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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased DN3 thymocyte number
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Accession:MP:0010133 term browser browse the term
Definition:increased number of thymocytes that have the cell surface marker phenotype CD4-negative, CD8-negative, CD44-negative, and CD25-positive and expressing the T cell receptor beta-chain in complex with the pre-T cell receptor alpha chain.
Synonyms:exact_synonym: increased DN3 alpha-beta immature T lymphocyte number;   increased DN3 alpha-beta immature T-cell number;   increased DN3 cell number;   increased DN3 immature T cell number;   increased TN3 cell number;   increased TN3 thymocyte number
 xref: CL:0000807


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increased DN3 thymocyte number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd3e CD3 antigen, epsilon polypeptide IAGP MGI PMID:23267019 NCBI chr 9:44,910,033...44,920,961
Ensembl chr 9:44,910,038...44,920,925 		JBrowse link
G Cdk6 cyclin dependent kinase 6 IAGP MGI PMID:21508411 NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008 		JBrowse link
G Efnb1 ephrin B1 IAGP MGI PMID:21976681 NCBI chr  X:98,179,667...98,192,628
Ensembl chr  X:98,179,736...98,192,597 		JBrowse link
G Efnb2 ephrin B2 IAGP MGI PMID:21976681 NCBI chr 8:8,667,235...8,711,242
Ensembl chr 8:8,667,434...8,711,242 		JBrowse link
G Nkap NFKB activating protein IAGP MGI PMID:19409814 NCBI chr  X:36,390,416...36,414,399
Ensembl chr  X:36,390,448...36,414,399 		JBrowse link
G Nudcd3 NudC domain containing 3 IAGP MGI PMID:38787962 NCBI chr11:6,055,705...6,150,190
Ensembl chr11:6,055,691...6,150,415 		JBrowse link
G Pole3 polymerase (DNA directed), epsilon 3 (p17 subunit) IAGP MGI PMID:32553171 NCBI chr 4:62,440,889...62,443,305
Ensembl chr 4:62,440,886...62,443,305 		JBrowse link
G Prnp prion protein IAGP MGI PMID:16517717 NCBI chr 2:131,751,848...131,780,356
Ensembl chr 2:131,751,848...131,780,349 		JBrowse link
G Ptcra pre T cell antigen receptor alpha IAGP MGI PMID:17555992 PMID:21030681 NCBI chr17:47,066,589...47,074,659
Ensembl chr17:47,066,589...47,074,638 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IAGP MGI PMID:24068938 NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Rag2 recombination activating gene 2 IAGP MGI PMID:12433370 PMID:26753883 NCBI chr 2:101,455,057...101,462,873
Ensembl chr 2:101,455,063...101,462,874 		JBrowse link
G Rnf168 ring finger protein 168 IAGP MGI PMID:21552324 NCBI chr16:32,096,279...32,120,260
Ensembl chr16:32,096,277...32,120,252 		JBrowse link
G Septin9 septin 9 IAGP MGI PMID:23644740 NCBI chr11:117,090,487...117,253,151
Ensembl chr11:117,090,487...117,253,151 		JBrowse link
G Syk spleen tyrosine kinase IAGP MGI PMID:22728826 NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828 		JBrowse link
G Vav1 vav 1 oncogene IAGP MGI PMID:20009105 NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16965
    hematopoietic system phenotype 5543
      abnormal hematopoietic system morphology/development 5069
        abnormal thymus morphology 860
          increased thymocyte number 48
            increased DN3 thymocyte number 15
Path 2
Term Annotations click to browse term
  mammalian phenotype 16965
    hematopoietic system phenotype 5543
      abnormal hematopoietic system morphology/development 5069
        abnormal hematopoietic cell morphology 4235
          abnormal blood cell morphology 3179
            abnormal hemopoiesis 1157
              abnormal definitive hematopoiesis 1130
                abnormal leukopoiesis 870
                  abnormal lymphopoiesis 747
                    abnormal T cell differentiation 489
                      abnormal double-negative T cell morphology 200
                        increased double-negative T cell number 122
                          increased DN3 thymocyte number 15
paths to the root