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Gene: Sgpl1 (sphingosine phosphate lyase 1) Mus musculus
Symbol: Sgpl1
Name: sphingosine phosphate lyase 1
Description: ENCODES a protein that exhibits sphinganine-1-phosphate aldolase activity (ortholog); INVOLVED IN androgen metabolic process; estrogen metabolic process; face morphogenesis; PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; ASSOCIATED WITH abnormal blood vessel morphology; abnormal bone marrow morphology; abnormal cell migration; ASSOCIATED WITH nephrotic syndrome type 14 (ortholog); FOUND IN endoplasmic reticulum; INTERACTS WITH 1,2-dichloroethane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI428538; D10Xrf456; mSPL; S1PL; SP-lyase 1; sphingosine-1-phosphate aldolase; sphingosine-1-phosphate lyase 1; Spl; SPL 1
Homo sapiens (human) : SGPL1 (sphingosine-1-phosphate lyase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sgpl1 (sphingosine-1-phosphate lyase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sgpl1 (sphingosine-1-phosphate lyase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SGPL1 (sphingosine-1-phosphate lyase 1)
Canis lupus familiaris (dog) : SGPL1 (sphingosine-1-phosphate lyase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sgpl1 (sphingosine-1-phosphate lyase 1)
Sus scrofa (pig) : SGPL1 (sphingosine-1-phosphate lyase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381061,098,642 - 61,147,684 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371060,561,390 - 60,610,413 (-)NCBIGRCm37mm9NCBIm37
MGSCv361060,493,999 - 60,542,956 (-)NCBImm8
Celera1062,199,269 - 62,248,215 (-)NCBICelera
Cytogenetic Map10 B4NCBI
cM Map1032.14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sgpl1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552269
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.