Dlx5 (distal-less homeobox 5) - Rat Genome Database

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Gene: Dlx5 (distal-less homeobox 5) Mus musculus
Analyze
Symbol: Dlx5
Name: distal-less homeobox 5
RGD ID: 10476
MGI Page MGI
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; HMG box domain binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including endochondral ossification; osteoblast differentiation; and positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus. Acts upstream of or within several processes, including animal organ development; face morphogenesis; and positive regulation of macromolecule metabolic process. Located in chromatin; cytoplasm; and nucleus. Is expressed in several structures, including alimentary system; branchial arch; embryo ectoderm; genitourinary system; and sensory organ. Used to study split hand-foot malformation 1. Human ortholog(s) of this gene implicated in split hand-foot malformation 1 and split hand-foot malformation 1 with sensorineural hearing loss. Orthologous to human DLX5 (distal-less homeobox 5); INTERACTS WITH 1,2-dichloroethane; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI385752; homeobox protein DLX-5
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3966,877,801 - 6,882,068 (-)NCBIGRCm39mm39
GRCm39 Ensembl66,877,805 - 6,882,085 (-)Ensembl
GRCm3866,877,801 - 6,882,068 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl66,877,805 - 6,882,085 (-)EnsemblGRCm38mm10GRCm38
MGSCv3766,827,805 - 6,832,068 (-)NCBIGRCm37mm9NCBIm37
MGSCv3666,827,805 - 6,832,068 (-)NCBImm8
Celera67,023,868 - 7,028,132 (-)NCBICelera
Cytogenetic Map6A1NCBI
cM Map62.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IDA)
cytoplasm  (IDA)
nucleoplasm  (TAS)
nucleus  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal alisphenoid bone morphology  (IAGP)
abnormal axon extension  (IAGP)
abnormal basicranium morphology  (IAGP)
abnormal basioccipital bone morphology  (IAGP)
abnormal basisphenoid bone morphology  (IAGP)
abnormal bone ossification  (IAGP)
abnormal brain development  (IAGP)
abnormal cell proliferation  (IAGP)
abnormal cochlea morphology  (IAGP)
abnormal craniofacial bone morphology  (IAGP)
abnormal craniofacial development  (IAGP)
abnormal cranium morphology  (IAGP)
abnormal crista ampullaris morphology  (IAGP)
abnormal crista ampullaris neuroepithelium morphology  (IAGP)
abnormal digit morphology  (IAGP)
abnormal epitympanic recess morphology  (IAGP)
abnormal external auditory canal morphology  (IAGP)
abnormal first pharyngeal arch morphology  (IAGP)
abnormal fontanelle morphology  (IAGP)
abnormal frontal bone morphology  (IAGP)
abnormal frontonasal prominence morphology  (IAGP)
abnormal GABAergic neuron morphology  (IAGP)
abnormal gonial bone morphology  (IAGP)
abnormal head development  (IAGP)
abnormal hindlimb morphology  (IAGP)
abnormal hyoid bone greater horn morphology  (IAGP)
abnormal hyoid bone lesser horn morphology  (IAGP)
abnormal hyoid bone morphology  (IAGP)
abnormal incisor morphology  (IAGP)
abnormal inner ear vestibule morphology  (IAGP)
abnormal interparietal bone morphology  (IAGP)
abnormal intrinsic tongue muscle morphology  (IAGP)
abnormal jaw morphology  (IAGP)
abnormal lacrimal bone morphology  (IAGP)
abnormal larynx morphology  (IAGP)
abnormal lateral nasal prominence morphology  (IAGP)
abnormal malleus morphology  (IAGP)
abnormal mandible morphology  (IAGP)
abnormal mandibular angle morphology  (IAGP)
abnormal mandibular condyloid process morphology  (IAGP)
abnormal mandibular coronoid process morphology  (IAGP)
abnormal mandibular prominence morphology  (IAGP)
abnormal maxilla morphology  (IAGP)
abnormal Meckel's cartilage morphology  (IAGP)
abnormal metatarsal bone morphology  (IAGP)
abnormal middle ear morphology  (IAGP)
abnormal middle ear ossicle morphology  (IAGP)
abnormal mitral cell morphology  (IAGP)
abnormal molar crown morphology  (IAGP)
abnormal molar morphology  (IAGP)
abnormal mouth morphology  (IAGP)
abnormal mylohyoid muscle morphology  (IAGP)
abnormal nasal bone morphology  (IAGP)
abnormal nasal capsule morphology  (IAGP)
abnormal nasal mucosa morphology  (IAGP)
abnormal nasal pit morphology  (IAGP)
abnormal neurocranium morphology  (IAGP)
abnormal occipital bone morphology  (IAGP)
abnormal olfactory bulb granule cell morphology  (IAGP)
abnormal olfactory bulb morphology  (IAGP)
abnormal olfactory bulb periglomerular cell morphology  (IAGP)
abnormal olfactory epithelium morphology  (IAGP)
abnormal olfactory nerve morphology  (IAGP)
abnormal osteoblast differentiation  (IAGP)
abnormal otic capsule morphology  (IAGP)
abnormal outer ear cartilage morphology  (IAGP)
abnormal outer ear morphology  (IAGP)
abnormal palate morphology  (IAGP)
abnormal parietal bone morphology  (IAGP)
abnormal phalanx morphology  (IAGP)
abnormal pharyngeal arch morphology  (IAGP)
abnormal premaxilla morphology  (IAGP)
abnormal pterygoid bone morphology  (IAGP)
abnormal pterygoid muscle morphology  (IAGP)
abnormal pterygoid process morphology  (IAGP)
abnormal rib morphology  (IAGP)
abnormal rostral migratory stream morphology  (IAGP)
abnormal scala vestibuli morphology  (IAGP)
abnormal semicircular canal morphology  (IAGP)
abnormal sensory neuron innervation pattern  (IAGP)
abnormal sexual interaction  (IAGP)
abnormal snout morphology  (IAGP)
abnormal stapedial artery morphology  (IAGP)
abnormal stylohyoid ligament morphology  (IAGP)
abnormal styloid process morphology  (IAGP)
abnormal suckling behavior  (IAGP)
abnormal superior horn of thyroid cartilage morphology  (IAGP)
abnormal tegmen tympani morphology  (IAGP)
abnormal temporal bone squamous part morphology  (IAGP)
abnormal thyroid cartilage morphology  (IAGP)
abnormal tongue muscle morphology  (IAGP)
abnormal tooth mineralization  (IAGP)
abnormal utricular macula morphology  (IAGP)
abnormal vestibular saccular macula morphology  (IAGP)
abnormal vestibular saccule morphology  (IAGP)
abnormal vibrissa morphology  (IAGP)
abnormal viscerocranium morphology  (IAGP)
abnormal vomer bone morphology  (IAGP)
abnormal zygomatic bone morphology  (IAGP)
absent alveolar process  (IAGP)
absent endolymphatic duct  (IAGP)
absent gastric milk in neonates  (IAGP)
absent malleus head  (IAGP)
absent mandibular coronoid process  (IAGP)
absent Meckel's cartilage  (IAGP)
absent molars  (IAGP)
absent olfactory epithelium  (IAGP)
absent palatine bone horizontal plate  (IAGP)
absent posterior semicircular canal  (IAGP)
absent semicircular canals  (IAGP)
absent stapes  (IAGP)
absent superior semicircular canal  (IAGP)
absent vomeronasal organ  (IAGP)
anencephaly  (IAGP)
brachydactyly  (IAGP)
cleft primary palate  (IAGP)
cleft secondary palate  (IAGP)
decreased body size  (IAGP)
decreased bone mineralization  (IAGP)
decreased cochlear coiling  (IAGP)
decreased lateral semicircular canal size  (IAGP)
decreased maxillary shelf size  (IAGP)
decreased tympanic ring size  (IAGP)
delayed bone ossification  (IAGP)
delayed cranial suture closure  (IAGP)
deviated nasal septum  (IAGP)
distended abdomen  (IAGP)
ectopic cartilage  (IAGP)
ectopic cranial bone  (IAGP)
ectrodactyly  (IAGP)
enlarged utricle  (IAGP)
exencephaly  (IAGP)
frontonasal prominence hypoplasia  (IAGP)
