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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:myricetin
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Accession:CHEBI:18152 term browser browse the term
Definition:A hexahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 3', 4', 5, 5' and 7. It has been isolated from the leaves of Myrica rubra and other plants.
Synonyms:exact_synonym: 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one
 related_synonym: 3,3',4',5,5',7-Hexahydroxyflavone;   Cannabiscetin;   Formula=C15H10O8;   InChI=1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H;   InChIKey=IKMDFBPHZNJCSN-UHFFFAOYSA-N;   Myricetol;   SMILES=Oc1cc(O)c2c(c1)oc(-c1cc(O)c(O)c(O)c1)c(O)c2=O
 alt_id: CHEBI:14636;   CHEBI:44341;   CHEBI:7053
 xref: Beilstein:332331;   CAS:529-44-2;   DrugBank:DB02375;   HMDB:HMDB0002755;   KEGG:C10107;   KNApSAcK:C00001071;   LINCS:LSM-2957;   LIPID_MAPS_instance:LMPK12110001
 xref_mesh: MESH:C040015
 xref: MetaCyc:MYRICETIN;   PDBeChem:MYC;   PMID:19407970;   PMID:19778600;   PMID:22482362;   PMID:23099505;   PMID:23232835;   PMID:23265454;   PMID:23736695;   Reaxys:332331;   Wikipedia:Myricetin
 cyclic_relationship: is_conjugate_acid_of CHEBI:58395



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myricetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions
increases expression
increases activity
EXP myricetin inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]
myricetin results in increased expression of ABCB1 protein
myricetin results in increased activity of ABCB1 protein
CTD PMID:34217736 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) decreases activity
multiple interactions
EXP myricetin results in decreased activity of ABCC1 protein
myricetin inhibits the reaction [ABCC1 protein affects the export of and results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC1 protein affects the export of Vincristine]; myricetin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC1 protein results in increased uptake of Leukotriene C4]
CTD PMID:11306701 PMID:15670588 PMID:15896345 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 multiple interactions
decreases activity
EXP myricetin inhibits the reaction [ABCC2 protein affects the export of and results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC2 protein affects the export of Vincristine]; myricetin inhibits the reaction [ABCC2 protein results in decreased susceptibility to Vincristine]
myricetin results in decreased activity of ABCC2 protein
CTD PMID:15670588 PMID:15896345 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
JBrowse link
G AFP alpha fetoprotein affects binding ISO myricetin binds to AFP protein CTD PMID:23013281 PMID:25349334 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174
JBrowse link
G ALB albumin multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of ALB protein] CTD PMID:24923654 PMID:25240712 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ARHGDIB Rho GDP dissociation inhibitor beta increases cleavage EXP myricetin results in increased cleavage of ARHGDIB protein CTD PMID:15748703 NCBI chr12:14,942,015...14,961,601
Ensembl chr12:14,942,031...14,961,728
JBrowse link
G ATR ATR serine/threonine kinase multiple interactions EXP myricetin affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of ATR mRNA] CTD PMID:32342131 NCBI chr 3:142,449,235...142,578,733
Ensembl chr 3:142,449,007...142,578,733
JBrowse link
G BAX BCL2 associated X, apoptosis regulator decreases expression
multiple interactions
EXP myricetin results in decreased expression of BAX protein
Tetradecanoylphorbol Acetate inhibits the reaction [myricetin results in decreased expression of BAX protein]
CTD PMID:15748703 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression
multiple interactions
EXP myricetin results in decreased expression of BCL2 protein
Tetradecanoylphorbol Acetate inhibits the reaction [myricetin results in decreased expression of BCL2 protein]
CTD PMID:15748703 PMID:29698783 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G CASP3 caspase 3 increases activity
increases cleavage
EXP myricetin results in increased activity of CASP3 protein
myricetin results in increased cleavage of CASP3 protein
CTD PMID:15748703 PMID:19397994 PMID:29698783 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP8 caspase 8 decreases expression EXP myricetin results in decreased expression of CASP8 protein CTD PMID:29698783 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CASP9 caspase 9 increases activity
increases cleavage
EXP myricetin results in increased activity of CASP9 protein
myricetin results in increased cleavage of CASP9 protein
CTD PMID:15748703 PMID:29698783 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase multiple interactions EXP
ISO
myricetin inhibits the reaction [Rotenone results in increased activity of CAT protein]
myricetin inhibits the reaction [Ethanol results in decreased activity of CAT protein]
