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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased thymocyte number
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Accession:MP:0000714 term browser browse the term
Definition:greater than expected number of immature T cells located in the thymus
Synonyms:exact_synonym: increased thymocyte count
 alt_id: MP:0000326;   MP:0000721;   MP:0001827
 xref: CL:0000893



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increased thymocyte number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta IAGP MGI PMID:23544080 NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509
JBrowse link
G Bax BCL2-associated X protein IAGP MGI PMID:7569956 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2l11 BCL2 like 11 IAGP MGI PMID:19841067 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467
JBrowse link
G Bmf BCL2 modifying factor IAGP MGI PMID:19841067 NCBI chr 2:118,359,238...118,385,240
Ensembl chr 2:118,359,238...118,380,168
JBrowse link
G Cd7 CD7 antigen IAGP MGI PMID:9637484 NCBI chr11:120,927,573...120,930,304
Ensembl chr11:120,927,573...120,930,244
JBrowse link
G Cdk6 cyclin dependent kinase 6 IAGP MGI PMID:21508411 NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008
JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B IAGP MGI PMID:8646780 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
JBrowse link
G Coro1a coronin, actin binding protein 1A IAGP MGI PMID:18836449 NCBI chr 7:126,298,946...126,303,925
Ensembl chr 7:126,298,945...126,306,959
JBrowse link
G Cxadr coxsackie virus and adenovirus receptor IAGP MGI PMID:21674029 NCBI chr16:78,098,114...78,156,673
Ensembl chr16:78,098,377...78,156,662
JBrowse link
G Dusp5 dual specificity phosphatase 5 IAGP MGI PMID:25398911 NCBI chr19:53,517,576...53,530,240
Ensembl chr19:53,517,540...53,530,862
JBrowse link
G E2f1 E2F transcription factor 1 IAGP MGI PMID:8653790 PMID:15470032 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
JBrowse link
G Elavl1 ELAV like RNA binding protein 1 IAGP MGI PMID:19454673 NCBI chr 8:4,334,781...4,375,104
Ensembl chr 8:4,335,382...4,375,413
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha IAGP MGI PMID:10508513 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
JBrowse link
G Gnai2 G protein subunit alpha i2 IAGP MGI PMID:7663509 NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566
JBrowse link
G Hdac1 histone deacetylase 1 IAGP MGI PMID:23287868 NCBI chr 4:129,409,897...129,436,516
Ensembl chr 4:129,409,897...129,436,506
JBrowse link
G Hdac2 histone deacetylase 2 IAGP MGI PMID:23287868 NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885
JBrowse link
G Il7r interleukin 7 receptor IAGP MGI PMID:23267098 NCBI chr15:9,505,880...9,530,270
Ensembl chr15:9,505,874...9,530,262
JBrowse link
G Klf13 Kruppel-like transcription factor 13 IAGP MGI PMID:17442931 NCBI chr 7:63,536,099...63,588,663
Ensembl chr 7:63,536,099...63,588,663
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha IAGP MGI PMID:20696914 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Pag1 phosphoprotein associated with glycosphingolipid microdomains 1 IAGP MGI PMID:16166631 NCBI chr 3:9,752,539...9,898,744
Ensembl chr 3:9,752,539...9,898,739
JBrowse link
G Rag1 recombination activating 1 IAGP MGI PMID:17442925 NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846
JBrowse link
G Rag2 recombination activating gene 2 IAGP MGI PMID:20937703 NCBI chr 2:101,455,057...101,462,873
Ensembl chr 2:101,455,063...101,462,874
JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 IAGP MGI PMID:22761313 NCBI chr 7:45,071,320...45,084,817
Ensembl chr 7:45,071,184...45,087,520
JBrowse link
G Sgpl1 sphingosine phosphate lyase 1 IAGP MGI PMID:23544080 NCBI chr10:60,934,421...60,983,463
Ensembl chr10:60,934,421...60,983,482
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 IAGP MGI PMID:18955569 NCBI chr 9:21,527,377...21,615,526
Ensembl chr 9:21,527,465...21,615,526
JBrowse link
G Stk4 serine/threonine kinase 4 IAGP MGI PMID:19692642 NCBI chr 2:163,916,033...163,997,444
Ensembl chr 2:163,912,242...163,997,444
JBrowse link
G Tbata thymus, brain and testes associated IAGP MGI PMID:20937703 NCBI chr10:61,007,743...61,024,620
Ensembl chr10:61,007,733...61,024,620
JBrowse link
G Tnfrsf25 tumor necrosis factor receptor superfamily, member 25 IAGP MGI PMID:11313471 NCBI chr 4:152,199,985...152,204,568
Ensembl chr 4:152,200,391...152,204,576
JBrowse link
G Tnfrsf8 tumor necrosis factor receptor superfamily, member 8 IAGP MGI PMID:8598042 NCBI chr 4:144,993,702...145,041,734
Ensembl chr 4:144,993,707...145,041,734
