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Gene: Sgpl1 (sphingosine phosphate lyase 1) Mus musculus
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Symbol: Sgpl1
Name: sphingosine phosphate lyase 1
Description: ENCODES a protein that exhibits sphinganine-1-phosphate aldolase activity (ortholog); INVOLVED IN androgen metabolic process; estrogen metabolic process; face morphogenesis; PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; ASSOCIATED WITH abnormal blood vessel morphology; abnormal bone marrow morphology; abnormal cell migration; ASSOCIATED WITH nephrotic syndrome type 14 (ortholog); FOUND IN endoplasmic reticulum; INTERACTS WITH 1,2-dichloroethane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI428538; D10Xrf456; mSPL; S1PL; SP-lyase 1; sphingosine-1-phosphate aldolase; sphingosine-1-phosphate lyase 1; Spl; SPL 1
Orthologs:
Homo sapiens (human) : SGPL1 (sphingosine-1-phosphate lyase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sgpl1 (sphingosine-1-phosphate lyase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sgpl1 (sphingosine-1-phosphate lyase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SGPL1 (sphingosine-1-phosphate lyase 1)
Canis lupus familiaris (dog) : SGPL1 (sphingosine-1-phosphate lyase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sgpl1 (sphingosine-1-phosphate lyase 1)
Sus scrofa (pig) : SGPL1 (sphingosine-1-phosphate lyase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381061,098,642 - 61,147,684 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371060,561,390 - 60,610,413 (-)NCBIGRCm37mm9NCBIm37
MGSCv361060,493,999 - 60,542,956 (-)NCBImm8
Celera1062,199,269 - 62,248,215 (-)NCBICelera
Cytogenetic Map10 B4NCBI
cM Map1032.14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sgpl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552269
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.