ONTOLOGY REPORT - ANNOTATIONS
Term: nitric oxide biosynthetic process
Accession: GO:0006809
browse the term
Definition: The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.
Synonyms: exact_synonym: nitric oxide anabolism; nitric oxide biosynthesis; nitric oxide formation; nitric oxide synthesis
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Acp5
acid phosphatase 5, tartrate resistant
acts_upstream_of
ISO
(PMID:11168643)
MGI
PMID:11168643
NCBI chrNW_004955495:2,418,113...2,421,181
Ensembl chrNW_004955495:2,418,364...2,421,538
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Cav1
caveolin 1
acts_upstream_of
ISO
(PMID:12388077)
MGI
PMID:12388077
NCBI chrNW_004955432:22,258,262...22,292,403
Ensembl chrNW_004955432:22,258,250...22,292,403
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Ifng
interferon gamma
acts_upstream_of
ISO
(PMID:11168643)
MGI
PMID:11168643
NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045
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LOC102009223
cytochrome P450 1B1
involved_in
ISO
(MGI:4431324|PMID:20032512)
UniProt
PMID:20032512
MGI:4431324
NCBI chrNW_004955441:5,803,397...5,812,131
Ensembl chrNW_004955441:5,803,032...5,812,131
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LOC102012303
NADH-cytochrome b5 reductase 3
involved_in
ISO
(PMID:24500710)
FlyBase
PMID:24500710
NCBI chrNW_004955413:27,971,140...27,979,905
Ensembl chrNW_004955413:27,969,949...27,979,909
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LOC102026979
cytochrome b5 type B
involved_in
ISO
(PMID:24500710)
FlyBase
PMID:24500710
NCBI chrNW_004955484:7,239,364...7,270,639
Ensembl chrNW_004955484:7,237,906...7,271,123
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Nos1
nitric oxide synthase 1
involved_in
ISO
(MGI:3807771|PMID:7545544), (MGI:5582183|PMID:11591728) PMID:1383204
RGD BHF-UCL
PMID:1383204 PMID:7545544 PMID:11591728 PMID:14966111
MGI:3807771 MGI:5582183 RGD:1358520 RGD:8553334
NCBI chrNW_004955455:13,797,557...13,978,402
Ensembl chrNW_004955455:13,797,545...13,972,566
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Nos2
nitric oxide synthase 2
involved_in
ISO
(MGI:3807769|PMID:9271491), (MGI:3807772|PMID:1383204) (PMID:7504305), (PMID:7682706)
RGD BHF-UCL UniProt
PMID:1383204 PMID:7504305 PMID:7682706 PMID:9271491 PMID:12826065 PMID:16172396 More...
MGI:3807769 MGI:3807772 RGD:1358527 RGD:1580262
NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961
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Nos3
nitric oxide synthase 3
acts_upstream_of_or_within involved_in
ISO
(PMID:15647265) (PMID:1378832), (PMID:7488039)
RGD MGI BHF-UCL
PMID:1378832 PMID:7488039 PMID:12388111 PMID:15647265 PMID:16344378
RGD:628542 RGD:7794722
NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814
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P2rx4
purinergic receptor P2X 4
acts_upstream_of_or_within
ISO
(PMID:16327800)
MGI
PMID:16327800
NCBI chrNW_004955482:7,031,874...7,039,026
Ensembl chrNW_004955482:7,031,874...7,039,220
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Rora
RAR related orphan receptor A
acts_upstream_of_or_within
ISO
(PMID:7518067)
MGI
PMID:7518067
NCBI chrNW_004955450:14,262,199...14,434,611
Ensembl chrNW_004955450:14,262,190...14,425,233
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Slc7a2
solute carrier family 7 member 2
acts_upstream_of_or_within
ISO
(PMID:12675924)
MGI
PMID:12675924
NCBI chrNW_004955552:2,117,972...2,141,144
Ensembl chrNW_004955552:2,117,755...2,141,231
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Slc7a6
solute carrier family 7 member 6
involved_in
ISO
PMID:26448619
UniProt
PMID:26448619
RGD:11531816
NCBI chrNW_004955484:8,335,508...8,383,814
Ensembl chrNW_004955484:8,349,622...8,383,475
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Spr
sepiapterin reductase
involved_in
ISO
(PMID:15197144)
UniProt
PMID:15197144
NCBI chrNW_004955424:12,711,064...12,716,000
Ensembl chrNW_004955424:12,711,064...12,716,000
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Ticam1
