Spr (sepiapterin reductase) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Spr (sepiapterin reductase) Chinchilla lanigera
Analyze
Symbol: Spr
Name: sepiapterin reductase
RGD ID: 8787248
Description: ENCODES a protein that exhibits protein homodimerization activity (ortholog); sepiapterin reductase activity (ortholog); INVOLVED IN cell morphogenesis involved in neuron differentiation (ortholog); dopamine metabolic process (ortholog); L-phenylalanine metabolic process (ortholog); PARTICIPATES IN dopa responsive dystonia pathway; Segawa syndrome pathway; ASSOCIATED WITH COVID-19 (ortholog); Developmental Disabilities (ortholog); dystonia (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542412,711,064 - 12,716,000 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542412,711,064 - 12,716,000 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Spr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542412,711,064 - 12,716,000 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542412,711,064 - 12,716,000 (-)NCBIChiLan1.0ChiLan1.0
SPR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl272,887,382 - 72,892,158 (+)EnsemblGRCh38hg38GRCh38
GRCh38272,887,408 - 72,892,158 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37273,114,512 - 73,119,289 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36272,968,056 - 72,972,794 (+)NCBINCBI36hg18NCBI36
Build 34273,026,202 - 73,030,941NCBI
Celera272,965,357 - 72,970,134 (+)NCBI
Cytogenetic Map2p13.2NCBI
HuRef272,850,110 - 72,854,887 (+)NCBIHuRef
CHM1_1273,044,688 - 73,049,465 (+)NCBICHM1_1
Spr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39685,110,662 - 85,114,746 (-)NCBIGRCm39mm39
GRCm38685,133,680 - 85,137,764 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl685,130,176 - 85,137,766 (-)EnsemblGRCm38mm10GRCm38
MGSCv37685,083,674 - 85,087,758 (-)NCBIGRCm37mm9NCBIm37
MGSCv36685,099,343 - 85,103,476 (-)NCBImm8
Celera687,104,831 - 87,108,907 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map637.15NCBI
Spr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04116,912,343 - 116,916,073 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4116,912,351 - 116,916,236 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04181,492,882 - 181,496,612 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44119,365,578 - 119,369,308 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14119,610,075 - 119,613,765 (-)NCBI
Celera4106,655,853 - 106,659,586 (-)NCBICelera
Cytogenetic Map4q34NCBI
SPR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A74,433,056 - 74,438,105 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A74,433,056 - 74,438,105 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A72,939,621 - 72,944,669 (+)NCBIMhudiblu_PPA_v0panPan3
SPR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1749,950,800 - 49,957,417 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11749,950,192 - 49,957,455 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Spr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493649116,693,940 - 16,699,040 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl369,887,386 - 69,894,758 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1369,889,448 - 69,894,747 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2373,090,291 - 73,095,590 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SPR
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl1434,275,289 - 34,280,786 (-)Ensembl
ChlSab1.11434,275,292 - 34,280,579 (-)NCBI
Spr
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624762729,294 - 734,761 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000025444   ⟹   ENSCLAP00000025198
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542412,711,064 - 12,716,000 (-)Ensembl
RefSeq Acc Id: XM_005385808   ⟹   XP_005385865
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542412,711,064 - 12,716,000 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005385865 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005385865   ⟸   XM_005385808
- Sequence:
RefSeq Acc Id: ENSCLAP00000025198   ⟸   ENSCLAT00000025444


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000017303 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000025198 ENTREZGENE
Ensembl Transcript ENSCLAT00000025444 ENTREZGENE
NCBI Gene Spr ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-08 Spr  sepiapterin reductase    sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)  Symbol and/or name change 5135510 APPROVED