PATHWAY ONTOLOGY - ANNOTATIONS
The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml ).
Term: linoleic acid metabolic pathway
Accession: PW:0000523
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Definition: Those enzymatic reactions involved in the synthesis, utilization or degradation of linoleic acid - an unsaturated omega-6 fatty acid. Linoleic acid is an essential fatty acid that humans and other animals cannot synthesize and must obtain from diet.
Synonyms: related_synonym: Linoleic acid (LA) metabolism; linoleic acid metabolic process
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Alox12e
arachidonate 12-lipoxygenase, epidermal
IEA
KEGG
rno:00591
NCBI chr10:55,034,392...55,041,857
Ensembl chr10:55,034,392...55,041,928
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Alox15
arachidonate 15-lipoxygenase
IEA
KEGG
rno:00591
NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
IEA
KEGG
rno:00591
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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Cyp2c11
cytochrome P450, subfamily 2, polypeptide 11
IEA
KEGG
rno:00591
NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
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Cyp2c12
cytochrome P450, family 2, subfamily c, polypeptide 12
IEA
KEGG
rno:00591
NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019
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Cyp2c13
cytochrome P450, family 2, subfamily c, polypeptide 13
IEA
KEGG
rno:00591
NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191
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Cyp2c22
cytochrome P450, family 2, subfamily c, polypeptide 22
IEA
KEGG
rno:00591
NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738
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Cyp2c23
cytochrome P450, family 2, subfamily c, polypeptide 23
IEA
KEGG
rno:00591
NCBI chr 1:242,889,218...242,913,869
Ensembl chr 1:242,889,224...242,913,858
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Cyp2c7
cytochrome P450, family 2, subfamily c, polypeptide 7
IEA
KEGG
rno:00591
NCBI chr 1:237,332,641...237,388,714
Ensembl chr 1:237,332,659...237,388,709
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
IEA
KEGG
rno:00591
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Cyp2j16
cytochrome P450, family 2, subfamily j, polypeptide 16
IEA
KEGG
rno:00591
NCBI chr 5:111,089,438...111,138,918
Ensembl chr 5:111,088,674...111,139,013
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Cyp2j3
cytochrome P450, family 2, subfamily j, polypeptide 3
IEA
KEGG
rno:00591
NCBI chr 5:111,219,921...111,244,987
Ensembl chr 5:111,178,703...111,244,794
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Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
IEA
KEGG
rno:00591
NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
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Cyp3a18
cytochrome P450, family 3, subfamily a, polypeptide 18
IEA
KEGG
rno:00591
NCBI chr12:8,880,509...8,930,382
Ensembl chr12:8,880,528...8,930,381
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
IEA
KEGG
rno:00591
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Cyp3a23-3a1
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
IEA
KEGG
rno:00591
NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 Ensembl chr12:9,254,475...9,285,030
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Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
IEA
KEGG
rno:00591
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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Cyp4a1
cytochrome P450, family 4, subfamily a, polypeptide 1
IDA
RGD
PMID:10362749
RGD:2303410
NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
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Cyp4a2
cytochrome P450, family 4, subfamily a, polypeptide 2
IDA
RGD
PMID:10362749
RGD:2303410
NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
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Cyp4a3
cytochrome P450, family 4, subfamily a, polypeptide 3
IDA
RGD
PMID:10362749
RGD:2303410
NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463
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Elovl4
ELOVL fatty acid elongase 4
ISO
SMPDB
SMP:00018
NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697
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Elovl5
ELOVL fatty acid elongase 5
ISO
SMPDB
SMP:00018
NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284
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Fads1
fatty acid desaturase 1
ISO
SMPDB
SMP:00018
NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
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Fads2
fatty acid desaturase 2
ISO
SMPDB
SMP:00018
NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
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Pla2g10
phospholipase A2, group X
IEA
KEGG
rno:00591
NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000
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Pla2g12a
phospholipase A2, group XIIA
IEA
KEGG
rno:00591
NCBI chr 2:218,436,497...218,452,742
Ensembl chr 2:218,436,513...218,452,740
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Pla2g12b
phospholipase A2, group XIIB
IEA
KEGG
rno:00591
NCBI chr20:27,369,196...27,389,517
Ensembl chr20:27,370,266...27,388,743
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Pla2g1b
phospholipase A2 group IB
IEA
KEGG
rno:00591
NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226
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Pla2g2a
phospholipase A2 group IIA
IEA
KEGG
rno:00591
NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
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Pla2g2c
phospholipase A2, group IIC
IEA
KEGG
rno:00591
NCBI chr 5:150,959,365...150,981,388
Ensembl chr 5:150,959,182...150,981,377
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Pla2g2d
phospholipase A2, group IID
IEA
KEGG
rno:00591
NCBI chr 5:151,016,010...151,022,531
Ensembl chr 5:151,018,870...151,022,525
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Pla2g2f
phospholipase A2, group IIF
IEA
KEGG
rno:00591
NCBI chr 5:150,986,788...150,993,175
Ensembl chr 5:150,986,788...150,993,175
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Pla2g3
phospholipase A2, group III
IEA
KEGG
rno:00591
NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913
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Pla2g4a
phospholipase A2 group 4A
IEA
KEGG
rno:00591
NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
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Pla2g4b
phospholipase A2 group IVB
IEA ISO
KEGG SMPDB
SMP:00018 rno:00591
NCBI chr 3:107,004,238...107,013,853
Ensembl chr 3:107,005,489...107,013,853
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Pla2g4e
phospholipase A2, group IVE
IEA
KEGG
rno:00591
NCBI chr 3:107,132,540...107,198,609
Ensembl chr 3:107,132,541...107,198,233
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Pla2g4f
phospholipase A2, group IVF
IEA
KEGG
rno:00591
NCBI chr 3:107,249,053...107,266,201
Ensembl chr 3:107,250,075...107,264,689
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Pla2g5
phospholipase A2, group V
IEA
KEGG
rno:00591
NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
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Pla2g6
phospholipase A2 group VI
IEA
KEGG
rno:00591
NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
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Plb1
phospholipase B1
IEA
KEGG
rno:00591
NCBI chr 6:24,087,051...24,227,167
Ensembl chr 6:24,089,214...24,210,117
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