Med26 (mediator complex subunit 26)

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Gene: Med26 (mediator complex subunit 26) Mus musculus

Analyze

Symbol:

Med26

Name:

mediator complex subunit 26

RGD ID:

1557558

MGI Page

MGI

Description:

Predicted to have transcription coregulator activity. Predicted to be involved in positive regulation of gene expression and regulation of transcription by RNA polymerase II. Localizes to mediator complex. Is expressed in central nervous system; limb; and retina. Orthologous to human MED26 (mediator complex subunit 26); PARTICIPATES IN RNA polymerase II transcription pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

5730493L18Rik; AI414941; AW495270; cofactor required for Sp1 transcriptional activation subunit 7; cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa; Cr; CRSP complex subunit 7; Crsp7; mediator of RNA polymerase II transcription subunit 26

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MED26 (mediator complex subunit 26)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Med26 (mediator complex subunit 26)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Med26 (mediator complex subunit 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MED26 (mediator complex subunit 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MED26 (mediator complex subunit 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Med26 (mediator complex subunit 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MED26 (mediator complex subunit 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	MED26 (mediator complex subunit 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Med26 (mediator complex subunit 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Med26 (mediator complex subunit 26)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Homo sapiens (human):	MED26 (mediator complex subunit 26)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Danio rerio (zebrafish):	crsp7 (cofactor required for Sp1 transcriptional activation, subunit 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Drosophila melanogaster (fruit fly):	MED26	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER\|Roundup\|TreeFam)

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	73,248,402 - 73,302,154 (-)	NCBI	GRCm39		mm39
GRCm38	8	72,494,555 - 72,548,310 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	72,494,561 - 72,548,270 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	75,018,457 - 75,072,209 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	8	75,423,550 - 75,477,259 (-)	NCBI			mm8
Celera	8	76,839,095 - 76,894,758 (-)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (EXP)

2,3',4,4',5-Pentachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

aflatoxin B2 (ISO)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (ISO)

butanal (ISO)

cadmium dichloride (ISO)

copper(II) sulfate (ISO)

dexamethasone (ISO)

diazinon (ISO)

enzyme inhibitor (ISO)

folic acid (EXP)

formaldehyde (ISO)

indometacin (ISO)

paracetamol (EXP,ISO)

potassium chromate (ISO)

quercetin (ISO)

urethane (ISO)

valproic acid (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of gene expression (IBA)

regulation of transcription by RNA polymerase II (IBA,ISO)

Cellular Component

core mediator complex (IBA)

mediator complex (IBA,IDA,ISO)

nucleoplasm (TAS)

nucleus (IEA)

Molecular Function

protein binding (IPI)

transcription coregulator activity (IBA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA polymerase II transcription pathway (ISO)

References

References - curated


1.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2.	MGD data from the GO Consortium
3.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4.	Poss ZC, etal., Crit Rev Biochem Mol Biol. 2013 Nov-Dec;48(6):575-608. doi: 10.3109/10409238.2013.840259. Epub 2013 Oct 3.
5.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:11042159	PMID:11076861	PMID:11591653	PMID:12477932	PMID:12520002	PMID:12904583	PMID:14610273	PMID:14681479	PMID:16141072	PMID:16141073
PMID:16602821	PMID:18799693	PMID:19362612	PMID:20059953	PMID:20362541	PMID:20508642	PMID:21267068	PMID:21873635	PMID:25575120	PMID:32325033

Genomics

Comparative Map Data

Med26
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	73,248,402 - 73,302,154 (-)	NCBI	GRCm39		mm39
GRCm38	8	72,494,555 - 72,548,310 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	72,494,561 - 72,548,270 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	75,018,457 - 75,072,209 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	8	75,423,550 - 75,477,259 (-)	NCBI			mm8
Celera	8	76,839,095 - 76,894,758 (-)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI

MED26
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	19	16,574,907 - 16,629,062 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	19	16,574,919 - 16,628,204 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	19	16,685,718 - 16,739,015 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	16,546,718 - 16,600,015 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	19	16,547,837 - 16,599,754	NCBI
Celera	19	16,587,557 - 16,640,853 (-)	NCBI
Cytogenetic Map	19	p13.11	NCBI
HuRef	19	16,254,284 - 16,307,727 (-)	NCBI		HuRef
CHM1_1	19	16,685,204 - 16,738,514 (-)	NCBI		CHM1_1

