTCTTGGACCAAAACCAGAGCCTCCTTCGGTTTCCACAAGAA
GAAAATTATAACCAGTGTGATAGAGGTATGCAGTTCTGTTGCCAGTTCTTCCTCCAGGTCCCTC
CTGTCTGAATGTTCGACCCCTCCTATCAAGAACAGAGCACACCTTACTGTTTCTTCTCGATGCT
CTTCTGTGTATTTGCTAAGTCCCTTAAAGACCCTGCATGTCACAGACCAAAGGCCATCTTATGC
TGAAAAGGTTTATGGGGAGTGTAATCAGGAAGGGCCCATCCCCTTTAGTGATTGCCTTTCCACG
GAAAAACTGGAACGGTGTGAGAAGATTGGGGAAGGAGTGTTTGGAGAAGTGTTTCAGATAATTA
ACGACCAAGCACCTGTAGCCCTAAAAATCATTGCTATTGAAGGGTTAGATTTAGTCAATGGGTC
CCACCAGAAAACCTTTGAGGAAATCCTGCCGGAGATCATTATCTCCAAAGAGCTGAGTCTCTTG
TCTAGTGAGGCCTACAACCGCACAGAAGGCTTTATTGGGCTGAACTCAGTACACTGTGTTCAAG
GGCTTTACCCTCCCTTGCTGCTGAAAGCCTGGGATCACTATAACACAACCAAAAGATCTGCCAA
TGACCGGCCTGACTTTTTCCAGGAAGACCAGCTCTTTATTATCCTGGAATTTGAGTTTGGTGGG
GTTGACTTGGAGCGAATGAAAACCAAGCTGTCCTCTGTGGCGACTGCAAAGAGCATTCTCCACC
AGATCACTGCATCTCTGGCTGTGGCAGAAGCATCCCTGCACTTTGAGCACCGGGACTTACACTG
GGGAAATGTGCTCTTAAAGAAAACCAACCTCAAAGAACTCCGCTACACCCTCAATGGGAAAACG
AGCACCATTCCCACCCATGGGCTACAGGTCAACATCATTGACTACACCCTGTCCCGCTTGGAGC
GGGATGGGATTGTGGTTTTCTGTGATATCTCCGCTGAAGAGGACCTATTTACAGGTGAGGGTGA
CTACCAGTTTGAGATCTACAGGCTCATGAGGAAGGAGAACAAAAACTGCTGGGGTGAGTATCAC
CCTTACAATAATGTGCTGTGGCTGCATTACCTCACAGACAAGATTCTGAATAAGATGAAATTTA
AGACTAAATGCCAGAGCGCAGCCATGAAGCAAATAAGGAAAAACCTGCAACATTTCCACAGGAC
TGTACTGAGTTTCAGCTCTGCCACGGACCTGCTCTGCCAACACAGTCTATTTAGGTAAGCCAGG
AACTTAGACTTTCAGAGCCTCTTTAAGTACACTTTTAGGCCTCTGGTACTAATCTCTGCCACTA
GAGCCAGATGGAGGTGAAAGCACATCCTTAAGAGTTCCTGTCAGCTTCTTAAAAGAGAACTGTG
TTTTTCAAAAGGTAACCAAAACATTTGTTGACATGATTAAACTTGCTTTTAACAAATGTTCCTC
TTTTTTAAAAAAAAAAATAAACTAGACAGAGGACAAGTGGACACATCTTTAAGTCCTCGTCCTG
TCAGCAGAGTCTACAAGTCTGATGTTGCTGGTTTTTGAGCCTTGATACTTGGTGTAGGATGAGC
AAAACCAAGCCTCAGCTGTGGTCCTTACTGCTCTTGATGCTGTTGTCAAGATGCAGAGCAGAGA
GCAAGAGACTAGAGAGTCAAAACCAAGAGAAAGTATGGAAAATGTTTATCCGGTTCACTCCCCA
ATCACAGGAGCAGAATTTATAGAATTTCAACAGGAAAATAAATGTCTCTGTGGCTCTCAAAAAA
AA

hide sequence

Protein Sequences


Protein RefSeqs	NP_034483	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI13149	(Get FASTA)	NCBI Sequence Viewer
	AAK30301	(Get FASTA)	NCBI Sequence Viewer
	BAA75494	(Get FASTA)	NCBI Sequence Viewer
	BAB00640	(Get FASTA)	NCBI Sequence Viewer
	BAE23768	(Get FASTA)	NCBI Sequence Viewer
	EDL12710	(Get FASTA)	NCBI Sequence Viewer
	Q9Z0R0	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_034483 ⟸ NM_010353