toll like receptor adaptor molecule 1
acts_upstream_of
ISO
(PMID:12872135)
MGI
PMID:12872135
NCBI chrNW_004955495:4,197,083...4,204,999
Ensembl chrNW_004955495:4,202,372...4,204,513
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Tlr2
toll like receptor 2
acts_upstream_of
ISO
(PMID:10549626), (PMID:16239543)
MGI
PMID:10549626 PMID:16239543
NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258
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Tlr4
toll like receptor 4
acts_upstream_of
ISO
(PMID:10549626)
MGI
PMID:10549626
NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
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Acp5
acid phosphatase 5, tartrate resistant
acts_upstream_of_or_within
ISO
(PMID:11168643)
MGI
PMID:11168643
NCBI chrNW_004955495:2,418,113...2,421,181
Ensembl chrNW_004955495:2,418,364...2,421,538
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Atp2b4
ATPase plasma membrane Ca2+ transporting 4
involved_in
ISO
(PMID:11591728), (PMID:17242280), (PMID:19278978)
BHF-UCL
PMID:11591728 PMID:17242280 PMID:19278978
NCBI chrNW_004955406:39,552,034...39,645,694
Ensembl chrNW_004955406:39,552,019...39,645,694
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Cav1
caveolin 1
acts_upstream_of_or_within
ISO
(PMID:12388077)
MGI
PMID:12388077
NCBI chrNW_004955432:22,258,262...22,292,403
Ensembl chrNW_004955432:22,258,250...22,292,403
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Dynll1
dynein light chain LC8-type 1
acts_upstream_of_or_within involved_in
ISO
PMID:8864115
MGI UniProt
PMID:8864115
RGD:633683
NCBI chrNW_004955455:11,148,041...11,150,860
Ensembl chrNW_004955455:11,148,047...11,150,859
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Epor
erythropoietin receptor
ISO
RGD
PMID:10489101
RGD:11041656
NCBI chrNW_004955495:2,293,587...2,299,302
Ensembl chrNW_004955495:2,293,540...2,298,715
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Gla
galactosidase alpha
involved_in
ISO
(MGI:3624267|PMID:15668341)
UniProt
PMID:15668341
MGI:3624267
NCBI chrNW_004955503:7,526,077...7,535,817
Ensembl chrNW_004955503:7,521,930...7,535,817
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Il10
interleukin 10
ISO
RGD
PMID:17017555
RGD:1598631
NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
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Il4
interleukin 4
ISO
RGD
PMID:18182309
RGD:2317291
NCBI chrNW_004955408:4,058,052...4,065,999
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Khsrp
KH-type splicing regulatory protein
involved_in
ISO
(PMID:16126846)
UniProt
PMID:16126846
NCBI chrNW_004955495:3,183,083...3,194,356
Ensembl chrNW_004955495:3,183,179...3,193,376
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Oprm1
opioid receptor mu 1
involved_in
ISO
(PMID:20525224)
UniProt
PMID:20525224
NCBI chrNW_004955439:7,870,563...7,923,817
Ensembl chrNW_004955439:7,757,569...7,923,817
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Prl
prolactin
involved_in
ISO
(PMID:24530842)
AgBase
PMID:24530842
NCBI chrNW_004955483:4,495,257...4,503,377
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Ptgis
prostaglandin I2 synthase
involved_in
ISO
(PMID:20159982)
UniProt
PMID:20159982
NCBI chrNW_004955445:8,624,228...8,663,385
Ensembl chrNW_004955445:8,623,430...8,677,658
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Rgn
regucalcin
ISO
RGD
PMID:12686401
RGD:9590175
NCBI chrNW_004955516:958,416...978,829
Ensembl chrNW_004955516:955,680...978,910
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Rock2
Rho associated coiled-coil containing protein kinase 2
involved_in
ISO
(PMID:29353861) (MGI:6271078|PMID:29353861)
ARUK-UCL
PMID:29353861
MGI:6271078
NCBI chrNW_004955487:5,856,190...5,972,408
Ensembl chrNW_004955487:5,859,204...5,972,401
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Sirpa
signal regulatory protein alpha
involved_in
ISO
(MGI:3760575|PMID:17954568)
ARUK-UCL
PMID:17954568
MGI:3760575
NCBI chrNW_004955415:13,030,752...13,072,735
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Tspo