Med26
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	16	19,001,061 - 19,050,874 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	19,001,061 - 19,050,874 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	18,863,765 - 18,913,816 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	17,716,525 - 17,767,690 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	16	17,716,790 - 17,766,106 (+)	NCBI
Celera	16	17,565,596 - 17,569,307 (+)	NCBI		Celera
Cytogenetic Map	16	p14	NCBI

Med26
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955524	1,166,582 - 1,201,902 (+)	NCBI	ChiLan1.0	ChiLan1.0

MED26
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	19	17,043,523 - 17,060,213 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
Mhudiblu_PPA_v0	19	16,065,074 - 16,118,385 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

MED26
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	45,923,034 - 45,977,118 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Med26
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936596	4,008,155 - 4,061,277 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MED26
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	2	60,984,233 - 61,035,661 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	60,571,076 - 60,622,193 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MED26
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	15,082,453 - 15,136,412 (-)	NCBI

Med26
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624908	870,181 - 912,685 (+)	NCBI

Position Markers

AW495270

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	8	72,495,100 - 72,495,245	UniSTS	GRCm38
MGSCv37	8	75,018,999 - 75,019,144	UniSTS	GRCm37
Celera	8	76,839,637 - 76,839,782	UniSTS
Cytogenetic Map	8	B3.3	UniSTS

AI414941

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	8	72,494,883 - 72,494,988	UniSTS	GRCm38
MGSCv37	8	75,018,782 - 75,018,887	UniSTS	GRCm37
Celera	8	76,839,420 - 76,839,525	UniSTS
Cytogenetic Map	8	B3.3	UniSTS
Whitehead/MRC_RH	8	772.55	UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4140967	Bmd39_m	bone mineral density 39 (mouse)			Not determined		8	32016544	117238700	Mouse
1558875	Eae31_m	experimental allergic encephalomyelitis susceptibility 31 (mouse)			Not determined		8	34642776	114837007	Mouse
1301013	Capsq4_m	capsaicin sensitivity related QTL 4 (mouse)			Not determined		8	36163000	92728652	Mouse
27226754	Femd6_m	femur midshaft diameter 6, 10 week (mouse)					8	37400000	109600000	Mouse
12904744	Carcdq1_m	cardiac collagen deposition QTL 1 (mouse)					8	39709256	94689598	Mouse
1301544	Iba3_m	induction of brown adipocytes 3 (mouse)			Not determined		8	44294880	78295025	Mouse
1301717	Adip4_m	adiposity 4 (mouse)			Not determined		8	47637030	81637146	Mouse
10766453	Char11_m	P. chabaudi malaria resistance QTL 11 (mouse)					8	47637030	81637146	Mouse
1301441	Skull11_m	skull morphology 11 (mouse)			Not determined		8	47737134	81737254	Mouse
1357715	Alaa3_m	alopecia areata 3 (mouse)			Not determined		8	48792939	82793021	Mouse
14746987	Manh64_m	mandible shape 64 (mouse)					8	50053306	84053306	Mouse
14747005	Mancz7_m	mandible centroid size 7 (mouse)					8	50053306	84053306	Mouse
14700686	Civq3_m	cerebral infarct volume QTL 3 (mouse)					8	51882191	85882191	Mouse
1301506	Aevm1_m	autoimmune extremity vasculitis in MRL mice 1 (mouse)			Not determined		8	54287817	88287993	Mouse
1301952	Im3_m	immunoregulatory 3 (mouse)			Not determined		8	54706614	88706763	Mouse
10412287	Carg3_m	Candida albicans resistance gene 3 (mouse)			Not determined		8	55545028	89545028	Mouse
11353828	Gf7_m	gonadal fat pad weight 7 (mouse)					8	58201479	92201479	Mouse
10043975	Obq31_m	obesity QTL 31 (mouse)			Not determined		8	58409776	92409776	Mouse
1301688	Orch6_m	autoimmune orchitis resistance 6 (mouse)			Not determined		8	60786850	94786976	Mouse
4141285	Tgq18_m	triglyceride QTL 18 (mouse)			Not determined			63460107	97460107	Mouse
4141797	Skmw16_m	skeletal muscle weight 16 (mouse)			Not determined		8	63939547	97939696	Mouse
1357787	Vtbt5_m	vertebral trabecular bone trait 5 (mouse)			Not determined		8	65357768	99357920	Mouse
10043992	Hbnr11_m	Heligmosomoides bakeri nematode resistance 11 (mouse)			Not determined		8	65600207	99600347	Mouse
10766466	Char12_m	P. chabaudi malaria resistance QTL 12 (mouse)					8	68269827	82600347	Mouse
1301767	Fcsa2_m	femoral cross-sectional area 2 (mouse)			Not determined		8	70305375	104305495	Mouse
4142283	Imraq2_m	immune response to AAV2 QTL 2 (mouse)			Not determined		8	70305375	104305495	Mouse
1558780	Idd22_m	insulin dependent diabetes susceptibility 22 (mouse)			Not determined		8	71102903	105103009	Mouse
4141395	Char2a_m	P. chabaudi malaria resistance QTL 2a (mouse)			Not determined			71136783	90202598	Mouse
4142023	W3q5_m	weight 3 weeks QTL 5 (mouse)			Not determined			71287817	123895615	Mouse
1357708	Orq1_m	ovulation rate QTL 1 (mouse)			Not determined		8	71287817	123895615	Mouse
1301872	Cd4ts3_m	CD4 T cell subset 3 (mouse)			Not determined		8	71396181	105396393	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	276
Count of miRNA genes:	238
Interacting mature miRNAs:	251
Transcripts:	ENSMUST00000058534
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_027485	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC172623	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK017726	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK042883	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK054023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK083035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC024555	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC054737	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY059601	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466525	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000058534 ⟹ ENSMUSP00000058697