CTD PMID:15904944 PMID:35156864 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCNB1 cyclin B1 decreases expression EXP myricetin results in decreased expression of CCNB1 mRNA; myricetin results in decreased expression of CCNB1 protein CTD PMID:19397994 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression EXP myricetin results in increased expression of CDKN1A mRNA; myricetin results in increased expression of CDKN1A protein CTD PMID:19397994 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CDKN2C cyclin dependent kinase inhibitor 2C increases expression EXP myricetin results in increased expression of CDKN2C mRNA CTD PMID:18331776 NCBI chr 1:50,968,706...50,974,634
Ensembl chr 1:50,960,745...50,974,634
JBrowse link
G CFL1 cofilin 1 increases expression EXP myricetin results in increased expression of CFL1 protein CTD PMID:29698783 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
JBrowse link
G CLDN1 claudin 1 multiple interactions ISO myricetin inhibits the reaction [Indomethacin results in decreased expression of CLDN1 mRNA]; myricetin inhibits the reaction [Indomethacin results in decreased expression of CLDN1 protein] CTD PMID:33276066 NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446
JBrowse link
G COMT catechol-O-methyltransferase multiple interactions EXP [myricetin co-treated with COMT protein] results in decreased activity of DNMT1 protein CTD PMID:16037419 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975
JBrowse link
G COX5B cytochrome c oxidase subunit 5B increases expression EXP myricetin results in increased expression of COX5B protein CTD PMID:29698783 NCBI chr 2:97,646,062...97,648,383
Ensembl chr 2:97,646,062...97,648,383
JBrowse link
G CTNNB1 catenin beta 1 decreases expression
multiple interactions
EXP myricetin results in decreased expression of CTNNB1 protein
[myricetin results in increased activity of SIRT1 protein] which results in decreased expression of CTNNB1 protein
CTD PMID:22245592 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CYCS cytochrome c, somatic affects localization
multiple interactions
EXP myricetin affects the localization of CYCS protein
Tetradecanoylphorbol Acetate inhibits the reaction [myricetin affects the localization of CYCS protein]
CTD PMID:15748703 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 multiple interactions ISO myricetin promotes the reaction [Cyclic AMP results in increased expression of CYP11A1 mRNA] CTD PMID:28668616 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases activity
increases expression
multiple interactions
EXP
ISO
myricetin results in decreased activity of CYP1A1 protein
myricetin results in increased expression of CYP1A1 mRNA
myricetin inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
CTD PMID:16271822 PMID:20930378 PMID:21482471 PMID:29584932 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 decreases activity EXP myricetin results in decreased activity of CYP1A2 protein CTD PMID:29753067 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 decreases activity EXP myricetin results in decreased activity of CYP1B1 protein CTD PMID:16271822 PMID:21482471 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 decreases activity EXP myricetin results in decreased activity of CYP2A6 protein CTD PMID:29753067 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 decreases activity EXP myricetin results in decreased activity of CYP2C19 protein CTD PMID:29753067 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 decreases activity EXP myricetin results in decreased activity of CYP2C9 protein CTD PMID:29753067 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 decreases activity EXP myricetin results in decreased activity of CYP2D6 protein CTD PMID:29753067 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 decreases activity EXP myricetin results in decreased activity of CYP2E1 protein CTD PMID:29753067 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 decreases activity EXP myricetin results in decreased activity of CYP3A4 protein CTD PMID:29753067 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G DNMT1 DNA methyltransferase 1 multiple interactions
decreases activity
EXP [myricetin co-treated with COMT protein] results in decreased activity of DNMT1 protein
myricetin results in decreased activity of DNMT1 protein
CTD PMID:16037419 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
JBrowse link
G EGF epidermal growth factor multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased expression of FOS mRNA]; myricetin inhibits the reaction [EGF protein results in increased expression of STAT3 mRNA]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of JAK1 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK9 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KA1 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]; myricetin promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:17693661 PMID:18995957 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G EGFR epidermal growth factor receptor multiple interactions
decreases phosphorylation
ISO myricetin promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein]
myricetin results in decreased phosphorylation of EGFR protein
CTD PMID:18995957 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 decreases expression
multiple interactions
EXP myricetin results in decreased expression of EGLN1 protein
[myricetin results in increased activity of SIRT1 protein] which results in decreased expression of EGLN1 protein
CTD PMID:22245592 NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287