fused pharyngeal arches  (IAGP)
hypoactivity  (IAGP)
large anterior fontanelle  (IAGP)
lower jaw to upper jaw transformation  (IAGP)
meteorism  (IAGP)
micrognathia  (IAGP)
monodactyly  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
open neural tube  (IAGP)
otic capsule hypoplasia  (IAGP)
otic vesicle hypoplasia  (IAGP)
palatal shelves fail to meet at midline  (IAGP)
perinatal lethality  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
respiratory distress  (IAGP)
short endolymphatic duct  (IAGP)
short lower incisors  (IAGP)
short mandible  (IAGP)
short maxilla  (IAGP)
short Meckel's cartilage  (IAGP)
short nasal bone  (IAGP)
short nasal septum  (IAGP)
short premaxilla  (IAGP)
short snout  (IAGP)
short styloid process  (IAGP)
short upper incisors  (IAGP)
small interparietal bone  (IAGP)
small lacrimal bone  (IAGP)
small malleus processus brevis  (IAGP)
small maxilla  (IAGP)
small nasal bone  (IAGP)
small olfactory bulb  (IAGP)
small parietal bone  (IAGP)
small presphenoid bone  (IAGP)
small supraoccipital bone  (IAGP)
small trigeminal ganglion  (IAGP)
small vomer bone  (IAGP)
small vomeronasal organ  (IAGP)
syndactyly  (IAGP)
turbinate hypoplasia  (IAGP)
wide cranial sutures  (IAGP)
Wormian bones  (IAGP)
References

Additional References at PubMed
PMID:7907794   PMID:8702182   PMID:8855272   PMID:9022063   PMID:9111364   PMID:9187081   PMID:9247261   PMID:9256352   PMID:9415433   PMID:9733575   PMID:9763476   PMID:9876181  
PMID:10021349   PMID:10075846   PMID:10349636   PMID:10393115   PMID:10433909   PMID:10433912   PMID:10516593   PMID:10556054   PMID:10601039   PMID:10603356   PMID:10632600   PMID:10773441  
PMID:11003836   PMID:11042159   PMID:11061425   PMID:11069141   PMID:11076861   PMID:11084035   PMID:11161479   PMID:11180832   PMID:11217851   PMID:11358480   PMID:11675124   PMID:11748138  
PMID:11782417   PMID:11923006   PMID:12000792   PMID:12086465   PMID:12112878   PMID:12142028   PMID:12193642   PMID:12231626   PMID:12351180   PMID:12397111   PMID:12434331   PMID:12466851  
PMID:12514106   PMID:12514213   PMID:12533617   PMID:12533789   PMID:12571099   PMID:12588849   PMID:12644247   PMID:12670995   PMID:12727448   PMID:12799141   PMID:12810586   PMID:12815054  
PMID:12895028   PMID:12921747   PMID:12948657   PMID:12957859   PMID:14623822   PMID:14654219   PMID:14681194   PMID:14681479   PMID:14695375   PMID:14769946   PMID:14962748   PMID:15053981  
PMID:15105372   PMID:15107405   PMID:15110048   PMID:15173589   PMID:15217369   PMID:15238450   PMID:15306564   PMID:15328018   PMID:15362572   PMID:15363417   PMID:15376319   PMID:15376323  
PMID:15376329   PMID:15383550   PMID:15385160   PMID:15456894   PMID:15499560   PMID:15581864   PMID:15608638   PMID:15618518   PMID:15647918   PMID:15652707   PMID:15677725   PMID:15708565  
PMID:15743757   PMID:15829521   PMID:15936338   PMID:15961523   PMID:16007083   PMID:16141072   PMID:16141073   PMID:16221730   PMID:16267092   PMID:16284245   PMID:16325169   PMID:16330189  
PMID:16341224   PMID:16368934   PMID:16452098   PMID:16537572   PMID:16582099   PMID:16602821   PMID:16613831   PMID:16678814   PMID:16705037   PMID:16707790   PMID:16766712   PMID:16806848  
PMID:16829211   PMID:16839541   PMID:16900517   PMID:16960803   PMID:17027239   PMID:17060321   PMID:17074316   PMID:17085970   PMID:17164413   PMID:17182777   PMID:17241623   PMID:17376983  
PMID:17420000   PMID:17507568   PMID:17555518   PMID:17588208   PMID:17601531   PMID:17652354   PMID:17679093   PMID:17693062   PMID:17804636   PMID:17855431   PMID:17878916   PMID:17928865  
PMID:17964566   PMID:17969168   PMID:17990271   PMID:18056716   PMID:18061570   PMID:18096892   PMID:18160706   PMID:18199583   PMID:18276760   PMID:18287559   PMID:18316591   PMID:18326838  
PMID:18367558   PMID:18377888   PMID:18403408   PMID:18404215   PMID:18412219   PMID:18495817   PMID:18562676   PMID:18572160   PMID:18634775   PMID:18669617   PMID:18684439   PMID:18697905  
PMID:18701439   PMID:18703040   PMID:19004851   PMID:19017795   PMID:19020049   PMID:19027001   PMID:19030180   PMID:19185569   PMID:19235731   PMID:19279136   PMID:19299468   PMID:19386638  
PMID:19393622   PMID:19414008   PMID:19415689   PMID:19419310   PMID:19476657   PMID:19497851   PMID:19540218   PMID:19580868   PMID:19620975   PMID:19777591   PMID:19777594   PMID:19820705  
PMID:19842177   PMID:19913004   PMID:19934017   PMID:19956613   PMID:20036863   PMID:20051123   PMID:20059953   PMID:20181579   PMID:20211142   PMID:20333701   PMID:20392955   PMID:20436479  
PMID:20459789   PMID:20503367   PMID:20510229   PMID:20534536   PMID:20589882   PMID:20639873   PMID:20652952   PMID:20702565   PMID:20824629   PMID:20843790   PMID:20878775   PMID:20939017  
PMID:21048141   PMID:21185278   PMID:21187071   PMID:21194568   PMID:21227998   PMID:21237142   PMID:21270050   PMID:21309073   PMID:21325536   PMID:21362415   PMID:21406180   PMID:21441981  
PMID:21452241   PMID:21465616   PMID:21505076   PMID:21525287   PMID:21558373   PMID:21619873   PMID:21831920   PMID:21873635   PMID:21930923   PMID:21943598   PMID:22154806   PMID:22182523  
PMID:22186731   PMID:22354888   PMID:22411303   PMID:22442009   PMID:22513373   PMID:22547067   PMID:22705977   PMID:22745311   PMID:22821687   PMID:22886599   PMID:22902530   PMID:22912414  
PMID:22914741   PMID:22988430   PMID:23022035   PMID:23034633   PMID:23041177   PMID:23112163   PMID:23201021   PMID:23312518   PMID:23382810   PMID:23425387   PMID:23473983   PMID:23536097  
PMID:23592779   PMID:23648570   PMID:23818325   PMID:23829703   PMID:23863482   PMID:23872235   PMID:23933587   PMID:24089468   PMID:24146773   PMID:24385915   PMID:24491691   PMID:24569166  
PMID:24583262   PMID:24586192   PMID:24639535   PMID:24650709   PMID:24682237   PMID:24692107   PMID:24733577   PMID:24785830   PMID:24899708   PMID:24949938   PMID:24952961   PMID:24996922  
PMID:25071457   PMID:25125027   PMID:25166858   PMID:25178196   PMID:25512300   PMID:25565927   PMID:25626636   PMID:25725491   PMID:25793663   PMID:25805847   PMID:25889273   PMID:25922531  
PMID:25937343   PMID:26123167   PMID:26189100   PMID:26238476   PMID:26512061   PMID:26534985   PMID:26550799   PMID:26677825   PMID:26685160   PMID:26806701   PMID:26953501   PMID:27335460  
PMID:28069742   PMID:28122332   PMID:28219675   PMID:28289129   PMID:28333962   PMID:28455376   PMID:28528976   PMID:28769044   PMID:28794157   PMID:28982687   PMID:29031500   PMID:29068100  
PMID:29140246   PMID:29229773   PMID:29301908   PMID:29352015   PMID:29513653   PMID:29670900   PMID:29852132   PMID:30146317   PMID:30297736   PMID:30401834   PMID:30635555   PMID:30657543  
PMID:30659230   PMID:30770380   PMID:30796806   PMID:30872278   PMID:30889190   PMID:30905259   PMID:31171666   PMID:31340933   PMID:31433982   PMID:31900962   PMID:31915148   PMID:31949165  
PMID:32040930   PMID:32170006   PMID:32260461   PMID:32580935   PMID:32616504   PMID:32868762   PMID:32985705   PMID:33483579   PMID:33492553   PMID:33500348   PMID:33593819   PMID:33723076  
PMID:33795231   PMID:34155146  


Genomics

Comparative Map Data
Dlx5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3966,877,801 - 6,882,068 (-)NCBIGRCm39mm39
GRCm39 Ensembl66,877,805 - 6,882,085 (-)Ensembl