translocator protein
ISO
RGD
PMID:14678758
RGD:2317158
NCBI chrNW_004955413:28,309,105...28,315,075
Ensembl chrNW_004955413:28,308,658...28,315,075
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Wdr35
WD repeat domain 35
ISO
RGD
PMID:18671723
RGD:11553926
NCBI chrNW_004955469:2,484,972...2,546,562
Ensembl chrNW_004955469:2,482,353...2,546,578
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Zc3h12a
zinc finger CCCH-type containing 12A
involved_in
ISO
(PMID:18178554) (MGI:5142149|PMID:21616078)
BHF-UCL UniProt
PMID:18178554 PMID:21616078
MGI:5142149
NCBI chrNW_004955452:15,306,398...15,314,959
Ensembl chrNW_004955452:15,305,775...15,314,959
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Agt
angiotensinogen
ISO
RGD
PMID:17616753
RGD:8548892
NCBI chrNW_004955492:7,863,662...7,874,863
Ensembl chrNW_004955492:7,866,833...7,873,357
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Agxt2
alanine--glyoxylate aminotransferase 2
involved_in
ISO
(PMID:20018850)
BHF-UCL
PMID:20018850
NCBI chrNW_004955426:20,102,368...20,142,596
Ensembl chrNW_004955426:20,101,620...20,142,620
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Aif1
allograft inflammatory factor 1
ISO
RGD
PMID:16157606
RGD:2313017
NCBI chrNW_004955437:157,509...158,919
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Akt1
AKT serine/threonine kinase 1
involved_in
ISO
(PMID:10376603)
BHF-UCL
PMID:10376603
NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904
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Akt2
AKT serine/threonine kinase 2
ISO
RGD
PMID:18335029
RGD:2313325
NCBI chrNW_004955578:950,258...1,004,438
Ensembl chrNW_004955578:967,593...1,004,438
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Apoe
apolipoprotein E
involved_in
ISO
(PMID:8995232)
BHF-UCL
PMID:8995232
NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888
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App
amyloid beta precursor protein
involved_in
ISO
(PMID:20037584)
ARUK-UCL
PMID:20037584
NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268
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Asl
argininosuccinate lyase
involved_in
ISO
(PMID:22081021) (MGI:5305859|PMID:22081021)
UniProt
PMID:22081021
MGI:5305859
NCBI chrNW_004955456:8,409,767...8,419,915
Ensembl chrNW_004955456:8,411,220...8,416,992
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Ass1
argininosuccinate synthase 1
involved_in
ISO
(PMID:21106532)
BHF-UCL
PMID:21106532
NCBI chrNW_004955513:443,372...485,190
Ensembl chrNW_004955513:445,462...485,190
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Cd36
CD36 molecule (CD36 blood group)
involved_in
ISO
(MGI:4438693|PMID:20037584)
ARUK-UCL
PMID:20037584
MGI:4438693
NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313
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Clu
clusterin
involved_in
ISO
(PMID:15857407)
Alzheimers_University_of_Toronto
PMID:15857407
NCBI chrNW_004955403:50,160,598...50,175,876
Ensembl chrNW_004955403:50,160,598...50,175,876
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Ddah1
dimethylarginine dimethylaminohydrolase 1
involved_in
ISO
(MGI:5315329|PMID:21493890)
RGD BHF-UCL
PMID:12237779 PMID:21493890
MGI:5315329 RGD:727432
NCBI chrNW_004955423:8,637,116...8,673,881
Ensembl chrNW_004955423:8,636,756...8,676,790
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Dnm2
dynamin 2
ISO
RGD
PMID:16973909
RGD:9685181
NCBI chrNW_004955495:1,860,644...1,934,589
Ensembl chrNW_004955495:1,860,644...1,934,818
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Esr1
estrogen receptor 1
involved_in
ISO
(PMID:21937726)
UniProt
PMID:21937726
NCBI chrNW_004955439:9,588,631...9,953,606
Ensembl chrNW_004955439:9,588,201...9,963,353
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Hrh1
histamine receptor H1
ISO
RGD
PMID:12419527
RGD:727463
NCBI chrNW_004955429:14,022,332...14,069,931
Ensembl chrNW_004955429:14,067,405...14,068,853
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Hsp90aa1
