| 3738 | Sp1 | Sp1 transcription factor | ENCODES a protein that exhibits double-stranded DNA binding; histone acetyltransferase binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; INVOLVED IN cellular response to estrogen stimulus; cellular response to insulin stimulus; cellular response to wortmannin; PARTICIPA TES IN phosphatidylinositol 3-kinase-Akt signaling pathway; forkhead class A signaling pathway; hypoxia inducible factor pathway; ASSOCIATED WITH Carotid Artery Injuries; Colorectal Neoplasms (ortholog); Disease Progression (ortholog); FOUND IN chromatin; nucleus; protein-DNA complex; INTERACTS WITH 1,2-dimethylhydrazine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,2',4,4'-Tetrabromodiphenyl ether | 7 | 135419864 | 135450513 | Rat | 577 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 11334 | Sp1 | trans-acting transcription factor 1 | Enables DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II and response to hydroperoxide. Acts upstream of or within several processes, including embryo development; hemopoiesis; and mRNA transcription by RNA polymerase II. Located in chromatin and nucleus. Is expressed in several structures, including central nervous system; early conceptus; epithelium; eye; and genitourinary system. Orthologous to human SP1 (Sp1 transcription factor). [provided by Alliance of Genome Resources, Jul 2025] | 15 | 102314751 | 102344839 | Mouse | 582 | symbol , old_gene_name , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 732035 | SP1 | Sp1 transcription factor | The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodelin g. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014] | 12 | 53380176 | 53416446 | Human | 586 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8854816 | Sp1 | Sp1 transcription factor | ENCODES a protein that exhibits bHLH transcription factor binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); DNA binding (ortholog); INVOLVED IN cellular response to estrogen stimulus (ortholog); cellular response to insulin stimulus (ortholog); cellular response to wortmannin (ortholog); PARTICIPATES IN forkhead class A signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH Carotid Artery Injuries (ortholog); Colorectal Neoplasms (ortholog); Disease Progression (ortholog); FOUND IN chromatin (ortholog); euchromatin (ortholog); nucleoplasm (ortholog) | NW_004955458 | 644435 | 677360 | Chinchilla | 141 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12017134 | SP1 | Sp1 transcription factor | ENCODES a protein that exhibits bHLH transcription factor binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN cellular response to estrogen stimulus (ortholog); cellular response to insulin stimulus (ortholog); cellu lar response to wortmannin (ortholog); PARTICIPATES IN forkhead class A signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH Carotid Artery Injuries (ortholog); Colorectal Neoplasms (ortholog); Disease Progression (ortholog); FOUND IN protein-DNA complex (ortholog) | 12 | 35338492 | 35374462 | Bonobo | 128 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12296991 | SP1 | Sp1 transcription factor | ENCODES a protein that exhibits bHLH transcription factor binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN cellular response to estrogen stimulus (ortholog); cellular response to insulin stimulus (ortholog); cellu lar response to wortmannin (ortholog); PARTICIPATES IN forkhead class A signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH Carotid Artery Injuries (ortholog); Colorectal Neoplasms (ortholog); Disease Progression (ortholog); FOUND IN protein-DNA complex (ortholog); INTERACTS WITH anthra[1,9-cd]pyrazol-6(2H)-one; bisphenol A; sodium chloride | 27 | 1802587 | 1861187 | Dog | 132 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12479750 | Sp1 | Sp1 transcription factor | ENCODES a protein that exhibits bHLH transcription factor binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN cellular response to estrogen stimulus (ortholog); cellular response to insulin stimulus (ortholog); cellu lar response to wortmannin (ortholog); PARTICIPATES IN forkhead class A signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH Carotid Artery Injuries (ortholog); Colorectal Neoplasms (ortholog); Disease Progression (ortholog); FOUND IN protein-DNA complex (ortholog) | NW_004936512 | 10655116 | 10693025 | Squirrel | 127 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13968836 | SP1 | Sp1 transcription factor | ENCODES a protein that exhibits bHLH transcription factor binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN cellular response to estrogen stimulus (ortholog); cellular response to insulin stimulus (ortholog); cellu lar response to wortmannin (ortholog); PARTICIPATES IN forkhead class A signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH Carotid Artery Injuries (ortholog); Colorectal Neoplasms (ortholog); Disease Progression (ortholog); FOUND IN protein-DNA complex (ortholog) | | | | Pig | 128 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14388528 | Sp1 | | | | | | Fly | | symbol | gene, null |
| 18586318 | SP1 | Sp1 transcription factor | ENCODES a protein that exhibits bHLH transcription factor binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN cellular response to estrogen stimulus (ortholog); cellular response to insulin stimulus (ortholog); cellu lar response to wortmannin (ortholog); PARTICIPATES IN forkhead class A signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH Carotid Artery Injuries (ortholog); Colorectal Neoplasms (ortholog); Disease Progression (ortholog); FOUND IN protein-DNA complex (ortholog) | | | | Green Monkey | 127 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18903575 | Sp1 | Sp1 transcription factor | ENCODES a protein that exhibits bHLH transcription factor binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to estrogen stimulus (ortholog); cellular r esponse to insulin stimulus (ortholog); cellular response to wortmannin (ortholog); PARTICIPATES IN forkhead class A signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH Carotid Artery Injuries (ortholog); Colorectal Neoplasms (ortholog); Disease Progression (ortholog); FOUND IN chromatin (ortholog); euchromatin (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 138 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 155243031 | sp1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625960091 | Sp1 | Sp1 transcription factor | ENCODES a protein that exhibits bHLH transcription factor binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); DNA binding (ortholog); INVOLVED IN cellular response to estrogen stimulus (ortholog); cellular response to insulin stimulus (ortholog); cellular response to wortmannin (ortholog); PARTICIPATES IN forkhead class A signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH Carotid Artery Injuries (ortholog); Colorectal Neoplasms (ortholog); Disease Progression (ortholog); FOUND IN chromatin (ortholog); euchromatin (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 141 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 155233699 | sp1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155241068 | sp1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1342724 | DAND5 | DAN domain BMP antagonist family member 5 | This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystin e knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq, Jul 2008] | 19 | 12969576 | 12974760 | Human | 68 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 731483 | Hnrnpu | heterogeneous nuclear ribonucleoprotein U | Enables several functions, including RNA polymerase II C-terminal domain binding activity; lncRNA binding activity; and promoter-specific chromatin binding activity. Involved in several processes, including RNA localization to chromatin; cellular response to leukemia inhibitory factor; and regulatio n of gene expression. Acts upstream of or within with a positive effect on mRNA metabolic process. Acts upstream of or within several processes, including brown fat cell differentiation; cardiac muscle cell development; and erythrocyte differentiation. Located in inactive sex chromosome and nucleus. Part of ribonucleoprotein complex. Is expressed in several structures, including branchial arch; future brain; limb primordium; tail bud; and unsegmented mesenchyme. Used to study developmental and epileptic encephalopathy 54. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 54. Orthologous to human HNRNPU (heterogeneous nuclear ribonucleoprotein U). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 178148673 | 178170063 | Mouse | 463 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1551996 | P2ry13 | purinergic receptor P2Y, G-protein coupled 13 | Predicted to enable G protein-coupled purinergic nucleotide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in endoplasmic reticulum. Is expressed in immune system; intestine; male reproductive gland or organ; and skin. Orthologous to human P2RY13 (purinergic receptor P2Y13). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 59115313 | 59118303 | Mouse | 81 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1352538 | PSG1 | pregnancy specific beta-1-glycoprotein 1 | The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).[supplied by OMIM, Oct 2009] | 19 | 42866464 | 42879713 | Human | 37 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1603165 | PRSS55 | serine protease 55 | This gene encodes a member of a group of membrane-anchored chymotrypsin (S1)-like serine proteases. The enocoded protein is primarily expressed in the Leydig and Sertoli cells of the testis and may be involved in male fertility. Alternate splicing results in multiple transcript variants. [provided b y RefSeq, Sep 2010] | 8 | 10525532 | 10554166 | Human | 40 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1346991 | SYPL1 | synaptophysin like 1 | Predicted to be involved in chemical synaptic transmission. Located in extracellular exosome. [provided by Alliance of Genome Resources, Jul 2025] | 7 | 106090505 | 106112576 | Human | 92 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 69288 | St14 | ST14 transmembrane serine protease matriptase | ENCODES a protein that exhibits serine-type peptidase activity; serine-type endopeptidase activity (ortholog); INVOLVED IN protein catabolic process; epithelial cell morphogenesis involved in placental branching (ortholog); keratinocyte differentiation (ortholog); ASSOCIATED WITH autosomal recessive congenital ichthyosis 11 (ortholog); Breast Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN basolateral plasma membrane; extracellular space; external side of plasma membrane (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 37798994 | 37839881 | Rat | 182 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 733374 | ST14 | ST14 transmembrane serine protease matriptase | The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte g rowth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008] | 11 | 130159782 | 130210362 | Human | 210 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 733375 | St14 | suppression of tumorigenicity 14 (colon carcinoma) | Enables serine-type endopeptidase activity. Involved in proteolysis. Acts upstream of or within epithelial cell morphogenesis involved in placental branching and neural tube closure. Located in external side of plasma membrane and extracellular space. Is expressed in several structures, including al imentary system; brain; early conceptus; genitourinary system; and sensory organ. Used to study Sjogren's syndrome. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 11. Orthologous to human ST14 (ST14 transmembrane serine protease matriptase). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 30999886 | 31043138 | Mouse | 293 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 18926990 | LOC101710452 | transcription factor Sp1 pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 18900352 | LOC101723137 | transcription factor Sp1 pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 8735812 | LOC102017150 | transcription factor Sp1 pseudogene | | NW_004955431 | 16457241 | 16462926 | Chinchilla | | name | gene, pseudo, MODEL [RefSeq] |
| 15037009 | CRSP5 | cofactor required for Sp1 transcriptional activation subunit 5 | | | | | Human | | old_gene_name , name | gene, protein-coding |
| 1319465 | TLE1 | TLE family member 1, transcriptional corepressor | Enables DNA-binding transcription factor binding activity; identical protein binding activity; and transcription corepressor activity. Involved in negative regulation of anoikis; negative regulation of signal transduction; and regulation of gene expression. Located in cytosol and nucleoplasm. Part o f beta-catenin-TCF complex. [provided by Alliance of Genome Resources, Jul 2025] | 9 | 81583683 | 81689547 | Human | 159 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1359186 | Olr1469 | olfactory receptor Olr1469 | ENCODES a protein that exhibits G protein-coupled olfactory receptor activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH ammonium chloride; antirheumatic drug ( ortholog); methotrexate (ortholog) | 10 | 58523553 | 58524497 | Rat | 21 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
| 39128668 | Gm57553 | predicted gene, 57553 | | 1 | 92929596 | 92932762 | Mouse | | old_gene_name | gene, pseudo, MODEL [RefSeq] |
| 1344641 | KLF13 | KLF transcription factor 13 | KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008] | 15 | 31326835 | 31435665 | Human | 163 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1314308 | KLF16 | KLF transcription factor 16 | Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within G protein-coupled dopamine receptor signaling pathway. Predicted to be located in chromatin. [provided by Alliance of G enome Resources, Jul 2025] | 19 | 1852399 | 1876536 | Human | 93 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 12275137 | MED23 | mediator complex subunit 23 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN positive regulation of gene expression (ortholog); positive regulation of T cell extravasation (ortholog); protein ubiquitination (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH autosomal recessive intellectual developmental disorder 18 (ortholog); Fraser syndrome 3 (ortholog); genetic disease (ortholog); FOUND IN ubiquitin ligase complex (ortholog) | 12 | 195638 | 240741 | Dog | 26 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 1317214 | RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interact ing protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] | 8 | 100257067 | 100336204 | Human | 116 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
| 1343127 | MED14 | mediator complex subunit 14 | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. [provided by RefSeq, Jul 2008] | X | 40648305 | 40736159 | Human | 106 | old_gene_name , description , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1322408 | MED17 | mediator complex subunit 17 | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq, Jul 2008] | 11 | 93784282 | 93814963 | Human | 125 | old_gene_name , description | gene, protein-coding, REVIEWED [RefSeq] |
| 1322409 | Med17 | mediator complex subunit 17 | Predicted to enable nuclear thyroid hormone receptor binding activity and transcription coactivator activity. Predicted to contribute to ubiquitin protein ligase activity. Acts upstream of or within somatic stem cell population maintenance. Part of mediator complex. Is expressed in genitourinary sys tem and limb mesenchyme. Human ortholog(s) of this gene implicated in infantile cerebral and cerebellar atrophy with postnatal progressive microcephaly. Orthologous to human MED17 (mediator complex subunit 17). [provided by Alliance of Genome Resources, Apr 2025] | 9 | 15171647 | 15194576 | Mouse | 99 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1307671 | Med23 | mediator complex subunit 23 | ENCODES a protein that exhibits ubiquitin protein ligase activity; INVOLVED IN protein ubiquitination; positive regulation of gene expression (ortholog); positive regulation of T cell extravasation (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH autosomal recessi ve intellectual developmental disorder 18 (ortholog); Fraser syndrome 3 (ortholog); genetic disease (ortholog); FOUND IN ubiquitin ligase complex; mediator complex (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; allethrin; atrazine | 1 | 22309613 | 22377745 | Rat | 85 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1316995 | MED23 | mediator complex subunit 23 | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012] | 6 | 131573966 | 131628313 | Human | 134 | old_gene_name , description , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1316996 | Med23 | mediator complex subunit 23 | Predicted to contribute to ubiquitin protein ligase activity. Acts upstream of or within positive regulation of T cell extravasation and positive regulation of gene expression. Part of mediator complex. Is expressed in several structures, including genitourinary system; tibialis anterior; and tongue . Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 18. Orthologous to human MED23 (mediator complex subunit 23). [provided by Alliance of Genome Resources, Apr 2025] | 10 | 24745889 | 24789358 | Mouse | 158 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1348876 | MED24 | mediator complex subunit 24 | This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene exp ression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | 17 | 40019104 | 40054408 | Human | 91 | old_gene_name , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1352604 | MED26 | mediator complex subunit 26 | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq, Jul 2008] | 19 | 16574919 | 16628204 | Human | 88 | old_gene_name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1557558 | Med26 | mediator complex subunit 26 | Predicted to enable transcription coregulator activity. Predicted to be involved in positive regulation of gene expression and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Is expressed in sev eral structures, including central nervous system; limb; retina; and tongue. Orthologous to human MED26 (mediator complex subunit 26). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 73248402 | 73302154 | Mouse | 90 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1349942 | MED27 | mediator complex subunit 27 | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011] | 9 | 131860112 | 132079867 | Human | 131 | old_gene_name , description | gene, protein-coding, REVIEWED [RefSeq] |
| 1623965 | Med27 | mediator complex subunit 27 | Predicted to enable transcription coactivator activity. Predicted to contribute to ubiquitin protein ligase activity. Acts upstream of or within somatic stem cell population maintenance. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of core mediator complex; me diator complex; and ubiquitin ligase complex. Is expressed in genitourinary system and tibialis anterior. Orthologous to human MED27 (mediator complex subunit 27). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 29236822 | 29414802 | Mouse | 109 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 14147364 | MED27 | mediator complex subunit 27 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN protein ubiquitination (ortholog); regulation of transcription by RNA polymerase II (ortholog); stem cell population maintenance (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED W ITH genetic disease (ortholog); intellectual disability (ortholog); NEURODEVELOPMENTAL DISORDER WITH SPASTICITY, CATARACTS, AND CEREBELLAR HYPOPLASIA (ortholog); FOUND IN ubiquitin ligase complex (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 28 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1321085 | MED7 | mediator complex subunit 7 | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] | 5 | 157137424 | 157142865 | Human | 87 | old_gene_name , description | gene, protein-coding, REVIEWED [RefSeq] |
| 1321086 | Med7 | mediator complex subunit 7 | Predicted to enable transcription coregulator activity. Predicted to contribute to ubiquitin protein ligase activity. Acts upstream of or within somatic stem cell population maintenance. Part of mediator complex. Is expressed in cerebral cortex; genitourinary system; and tibialis anterior. Orthologo us to human MED7 (mediator complex subunit 7). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 46327742 | 46333548 | Mouse | 94 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 14114826 | MED7 | mediator complex subunit 7 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN protein ubiquitination (ortholog); regulation of transcription by RNA polymerase II (ortholog); stem cell population maintenance (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; FOUND IN ubi quitin ligase complex (ortholog) | | | | Pig | 31 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1617593 | Med14 | mediator complex subunit 14 | Predicted to enable transcription coactivator activity. Acts upstream of or within somatic stem cell population maintenance. Part of mediator complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human MED14 (mediator complex subunit 14). [provided by Alliance of Genome Resources, Jul 2025] | X | 12541607 | 12628813 | Mouse | 107 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1311120 | Med17 | mediator complex subunit 17 | ENCODES a protein that exhibits ubiquitin protein ligase activity; nuclear thyroid hormone receptor binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN protein ubiquitination; positive regulation of DNA-templated transcription (ortholog); positive regulation of transcripti on by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH endometriosis (ortholog); genetic disease (ortholog); infantile cerebral and cerebellar atrophy with postnatal progressive microcephaly (ortholog); FOUND IN ubiquitin ligase complex; mediator complex (ortholog); nucleus (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A | 8 | 20382995 | 20401993 | Rat | 85 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 6494481 | Med7 | mediator complex subunit 7 | ENCODES a protein that exhibits ubiquitin protein ligase activity; INVOLVED IN protein ubiquitination; regulation of transcription by RNA polymerase II (ortholog); stem cell population maintenance (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; FOUND IN ubiquitin ligase complex; mediator complex (ortholog); nuclear body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; tetrachloromethane | 10 | 31343613 | 31359192 | Rat | 70 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1309237 | Tle1 | TLE family member 1, transcriptional corepressor | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor binding (ortholog); identical protein binding (ortholog); INVOLVED IN negative regulation of anoikis (ortholog); negative regulation of canonical NF-kappaB signal transduction (ortholog); negative regulati on of DNA-templated transcription (ortholog); FOUND IN beta-catenin-TCF complex (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 5 | 90898182 | 90982118 | Rat | 143 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 8903401 | Tle1 | TLE family member 1, transcriptional corepressor | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor binding (ortholog); identical protein binding (ortholog); INVOLVED IN negative regulation of anoikis (ortholog); negative regulation of canonical NF-kappaB signal transduction (ortholog); negative regulati on of DNA-templated transcription (ortholog); FOUND IN beta-catenin-TCF complex (ortholog); cytosol (ortholog); nucleoplasm (ortholog) | NW_004955530 | 1936936 | 2028803 | Chinchilla | 40 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14079557 | TLE1 | TLE family member 1, transcriptional corepressor | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); regulation of DNA-templated transcription (ortholog); regulation of transcription by RNA polymerase II (ortholog); FOUND IN beta-catenin-TCF complex (inferr ed); cytosol (inferred); nucleoplasm (inferred); INTERACTS WITH deoxynivalenol; graphene oxide | | | | Pig | 46 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 1306665 | Tle2 | TLE family member 2, transcriptional corepressor | ENCODES a protein that exhibits transcription corepressor activity (ortholog); INVOLVED IN negative regulation of canonical Wnt signaling pathway (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH lymphopenia (ortholog); neutropenia (ortholog); FOUND IN nuclea r body (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 7 | 8769815 | 8789493 | Rat | 117 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1315408 | TLE2 | TLE family member 2, transcriptional corepressor | Enables transcription corepressor activity. Involved in negative regulation of DNA-templated transcription and negative regulation of canonical Wnt signaling pathway. Located in focal adhesion and nuclear body. [provided by Alliance of Genome Resources, Jul 2025] | 19 | 2997644 | 3047635 | Human | 125 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 8868414 | Tle2 | TLE family member 2, transcriptional corepressor | ENCODES a protein that exhibits transcription corepressor activity (ortholog); INVOLVED IN negative regulation of canonical Wnt signaling pathway (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH lymphopenia (ortholog); neutropenia (ortholog); FOUND IN nuclea r body (ortholog) | NW_004955495 | 5347496 | 5366743 | Chinchilla | 7 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11838356 | TLE2 | TLE family member 2, transcriptional corepressor | ENCODES a protein that exhibits transcription corepressor activity (inferred); INVOLVED IN negative regulation of canonical Wnt signaling pathway (inferred); negative regulation of DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); ASSOCIATED WITH lymphopen ia (ortholog); neutropenia (ortholog); FOUND IN nuclear body (inferred); nucleus (inferred); transcription regulator complex (inferred) | 19 | 2023018 | 2055317 | Bonobo | 16 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12387971 | TLE2 | TLE family member 2, transcriptional corepressor | ENCODES a protein that exhibits transcription corepressor activity (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of canonical Wnt signaling pathway (inferred); negative regulation of DNA-templated transcription (inferred); ASSOCIATED WITH lymphopenia (ortholog); neutropenia (ortholog); FOUND IN nuclear body (inferred); nucleus (inferred) | 20 | 56138654 | 56157625 | Dog | 23 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12625586 | Tle2 | TLE family member 2, transcriptional corepressor | ENCODES a protein that exhibits transcription corepressor activity (inferred); INVOLVED IN negative regulation of canonical Wnt signaling pathway (inferred); negative regulation of DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); ASSOCIATED WITH lymphopen ia (ortholog); neutropenia (ortholog); FOUND IN nuclear body (inferred); nucleus (inferred); transcription regulator complex (inferred) | NW_004936588 | 1718263 | 1734408 | Squirrel | 16 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14023138 | TLE2 | TLE family member 2, transcriptional corepressor | ENCODES a protein that exhibits transcription corepressor activity (inferred); INVOLVED IN negative regulation of canonical Wnt signaling pathway (inferred); negative regulation of DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); ASSOCIATED WITH lymphopen ia (ortholog); neutropenia (ortholog); FOUND IN nuclear body (inferred); nucleus (inferred); INTERACTS WITH deoxynivalenol; graphene oxide | | | | Pig | 18 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18908492 | Tle2 | TLE family member 2, transcriptional corepressor | ENCODES a protein that exhibits transcription corepressor activity (inferred); INVOLVED IN negative regulation of canonical Wnt signaling pathway (inferred); negative regulation of DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); ASSOCIATED WITH lymphopen ia (ortholog); neutropenia (ortholog); FOUND IN nuclear body (ortholog) | | | | Naked Mole-Rat | 13 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 620292 | Tle3 | TLE family member 3, transcriptional corepressor | ENCODES a protein that exhibits transcription coactivator activity (ortholog); transcription corepressor activity (ortholog); INVOLVED IN regulation of DNA-templated transcription; fat cell differentiation (ortholog); negative regulation of canonical Wnt signaling pathway (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); Breast Neoplasms (ortholog); rheumatoid arthritis (ortholog); FOUND IN nucleus; beta-catenin-TCF complex (ortholog); chromatin (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; all-trans-retinoic acid | 8 | 70753182 | 70799080 | Rat | 157 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1351900 | TLE3 | TLE family member 3, transcriptional corepressor | This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013] | 15 | 70047790 | 70097917 | Human | 148 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
| 8905832 | Tle3 | TLE family member 3, transcriptional corepressor | ENCODES a protein that exhibits transcription coactivator activity (ortholog); transcription corepressor activity (ortholog); INVOLVED IN fat cell differentiation (ortholog); negative regulation of canonical Wnt signaling pathway (ortholog); negative regulation of cold-induced thermogenesis (ortholo g); ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); Breast Neoplasms (ortholog); rheumatoid arthritis (ortholog); FOUND IN beta-catenin-TCF complex (ortholog); chromatin (ortholog); nucleoplasm (ortholog) | NW_004955450 | 6604915 | 6645305 | Chinchilla | 22 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12001853 | TLE3 | TLE family member 3, transcriptional corepressor | ENCODES a protein that exhibits transcription coactivator activity (inferred); transcription corepressor activity (inferred); INVOLVED IN regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); Breast Neoplasms (ortholog); rheumatoid art hritis (ortholog); FOUND IN beta-catenin-TCF complex (inferred); chromatin (inferred); nucleoplasm (inferred) | 15 | 49000145 | 49050246 | Bonobo | 31 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12333865 | TLE3 | TLE family member 3, transcriptional corepressor | ENCODES a protein that exhibits transcription coactivator activity (inferred); transcription corepressor activity (inferred); INVOLVED IN regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); Breast Neoplasms (ortholog); rheumatoid art hritis (ortholog); FOUND IN beta-catenin-TCF complex (inferred); chromatin (inferred); nucleoplasm (inferred) | 30 | 33803719 | 33895204 | Dog | 31 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12460045 | Tle3 | TLE family member 3, transcriptional corepressor | ENCODES a protein that exhibits transcription coactivator activity (inferred); transcription corepressor activity (inferred); INVOLVED IN regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); Breast Neoplasms (ortholog); rheumatoid art hritis (ortholog); FOUND IN beta-catenin-TCF complex (inferred); chromatin (inferred); nucleoplasm (inferred) | NW_004936471 | 29682313 | 29730229 | Squirrel | 31 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 13918675 | TLE3 | TLE family member 3, transcriptional corepressor | ENCODES a protein that exhibits transcription coactivator activity (inferred); transcription corepressor activity (inferred); INVOLVED IN regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); Breast Neoplasms (ortholog); rheumatoid art hritis (ortholog); FOUND IN beta-catenin-TCF complex (inferred); chromatin (inferred); nucleoplasm (inferred) | | | | Pig | 31 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18933693 | Tle3 | TLE family member 3, transcriptional corepressor | ENCODES a protein that exhibits transcription coactivator activity (ortholog); INVOLVED IN fat cell differentiation (ortholog); negative regulation of cold-induced thermogenesis (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (or tholog); Breast Neoplasms (ortholog); rheumatoid arthritis (ortholog); FOUND IN beta-catenin-TCF complex (ortholog); chromatin (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 28 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 3868 | Tle4 | TLE family member 4, transcriptional corepressor | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of DNA-templated transcription (ortholog); neg ative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); Experimental Mammary Neoplasms (ortholog); FOUND IN beta-catenin-TCF complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-ethoxyethanol; 2-methoxyethanol | 1 | 221086250 | 221222826 | Rat | 144 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 733230 | TLE4 | TLE family member 4, transcriptional corepressor | Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within Wnt signaling pathway; cellular response to leukemia inhibi tory factor; and negative regulation of DNA-templated transcription. Located in nucleoplasm. Part of beta-catenin-TCF complex. [provided by Alliance of Genome Resources, Apr 2025] | 9 | 79571965 | 79726882 | Human | 139 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 12410233 | TLE4 | TLE family member 4, transcriptional corepressor | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor binding (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polyme rase II (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); Experimental Mammary Neoplasms (ortholog); FOUND IN beta-catenin-TCF complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 1 | 79126261 | 79268052 | Dog | 32 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12613336 | Tle4 | TLE family member 4, transcriptional corepressor | ENCODES a protein that exhibits chromatin binding (inferred); DNA-binding transcription factor binding (inferred); transcription corepressor activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of DNA-templated transcription (ortholog); neg ative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); Experimental Mammary Neoplasms (ortholog); FOUND IN beta-catenin-TCF complex (inferred); nucleoplasm (inferred); nucleus (inferred) | NW_004936632 | 3077594 | 3213763 | Squirrel | 34 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14143734 | TLE4 | TLE family member 4, transcriptional corepressor | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor binding (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polyme rase II (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); Experimental Mammary Neoplasms (ortholog); FOUND IN beta-catenin-TCF complex (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 32 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 1343822 | TLE6 | TLE family member 6, subcortical maternal complex member | This gene encodes a member of the Groucho/ transducin-like Enhancer of split family of transcriptional co-repressors. The encoded protein is a component of the mammalian subcortical maternal complex, which is required for preimplantation development. In mouse, knock out of this gene results in cleav age-stage embryonic arrest resulting from defective cytoplasmic F-actin meshwork formation and asymmetric cell division. In human, an allelic variant in this gene is associated with preimplantation embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] | 19 | 2977401 | 2995179 | Human | 112 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
| 1561530 | Tle6 | TLE family member 6, subcortical maternal complex member | ENCODES a protein that exhibits structural constituent of cytoplasmic lattice (ortholog); INVOLVED IN actin filament organization (ortholog); embryonic process involved in female pregnancy (ortholog); endoplasmic reticulum localization (ortholog); ASSOCIATED WITH Oocyte/Zygote/Embryo Maturation Arre st 15 (ortholog); FOUND IN cell cortex (ortholog); cytoplasm (ortholog); cytoplasmic lattice (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; bisphenol A | 7 | 8757846 | 8769405 | Rat | 103 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12008395 | TLE6 | TLE family member 6, subcortical maternal complex member | ENCODES a protein that exhibits structural constituent of cytoplasmic lattice (inferred); transcription corepressor activity (inferred); INVOLVED IN actin filament organization (ortholog); endoplasmic reticulum localization (ortholog); epigenetic programming in the zygotic pronuclei (ortholog); ASSO CIATED WITH Oocyte/Zygote/Embryo Maturation Arrest 15 (ortholog); FOUND IN cell cortex (ortholog); sperm midpiece (ortholog) | 19 | 2003011 | 2020577 | Bonobo | 47 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12173689 | TLE6 | TLE family member 6, subcortical maternal complex member | ENCODES a protein that exhibits structural constituent of cytoplasmic lattice (inferred); INVOLVED IN actin filament organization (ortholog); embryonic process involved in female pregnancy (ortholog); endoplasmic reticulum localization (ortholog); ASSOCIATED WITH Oocyte/Zygote/Embryo Maturation Arre st 15 (ortholog); FOUND IN cell cortex (ortholog); cytoplasmic lattice (ortholog); protein-containing complex (ortholog) | 20 | 56159045 | 56169740 | Dog | 41 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12567732 | Tle6 | TLE family member 6, subcortical maternal complex member | ENCODES a protein that exhibits structural constituent of cytoplasmic lattice (ortholog); INVOLVED IN actin filament organization (ortholog); embryonic process involved in female pregnancy (ortholog); endoplasmic reticulum localization (ortholog); ASSOCIATED WITH Oocyte/Zygote/Embryo Maturation Arre st 15 (ortholog); FOUND IN cell cortex (ortholog); cytoplasm (ortholog); cytoplasmic lattice (ortholog) | NW_004936588 | 1708013 | 1717956 | Squirrel | 39 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 13867230 | TLE6 | TLE family member 6, subcortical maternal complex member | ENCODES a protein that exhibits structural constituent of cytoplasmic lattice (inferred); INVOLVED IN actin filament organization (ortholog); embryonic process involved in female pregnancy (ortholog); endoplasmic reticulum localization (ortholog); ASSOCIATED WITH Oocyte/Zygote/Embryo Maturation Arre st 15 (ortholog); FOUND IN cell cortex (ortholog); cytoplasmic lattice (ortholog); protein-containing complex (ortholog) | | | | Pig | 41 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18913829 | Tle6 | TLE family member 6, subcortical maternal complex member | ENCODES a protein that exhibits structural constituent of cytoplasmic lattice (inferred); transcription corepressor activity (inferred); INVOLVED IN actin filament organization (ortholog); embryonic process involved in female pregnancy (ortholog); endoplasmic reticulum localization (ortholog); ASSOC IATED WITH Oocyte/Zygote/Embryo Maturation Arrest 15 (ortholog); FOUND IN cell cortex (ortholog); cytoplasmic lattice (ortholog); protein-containing complex (ortholog) | | | | Naked Mole-Rat | 46 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 1605687 | DROSHA | drosha ribonuclease III | This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRN A) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. [provided by RefSeq, Sep 2016] | 5 | 31400494 | 31532093 | Human | 170 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
| 1313558 | MIS18BP1 | MIS18 binding protein 1 | Predicted to enable DNA binding activity. Predicted to be involved in cell division. Predicted to be located in nucleoplasm. Predicted to be part of CENP-A recruiting complex. Predicted to be active in chromosome, centromeric region. [provided by Alliance of Genome Resources, Jul 2025] | 14 | 45203190 | 45253202 | Human | 108 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 12260971 | MED17 | mediator complex subunit 17 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); protein ubiquitination (ortholog); regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcript ion pathway; ASSOCIATED WITH endometriosis (ortholog); genetic disease (ortholog); infantile cerebral and cerebellar atrophy with postnatal progressive microcephaly (ortholog); FOUND IN ubiquitin ligase complex (ortholog) | 21 | 6967304 | 6990542 | Dog | 36 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12097109 | MED26 | mediator complex subunit 26 | ENCODES a protein that exhibits transcription coregulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription pathway; FOUND IN mediator complex (inferred); membrane (inf erred); nucleoplasm (inferred) | 20 | 45923034 | 45977118 | Dog | 26 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12069668 | MED27 | mediator complex subunit 27 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN protein ubiquitination (ortholog); regulation of transcription by RNA polymerase II (ortholog); stem cell population maintenance (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED W ITH genetic disease (ortholog); intellectual disability (ortholog); NEURODEVELOPMENTAL DISORDER WITH SPASTICITY, CATARACTS, AND CEREBELLAR HYPOPLASIA (ortholog); FOUND IN ubiquitin ligase complex (ortholog) | 9 | 52136652 | 52331676 | Dog | 27 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12256784 | MED7 | mediator complex subunit 7 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN protein ubiquitination (ortholog); regulation of transcription by RNA polymerase II (ortholog); stem cell population maintenance (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; FOUND IN ubi quitin ligase complex (ortholog) | 4 | 52998748 | 53004063 | Dog | 31 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 12389071 | MED14 | mediator complex subunit 14 | ENCODES a protein that exhibits transcription coactivator activity (inferred); transcription coregulator activity (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); stem cell population maintenance (ortholog); PARTICIPATES IN cortisol signaling pathway; RNA polymerase II transcription pathway; ASSOCIATED WITH endometriosis (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN mediator complex (inferred); nucleus (inferred) | X | 35125270 | 35191260 | Dog | 28 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 1564993 | Med27 | mediator complex subunit 27 | ENCODES a protein that exhibits ubiquitin protein ligase activity; transcription coactivator activity (ortholog); INVOLVED IN protein ubiquitination; regulation of transcription by RNA polymerase II (ortholog); stem cell population maintenance (ortholog); PARTICIPATES IN RNA polymerase II transcript ion pathway; ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); NEURODEVELOPMENTAL DISORDER WITH SPASTICITY, CATARACTS, AND CEREBELLAR HYPOPLASIA (ortholog); FOUND IN ubiquitin ligase complex; mediator complex (ortholog); nucleolus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; C60 fullerene | 3 | 33027240 | 33201240 | Rat | 90 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 6481424 | PIRAT1 | PU.1 (SPI1) induced regulator of S100A8 and S100A9 alarmin transcription 1 | | 2 | 37826247 | 37875863 | Human | | old_gene_name | gene, ncrna, VALIDATED [RefSeq] |
| 1560170 | Med14 | mediator complex subunit 14 | ENCODES a protein that exhibits transcription coactivator activity (ortholog); transcription coregulator activity (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); positive regulation of transc ription initiation by RNA polymerase II (ortholog); PARTICIPATES IN cortisol signaling pathway; RNA polymerase II transcription pathway; ASSOCIATED WITH endometriosis (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN mediator complex (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | X | 12709406 | 12800642 | Rat | 93 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1348100 | SP100 | SP100 nuclear antigen | This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011] | 2 | 230416201 | 230545606 | Human | 209 | symbol , old_gene_name , COSMIC , name , description , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1359550 | Sp100 | SP100 nuclear antigen | ENCODES a protein that exhibits chromo shadow domain binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN DNA damage response, signal transduction by p53 class mediator (ortholog); maintenance of protein location (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN cytoplasm (ortholog); Mre11 complex (ortholog); nuclear body (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; acetamide; bisphenol A | 9 | 93758975 | 93825068 | Rat | 182 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1558598 | Sp100 | nuclear antigen Sp100 | Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; chromo shadow domain binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including innate immune response; regulation of DNA-tem plated transcription; and regulation of signal transduction. Predicted to be located in cytoplasm and nuclear lumen. Predicted to be part of Mre11 complex. Is expressed in eye; olfactory placode; and otic pit. Orthologous to human SP100 (SP100 nuclear antigen). [provided by Alliance of Genome Resources, Apr 2025] | 1 | 85577683 | 85637719 | Mouse | 167 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8968083 | Sp100 | SP100 nuclear antigen | ENCODES a protein that exhibits chromo shadow domain binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN DNA damage response, signal transduction by p53 class mediator (ortholog); maintenance of protein location (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN cytoplasm (ortholog); Mre11 complex (ortholog); nuclear body (ortholog) | NW_004955453 | 4774739 | 4856238 | Chinchilla | 64 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11894058 | SP100 | SP100 nuclear antigen | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein homodimerization activity (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcri ption (ortholog); negative regulation of viral transcription (ortholog); response to cytokine (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN nuclear periphery (ortholog); nucleolus (ortholog) | 2B | 117673152 | 117799911 | Bonobo | 67 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12164006 | SP100 | SP100 nuclear antigen | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein homodimerization activity (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcri ption (ortholog); negative regulation of viral transcription (ortholog); response to cytokine (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN nuclear periphery (ortholog) | 25 | 42538428 | 42635825 | Dog | 68 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12496548 | Sp100 | SP100 nuclear antigen | ENCODES a protein that exhibits chromo shadow domain binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN DNA damage response, signal transduction by p53 class mediator (ortholog); maintenance of protein location (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN cytoplasm (ortholog); Mre11 complex (ortholog); nuclear body (ortholog) | NW_004936525 | 6136343 | 6231051 | Squirrel | 64 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18407301 | SP100 | SP100 nuclear antigen | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein homodimerization activity (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcri ption (ortholog); negative regulation of viral transcription (ortholog); response to cytokine (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN nuclear periphery (ortholog) | | | | Green Monkey | 67 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18934803 | Sp100 | SP100 nuclear antigen | ENCODES a protein that exhibits chromo shadow domain binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); INVOLVED IN DNA damage response, signal transduction by p53 class mediator (ortholog); maintenance of pr otein location (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN cytoplasm (ortholog); Mre11 complex (ortholog); nuclear body (ortholog) | | | | Naked Mole-Rat | 71 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 1310173 | Sp110 | SP110 nuclear body protein | ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN positive regulation of apoptotic process (ortholog); response to bacterium (ortholog); ASSOCIATED WITH genetic disease (ortholog); hepatic venoocclusive disease with immunodeficiency (ortholog); tuberculosis (ortholog); FOUND IN nuc leoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,3',5,5'-tetrabromobisphenol A | 9 | 93648574 | 93673476 | Rat | 103 | symbol , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1320919 | SP110 | SP110 nuclear body protein | The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Jul 2008] | 2 | 230165186 | 230225636 | Human | 167 | symbol , old_gene_name , COSMIC , name , description , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1320920 | Sp110 | Sp110 nuclear body protein | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Acts upstream of or within positive regulation of apoptotic process and response to bacterium. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in central nervous system; early conceptus; genitourinary system; and thymus primordium. Human ortholog(s) of this gene implicated in hepatic venoocclusive disease with immunodeficiency and tuberculosis. Orthologous to human SP110 (SP110 nuclear body protein). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 85498462 | 85538571 | Mouse | 103 | symbol , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8933403 | Sp110 | SP110 nuclear body protein | INVOLVED IN positive regulation of apoptotic process (ortholog); response to bacterium (ortholog); ASSOCIATED WITH genetic disease (ortholog); hepatic venoocclusive disease with immunodeficiency (ortholog); tuberculosis (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog) | NW_004955453 | 4915541 | 4939438 | Chinchilla | 10 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11987063 | SP110 | SP110 nuclear body protein | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN positive regulation of apoptotic process (ortholog); response to bacterium (ortholog); ASSOCIATED WITH genetic disease ( ortholog); hepatic venoocclusive disease with immunodeficiency (ortholog); tuberculosis (ortholog); FOUND IN cytoplasm (inferred); nuclear lumen (inferred); nucleolus (inferred) | 2B | 117417230 | 117472246 | Bonobo | 22 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12174811 | SP110 | SP110 nuclear body protein | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN positive regulation of apoptotic process (ortholog); response to bacterium (ortholog); ASSOCIATED WITH genetic disease (ortholog); hepatic venoocclusive disease with immunod eficiency (ortholog); tuberculosis (ortholog); FOUND IN nuclear lumen (inferred); nucleoplasm (inferred); nucleus (inferred) | 25 | 42418565 | 42459098 | Dog | 19 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12644178 | Sp110 | SP110 nuclear body protein | INVOLVED IN positive regulation of apoptotic process (ortholog); response to bacterium (ortholog); ASSOCIATED WITH genetic disease (ortholog); hepatic venoocclusive disease with immunodeficiency (ortholog); tuberculosis (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog) | NW_004936525 | 6317004 | 6336413 | Squirrel | 10 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 14050487 | SP110 | SP110 nuclear body protein | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN positive regulation of apoptotic process (ortholog); response to bacterium (ortholog); ASSOCIATED WITH genetic disease (ortholog); hepatic venoocclusive disease with immunod eficiency (ortholog); tuberculosis (ortholog); FOUND IN nuclear lumen (inferred); nucleoplasm (inferred); nucleus (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 20 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18913352 | Sp110 | SP110 nuclear body protein | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN positive regulation of apoptotic process (ortholog); response to bacterium (ortholog); ASSOCIATED WITH genetic disease (ortholog); hepatic venoocclusi ve disease with immunodeficiency (ortholog); tuberculosis (ortholog); FOUND IN nucleoplasm (ortholog) | | | | Naked Mole-Rat | 14 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 598151353 | sp110 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 598153120 | sp110 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 1306355 | Sp140 | SP140 nuclear body protein | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH B-Cell Chronic Lymphocytic Leukemia (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; 4,4 '-diaminodiphenylmethane; acetamide | 9 | 93672536 | 93722596 | Rat | 45 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1314926 | SP140 | SP140 nuclear body protein | This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal a utoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016] | 2 | 230186151 | 230316571 | Human | 53 | symbol , old_gene_name , COSMIC , name , description , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1621872 | Sp140 | Sp140 nuclear body protein | Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in fibrillar center and mitochondrion. Predicted to be active in nucleus. Orthologous to human ... (more) an style='font-weight:700;'>SP140 (SP140 nuclear body protein) and SP140L (SP140 nuclear body protein like). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 85515212 | 85572761 | Mouse | 58 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9007740 | Sp140 | SP140 nuclear body protein | ASSOCIATED WITH B-Cell Chronic Lymphocytic Leukemia (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN nucleus (ortholog) | NW_004955453 | 4864812 | 4911699 | Chinchilla | 5 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11796198 | SP140 | SP140 nuclear body protein | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN defense response (inferred); regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH B-Cell Chronic Lymphocytic Leukemia (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (inferred); nucleolus (inferred); nucleus (inferred) | 2B | 117477923 | 117565367 | Bonobo | 16 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12129514 | SP140 | SP140 nuclear body protein | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN defense response (inferred); ASSOCIATED WITH B-Cell Chronic Lymphocytic Leukemia (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (inferred); nuclear lumen (inferred); nucleolus (inferred) | 25 | 42459013 | 42527141 | Dog | 16 | symbol , old_gene_name , name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12608640 | Sp140 | SP140 nuclear body protein | ASSOCIATED WITH B-Cell Chronic Lymphocytic Leukemia (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN nucleus (ortholog) | NW_004936525 | 6239566 | 6301657 | Squirrel | 5 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13971513 | SP140 | SP140 nuclear body protein | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH B-Cell Chronic Lymphocytic Leukemia (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN nuclear lumen (inferred); nucleus (inferred) | | | | Pig | 14 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18356858 | SP140 | SP140 nuclear body protein | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN defense response (inferred); regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH B-Cell Chronic Lymphocytic Leukemia (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (inferred); nucleolus (inferred); nucleus (inferred) | | | | Green Monkey | 16 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625969684 | Sp140 | SP140 nuclear body protein | ASSOCIATED WITH B-Cell Chronic Lymphocytic Leukemia (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN nucleus (ortholog) | | | | Black Rat | 5 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14369464 | SP1029 | | | | | | Fly | | symbol | gene, null |
| 1604252 | SP140L | SP140 nuclear body protein like | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025] | 2 | 230327193 | 230403732 | Human | 54 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 11952986 | SP140L | SP140 nuclear body protein like | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN defense response (inferred); regulation of transcription by RNA polymerase II (inferred); FOUND IN cytoplasm (inferred); nuclear lumen (inferred); nucleolus (inferred) | 2B | 117578707 | 117663997 | Bonobo | 12 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18744253 | SP140L | SP140 nuclear body protein like | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN defense response (inferred); regulation of transcription by RNA polymerase II (inferred); FOUND IN cytoplasm (inferred); nucleolus (inferred); nucleus (inferred) | | | | Green Monkey | 11 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 626179952 | sp110.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626188287 | sp110.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 1621186 | Sp140l1 | Sp140 nuclear body protein like 1 | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in fibrillar center and mitochondrion. Predicted to be active in nucleus. [provided by Alliance of Genome R esources, Apr 2025] | 1 | 85065860 | 85088016 | Mouse | 5 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1613879 | Sp140l2 | Sp140 nuclear body protein like 2 | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in fibrillar center and mitochondrion. Predicted to be active in nucleus. [provided by Alliance of Genome R esources, Apr 2025] | 1 | 85219007 | 85260602 | Mouse | 4 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 617252031 | Sp100-rs | uncharacterized LOC546065 | | | | | Mouse | | symbol , PhenoGen | gene, protein-coding |
| 1608152 | Sp100-rs1 | nuclear antigen Sp100, related sequence 1 | | | | | Mouse | | symbol , PhenoGen , name | gene, protein-coding |
| 39128921 | Sp110-ps1 | Sp110 nuclear body protein, pseudogene 1 | Predicted to be located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025] | 1 | 85250516 | 85254756 | Mouse | | symbol , old_gene_name , PhenoGen , name | gene, pseudo, MODEL [RefSeq] |
| 2306402 | Sp110-ps2 | Sp110 nuclear body protein, pseudogene 2 | Predicted to be located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025] | 5 | 137718613 | 137720254 | Mouse | | symbol , PhenoGen , name | gene, pseudo, INFERRED [RefSeq] |
| 620153 | Acrv1 | acrosomal vesicle protein 1 | ASSOCIATED WITH prostate cancer (ortholog); FOUND IN acrosomal vesicle (ortholog); INTERACTS WITH ammonium chloride; bisphenol A; cypermethrin | 8 | 44593246 | 44598823 | Rat | 27 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1606758 | CCDC54 | coiled-coil domain containing 54 | INTERACTS WITH benzene-1,2,4-triol; benzo[a]pyrene; valproic acid | 3 | 107377439 | 107378635 | Human | 10 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 11131 | Ppia | peptidylprolyl isomerase A | Enables integrin binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in platelet aggregation. Acts upstream of or within neuron differentiation. Located in extracellular space. Is expressed in several structures, including early conceptus; gonad; hemolymphoid system gland; li ver; and skeletal muscle. Human ortholog(s) of this gene implicated in cholangiocarcinoma and human immunodeficiency virus infectious disease. Orthologous to human PPIA (peptidylprolyl isomerase A). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 6365867 | 6369817 | Mouse | 334 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 620154 | Spa17 | sperm autoantigenic protein 17 | INVOLVED IN binding of sperm to zona pellucida (inferred); single fertilization (inferred); ASSOCIATED WITH Merkel cell carcinoma (ortholog); Neoplasm Metastasis (ortholog); FOUND IN cilium (ortholog); cytoplasm (ortholog); external side of plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachl orodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene | 8 | 45496175 | 45507262 | Rat | 120 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 731295 | Spa17 | sperm autoantigenic protein 17 | Predicted to enable calmodulin binding activity. Predicted to act upstream of or within binding activity of sperm to zona pellucida. Located in several cellular components, including external side of plasma membrane; neuron projection; and sperm flagellum. Is expressed in several structures, includi ng brain; gonad; heart; hemolymphoid system gland; and lung. Orthologous to human SPA17 (sperm autoantigenic protein 17). [provided by Alliance of Genome Resources, Apr 2025] | 9 | 37514590 | 37525018 | Mouse | 125 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1353517 | SPA17 | sperm autoantigenic protein 17 | This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq, Jan 2009] | 11 | 124673904 | 124697518 | Human | 122 | old_gene_name , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1605641 | GPBP1L1 | GC-rich promoter binding protein 1 like 1 | Predicted to enable DNA binding activity and RNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025] | 1 | 45627304 | 45688110 | Human | 64 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 620372 | Hnrnpu | heterogeneous nuclear ribonucleoprotein U | ENCODES a protein that exhibits poly(G) binding; promoter-specific chromatin binding; ribonucleoprotein complex binding; INVOLVED IN cellular response to dexamethasone stimulus; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity; positive regulation of gene expression; PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); colorectal cancer (ortholog); developmental and epileptic encephalopathy 1 (ortholog); FOUND IN ribonucleoprotein complex; catalytic step 2 spliceosome (ortholog); cell surface (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 13 | 92609791 | 92618580 | Rat | 384 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 13913586 | LOC100517129 | nuclear body protein SP140-like protein | ENCODES a protein that exhibits chromo shadow domain binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); INVOLVED IN DNA damage response, signal transduction by p53 class mediator (ortholog); maintenance of pr otein location (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN cytoplasm (ortholog); Mre11 complex (ortholog); nuclear body (ortholog) | | | | Pig | 70 | old_gene_name , name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18916764 | LOC101725789 | nuclear body protein SP140 | | | | | Naked Mole-Rat | | old_gene_name , name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18342031 | LOC103218031 | sp110 nuclear body protein | INVOLVED IN positive regulation of apoptotic process (ortholog); response to bacterium (ortholog); ASSOCIATED WITH genetic disease (ortholog); hepatic venoocclusive disease with immunodeficiency (ortholog); tuberculosis (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog) | | | | Green Monkey | 10 | old_gene_name , name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1351174 | MED1 | mediator complex subunit 1 | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008] | 17 | 39404285 | 39451263 | Human | 341 | description , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1602708 | P2RY13 | purinergic receptor P2Y13 | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. [provided by RefSeq, Se p 2008] | 3 | 151326312 | 151329549 | Human | 67 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 69112 | PMP22 | peripheral myelin protein 22 | This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas synd rome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] | 17 | 15229779 | 15265326 | Human | 722 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1354000 | P2RY12 | purinergic receptor P2Y12 | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013] | 3 | 151336843 | 151384753 | Human | 172 | old_gene_name , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1351516 | SPA17P1 | sperm autoantigenic protein 17 pseudogene 1 | | 10 | 75382217 | 75382910 | Human | | old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 1620810 | Ccdc54 | coiled-coil domain containing 54 | Orthologous to human CCDC54 (coiled-coil domain containing 54). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 50410222 | 50411517 | Mouse | 13 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1323516 | CDADC1 | cytidine and dCMP deaminase domain containing 1 | Enables several functions, including cytidine deaminase activity; importin-alpha family protein binding activity; and protein homodimerization activity. Involved in DNA cytosine deamination and cytidine deamination. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 202 5] | 13 | 49247925 | 49293485 | Human | 90 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1323517 | Cdadc1 | cytidine and dCMP deaminase domain containing 1 | Predicted to enable several functions, including deaminase activity; importin-alpha family protein binding activity; and protein homodimerization activity. Predicted to be involved in DNA cytosine deamination and cytidine deamination. Predicted to be located in nucleus. Predicted to be active in cyt oplasm. Orthologous to human CDADC1 (cytidine and dCMP deaminase domain containing 1). [provided by Alliance of Genome Resources, Apr 2025] | 14 | 59796837 | 59835433 | Mouse | 93 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1346196 | CTNNBL1 | catenin beta like 1 | The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, an d binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013] | 20 | 37694030 | 37872118 | Human | 116 | old_gene_name , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1557138 | Ctnnbl1 | catenin, beta like 1 | Predicted to enable enzyme binding activity. Predicted to be involved in positive regulation of apoptotic process and somatic diversification of immunoglobulins. Predicted to act upstream of or within apoptotic process. Predicted to be located in centrosome; cytosol; and nucleoplasm. Predicted to be part of Prp19 complex and spliceosomal complex. Is expressed in cerebral cortex ventricular layer; embryo; limb; and limb mesenchyme. Human ortholog(s) of this gene implicated in colorectal cancer; immunodeficiency 99; and morbid obesity. Orthologous to human CTNNBL1 (catenin beta like 1). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 157579321 | 157733823 | Mouse | 113 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1606759 | GARIN1B | golgi associated RAB2 interactor 1B | Predicted to be involved in acrosome assembly and acrosome reaction. Predicted to be located in Golgi apparatus. [provided by Alliance of Genome Resources, Jul 2025] | 7 | 128709061 | 128731743 | Human | 50 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1623697 | Garin1b | golgi associated RAB2 interactor 1B | Involved in acrosome assembly and acrosome reaction. Located in Golgi apparatus. Orthologous to human GARIN1B (golgi associated RAB2 interactor 1B). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 29313468 | 29336021 | Mouse | 66 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1354416 | RFX4 | regulatory factor X4 | This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with its elf as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011] | 12 | 106583004 | 106762803 | Human | 112 | old_gene_name , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1557863 | Rfx4 | regulatory factor X, 4 (influences HLA class II expression) | Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including central nervous system development; negative regulation of smoothen ed signaling pathway; and regulation of gene expression. Located in nucleus. Is expressed in several structures, including central nervous system; eye; future brain; genitourinary system; and liver. Orthologous to human RFX4 (regulatory factor X4). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 84591895 | 84742402 | Mouse | 131 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1351808 | SPATA16 | spermatogenesis associated 16 | This gene encodes a testis-specific protein that belongs to the tetratricopeptide repeat-like superfamily. The encoded protein localizes to the Golgi apparatus and may play a role in spermatogenesis. [provided by RefSeq, May 2010] | 3 | 172889357 | 173141235 | Human | 95 | old_gene_name , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1557391 | Spata16 | spermatogenesis associated 16 | Involved in spermatid development. Acts upstream of or within spermatogenesis. Predicted to be located in acrosomal vesicle. Predicted to be active in Golgi apparatus. Used to study male infertility. Human ortholog(s) of this gene implicated in spermatogenic failure 6. Orthologous to human SPATA16 ( spermatogenesis associated 16). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 26691769 | 27037398 | Mouse | 45 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1317981 | SPATA9 | spermatogenesis associated 9 | Predicted to be involved in cell differentiation and spermatogenesis. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025] | 5 | 95652181 | 95732102 | Human | 18 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1605320 | TTC29 | tetratricopeptide repeat domain 29 | Involved in cilium movement and cilium organization. Located in sperm flagellum. Implicated in spermatogenic failure 42. [provided by Alliance of Genome Resources, Jul 2025] | 4 | 146706617 | 146945864 | Human | 63 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1602453 | WDR87 | WD repeat domain 87 | INTERACTS WITH (+)-catechin; arsane; arsenic atom | 19 | 37884823 | 37906697 | Human | 10 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 16565457 | AL359704.1 | SP100 nuclear antigen (SP100) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 1615317 | Gm7609 | predicted pseudogene 7609 | This gene is one of several duplicated genes in a repeat cluster in the homogeneously staining region (HSR) of chromosome 1. It is an Sp100-rs gene copy, which arose by duplication following the fusion of the Csprs (component of Sp1 100-rs) gene and the 5' part of the Sp100 (nuclear antigen Sp100) gene. The coding sequence of this gene is intact compared to that of the Csprs gene, and therefore NCBI represents this as a protein-coding gene. However, it is also possible to interpret this fusion gene as a pseudogene of the Sp100 gene. It is unknown if this gene produces a protein in vivo. [provided by RefSeq, Mar 2011] | 1 | 85177313 | 85193119 | Mouse | 12 | old_gene_name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 731794 | SP4 | Sp4 transcription factor | The protein encoded by this gene is a transcription factor that can bind to the GC promoter region of a variety of genes, including those of the photoreceptor signal transduction system. The encoded protein binds to the same sites in promoter CpG islands as does the transcription factor SP1 'font-weight:700;'>SP1, although its expression is much more restricted compared to that of SP1. This gene may be involved in bipolar disorder and schizophrenia. [provided by RefSeq, May 2016] | 7 | 21428083 | 21514822 | Human | 128 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 736536 | Ces2c | carboxylesterase 2C | This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and ch olesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. The transcription of this gene is regulated by several factors including HNF-4alpha (hepatocyte nuclear factor-4alpha), Sp1 (specificity protein 1), Sp3 and USF1 (upstream stimulatory factor 1). The expression and activity of this gene is age-related but independent of growth hormone level. This gene is clustered with several family members including a few of pseudogenes and Ces5 on chromosome 8.[provided by RefSeq, Jun 2010] | 8 | 105573700 | 105581115 | Mouse | 109 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1321957 | Csprs | component of Sp100-rs | Predicted to be located in nucleus. Orthologous to human SP100 (SP100 nuclear antigen). [provided by Alliance of Genome Resources, Apr 2025] | | | | Mouse | 59 | name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 30307096 | HULC | hepatocellular carcinoma up-regulated long non-coding RNA | This gene produces a long RNA that was discovered as upregulated in hepatocellular carcinoma and is associated with cancer progression. Expression of this transcript is regulated by microRNAs and at the transcriptional level by Sp1 family factors. The transcript may regulate gene expression by functioning as a competing RNA for microRNAs. [provided by RefSeq, Dec 2017] | 6 | 8652269 | 8653856 | Human | 14 | description | gene, ncrna, VALIDATED [RefSeq] |
| 1352833 | IER3IP1 | immediate early response 3 interacting protein 1 | This gene encodes a small protein that is localized to the endoplasmic reticulum (ER) and may play a role in the ER stress response by mediating cell differentiation and apoptosis. Transcription of this gene is regulated by tumor necrosis factor alpha and specificity protein 1 (Sp1 ght:700;'>Sp1). Mutations in this gene may play a role in microcephaly, epilepsy, and diabetes syndrome (MEDS), and a pseudogene of this gene is located on the long arm of chromosome 12. [provided by RefSeq, Dec 2011] | 18 | 47152834 | 47176364 | Human | 128 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1318282 | KIF12 | kinesin family member 12 | This gene encodes a member of the kinesin superfamily of microtubule-associated molecular motors with functions related to the microtubule cytosekelton. Members of this superfamily play important roles in intracellular transport and cell division. A similar protein in mouse functions in the beta cel l antioxidant signaling cascade, acting as a scaffold for the transcription factor specificity protein 1 (Sp1). Mice that lack this gene exhibit beta cell oxidative stress resulting in hypoinsulinemic glucose intolerance. [provided by RefSeq, Jul 2016] | 9 | 114091638 | 114099292 | Human | 115 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1605424 | KLF11 | KLF transcription factor 11 | The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabet es of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010] | 2 | 10043550 | 10054836 | Human | 223 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1320615 | POGZ | pogo transposable element derived with ZNF domain | The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system. Alternatively spliced transcript variants e ncoding distinct isoforms have been observed. [provided by RefSeq, Aug 2010] | 1 | 151402724 | 151459494 | Human | 390 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1319619 | SCARF1 | scavenger receptor class F member 1 | The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac-LDL), and it may be involved in atherogenesis. This gene is regulated by the tran scription factors ZNF444/EZF-2 and SP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013] | 17 | 1633858 | 1645732 | Human | 70 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1319818 | SP3 | Sp3 transcription factor | This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transa ctivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13. [provided by RefSeq, Feb 2010] | 2 | 173900775 | 173965702 | Human | 188 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1319819 | Sp3 | trans-acting transcription factor 3 | This gene product belongs to a family of Sp1 related transcription factors, which regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivatio n domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses transcription of numerous genes. Alternative splicing results in transcript variants encoding different isoforms, and one variant initiates translation from a non-AUG (AUA) codon. [provided by RefSeq, Jul 2008] | 2 | 72766774 | 72810790 | Mouse | 257 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 69146 | TCF20 | transcription factor 20 | This gene encodes a transcription factor that recognizes the platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 promoter. The encoded protein is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1 font-weight:700;'>SP1. Mutations in this gene are associated with autism spectrum disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] | 22 | 42160013 | 42343537 | Human | 198 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1310830 | Csprs | component of Sp100-rs | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); FOUND IN membrane (inferred); INTERACTS WITH bisphenol A | 9 | 93613834 | 93620964 | Rat | 9 | name | gene, protein-coding, MODEL [RefSeq] |
| 1615333 | Gm7592 | predicted gene 7592 | Orthologous to human GPR148 (G protein-coupled receptor 148). [provided by Alliance of Genome Resources, Apr 2025] | 1 | 85304553 | 85483402 | Mouse | 14 | old_gene_name , ensembl_full_name | gene, protein-coding, VALIDATED [RefSeq] |
| 39131243 | LOC100039029 | component of Sp100-rs-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 39130765 | LOC101055663 | component of Sp100-rs-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 39130037 | LOC102636558 | component of Sp100-rs-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 18591544 | LOC103215961 | sperm surface protein Sp17 | FOUND IN cilium (ortholog); cytoplasm (ortholog); external side of plasma membrane (ortholog) | | | | Green Monkey | 5 | name | gene, protein-coding, MODEL [RefSeq] |
| 626048750 | LOC116898564 | component of Sp100-rs-like | | | | | Black Rat | | name | gene, protein-coding, MODEL [RefSeq] |
| 39128312 | LOC671917 | component of Sp100-rs-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 39128541 | LOC100040974 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, pseudo, MODEL [RefSeq] |
| 39128672 | LOC100041057 | nuclear body protein SP140-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 39130807 | LOC101055672 | nuclear body protein SP140-like | | | | | Mouse | | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 39129982 | LOC102633548 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, pseudo, MODEL [RefSeq] |