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 IAGP MGI PMID:22761313 NCBI chr18:5,591,330...5,775,468
Ensembl chr18:5,591,860...5,775,467
JBrowse link
increased DN1 thymic pro-T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk6 cyclin dependent kinase 6 IAGP MGI PMID:21508411 NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008
JBrowse link
G Dnajc11 DnaJ heat shock protein family (Hsp40) member C11 IAGP MGI PMID:25111180 NCBI chr 4:152,018,177...152,066,416
Ensembl chr 4:152,018,148...152,066,594
JBrowse link
G Foxn1 forkhead box N1 IAGP MGI PMID:22072979 NCBI chr11:78,248,403...78,277,597
Ensembl chr11:78,248,403...78,277,384
JBrowse link
G Hes1 hes family bHLH transcription factor 1 IAGP MGI PMID:21093323 NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614
JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 IAGP MGI PMID:21723201 NCBI chr 3:133,169,438...133,250,882
Ensembl chr 3:133,169,440...133,250,900
JBrowse link
increased DN2 thymocyte number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vav1 vav 1 oncogene IAGP MGI PMID:20009105 NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031
JBrowse link
increased DN3 thymocyte number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd3e CD3 antigen, epsilon polypeptide IAGP MGI PMID:23267019 NCBI chr 9:44,910,033...44,920,961
Ensembl chr 9:44,910,038...44,920,925
JBrowse link
G Cdk6 cyclin dependent kinase 6 IAGP MGI PMID:21508411 NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008
JBrowse link
G Efnb1 ephrin B1 IAGP MGI PMID:21976681 NCBI chr  X:98,179,667...98,192,628
Ensembl chr  X:98,179,736...98,192,597
JBrowse link
G Efnb2 ephrin B2 IAGP MGI PMID:21976681 NCBI chr 8:8,667,235...8,711,242
Ensembl chr 8:8,667,434...8,711,242
JBrowse link
G Nkap NFKB activating protein IAGP MGI PMID:19409814 NCBI chr  X:36,390,416...36,414,399
Ensembl chr  X:36,390,448...36,414,399
JBrowse link
G Pole3 polymerase (DNA directed), epsilon 3 (p17 subunit) IAGP MGI PMID:32553171 NCBI chr 4:62,440,889...62,443,305
Ensembl chr 4:62,440,886...62,443,305
JBrowse link
G Prnp prion protein IAGP MGI PMID:16517717 NCBI chr 2:131,751,848...131,780,356
Ensembl chr 2:131,751,848...131,780,349
JBrowse link
G Ptcra pre T cell antigen receptor alpha IAGP MGI PMID:17555992 PMID:21030681 NCBI chr17:47,066,589...47,074,659
Ensembl chr17:47,066,589...47,074,638
JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IAGP MGI PMID:24068938 NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446
JBrowse link
G Rag2 recombination activating gene 2 IAGP MGI PMID:12433370 PMID:26753883 NCBI chr 2:101,455,057...101,462,873
Ensembl chr 2:101,455,063...101,462,874
JBrowse link
G Rnf168 ring finger protein 168 IAGP MGI PMID:21552324 NCBI chr16:32,096,279...32,120,260
Ensembl chr16:32,096,277...32,120,252
JBrowse link
G Septin9 septin 9 IAGP MGI PMID:23644740 NCBI chr11:117,090,487...117,253,151
Ensembl chr11:117,090,487...117,253,151
JBrowse link
G Syk spleen tyrosine kinase IAGP MGI PMID:22728826 NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828
JBrowse link
G Vav1 vav 1 oncogene IAGP MGI PMID:20009105 NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031
JBrowse link
increased DN4 thymocyte number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tsc22d3 TSC22 domain family, member 3 IAGP MGI PMID:22556341 NCBI chr  X:139,440,277...139,501,257
Ensembl chr  X:139,440,277...139,501,408
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16879
    hematopoietic system phenotype 5514
      abnormal hematopoietic system morphology/development 5051
        abnormal thymus morphology 857
          increased thymocyte number 47
            increased DN1 thymic pro-T cell number 5
            increased DN2 thymocyte number 1
            increased DN3 thymocyte number 14
            increased DN4 thymocyte number 1
Path 2
Term Annotations click to browse term
  mammalian phenotype 16879
    immune system phenotype 5665
      abnormal immune system morphology 4061
        abnormal immune system cell morphology 2825
          abnormal leukocyte morphology 2804
            abnormal mononuclear cell morphology 2259
              abnormal lymphocyte morphology 1828
                abnormal lymphocyte cell number 1691
                  abnormal T cell number 1068
                    increased T cell number 640
                      increased thymocyte number 47
                        increased DN1 thymic pro-T cell number 5
                        increased DN2 thymocyte number 1
                        increased DN3 thymocyte number 14
                        increased DN4 thymocyte number 1
paths to the root