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ONTOLOGY REPORT - ANNOTATIONS

Term:endochondral ossification
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Accession:GO:0001958 term browser browse the term
Definition:Replacement ossification wherein bone tissue replaces cartilage.
Synonyms:xref: Wikipedia:Endochondral_ossification


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endochondral ossification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, liver/bone/kidney acts_upstream_of_or_within IMP (PMID:20684022) MGI PMID:20684022 NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IMP (MGI:4418577|PMID:20059955) UniProt PMID:20059955 MGI:4418577 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126 		JBrowse link
G Bmp6 bone morphogenetic protein 6 acts_upstream_of_or_within IMP (PMID:9664685) MGI PMID:9664685 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278 		JBrowse link
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 acts_upstream_of_or_within IMP (PMID:18539921) MGI PMID:18539921 NCBI chr 4:4,762,484...4,793,306
Ensembl chr 4:4,762,484...4,793,355 		JBrowse link
G Cbs cystathionine beta-synthase acts_upstream_of_or_within IMP (PMID:15622513) MGI PMID:15622513 NCBI chr17:31,831,602...31,856,170
Ensembl chr17:31,827,868...31,856,212 		JBrowse link
G Col10a1 collagen, type X, alpha 1 involved_in ISO RGD
MGI		 PMID:10853827 GO_REF:0000096 MGI:4417868 RGD:704421 NCBI chr10:34,265,977...34,273,081
Ensembl chr10:34,265,977...34,273,081 		JBrowse link
G Col13a1 collagen, type XIII, alpha 1 involved_in IEP (MGI:2157681|PMID:11470398) UniProt PMID:11470398 MGI:2157681 NCBI chr10:61,674,013...61,814,985
Ensembl chr10:61,674,015...61,814,887 		JBrowse link
G Col1a1 collagen, type I, alpha 1 acts_upstream_of_or_within IMP (PMID:8130375) MGI PMID:8130375 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868 		JBrowse link
G Col2a1 collagen, type II, alpha 1 acts_upstream_of_or_within IMP (PMID:10100048) MGI PMID:10100048 NCBI chr15:97,873,483...97,902,525
Ensembl chr15:97,873,483...97,902,576 		JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 acts_upstream_of_or_within IMP (PMID:21148564) MGI PMID:21148564 NCBI chr 8:68,809,433...69,188,270
Ensembl chr 8:68,809,433...69,187,798 		JBrowse link
G Cst5 cystatin D involved_in IMP (PMID:16680148) MGI PMID:16680148 NCBI chr 2:149,247,242...149,252,217
Ensembl chr 2:149,246,977...149,252,213 		JBrowse link
G Dlx5 distal-less homeobox 5 involved_in IMP (MGI:4413604|PMID:19956613) UniProt PMID:19956613 MGI:4413604 NCBI chr 6:6,877,801...6,882,068
Ensembl chr 6:6,877,805...6,882,085 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in IMP (PMID:24770645) MGI PMID:24770645 NCBI chr10:24,513,812...24,588,057
Ensembl chr10:24,513,812...24,588,057 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within IMP (PMID:21185280), (PMID:23958822) MGI PMID:21185280 PMID:23958822 NCBI chr15:52,931,657...53,209,579
Ensembl chr15:52,927,434...53,209,555 		JBrowse link
G Fgf18 fibroblast growth factor 18 acts_upstream_of_or_within IMP (PMID:17014841) MGI PMID:17014841 NCBI chr11:33,066,970...33,097,400
Ensembl chr11:33,067,430...33,097,400 		JBrowse link
G Foxc1 forkhead box C1 involved_in IMP (MGI:5641778|PMID:25808752) UniProt PMID:25808752 MGI:5641778 NCBI chr13:31,990,629...31,994,618
Ensembl chr13:31,990,616...31,996,459 		JBrowse link
G Gnas GNAS complex locus acts_upstream_of_or_within IMP (PMID:15797856) MGI PMID:15797856 NCBI chr 2:174,126,113...174,188,537
Ensembl chr 2:174,126,113...174,188,537 		JBrowse link
G Hspg2 perlecan (heparan sulfate proteoglycan 2) acts_upstream_of_or_within IMP (PMID:10579729) MGI PMID:10579729 NCBI chr 4:137,196,062...137,297,941
Ensembl chr 4:137,196,080...137,297,941 		JBrowse link
G Ift80 intraflagellar transport 80 acts_upstream_of_or_within IMP (PMID:26098911) MGI PMID:26098911 NCBI chr 3:68,799,832...68,911,939
Ensembl chr 3:68,799,832...68,911,892 		JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:101,471,839...101,487,419
Ensembl chr 7:101,471,839...101,487,436 		JBrowse link
G Mef2c myocyte enhancer factor 2C acts_upstream_of_or_within IMP