- UniProtKB:

Q9Z0R0 (UniProtKB/Swiss-Prot), A0A0R4J0P2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAQAHPRSGTRLFRTYAARGVRGSQRQPGGLAEQWFQPPNLKRAFSSSLSDSNESPAVASDDPD
DPDFPGSLVGQRRRRPRGSGSRNQRTLTNTPRVQRLRPRLPQKCSTPCSRLRPPPFPNCSPGCL
GSDHSVCIQSRDSNELGTSASLFSSPASPGAPDPLYADSAVPGSFHLPAASLSEPSVPCPQVAA
TGDRYTGRALRAEASFRSSLFSLVNSGATEENKFGTDGENVKESCCERRQQMGNRLTDPDLTSP
GKRKAACKKVVSQGVDQRDYEESSACKDLRVPGEISRPKRTGPLRKRKQQEATGTPPRHYHQSK
KKRKASVSLWNLNTSQRDSWTKTRASFGFHKKKIITSVIEVCSSVASSSSRSLLSECSTPPIKN
RAHLTVSSRCSSVYLLSPLKTLHVTDQRPSYAEKVYGECNQEGPIPFSDCLSTEKLERCEKIGE
GVFGEVFQIINDQAPVALKIIAIEGLDLVNGSHQKTFEEILPEIIISKELSLLSSEAYNRTEGF
IGLNSVHCVQGLYPPLLLKAWDHYNTTKRSANDRPDFFQEDQLFIILEFEFGGVDLERMKTKLS
SVATAKSILHQITASLAVAEASLHFEHRDLHWGNVLLKKTNLKELRYTLNGKTSTIPTHGLQVN
IIDYTLSRLERDGIVVFCDISAEEDLFTGEGDYQFEIYRLMRKENKNCWGEYHPYNNVLWLHYL
TDKILNKMKFKTKCQSAAMKQIRKNLQHFHRTVLSFSSATDLLCQHSLFR

hide sequence

RefSeq Acc Id:

ENSMUSP00000055806 ⟸ ENSMUST00000052140

Protein Domains

Protein kinase

Promoters

RGD ID:

6821035

Promoter ID:

MM_KWN:8358

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, ES_Cell, Kidney, Lung, Spleen

Transcripts:

NM_010353

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	11	72,951,491 - 72,951,991 (-)	MPROMDB

RGD ID:

8675474

Promoter ID:

EPDNEW_M15768

Type:

initiation region

Name:

Haspin_1

Description:

Mus musculus histone H3 associated protein kinase , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	11	73,138,284 - 73,138,344	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1194498	AgrOrtholog
Ensembl Genes	ENSMUSG00000050107	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000055806	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000052140	ENTREZGENE, UniProtKB/TrEMBL
InterPro	Kinase-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Prot_kinase_cat_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:14841	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:1194498	ENTREZGENE
NCBI Gene	14841	ENTREZGENE
PhenoGen	Haspin	PhenoGen
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	S_TKc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Kinase_like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0R4J0P2	ENTREZGENE, UniProtKB/TrEMBL
	HASP_MOUSE	UniProtKB/Swiss-Prot
	Q2KHL1_MOUSE	UniProtKB/TrEMBL
	Q3UU60_MOUSE	UniProtKB/TrEMBL
	Q9Z0R0	ENTREZGENE
UniProt Secondary	Q99MU9	UniProtKB/Swiss-Prot
	Q9JJJ4	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-06-13	Haspin	histone H3 associated protein kinase	Gsg2	germ cell associated 2, haspin	Symbol and/or name change	5135510	APPROVED
2016-06-30	Gsg2	germ cell associated 2, haspin		germ cell-specific gene 2	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar