Sp100 (SP100 nuclear antigen) - Rat Genome Database

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Gene: Sp100 (SP100 nuclear antigen) Heterocephalus glaber
Analyze
Symbol: Sp100
Name: SP100 nuclear antigen
RGD ID: 18934803
Description: ENCODES a protein that exhibits chromo shadow domain binding (ortholog); identical protein binding (ortholog); kinase binding (ortholog); INVOLVED IN DNA damage response, signal transduction by p53 class mediator (ortholog); maintenance of protein location (ortholog); negative regulation of DNA-binding transcription factor activity (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); Joubert syndrome 22 (ortholog); Perlman syndrome (ortholog); FOUND IN Mre11 complex (ortholog); nuclear body (ortholog); nuclear periphery (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nuclear autoantigen Sp-100
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248433,983,040 - 4,061,930 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248433,982,920 - 4,058,081 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Sp100
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248433,983,040 - 4,061,930 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248433,982,920 - 4,058,081 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SP100
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382230,416,201 - 230,545,606 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2230,415,942 - 230,545,606 (+)EnsemblGRCh38hg38GRCh38
GRCh372231,280,916 - 231,410,321 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362230,989,115 - 231,118,561 (+)NCBINCBI36Build 36hg18NCBI36
Build 342231,106,485 - 231,206,745NCBI
Celera2225,057,025 - 225,186,692 (+)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2223,121,005 - 223,250,289 (+)NCBIHuRef
CHM1_12231,286,764 - 231,416,096 (+)NCBICHM1_1
T2T-CHM13v2.02230,899,281 - 231,028,667 (+)NCBIT2T-CHM13v2.0
Sp100
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39185,577,683 - 85,637,719 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl185,577,709 - 85,637,719 (+)EnsemblGRCm39 Ensembl
GRCm38185,649,948 - 85,709,998 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl185,649,988 - 85,709,998 (+)EnsemblGRCm38mm10GRCm38
MGSCv37187,546,625 - 87,606,023 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36187,481,185 - 87,532,732 (+)NCBIMGSCv36mm8
Celera188,624,849 - 88,674,129 (+)NCBICelera
Cytogenetic Map1C5NCBI
cM Map143.6NCBI
Sp100
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8993,758,975 - 93,825,068 (+)NCBIGRCr8
mRatBN7.2986,310,990 - 86,377,036 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl986,311,032 - 86,377,034 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx994,728,134 - 94,794,889 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0999,856,630 - 99,923,388 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0998,237,941 - 98,304,055 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0992,675,103 - 92,718,489 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl992,681,078 - 92,717,929 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0992,405,689 - 92,449,075 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0990,732,749 - 90,750,820 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4984,374,288 - 84,409,976 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1984,557,706 - 84,593,391 (+)NCBI
Celera983,734,331 - 83,769,903 (+)NCBICelera
Cytogenetic Map9q35NCBI
Sp100
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554534,773,030 - 4,853,814 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554534,774,739 - 4,856,238 (-)NCBIChiLan1.0ChiLan1.0
SP100
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213133,045,138 - 133,177,230 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B133,062,928 - 133,192,182 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B117,673,152 - 117,799,911 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B236,474,298 - 236,601,277 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B236,496,446 - 236,601,096 (+)Ensemblpanpan1.1panPan2
SP100
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12542,538,428 - 42,635,825 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2542,538,571 - 42,635,649 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2543,163,525 - 43,261,071 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02542,794,971 - 42,892,656 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2542,795,086 - 42,892,647 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12542,724,896 - 42,822,209 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02542,566,980 - 42,664,684 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02542,722,157 - 42,819,867 (+)NCBIUU_Cfam_GSD_1.0
Sp100
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303184,708,642 - 184,803,432 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365256,136,343 - 6,231,051 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100517129
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.115131,299,923 - 131,381,253 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215145,104,815 - 145,137,478 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SP100