heat shock protein 90 alpha family class A member 1
involved_in
ISO
(MGI:3687888|PMID:12855682)
UniProt
PMID:12855682
MGI:3687888
NCBI chrNW_004955538:1,469,544...1,475,010
Ensembl chrNW_004955538:1,469,544...1,475,019
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Icam1
intercellular adhesion molecule 1
ISO
RGD
PMID:9062344
RGD:1600239
NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
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Ifng
interferon gamma
involved_in acts_upstream_of_or_within
ISO
(PMID:8383325) (PMID:11168643)
BHF-UCL MGI
PMID:8383325 PMID:11168643
NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045
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Il1b
interleukin 1 beta
involved_in
ISO
(PMID:8383325)
BHF-UCL
PMID:8383325
NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
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Il6
interleukin 6
ISO
RGD
PMID:15845578
RGD:2306941
NCBI chrNW_004955410:25,079,835...25,084,390
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Insr
insulin receptor
involved_in
ISO
(PMID:10747347)
BHF-UCL
PMID:10747347
NCBI chrNW_004955563:1,867,400...2,011,845
Ensembl chrNW_004955563:1,867,400...2,009,149
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Itgb2
integrin subunit beta 2
ISO
RGD
PMID:9062344
RGD:1600239
NCBI chrNW_004955407:41,779,849...41,805,637
Ensembl chrNW_004955407:41,777,777...41,800,201
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Jak2
Janus kinase 2
ISO
RGD
PMID:12595539
RGD:1641934
NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208
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Klf4
KLF transcription factor 4
involved_in
ISO
(PMID:22430140)
BHF-UCL
PMID:22430140
NCBI chrNW_004955419:19,280,311...19,284,097
Ensembl chrNW_004955419:19,280,235...19,285,174
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Mapk9
mitogen-activated protein kinase 9
ISO
RGD
PMID:10593906
RGD:2304240
NCBI chrNW_004955408:391,094...430,638
Ensembl chrNW_004955408:391,094...430,981
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Mtor
mechanistic target of rapamycin kinase
ISO
RGD
PMID:19576187
RGD:10041012
NCBI chrNW_004955486:2,487,642...2,599,694
Ensembl chrNW_004955486:2,487,642...2,599,694
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Nfatc3
nuclear factor of activated T cells 3
involved_in
ISO
(MGI:6871969|PMID:24970700)
UniProt
PMID:24970700
MGI:6871969
NCBI chrNW_004955484:8,433,765...8,558,005
Ensembl chrNW_004955484:8,436,330...8,526,680
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Oprm1
opioid receptor mu 1
involved_in
ISO
(PMID:20214800)
UniProt
PMID:20214800
NCBI chrNW_004955439:7,870,563...7,923,817
Ensembl chrNW_004955439:7,757,569...7,923,817
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Pik3cb
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
acts_upstream_of_or_within
ISO
(PMID:18558630)
BHF-UCL
PMID:18558630
NCBI chrNW_004955501:251,829...381,255
Ensembl chrNW_004955501:259,645...379,909
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Pkd2
polycystin 2, transient receptor potential cation channel
involved_in
ISO
(PMID:19265036) (MGI:5315687|PMID:19265036)
BHF-UCL
PMID:19265036
MGI:5315687
NCBI chrNW_004955474:1,831,221...1,868,170
Ensembl chrNW_004955474:1,833,701...1,868,817
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Ptgs2
prostaglandin-endoperoxide synthase 2
involved_in
ISO
PMID:9630216
BHF-UCL
PMID:9630216
RGD:5135054
NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171
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Ptk2b
protein tyrosine kinase 2 beta
ISO
RGD
PMID:21926342
RGD:10041069
NCBI chrNW_004955403:49,856,056...49,970,800
Ensembl chrNW_004955403:49,855,541...49,973,225
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Ptx3
pentraxin 3
acts_upstream_of_or_within
ISO
(PMID:14726497)
MGI
PMID:14726497
NCBI chrNW_004955448:8,366,795...8,373,010
Ensembl chrNW_004955448:8,366,925...8,372,411
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Smad3
SMAD family member 3
involved_in
ISO