JBrowse link
G EP300 E1A binding protein p300 multiple interactions EXP myricetin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]] CTD PMID:20153296 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077
JBrowse link
G FBP1 fructose-bisphosphatase 1 decreases expression EXP myricetin results in decreased expression of FBP1 mRNA CTD PMID:18331776 NCBI chr 9:94,603,133...94,640,263
Ensembl chr 9:94,603,133...94,640,249
JBrowse link
G FDX1 ferredoxin 1 multiple interactions ISO myricetin promotes the reaction [Cyclic AMP results in increased expression of FDX1 mRNA] CTD PMID:28668616 NCBI chr11:110,429,331...110,464,884
Ensembl chr11:110,429,948...110,464,884
JBrowse link
G FN1 fibronectin 1 multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein] CTD PMID:25240712 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased expression of FOS mRNA]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA] CTD PMID:17693661 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein] CTD PMID:24923654 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572
JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO myricetin inhibits the reaction [Ethanol results in increased activity of GPT protein] CTD PMID:35156864 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions ISO myricetin inhibits the reaction [Ethanol results in decreased activity of GSR protein] CTD PMID:35156864 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G H2AX H2A.X variant histone multiple interactions EXP myricetin inhibits the reaction [Doxorubicin results in increased expression of H2AX protein] CTD PMID:32107588 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465
JBrowse link
G HBEGF heparin binding EGF like growth factor multiple interactions EXP myricetin affects the reaction [Sodium Chloride results in increased expression of HBEGF mRNA] CTD PMID:26800359 NCBI chr 5:140,332,843...140,346,603
Ensembl chr 5:140,332,843...140,346,603
JBrowse link
G HGF hepatocyte growth factor multiple interactions EXP myricetin inhibits the reaction [HGF protein results in increased phosphorylation of MET protein] CTD PMID:19244381 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha increases expression
decreases activity
multiple interactions
EXP myricetin results in increased expression of HIF1A protein
myricetin results in decreased activity of HIF1A protein
[myricetin results in increased activity of SIRT1 protein] which results in increased expression of HIF1A protein; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A protein]; myricetin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]
CTD PMID:19958256 PMID:20153296 PMID:22245592 PMID:36116563 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HK2 hexokinase 2 multiple interactions EXP Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 protein] CTD PMID:36116563 NCBI chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased activity of HMGCR protein] CTD PMID:25240712 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G HMOX1 heme oxygenase 1 increases expression EXP myricetin results in increased expression of HMOX1 protein CTD PMID:16799064 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HRAS HRas proto-oncogene, GTPase decreases activity ISO myricetin results in decreased activity of HRAS protein CTD PMID:17693661 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
JBrowse link
G IL6 interleukin 6 multiple interactions EXP
ISO
myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]
myricetin inhibits the reaction [Ethanol results in increased expression of IL6 protein]
CTD PMID:18958421 PMID:35156864 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of INS1 protein] CTD PMID:24923654 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
JBrowse link
G IRS1 insulin receptor substrate 1 multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS1 protein] CTD PMID:24923654 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820
JBrowse link
G IRS2 insulin receptor substrate 2 multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS2 protein] CTD PMID:24923654 NCBI chr13:109,752,695...109,786,583
Ensembl chr13:109,752,695...109,786,583
JBrowse link
G JAK1 Janus kinase 1 affects binding
multiple interactions
EXP
ISO
myricetin binds to JAK1 protein
myricetin inhibits the reaction [EGF protein results in increased phosphorylation of JAK1 protein]
CTD PMID:18995957 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754
JBrowse link
G LCAT lecithin-cholesterol acyltransferase multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LCAT protein] CTD PMID:25240712 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131
JBrowse link
G LDHA lactate dehydrogenase A multiple interactions EXP Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA protein] CTD PMID:36116563 NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425
JBrowse link
G LPL lipoprotein lipase multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LPL protein] CTD PMID:25240712 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259
JBrowse link
G LTF lactotransferrin increases expression ISO myricetin results in increased expression of LTF protein CTD PMID:24487097 NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234
JBrowse link