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110116,454,261 - 116,587,093 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10116,459,050 - 116,590,215 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604082,883,256 - 83,027,176 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004868032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004868035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004868036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004868037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002390301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002390302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002390303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_206223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01088032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01088033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000004636   ⟹   ENSHGLP00000004574
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248433,983,040 - 4,061,930 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000004637   ⟹   ENSHGLP00000004575
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248434,011,122 - 4,061,930 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000004638   ⟹   ENSHGLP00000004576
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248434,011,122 - 4,061,930 (+)Ensembl
RefSeq Acc Id: XM_004868032   ⟹   XP_004868089
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248433,982,920 - 4,058,081 (+)NCBI
RefSeq Acc Id: XM_004868035   ⟹   XP_004868092
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248433,982,920 - 4,058,081 (+)NCBI
RefSeq Acc Id: XM_004868036   ⟹   XP_004868093
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248433,982,920 - 4,055,742 (+)NCBI
RefSeq Acc Id: XM_004868037   ⟹   XP_004868094
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248433,982,920 - 4,055,733 (+)NCBI
RefSeq Acc Id: XM_021247060   ⟹   XP_021102719
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248433,982,920 - 4,058,081 (+)NCBI
RefSeq Acc Id: XM_021247061   ⟹   XP_021102720
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248433,983,423 - 4,058,081 (+)NCBI
RefSeq Acc Id: XM_021247062   ⟹   XP_021102721
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248433,982,941 - 4,058,081 (+)NCBI
RefSeq Acc Id: XM_021247063   ⟹   XP_021102722
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248433,982,920 - 4,055,742 (+)NCBI
RefSeq Acc Id: XM_021247064   ⟹   XP_021102723
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248433,982,920 - 4,055,742 (+)NCBI
RefSeq Acc Id: XM_021247066   ⟹   XP_021102725
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248433,982,920 - 4,055,733 (+)NCBI
RefSeq Acc Id: XM_021247067   ⟹   XP_021102726
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248433,982,920 - 4,055,742 (+)NCBI
RefSeq Acc Id: XR_002390301
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248433,982,920 - 4,056,729 (+)NCBI
RefSeq Acc Id: XR_002390302
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248433,982,920 - 4,056,729 (+)NCBI
RefSeq Acc Id: XR_002390303
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248433,982,920 - 4,055,727 (+)NCBI
RefSeq Acc Id: XR_206223
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248433,982,920 - 4,056,077 (+)NCBI
RefSeq Acc Id: XP_004868089   ⟸   XM_004868032
- Peptide Label: isoform X1
- UniProtKB: G5ASW1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102719   ⟸   XM_021247060
- Peptide Label: isoform X2
- UniProtKB: G5ASW1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004868092   ⟸   XM_004868035
- Peptide Label: isoform X4
- UniProtKB: G5ASW1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102723   ⟸   XM_021247064
- Peptide Label: isoform X8
RefSeq Acc Id: XP_004868093   ⟸   XM_004868036
- Peptide Label: isoform X5
RefSeq Acc Id: XP_021102726   ⟸   XM_021247067
- Peptide Label: isoform X10
RefSeq Acc Id: XP_021102722   ⟸   XM_021247063
- Peptide Label: isoform X6
RefSeq Acc Id: XP_004868094   ⟸   XM_004868037
- Peptide Label: isoform X7
RefSeq Acc Id: XP_021102725   ⟸   XM_021247066
- Peptide Label: isoform X9
RefSeq Acc Id: XP_021102721   ⟸   XM_021247062
- Peptide Label: isoform X3
- UniProtKB: G5ASW1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102720   ⟸   XM_021247061
- Peptide Label: isoform X3
- UniProtKB: G5ASW1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000004575   ⟸   ENSHGLT00000004637
Ensembl Acc Id: ENSHGLP00000004576   ⟸   ENSHGLT00000004638
Ensembl Acc Id: ENSHGLP00000004574   ⟸   ENSHGLT00000004636


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003347 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000004636 ENTREZGENE
  ENSHGLT00000004637 ENTREZGENE
Gene3D-CATH Bromodomain-like UniProtKB/TrEMBL
  SAND domain-like UniProtKB/TrEMBL
  Zinc/RING finger domain, C3HC4 (zinc finger) UniProtKB/TrEMBL
InterPro Bromodomain UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/TrEMBL
  HSR_dom UniProtKB/TrEMBL
  SAND-like_dom_sf UniProtKB/TrEMBL
  SAND_dom UniProtKB/TrEMBL
  Sp110/Sp140/Sp140L-like UniProtKB/TrEMBL
  Zinc_finger_PHD-type_CS UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene Sp100 ENTREZGENE
PANTHER NUCLEAR AUTOANTIGEN SP-100 UniProtKB/TrEMBL
  NUCLEAR BODY PROTEIN SP140 UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/TrEMBL
  HSR UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
  SAND UniProtKB/TrEMBL
PROSITE HSR UniProtKB/TrEMBL
  SAND UniProtKB/TrEMBL
  ZF_PHD_1 UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/TrEMBL
SMART BROMO UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
  SAND UniProtKB/TrEMBL
Superfamily-SCOP Bromodomain UniProtKB/TrEMBL
  FYVE/PHD zinc finger UniProtKB/TrEMBL
  SAND domain-like UniProtKB/TrEMBL
UniProt G5ASW1 ENTREZGENE, UniProtKB/TrEMBL