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	8	72,494,561 - 72,548,270 (-)	Ensembl

RefSeq Acc Id:

NM_027485 ⟹ NP_081761

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	8	73,248,402 - 73,302,154 (-)	NCBI
GRCm38	8	72,494,558 - 72,548,310 (-)	NCBI
MGSCv37	8	75,018,457 - 75,072,209 (-)	RGD
Celera	8	76,839,095 - 76,894,758 (-)	RGD
cM Map	8		ENTREZGENE

Sequence:

show sequence

AGCGTGGCGCCGACGCTGCGTGCGGCGCGGGTTACCCAGAGTGCTCAGCGCGGGGGGCAGCTCA
CTGGAGTTTGGTTCTCGAGGCGGCGGCGGCGGTGGTGGCGGAGGCTCCTCCGTCGGCTCCTCCT
CCTCGCTCGGCGGTGGCGGCGGTGGTCCGGGGCCTGAGCTCCGGTCCCCTCCGCTTCCCTCCGT
CCTCGCCATCTCCCCGAGCGCCTTGACCTCCTCCGGCGCCGCGGGGAACATGCGGCTCCGTTCC
CGGAGGCCGGCGAGTGACTGACCCGCGTTCCCCCTCCTCAGCCTGCCCGCCCGCCGGCCCGGCC
GCTCCCCCCCGCTTCGCCCAGGCAATGACAGCGGCTCCGGCGTCTCCGCAGCAGATGAGGGACC
GGCTGCTACAGGCCATCGACTCCCAGAGCAACATCCGGAACATGGTGGCAGTGTTGGAAGTGAT
CTCCAGTCTGGAGAGATACCCCATCACCAAAGAGGCACTGGAGGAGACACGACTAGGGAAGCTC
ATCAATGATGTCCGCAAGAAAACCAAGAATGAGGAGCTGGCCAAGCGGGCCAAGAGGCTGCTAC
GAAGCTGGCAGAAGCTCATCGAGCCTGTACACCAGAACGAAGTGGCACTACGGGCACTGGCAGG
AGCTGCAGGCTCTGCCAATGGGGGTGCGCACAACTGCCGACCAGAGATGGGAGTGGCTGGTGCA
CCCAAGAGCATCCATGACCTGAAGAATCGCAACGACATCCAAAGGCTCCCTGGGCAACGGCTAG
ATAGGCTGGGCAGCCGTAAGCGCAGGGGGGACCAGCGTGACCTGGGCCACCCAGGGCCACCCCA
CAAAGTTTCCAAAGGCAGTCCTGACCCTCTGGTTCCCAATGCATCCCCTCTCCCCACCAATGGG
ATCAGCGGGAGCCCAGAGAGCTTACCCAGCCCCCTGGATGGCAGTGGGCACTTGGGCCCTGATG
GCAGCCGCCTGGAGCCCAGTGATAATGAGAAGCACAGCACCAAGATTCCCGTGAACGCCGTGCG
GCCGCGCCCCAGCTCTCCCGGCTTGGGCAAACCCCCAGTTCCCTGCCTGCAGACCAAGGCTGCA
CAGTTGCAGCAGTTGGACAGGGCAGATGAGTCCCCAGGCCCTCCCTATCCCAGGGGGTCCTCTC
GCTGCTCCTTCAGCCCCCGGAACTCACGGCACGAAGGCTCCTTTTCACGGCATCGGAGCTCTTA
CATACCCAAGGGCCAGGTGTCCAGCCCTTCCCCATGGCCCCAGCCACCGGACAACACGCAGGTA
CCATCCCCACTCCCGCTGGCCCAGCCACCCACGCCCCCTGTGCGCCGTCAGGAGCTGCTGCCTA
ATGCTGAGAGCCCTGTGCACTGGCCAGAGCAGTCTGAGGGCCACCCACGGCTAACGGGGCCAGC
CTGCAGGGCTGGATTTTCTCCAGATTCCTCCAAGGCGGACAGTGATGCTACCTCTTCGGGTGGC
TCGGACAGCAAAAAGAAAAAGAGGTACCGACCTCGAGACTACACAGTGAACTTGGACGGGCAGG