G LTN1 listerin E3 ubiquitin protein ligase 1 decreases expression EXP myricetin results in decreased expression of LTN1 protein CTD PMID:29698783 NCBI chr21:28,928,144...28,992,877
Ensembl chr21:28,928,144...28,992,956
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 multiple interactions ISO myricetin binds to and results in decreased activity of MAP2K1 protein; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein] CTD PMID:17693661 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656
JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 decreases phosphorylation ISO Myricetin decreases phosphorylation of Map3k7 protein in the heart RGD PMID:31885808 RGD:155791644 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
decreases activity
ISO myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]
myricetin results in decreased activity of MAPK1 protein
CTD PMID:17693661 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] CTD PMID:17693661 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK9 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein] CTD PMID:17693661 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase multiple interactions EXP myricetin inhibits the reaction [HGF protein results in increased phosphorylation of MET protein] CTD PMID:19244381 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377
JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions EXP myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein] CTD PMID:19804834 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression
multiple interactions
EXP myricetin results in decreased expression of MYC protein
[myricetin results in increased activity of SIRT1 protein] which results in decreased expression of MYC protein
CTD PMID:22245592 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 increases expression EXP myricetin results in increased expression of NFE2L2 protein CTD PMID:16799064 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 increases expression EXP myricetin results in increased expression of NME1 protein CTD PMID:29698783 NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428
JBrowse link
G OCLN occludin multiple interactions ISO myricetin inhibits the reaction [Indomethacin results in decreased expression of OCLN mRNA]; myricetin inhibits the reaction [Indomethacin results in decreased expression of OCLN protein] CTD PMID:33276066 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
JBrowse link
G PARG poly(ADP-ribose) glycohydrolase decreases activity EXP myricetin results in decreased activity of PARG protein CTD PMID:19840838 NCBI chr10:49,818,279...49,942,027
Ensembl chr10:49,818,279...49,970,203
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases cleavage
decreases activity
EXP myricetin results in increased cleavage of PARP1 protein
myricetin results in decreased activity of PARP1 protein
CTD PMID:15748703 PMID:17884996 PMID:29698783 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PIK3C2B phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta decreases expression EXP myricetin results in decreased expression of PIK3C2B protein CTD PMID:29698783 NCBI chr 1:204,422,633...204,494,805
Ensembl chr 1:204,422,628...204,494,805
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of PPARA protein] CTD PMID:25240712 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G PSCA prostate stem cell antigen decreases expression EXP myricetin results in decreased expression of PSCA mRNA CTD PMID:18331776 NCBI chr 8:142,670,297...142,682,725
Ensembl chr 8:142,670,308...142,682,725
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO
myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
CTD PMID:17944529 PMID:19804834 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein] CTD PMID:18958421 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G RPS12 ribosomal protein S12 decreases expression EXP myricetin results in decreased expression of RPS12 protein CTD PMID:29698783 NCBI chr 6:132,814,569...132,817,564
Ensembl chr 6:132,814,569...132,817,564
JBrowse link
G RPS6KA1 ribosomal protein S6 kinase A1 multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KA1 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KA1 protein] CTD PMID:17693661 NCBI chr 1:26,529,761...26,575,025
Ensembl chr 1:26,529,761...26,575,030
JBrowse link
G RPS6KB2 ribosomal protein S6 kinase B2 increases expression EXP myricetin results in increased expression of RPS6KB2 protein CTD PMID:29698783 NCBI chr11:67,428,494...67,435,401
Ensembl chr11:67,428,460...67,435,401
JBrowse link
G SIRT1 sirtuin 1 increases activity
increases expression
multiple interactions
EXP myricetin results in increased activity of SIRT1 protein
myricetin results in increased expression of SIRT1 protein
[myricetin results in increased activity of SIRT1 protein] which results in decreased expression of CTNNB1 protein; [myricetin results in increased activity of SIRT1 protein] which results in decreased expression of EGLN1 protein; [myricetin results in increased activity of SIRT1 protein] which results in decreased expression of MYC protein; [myricetin results in increased activity of SIRT1 protein] which results in increased expression of HIF1A protein
CTD PMID:22245592 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SLC2A1 solute carrier family 2 member 1 multiple interactions
