Rgn (regucalcin) - Rat Genome Database

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Gene: Rgn (regucalcin) Chinchilla lanigera
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Symbol: Rgn
Name: regucalcin
RGD ID: 8954913
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); gluconolactonase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN intracellular calcium ion homeostasis (ortholog); kidney development (ortholog); L-ascorbic acid biosynthetic process (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Chemical and Drug Induced Liver Injury (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955516955,680 - 978,910 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955516958,416 - 978,829 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
intracellular calcium ion homeostasis  (ISO)
kidney development  (ISO)
L-ascorbic acid biosynthetic process  (ISO)
liver development  (ISO)
liver regeneration  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of bone development  (ISO)
negative regulation of calcium-dependent ATPase activity  (ISO)
negative regulation of cyclic-nucleotide phosphodiesterase activity  (ISO)
negative regulation of DNA biosynthetic process  (ISO)
negative regulation of DNA catabolic process  (ISO)
negative regulation of epithelial cell proliferation  (ISO)
negative regulation of flagellated sperm motility  (ISO)
negative regulation of GTPase activity  (ISO)
negative regulation of macromolecule biosynthetic process  (ISO)
negative regulation of nitric oxide biosynthetic process  (ISO)
negative regulation of protein kinase activity  (ISO)
negative regulation of protein phosphorylation  (ISO)
negative regulation of RNA biosynthetic process  (ISO)
positive regulation of ATP-dependent activity  (ISO)
positive regulation of ATPase-coupled calcium transmembrane transporter activity  (ISO)
positive regulation of fatty acid biosynthetic process  (ISO)
positive regulation of glucose metabolic process  (ISO)
positive regulation of GTPase activity  (ISO)
positive regulation of phosphatase activity  (ISO)
positive regulation of proteolysis involved in protein catabolic process  (ISO)
positive regulation of superoxide dismutase activity  (ISO)
positive regulation of triglyceride biosynthetic process  (ISO)
regulation of calcium-mediated signaling  (ISO)
spermatogenesis  (ISO)

Cellular Component
cytoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rgn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955516955,680 - 978,910 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955516958,416 - 978,829 (-)NCBIChiLan1.0ChiLan1.0
RGN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X47,078,443 - 47,093,313 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX47,078,355 - 47,093,314 (+)EnsemblGRCh38hg38GRCh38
GRCh37X46,937,842 - 46,952,712 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X46,822,719 - 46,837,656 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X46,696,510 - 46,708,966NCBI
CeleraX51,129,720 - 51,148,035 (+)NCBICelera
Cytogenetic MapXp11.3NCBI
HuRefX44,651,176 - 44,667,384 (+)NCBIHuRef
CHM1_1X46,969,564 - 46,984,507 (+)NCBICHM1_1
T2T-CHM13v2.0X46,485,437 - 46,503,065 (+)NCBIT2T-CHM13v2.0
Rgn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X20,413,980 - 20,428,328 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX20,416,026 - 20,428,328 (+)EnsemblGRCm39 Ensembl
GRCm38X20,549,766 - 20,562,089 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX20,549,787 - 20,562,089 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X20,126,944 - 20,139,213 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X19,706,777 - 19,719,046 (+)NCBIMGSCv36mm8
CeleraX18,681,357 - 18,693,626 (+)NCBICelera
Cytogenetic MapXA1.3NCBI
cM MapX16.04NCBI
Rgn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X4,172,537 - 4,190,112 (-)NCBIGRCr8
mRatBN7.2X1,619,030 - 1,634,456 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX1,619,032 - 1,634,450 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX1,653,062 - 1,668,461 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X5,128,761 - 5,144,164 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X1,444,046 - 1,459,469 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X1,833,484 - 1,848,904 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX1,833,492 - 1,848,904 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X2,626,525 - 2,641,949 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X13,037,171 - 13,052,846NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX2,182,952 - 2,198,371 (-)NCBICelera
Cytogenetic MapXq11NCBI
RGN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X48,703,675 - 48,720,753 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X48,707,048 - 48,724,130 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X39,513,135 - 39,530,188 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X47,371,225 - 47,388,881 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX47,371,226 - 47,388,881 (+)Ensemblpanpan1.1panPan2
RGN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X40,697,292 - 40,715,491 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX40,698,768 - 40,715,490 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX15,074,578 - 15,090,960 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X40,818,343 - 40,849,916 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX40,833,166 - 40,849,918 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X40,806,174 - 40,837,694 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X40,793,810 - 40,825,378 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X40,886,864 - 40,918,439 (+)NCBIUU_Cfam_GSD_1.0
Rgn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X33,032,122 - 33,050,817 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650212,872,824 - 12,891,506 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650212,872,938 - 12,891,270 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX41,726,526 - 41,749,381 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X41,725,660 - 41,749,736 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X46,902,494 - 46,926,414 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RGN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X44,282,825 - 44,299,027 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX44,285,601 - 44,299,258 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660769,539,184 - 9,555,388 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rgn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248873,883,213 - 3,899,277 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248873,881,624 - 3,900,144 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Sequence


Ensembl Acc Id: ENSCLAT00000001485   ⟹   ENSCLAP00000001442
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955516955,680 - 978,910 (-)Ensembl
RefSeq Acc Id: XM_005408970   ⟹   XP_005409027
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955516958,416 - 976,922 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005408971   ⟹   XP_005409028
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955516958,416 - 978,829 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005409027 (Get FASTA)   NCBI Sequence Viewer  
  XP_005409028 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000001442
  ENSCLAP00000001442.1
RefSeq Acc Id: XP_005409028   ⟸   XM_005408971
- UniProtKB: A0A8C2UM76 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005409027   ⟸   XM_005408970
- UniProtKB: A0A8C2UM76 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000001442   ⟸   ENSCLAT00000001485

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001089 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000001485 ENTREZGENE
  ENSCLAT00000001485.1 UniProtKB/TrEMBL
Gene3D-CATH 2.120.10.30 UniProtKB/TrEMBL
InterPro 6-blade_b-propeller_TolB-like UniProtKB/TrEMBL
  Regucalcin UniProtKB/TrEMBL
  SGL UniProtKB/TrEMBL
  SMP-30 UniProtKB/TrEMBL
NCBI Gene Rgn ENTREZGENE
PANTHER REGUCALCIN UniProtKB/TrEMBL
  REGUCALCIN UniProtKB/TrEMBL
Pfam SGL UniProtKB/TrEMBL
PRINTS REGUCALCIN UniProtKB/TrEMBL
  SMP30FAMILY UniProtKB/TrEMBL
Superfamily-SCOP Calcium-dependent phosphotriesterase UniProtKB/TrEMBL
UniProt A0A8C2UM76 ENTREZGENE, UniProtKB/TrEMBL