TGGCTGAGGCTGGTGTTAAACCTGTGCGGTTAAAAGAGCGGAAGCTCACCTTTGACCCCATGAC
AAGACAGATCAGGCCTCTGACCCAGAAAGAGCCGGTGCGGGCTGACAGCCCAGTACCCACAGAG
CAGCTGCCTAGGACAGAGCTGGAGCAGCAGGAGGTCAAGGCCAGCCTCCAGAGCCCTTTTGAGC
AGACGAACTGGAAGGAGCTATCACGAAATGAGATCATACAGTCCTACCTGAGCCGCCAGAGCAG
CTTGCTATCCTCCTCAGGCGCACAGACCCCAGGTGCGCACCACTTTATGGCTGAATACCTGAAG
CAGGAGGAGAGCAGTCGGCAAGGGGCCCGGCAGCCCCATGTGCTGCTACCACTGCCCACACCCA
CTGACCTACCAGGGCTCACACGTGAGGTCACGCAGGATGATCTGGACAGAATCCAGGCCCAGCA
ATGGCCAGGGGTTAACGGGTGTGAAGACACACAGGGTAATTGGTATGACTGGACACAGTGTATA
TCGCTCGACCCTCATGGTGACGATGGGCGCTTGAACATTCTGCCTTATGTCTGCTTGGACTGAG
CACCTGACCTGGCCATCATGTGCATTCCCACCTCGCAAGGGTTAGGCTGGCCAGCTGAGAAGGC
GAGCATGAGGCTCGCTCTCCACCATCCTTTTGTGAAATGCTGCTACCAGTTTACTAACGATTGC
AAAGGAAGGGCCGCTCGGGGGAGGGGCAGATAGATGGCTGAAATCTATAGTAAGCCAGCTATAA
AGCGTTAGTCCCCCATCCCAGAAGAGGTGCAGAACCACTCTAAGCACCGAAGGCAGGGACCTCA
GTAGCAGGCAGGCACAGGAACCCTGTGGAAGAGGTTACCTTAACAGCAACAGACACATCTCTTC
TTTGCATCTCTTGCTCTTTGGCCCTGGTGTCTCTGAGGCACAGGCTACTCTCGAGCCAGTGGTT
TTTTTTGTCGCCCTCGTGTTGTGCGCTGGAAGCTTCTCTGCTGTGGTGAACCCTGGTGTTGTGT
GGGTGGGCCAGCCTCACCCACACTGCACAGTCGTCTGCCCATTTGTATATGGTTTCAGTTCAGT
CCCAGTTCTTAAAAGAAATGCTGCAGAAACTTGAGTTTTCTCATTTATTTCATTCTCTTTTTTC
CCCTACCACCAGCCAAATGACTTTTCCTTCCCTTCTTTCCTTTTCTGCACAACTCTAGAAAAAT
GCCATCTTTCTAGAGTCTTTAACCCACAAAGTTCCCGAGGGTGCTACTGGTGTGAGTTGCCCTG
GTGGGCTAGGGAAGAGCCGTCTGTTGGCTGGAAACACTCATAACCATTCCTTTAGATTCGTTTG
CCTTATGGTCATAAACGCGATTTGCAAAAACAAGGAGCCTTAGTGAATGTACAGTACCTAGACT
TCTGTGTTCGCGCAGAAGGGAGCAACTTTGCTATTTGGTCCAGTAAGTGGACAACTTGTGATAT
AAATGTGGAAATAAAAAAAATATTTGCACAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_081761	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH24555	(Get FASTA)	NCBI Sequence Viewer
	AAH54737	(Get FASTA)	NCBI Sequence Viewer
	BAB30898	(Get FASTA)	NCBI Sequence Viewer
	BAC38738	(Get FASTA)	NCBI Sequence Viewer
	EDL10804	(Get FASTA)	NCBI Sequence Viewer
	Q7TN02	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_081761 ⟸ NM_027485