decreases activity
EXP Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 protein]; myricetin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]
myricetin results in decreased activity of SLC2A1 protein
CTD PMID:14642735 PMID:36116563 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893
JBrowse link
G SLC2A2 solute carrier family 2 member 2 multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of SLC2A2 protein] CTD PMID:24923654 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO myricetin inhibits the reaction [Indomethacin results in increased phosphorylation of SRC protein] CTD PMID:33276066 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein] CTD PMID:25240712 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF2 protein] CTD PMID:25240712 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306
JBrowse link
G STAR steroidogenic acute regulatory protein multiple interactions ISO myricetin promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA] CTD PMID:28668616 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased expression of STAT3 mRNA]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein] CTD PMID:18995957 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
JBrowse link
G STK38L serine/threonine kinase 38 like decreases expression EXP myricetin results in decreased expression of STK38L protein CTD PMID:29698783 NCBI chr12:27,244,286...27,325,959
Ensembl chr12:27,243,968...27,325,959
JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of TGFB1 protein] CTD PMID:25240712 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TJP1 tight junction protein 1 multiple interactions ISO myricetin inhibits the reaction [Indomethacin results in decreased expression of TJP1 mRNA]; myricetin inhibits the reaction [Indomethacin results in decreased expression of TJP1 protein] CTD PMID:33276066 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915
JBrowse link
G TNF tumor necrosis factor multiple interactions EXP
ISO
myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]
myricetin inhibits the reaction [Ethanol results in increased expression of TNF protein]
CTD PMID:18958421 PMID:35156864 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TOP2A DNA topoisomerase II alpha decreases activity EXP myricetin results in decreased activity of TOP2A protein CTD PMID:16536579 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896
JBrowse link
G TP53 tumor protein p53 increases expression
multiple interactions
EXP myricetin analog results in increased expression of TP53 mRNA; myricetin analog results in increased expression of TP53 protein; myricetin results in increased expression of TP53 protein
myricetin affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of TP53 mRNA]
CTD PMID:32220605 PMID:32342131 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
G TP53I3 tumor protein p53 inducible protein 3 increases expression EXP myricetin results in increased expression of TP53I3 mRNA; myricetin results in increased expression of TP53I3 protein CTD PMID:19397994 NCBI chr 2:24,077,433...24,084,834
Ensembl chr 2:24,077,433...24,085,861
JBrowse link
G TP63 tumor protein p63 increases expression EXP myricetin results in increased expression of TP63 protein CTD PMID:19397994 NCBI chr 3:189,596,746...189,897,276
Ensembl chr 3:189,631,389...189,897,276
JBrowse link
G TP73 tumor protein p73 increases expression EXP myricetin results in increased expression of TP73 protein CTD PMID:19397994 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201
JBrowse link
G TXNRD1 thioredoxin reductase 1 decreases activity
multiple interactions
ISO myricetin results in decreased activity of TXNRD1 protein modified form
[Xanthine co-treated with XDH protein] promotes the reaction [myricetin results in decreased activity of TXNRD1 protein modified form]; Nitrogen inhibits the reaction [myricetin results in decreased activity of TXNRD1 protein modified form]
CTD PMID:16618767 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 decreases activity EXP myricetin results in decreased activity of UGT1A1 protein CTD PMID:35063619 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
JBrowse link
G UGT1A10 UDP glucuronosyltransferase family 1 member A10 decreases activity EXP myricetin results in decreased activity of UGT1A10 protein CTD PMID:35063619 NCBI chr 2:233,636,448...233,773,300
Ensembl chr 2:233,636,448...233,773,300
JBrowse link
G UGT1A3 UDP glucuronosyltransferase family 1 member A3 decreases activity EXP myricetin results in decreased activity of UGT1A3 protein CTD PMID:35063619 NCBI chr 2:233,729,042...233,773,300
Ensembl chr 2:233,729,042...233,773,300
JBrowse link
G UGT1A6 UDP glucuronosyltransferase family 1 member A6 decreases activity EXP myricetin results in decreased activity of UGT1A6 protein CTD PMID:35063619 NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300
JBrowse link
G UGT1A7 UDP glucuronosyltransferase family 1 member A7 decreases activity EXP myricetin results in decreased activity of UGT1A7 protein CTD PMID:35063619 NCBI chr 2:233,681,901...233,773,300
Ensembl chr 2:233,681,901...233,773,300
JBrowse link
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 decreases activity EXP myricetin results in decreased activity of UGT1A9 protein CTD PMID:35063619 NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300