IGI		 (PMID:17336904) MGI PMID:17336904 NCBI chr13:83,652,136...83,815,197
Ensembl chr13:83,652,153...83,815,199 		JBrowse link
G Mef2d myocyte enhancer factor 2D acts_upstream_of_or_within IGI (PMID:17336904) MGI PMID:17336904 NCBI chr 3:88,049,248...88,079,398
Ensembl chr 3:88,049,679...88,079,393 		JBrowse link
G Mmp13 matrix metallopeptidase 13 involved_in IMP
ISO		 (MGI:3771509|PMID:17987127) UniProt
RGD		 PMID:10646117 PMID:17987127 MGI:3771509 RGD:10043159 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331 		JBrowse link
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) acts_upstream_of_or_within IGI (PMID:18022611) MGI PMID:18022611 NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821 		JBrowse link
G Mmp16 matrix metallopeptidase 16 acts_upstream_of_or_within IGI (PMID:18022611) MGI PMID:18022611 NCBI chr 4:17,853,072...18,117,479
Ensembl chr 4:17,852,893...18,119,145 		JBrowse link
G Nab1 Ngfi-A binding protein 1 acts_upstream_of_or_within IGI (PMID:16136673) MGI PMID:16136673 NCBI chr 1:52,494,146...52,539,553
Ensembl chr 1:52,496,453...52,539,838 		JBrowse link
G Nab2 Ngfi-A binding protein 2 acts_upstream_of_or_within IGI (PMID:16136673) MGI PMID:16136673 NCBI chr10:127,496,787...127,502,572
Ensembl chr10:127,496,787...127,504,437 		JBrowse link
G Nfix nuclear factor I/X involved_in IMP (PMID:17353270) MGI PMID:17353270 NCBI chr 8:85,431,341...85,527,086
Ensembl chr 8:85,426,505...85,526,973 		JBrowse link
G Npr2 natriuretic peptide receptor 2 involved_in IMP (PMID:15572448)
(PMID:15722353)
(PMID:17728275)		 MGI PMID:15572448 PMID:15722353 PMID:17728275 NCBI chr 4:43,629,015...43,651,437
Ensembl chr 4:43,631,935...43,651,244 		JBrowse link
G Pex7 peroxisomal biogenesis factor 7 acts_upstream_of_or_within IMP (PMID:12915479) MGI PMID:12915479 NCBI chr10:19,735,836...19,783,420
Ensembl chr10:19,729,646...19,783,435 		JBrowse link
G Phospho1 phosphatase, orphan 1 acts_upstream_of_or_within IMP (PMID:20684022) MGI PMID:20684022 NCBI chr11:95,715,326...95,722,966
Ensembl chr11:95,715,325...95,722,966 		JBrowse link
G Pthlh parathyroid hormone-like peptide acts_upstream_of_or_within IMP (PMID:8895385) MGI PMID:8895385 NCBI chr 6:147,153,607...147,165,511
Ensembl chr 6:147,153,599...147,165,681 		JBrowse link
G Runx2 runt related transcription factor 2 acts_upstream_of_or_within IMP (PMID:10072783) MGI PMID:10072783 NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684 		JBrowse link
G Scx scleraxis scleraxis bHLH transcription factor involved_in IMP (MGI:4418577|PMID:20059955) UniProt PMID:20059955 MGI:4418577 NCBI chr15:76,341,594...76,343,668
Ensembl chr15:76,341,652...76,343,658 		JBrowse link
G Sik3 SIK family kinase 3 acts_upstream_of_or_within IMP (PMID:22318228) MGI PMID:22318228 NCBI chr 9:45,924,099...46,135,492
Ensembl chr 9:45,924,118...46,135,492 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3, neutral acts_upstream_of_or_within IMP (PMID:17591962)
(PMID:21788370)
(PMID:24505141)		 MGI PMID:17591962 PMID:21788370 PMID:24505141 NCBI chr 8:106,979,180...107,064,597
Ensembl chr 8:106,979,180...107,064,620 		JBrowse link
G Tek TEK receptor tyrosine kinase ISO RGD PMID:11735002 RGD:1601509 NCBI chr 4:94,627,322...94,763,213
Ensembl chr 4:94,627,526...94,763,213 		JBrowse link
G Tmem119 transmembrane protein 119 involved_in IMP (MGI:5543589|PMID:22416756) ARUK-UCL PMID:22416756 MGI:5543589 NCBI chr 5:113,931,790...113,938,457
Ensembl chr 5:113,931,790...113,938,577 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28576
    multicellular organismal process 8916
      ossification 539
        replacement ossification 38
          endochondral ossification 38
Path 2
Term Annotations click to browse term
  biological_process 28576
    developmental process 7377
      anatomical structure development 6849
        multicellular organism development 5442
          system development 4671
            skeletal system development 591
              bone development 259
                bone morphogenesis 117
                  endochondral bone morphogenesis 71
                    endochondral ossification 38
paths to the root