| 39129423 | LOC102633783 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, protein-coding, VALIDATED [RefSeq] |
| 39131042 | LOC102638047 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, protein-coding, VALIDATED [RefSeq] |
| 39129236 | LOC105242404 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 39129504 | LOC115486430 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, pseudo, MODEL [RefSeq] |
| 626045188 | LOC116899580 | sp110 nuclear body protein-like | | | | | Black Rat | | name | gene, protein-coding, MODEL [RefSeq] |
| 39128655 | LOC118567365 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, pseudo, MODEL [RefSeq] |
| 39128803 | LOC118568473 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 39128521 | LOC118568475 | nuclear body protein SP140-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 329344826 | LOC129393151 | sperm surface protein Sp17-like | | | | | Bonobo | | name | gene, pseudo, MODEL [RefSeq] |
| 598131552 | LOC140712613 | sp110 nuclear body protein-like | | | | | Green Monkey | | name | gene, protein-coding, MODEL [RefSeq] |
| 39129995 | LOC677525 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 16570165 | AC010149.2 | Novel Sp100-like protein pseudogene | | | | | Human | | name | gene, unitary_pseudogene |
| 16553350 | AC009950.1 | novel transcript, antisense to SP110 | | | | | Human | | name | gene, lncrna |
| 16556220 | AC010149.1 | novel transcript, antisense to SP100 | | | | | Human | | name | gene, lncrna |
| 39128985 | LOC100041034 | Sp110 nuclear body protein pseudogene | | | | | Mouse | | name | gene, pseudo, VALIDATED [RefSeq] |
| 39128863 | LOC664787 | Sp110 nuclear body protein pseudogene | | | | | Mouse | | name | gene, pseudo, VALIDATED [RefSeq] |
| 39130349 | LOC100041708 | nuclear body protein SP140-like protein | | | | | Mouse | | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12151562 | LOC100686622 | nuclear body protein SP140-like protein | FOUND IN nucleus (inferred) | 25 | 42643992 | 42684365 | Dog | 1 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 8706280 | LOC102027482 | nuclear body protein SP140-like protein | | NW_004955453 | 4735334 | 4878501 | Chinchilla | | name | gene, protein-coding, MODEL [RefSeq] |
| 39128445 | LOC108167387 | nuclear body protein SP140-like protein | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 626047982 | LOC116898246 | nuclear body protein SP140-like protein | | | | | Black Rat | | name | gene, protein-coding, MODEL [RefSeq] |
| 39129412 | LOC118568468 | nuclear body protein SP140-like protein | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 124777461 | LOC120883710 | nuclear body protein SP140-like protein | | | | | Squirrel | | name | gene, protein-coding, MODEL [RefSeq] |
| 69360 | Sec11a | SEC11 homolog A, signal peptidase complex subunit | ENCODES a protein that exhibits serine-type endopeptidase activity (ortholog); INVOLVED IN signal peptide processing (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); signal peptidase complex (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 17alph a-ethynylestradiol; 2,3,7,8-Tetrachlorodibenzofuran | 1 | 144290680 | 144318658 | Rat | 91 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1344783 | SEC11A | SEC11 homolog A, signal peptidase complex subunit | This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signal peptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis. Alternative splicing results in multiple transcript variants. A related pseud ogene has been identified on chromosome 8. [provided by RefSeq, Dec 2012] | 15 | 84669544 | 84716139 | Human | 88 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
| 1553779 | Sec11a | SEC11 homolog A, signal peptidase complex subunit | Predicted to enable serine-type endopeptidase activity. Predicted to be involved in signal peptide processing. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of signal peptidase complex. Is expressed in several structures, including alimentary system; cranium; genito urinary system; integumental system; and nervous system. Orthologous to human SEC11A (SEC11 homolog A, signal peptidase complex subunit). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 80565125 | 80597295 | Mouse | 86 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 12232499 | SEC11A | SEC11 homolog A, signal peptidase complex subunit | ENCODES a protein that exhibits serine-type endopeptidase activity (ortholog); INVOLVED IN signal peptide processing (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN signal peptidase complex | 3 | 53940644 | 53980422 | Dog | 26 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2308286 | Gm2619 | predicted gene 2619 | | 1 | 85291128 | 85305100 | Mouse | | old_gene_name | gene, pseudo, VALIDATED [RefSeq] |
| 10029803 | Gm38510 | predicted gene, 38510 | | 1 | 85132922 | 85286736 | Mouse | | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 8895466 | Spa17 | sperm autoantigenic protein 17 | ASSOCIATED WITH Merkel cell carcinoma (ortholog); Neoplasm Metastasis (ortholog); FOUND IN cilium (ortholog); cytoplasm (ortholog); external side of plasma membrane (ortholog) | NW_004955412 | 25741369 | 25753681 | Chinchilla | 18 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12047230 | SPA17 | sperm autoantigenic protein 17 | ENCODES a protein that exhibits calmodulin binding (inferred); INVOLVED IN binding of sperm to zona pellucida (inferred); single fertilization (inferred); ASSOCIATED WITH Merkel cell carcinoma (ortholog); Neoplasm Metastasis (ortholog); FOUND IN cilium (inferred); cytoplasm (inferred); external side of plasma membrane (inferred) | 11 | 119501604 | 119526103 | Bonobo | 22 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12253975 | SPA17 | sperm autoantigenic protein 17 | INVOLVED IN binding of sperm to zona pellucida (inferred); single fertilization (inferred); ASSOCIATED WITH Merkel cell carcinoma (ortholog); Neoplasm Metastasis (ortholog); FOUND IN cilium (inferred); cytoplasm (inferred); external side of plasma membrane (inferred) | 5 | 9719222 | 9731521 | Dog | 22 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14231822 | SPA17 | sperm autoantigenic protein 17 | INVOLVED IN binding of sperm to zona pellucida (inferred); single fertilization (inferred); ASSOCIATED WITH Merkel cell carcinoma (ortholog); Neoplasm Metastasis (ortholog); FOUND IN cilium (inferred); cytoplasm (inferred); external side of plasma membrane (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 23 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18931701 | Spa17 | sperm autoantigenic protein 17 | ENCODES a protein that exhibits calmodulin binding (inferred); INVOLVED IN binding of sperm to zona pellucida (inferred); single fertilization (inferred); ASSOCIATED WITH Merkel cell carcinoma (ortholog); Neoplasm Metastasis (ortholog); FOUND IN cilium (ortholog); external side of plasma membrane (o rtholog); motile cilium (ortholog) | | | | Naked Mole-Rat | 20 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 40899994 | SPA17 | sperm autoantigenic protein 17 | ENCODES a protein that exhibits calmodulin binding (inferred); INVOLVED IN binding of sperm to zona pellucida (inferred); single fertilization (inferred); ASSOCIATED WITH Merkel cell carcinoma (ortholog); Neoplasm Metastasis (ortholog); FOUND IN cilium (inferred); cytoplasm (inferred); external side of plasma membrane (inferred) | | | | Green Monkey | 22 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 124934302 | Spa17 | sperm autoantigenic protein 17 | ENCODES a protein that exhibits calmodulin binding (inferred); INVOLVED IN binding of sperm to zona pellucida (inferred); single fertilization (inferred); ASSOCIATED WITH Merkel cell carcinoma (ortholog); Neoplasm Metastasis (ortholog); FOUND IN cilium (inferred); cytoplasm (inferred); external side of plasma membrane (inferred) | | | | Squirrel | 22 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 626132697 | Spa17 | sperm autoantigenic protein 17 | ASSOCIATED WITH Merkel cell carcinoma (ortholog); Neoplasm Metastasis (ortholog); FOUND IN cilium (ortholog); cytoplasm (ortholog); external side of plasma membrane (ortholog) | | | | Black Rat | 18 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 1563726 | Spata16 | spermatogenesis associated 16 | INVOLVED IN spermatid development (ortholog); spermatogenesis (ortholog); ASSOCIATED WITH male infertility (ortholog); male infertility due to globozoospermia (ortholog); spermatogenic failure (ortholog); FOUND IN Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bispheno l A; bisphenol AF | 2 | 111413958 | 111794348 | Rat | 28 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1589777 | Ttc29 | tetratricopeptide repeat domain 29 | INVOLVED IN cilium movement (ortholog); cilium organization (ortholog); ASSOCIATED WITH spermatogenic failure 42 (ortholog); spermatogenic failure 5 (ortholog); FOUND IN sperm flagellum (ortholog); sperm principal piece (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; atrazine; bisphenol A | 19 | 46436526 | 46654891 | Rat | 61 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 39131152 | Gm53567 | predicted gene, 53567 | | 1 | 85257384 | 85267618 | Mouse | | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 16570259 | AC009950.2 | novel pseudogene | | | | | Human | | old_gene_name | gene, unitary_pseudogene |
| 18187808 | Gm55258 | predicted gene, 55258 | | | | | Mouse | | old_gene_name | gene, unprocessed_pseudogene |
| 1561814 | Garin1a | golgi associated RAB2 interactor 1A | INVOLVED IN acrosome assembly (ortholog); FOUND IN Golgi apparatus (ortholog); INTERACTS WITH bisphenol A; oxybenzone; paracetamol | 4 | 58845394 | 58856199 | Rat | 30 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1559779 | Ccdc54 | coiled-coil domain containing 54 | INTERACTS WITH acrylamide; bisphenol A; benzene-1,2,4-triol (ortholog) | 11 | 63693017 | 63696114 | Rat | 10 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1564147 | Garin1b | golgi associated RAB2 interactor 1B | INVOLVED IN acrosome assembly (ortholog); acrosome reaction (ortholog); FOUND IN Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; atrazine | 4 | 58880537 | 58903966 | Rat | 55 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1351414 | RANBP2 | RAN binding protein 2 | RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore c omplex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q. [provided by RefSeq, Jul 2008] | 2 | 108719482 | 109842301 | Human | 234 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1563917 | A630001G21Rikl | RIKEN cDNA A630001G21 gene like | FOUND IN nucleus (inferred); INTERACTS WITH bisphenol A; cadmium dichloride; copper atom | 9 | 93831074 | 93853415 | Rat | 8 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 6492000 | Ppia-ps1 | peptidylprolyl isomerase A, pseudogene 1 | | X | 12505530 | 12506265 | Rat | | old_gene_name | gene, pseudo, INFERRED [RefSeq] |
| 1596007 | Ppia-ps14 | peptidylprolyl isomerase A, pseudogene 14 | | X | 10087116 | 10087604 | Rat | | old_gene_name | gene, pseudo, MODEL [RefSeq] |