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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:linoleic acid metabolic pathway
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Accession:PW:0000523 term browser browse the term
Definition:Those enzymatic reactions involved in the synthesis, utilization or degradation of linoleic acid - an unsaturated omega-6 fatty acid. Linoleic acid is an essential fatty acid that humans and other animals cannot synthesize and must obtain from diet.
Synonyms:related_synonym: Linoleic acid (LA) metabolism;   linoleic acid metabolic process



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linoleic acid metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12e arachidonate 12-lipoxygenase, epidermal IEA KEGG rno:00591 NCBI chr10:55,034,392...55,041,857
Ensembl chr10:55,034,392...55,041,928
JBrowse link
G Alox15 arachidonate 15-lipoxygenase IEA KEGG rno:00591 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 IEA KEGG rno:00591 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 IEA KEGG rno:00591 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 IEA KEGG rno:00591 NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 IEA KEGG rno:00591 NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191
JBrowse link
G Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 IEA KEGG rno:00591 NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738
JBrowse link
G Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 IEA KEGG rno:00591 NCBI chr 1:242,889,218...242,913,869
Ensembl chr 1:242,889,224...242,913,858
JBrowse link
G Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 IEA KEGG rno:00591 NCBI chr 1:237,332,641...237,388,714
Ensembl chr 1:237,332,659...237,388,709
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 IEA KEGG rno:00591 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp2j16 cytochrome P450, family 2, subfamily j, polypeptide 16 IEA KEGG rno:00591 NCBI chr 5:111,089,438...111,138,918
Ensembl chr 5:111,088,674...111,139,013
JBrowse link
G Cyp2j3 cytochrome P450, family 2, subfamily j, polypeptide 3 IEA KEGG rno:00591 NCBI chr 5:111,219,921...111,244,987
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 IEA KEGG rno:00591 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 IEA KEGG rno:00591 NCBI chr12:8,880,509...8,930,382
Ensembl chr12:8,880,528...8,930,381
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 IEA KEGG rno:00591 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 IEA KEGG rno:00591 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 IEA KEGG rno:00591 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 IDA RGD PMID:10362749 RGD:2303410 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 IDA RGD PMID:10362749 RGD:2303410 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 IDA RGD PMID:10362749 RGD:2303410 NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463
JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 ISO SMPDB SMP:00018 NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 ISO SMPDB SMP:00018 NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284
JBrowse link
G Fads1 fatty acid desaturase 1 ISO SMPDB SMP:00018 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
JBrowse link
G Fads2 fatty acid desaturase 2 ISO SMPDB SMP:00018 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
JBrowse link
G Pla2g10 phospholipase A2, group X IEA KEGG rno:00591 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000
JBrowse link
G Pla2g12a phospholipase A2, group XIIA IEA KEGG rno:00591 NCBI chr 2:218,436,497...218,452,742
Ensembl chr 2:218,436,513...218,452,740
JBrowse link
G Pla2g12b phospholipase A2, group XIIB IEA KEGG rno:00591 NCBI chr20:27,369,196...27,389,517
Ensembl chr20:27,370,266...27,388,743
JBrowse link
G Pla2g1b phospholipase A2 group IB IEA KEGG rno:00591 NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226
JBrowse link
G Pla2g2a phospholipase A2 group IIA IEA KEGG rno:00591 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
G Pla2g2c phospholipase A2, group IIC IEA KEGG rno:00591 NCBI chr 5:150,959,365...150,981,388
Ensembl chr 5:150,959,182...150,981,377
JBrowse link
G Pla2g2d phospholipase A2, group IID IEA KEGG rno:00591 NCBI chr 5:151,016,010...151,022,531
Ensembl chr 5:151,018,870...151,022,525
JBrowse link
G Pla2g2f phospholipase A2, group IIF IEA KEGG rno:00591 NCBI chr 5:150,986,788...150,993,175
Ensembl chr 5:150,986,788...150,993,175
JBrowse link
G Pla2g3 phospholipase A2, group III IEA KEGG rno:00591 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913
JBrowse link
G Pla2g4a phospholipase A2 group 4A IEA KEGG rno:00591 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pla2g4b phospholipase A2 group IVB IEA
ISO
KEGG
SMPDB
SMP:00018 rno:00591 NCBI chr 3:107,004,238...107,013,853
Ensembl chr 3:107,005,489...107,013,853
JBrowse link
G Pla2g4e phospholipase A2, group IVE IEA KEGG rno:00591 NCBI chr 3:107,132,540...107,198,609
Ensembl chr 3:107,132,541...107,198,233
JBrowse link
G Pla2g4f phospholipase A2, group IVF IEA KEGG rno:00591 NCBI chr 3:107,249,053...107,266,201
Ensembl chr 3:107,250,075...107,264,689
JBrowse link
G Pla2g5 phospholipase A2, group V IEA KEGG rno:00591 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
JBrowse link
G Pla2g6 phospholipase A2 group VI IEA KEGG rno:00591 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
JBrowse link
G Plb1 phospholipase B1 IEA KEGG rno:00591 NCBI chr 6:24,087,051...24,227,167
Ensembl chr 6:24,089,214...24,210,117
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      lipid metabolic pathway 488
        fatty acid metabolic pathway 191
          linoleic acid metabolic pathway 40
paths to the root