(PMID:27038547)
BHF-UCL
PMID:27038547
RGD:11535100
NCBI chrNW_004955450:8,747,651...8,842,003
Ensembl chrNW_004955450:8,747,651...8,842,136
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Smpd3
sphingomyelin phosphodiesterase 3
ISO
RGD
PMID:14720208
RGD:10042970
NCBI chrNW_004955484:8,207,686...8,298,164
Ensembl chrNW_004955484:8,272,572...8,298,144
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Sod2
superoxide dismutase 2
acts_upstream_of_or_within
ISO
(PMID:15637112)
MGI
PMID:15637112
NCBI chrNW_004955439:21,209,101...21,223,538
Ensembl chrNW_004955439:21,209,101...21,224,163
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Ticam1
toll like receptor adaptor molecule 1
acts_upstream_of_or_within
ISO
(PMID:12872135)
MGI
PMID:12872135
NCBI chrNW_004955495:4,197,083...4,204,999
Ensembl chrNW_004955495:4,202,372...4,204,513
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Tlr2
toll like receptor 2
acts_upstream_of_or_within
ISO
(PMID:10549626), (PMID:16239543)
MGI
PMID:10549626 PMID:16239543
NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258
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Tlr4
toll like receptor 4
involved_in acts_upstream_of_or_within
ISO
(MGI:4438693|PMID:20037584) (PMID:10549626)
ARUK-UCL MGI
PMID:10549626 PMID:20037584
MGI:4438693
NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
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Tlr5
toll like receptor 5
ISO
RGD
PMID:16973131
RGD:1643119
NCBI chrNW_004955520:1,544,840...1,562,081
Ensembl chrNW_004955520:1,556,523...1,559,093
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Tlr6
toll like receptor 6
involved_in
ISO
(MGI:4438693|PMID:20037584)
ARUK-UCL
PMID:20037584
MGI:4438693
NCBI chrNW_004955443:8,401,461...8,427,175
Ensembl chrNW_004955443:8,422,534...8,424,942
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Tnf
tumor necrosis factor
involved_in
ISO
(PMID:8383325)
BHF-UCL
PMID:8383325
NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
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Trpv1
transient receptor potential cation channel subfamily V member 1
ISO
RGD
PMID:16081483
RGD:2317115
NCBI chrNW_004955467:13,221,391...13,239,089
Ensembl chrNW_004955467:13,221,391...13,239,089
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Acvr2a
activin A receptor type 2A
acts_upstream_of_or_within
ISO
(PMID:16093358)
MGI
PMID:16093358
NCBI chrNW_004955440:13,849,926...13,931,374
Ensembl chrNW_004955440:13,849,926...13,931,374
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Arg2
arginase 2
ISO
RGD
PMID:11829529
RGD:634667
NCBI chrNW_004955466:2,549,557...2,577,060
Ensembl chrNW_004955466:2,549,557...2,577,060
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Cd47
CD47 molecule
involved_in
ISO
(MGI:6201986|PMID:16055727)
ARUK-UCL
PMID:16055727
MGI:6201986
NCBI chrNW_004955427:8,704,519...8,740,962
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Cx3cr1
C-X3-C motif chemokine receptor 1
involved_in
ISO
(MGI:6162390|PMID:23499256)
ARUK-UCL
PMID:23499256
MGI:6162390
NCBI chrNW_004955427:24,691,206...24,705,599
Ensembl chrNW_004955427:24,701,073...24,707,230
G
Igf1
insulin like growth factor 1
acts_upstream_of_or_within
ISO
(PMID:21677284)
MGI
PMID:21677284
NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
G
Jak2
Janus kinase 2
involved_in
ISO
PMID:16055727
ARUK-UCL
PMID:16055727
RGD:13792550
NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208
G
Nosip
nitric oxide synthase interacting protein
involved_in
ISO
(PMID:15548660)
UniProt
PMID:15548660
NCBI chrNW_004955559:1,287,155...1,300,550
Ensembl chrNW_004955559:1,297,340...1,300,507
G
Rac1
Rac family small GTPase 1
involved_in
ISO
PMID:16055727
ARUK-UCL
PMID:16055727
RGD:13792550
NCBI chrNW_004955460:13,270,159...13,295,562
Ensembl chrNW_004955460:13,270,159...13,311,351
G
Sirpa
signal regulatory protein alpha
involved_in
ISO
PMID:16055727
ARUK-UCL
PMID:16055727
RGD:13792550
NCBI chrNW_004955415:13,030,752...13,072,735
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all