- UniProtKB:

Q7TN02 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MTAAPASPQQMRDRLLQAIDSQSNIRNMVAVLEVISSLERYPITKEALEETRLGKLINDVRKKT
KNEELAKRAKRLLRSWQKLIEPVHQNEVALRALAGAAGSANGGAHNCRPEMGVAGAPKSIHDLK
NRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPHKVSKGSPDPLVPNASPLPTNGISGSPESL
PSPLDGSGHLGPDGSRLEPSDNEKHSTKIPVNAVRPRPSSPGLGKPPVPCLQTKAAQLQQLDRA
DESPGPPYPRGSSRCSFSPRNSRHEGSFSRHRSSYIPKGQVSSPSPWPQPPDNTQVPSPLPLAQ
PPTPPVRRQELLPNAESPVHWPEQSEGHPRLTGPACRAGFSPDSSKADSDATSSGGSDSKKKKR
YRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIRPLTQKEPVRADSPVPTEQLPRTELE
QQEVKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMAEYLKQEESSRQG
ARQPHVLLPLPTPTDLPGLTREVTQDDLDRIQAQQWPGVNGCEDTQGNWYDWTQCISLDPHGDD
GRLNILPYVCLD

hide sequence

RefSeq Acc Id:

ENSMUSP00000058697 ⟸ ENSMUST00000058534

Protein Domains

TFIIS N-terminal

Promoters

RGD ID:

8667481

Promoter ID:

EPDNEW_M11772

Type:

initiation region

Name:

Med26_1

Description:

Mus musculus mediator complex subunit 26 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	8	72,548,247 - 72,548,307	EPDNEW

RGD ID:

6843229

Promoter ID:

MM_KWN:54875

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

AK054489_1700085D22RIK, NM_027485, XM_001478638_GM3847

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	8	75,072,076 - 75,072,842 (-)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1917875	AgrOrtholog
Ensembl Genes	ENSMUSG00000045248	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSMUSP00000058697	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000058534	ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH	1.20.930.10	UniProtKB/Swiss-Prot
InterPro	MED26	UniProtKB/Swiss-Prot
	Med26_C	UniProtKB/Swiss-Prot
	Med26_Mid	UniProtKB/Swiss-Prot
	TFIIS/CRSP70_N_sub	UniProtKB/Swiss-Prot
	TFIIS/LEDGF_dom_sf	UniProtKB/Swiss-Prot
	TFIIS_N	UniProtKB/Swiss-Prot
KEGG Report	mmu:70625	UniProtKB/Swiss-Prot
MGD	MGI:1917875	ENTREZGENE
NCBI Gene	70625	ENTREZGENE
PANTHER	PTHR15201	UniProtKB/Swiss-Prot
Pfam	Med26	UniProtKB/Swiss-Prot
	Med26_C	UniProtKB/Swiss-Prot
	Med26_M	UniProtKB/Swiss-Prot
PhenoGen	Med26	PhenoGen
PROSITE	TFIIS_N	UniProtKB/Swiss-Prot
SMART	TFS2N	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF47676	UniProtKB/Swiss-Prot
UniGene	Mm.235885	ENTREZGENE
	Mm.440960	ENTREZGENE
UniProt	MED26_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	Q8BUP9	UniProtKB/Swiss-Prot
	Q8R1G7	UniProtKB/Swiss-Prot
	Q9CS67	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

RGD Manual Annotations