JBrowse link
G UGT2B7 UDP glucuronosyltransferase family 2 member B7 decreases activity EXP myricetin results in decreased activity of UGT2B7 protein CTD PMID:35063619 NCBI chr 4:69,051,375...69,112,987
Ensembl chr 4:69,051,363...69,112,987
JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions ISO
EXP
myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of VEGFA protein]
myricetin inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]; myricetin promotes the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]
CTD PMID:20153296 PMID:25240712 PMID:26800359 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G XDH xanthine dehydrogenase multiple interactions ISO [Xanthine co-treated with XDH protein] promotes the reaction [myricetin results in decreased activity of TXNRD1 protein modified form]; myricetin inhibits the reaction [Ethanol results in increased activity of XDH protein] CTD PMID:16618767 PMID:35156864 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742
JBrowse link
(+)-dihydromyricetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK1 protein] CTD PMID:21871475 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK3 protein] CTD PMID:21871475 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G PDGFB platelet derived growth factor subunit B multiple interactions ISO ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK1 protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK3 protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PDGFRB protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PLCG1 protein] CTD PMID:21871475 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
JBrowse link
G PDGFRB platelet derived growth factor receptor beta multiple interactions ISO ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PDGFRB protein] CTD PMID:21871475 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
JBrowse link
G PLCG1 phospholipase C gamma 1 multiple interactions ISO ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PLCG1 protein] CTD PMID:21871475 NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801
JBrowse link
G SPHK1 sphingosine kinase 1 decreases expression
decreases activity
EXP ampelopsin results in decreased expression of SPHK1 protein
ampelopsin results in decreased activity of SPHK1 protein
CTD PMID:22251058 NCBI chr17:76,383,204...76,387,855
Ensembl chr17:76,376,584...76,387,860
JBrowse link
myricitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTA2 actin alpha 2, smooth muscle multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:25656916 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339
JBrowse link
G ALPL alkaline phosphatase, biomineralization associated multiple interactions ISO
EXP
myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ALPL mRNA] CTD PMID:25130202 NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410
JBrowse link
G APOE apolipoprotein E multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in decreased activity of CAT protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased activity of CASP3 protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CCL2 protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CRP protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of ICAM1 protein] CTD PMID:23639522 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein] CTD PMID:23639522 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:23639522 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein multiple interactions ISO
EXP
myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BGLAP mRNA] CTD PMID:25130202 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G CASP3 caspase 3 multiple interactions EXP
ISO
myricitrin inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]
myricitrin inhibits the reaction [APOE gene mutant form results in increased activity of CASP3 protein]
CTD PMID:23639522 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CAT catalase multiple interactions EXP
ISO
myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]
myricitrin inhibits the reaction [APOE gene mutant form results in decreased activity of CAT protein]
CTD PMID:23639522 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CCL2 protein] CTD PMID:23639522 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions ISO
EXP
myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of COL1A1 mRNA] CTD PMID:25130202 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G CRP C-reactive protein multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CRP protein] CTD PMID:23639522 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein] CTD PMID:25656916 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein] CTD PMID:25656916 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of GPX1 protein] CTD PMID:23639522 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of ICAM1 protein] CTD PMID:23639522 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IL6 interleukin 6 multiple interactions EXP
ISO
myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 protein] CTD PMID:25130202 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] CTD PMID:23639522 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] CTD PMID:23639522 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:23639522 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of NOS3 protein] CTD PMID:23639522 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions ISO myricitrin promotes the reaction [Carbon Tetrachloride results in increased expression of PCNA protein] CTD PMID:25656916 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of PPARG mRNA] CTD PMID:25130202 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein] CTD PMID:25656916 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein] CTD PMID:25656916 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TNF tumor necrosis factor multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein] CTD PMID:25656916 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFSF11 TNF superfamily member 11 multiple interactions ISO
EXP
myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFSF11 protein] CTD PMID:25130202 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013
JBrowse link
G TP53 tumor protein p53 multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein] CTD PMID:23639522 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    role 25956
      chemical role 24245
        antioxidant 17490
          myricetin 128
            3',5,7-trihydroxy-3,4',5'-trimethoxyflavone 0
            3',5-dihydroxy-3,4',5',7-tetramethoxyflavone 0
            3,3',4',5'-tetramethylmyricetin 0
            3,3',5'-trimethylmyricetin 0
            5,7,3',5'-tetrahydroxy-3,4'-dimethyoxyflavone 0
            7,3',5'-trimethylmyricetin 0
            7-O-methylmyricetin 0
            combretol 0
            dihydromyricetin + 6
            laricitrin 0
            myricetin 3-O-[(6-O-trans-4-coumaroyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] 0
            myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] + 0
            myricetin 3-O-beta-D-galactopyranoside 0
            myricetin 3-O-beta-L-galactopyranoside 0
            myricetin O-glucoside + 0
            myricetin O-glucuronide + 0
            myricetin-3-O-arabinofuranoside 0
            myricetin-3-O-beta-D-xylopyranoside 0
            myricitrin + 27
            syringetin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26040
    subatomic particle 26015
      composite particle 26015
        hadron 26015
          baryon 26015
            nucleon 26015
              atomic nucleus 26015
                atom 26015
                  main group element atom 25840
                    p-block element atom 25840
                      carbon group element atom 25437
                        carbon atom 25395
                          organic molecular entity 25395
                            organic molecule 25223
                              organic cyclic compound 24277
                                organic heterocyclic compound 22320
                                  oxacycle 20023
                                    benzopyran 12740
                                      1-benzopyran 12476
                                        flavonoid 7601
                                          anthoxanthin 4701
                                            flavones 4701
                                              hydroxyflavone 4680
                                                flavonols 4566
                                                  7-hydroxyflavonol 4540
                                                    myricetin 128
                                                      3',5,7-trihydroxy-3,4',5'-trimethoxyflavone 0
                                                      3',5-dihydroxy-3,4',5',7-tetramethoxyflavone 0
                                                      3,3',4',5'-tetramethylmyricetin 0
                                                      3,3',5'-trimethylmyricetin 0
                                                      5,7,3',5'-tetrahydroxy-3,4'-dimethyoxyflavone 0
                                                      7,3',5'-trimethylmyricetin 0
                                                      7-O-methylmyricetin 0
                                                      combretol 0
                                                      dihydromyricetin + 6
                                                      laricitrin 0
                                                      myricetin 3-O-[(6-O-trans-4-coumaroyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] 0
                                                      myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] + 0
                                                      myricetin 3-O-beta-D-galactopyranoside 0
                                                      myricetin 3-O-beta-L-galactopyranoside 0
                                                      myricetin O-glucoside + 0
                                                      myricetin O-glucuronide + 0
                                                      myricetin-3-O-arabinofuranoside 0
                                                      myricetin-3-O-beta-D-xylopyranoside 0
                                                      myricitrin + 27
                                                      syringetin 0
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