GRCm3866,877,801 - 6,882,068 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl66,877,805 - 6,882,085 (-)EnsemblGRCm38mm10GRCm38
MGSCv3766,827,805 - 6,832,068 (-)NCBIGRCm37mm9NCBIm37
MGSCv3666,827,805 - 6,832,068 (-)NCBImm8
Celera67,023,868 - 7,028,132 (-)NCBICelera
Cytogenetic Map6A1NCBI
cM Map62.83NCBI
DLX5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl797,020,396 - 97,024,950 (-)EnsemblGRCh38hg38GRCh38
GRCh38797,020,396 - 97,024,831 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37796,649,708 - 96,654,143 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36796,487,638 - 96,492,079 (-)NCBINCBI36hg18NCBI36
Build 34796,294,358 - 96,298,794NCBI
Celera791,343,634 - 91,348,072 (-)NCBI
Cytogenetic Map7q21.3NCBI
HuRef791,251,295 - 91,255,732 (-)NCBIHuRef
CHM1_1796,579,739 - 96,584,181 (-)NCBICHM1_1
CRA_TCAGchr7v2795,972,198 - 95,976,639 (-)NCBI
Dlx5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2434,999,139 - 35,003,504 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl434,999,139 - 35,003,407 (-)Ensembl
Rnor_6.0432,387,741 - 32,392,085 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl432,387,741 - 32,392,007 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0432,255,323 - 32,259,589 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4431,778,500 - 31,782,767 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1431,897,039 - 31,901,307 (-)NCBI
Celera430,515,648 - 30,519,914 (-)NCBICelera
Cytogenetic Map4q21NCBI
Dlx5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543213,429,415 - 13,434,258 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543213,429,832 - 13,434,160 (-)NCBIChiLan1.0ChiLan1.0
DLX5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17102,556,636 - 102,561,186 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7102,555,267 - 102,561,186 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0788,972,066 - 88,977,588 (-)NCBIMhudiblu_PPA_v0panPan3
DLX5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11422,080,351 - 22,085,188 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1422,080,699 - 22,084,867 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1421,648,083 - 21,652,478 (-)NCBI
ROS_Cfam_1.01421,897,429 - 21,901,826 (-)NCBI
UMICH_Zoey_3.11422,044,142 - 22,048,532 (-)NCBI
UNSW_CanFamBas_1.01421,779,484 - 21,783,873 (-)NCBI
UU_Cfam_GSD_1.01422,043,227 - 22,047,620 (-)NCBI
Dlx5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511835,346,260 - 35,401,337 (-)NCBI
SpeTri2.0NW_0049365853,462,063 - 3,466,641 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DLX5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl976,639,561 - 76,643,884 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1976,639,915 - 76,643,689 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103226510
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12152,032,933 - 52,092,791 (+)NCBI
ChlSab1.1 Ensembl2152,036,401 - 52,040,903 (+)Ensembl
Vero_WHO_p1.0NW_02366604252,268,203 - 52,315,364 (-)NCBI
Dlx5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248133,760,890 - 3,765,309 (-)NCBI

Position Markers
Dlx5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3866,877,928 - 6,878,491UniSTSGRCm38
MGSCv3766,827,928 - 6,828,491UniSTSGRCm37
Celera67,023,991 - 7,024,555UniSTS
Cytogenetic Map6A1UniSTS
cM Map62.0UniSTS
cM Map62.0UniSTS
AI385752  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3866,878,076 - 6,878,177UniSTSGRCm38
MGSCv3766,828,076 - 6,828,177UniSTSGRCm37
Celera67,024,140 - 7,024,241UniSTS
Cytogenetic Map6A1UniSTS
cM Map62.0UniSTS
Whitehead/MRC_RH661.77UniSTS
MARC_9717-9718:996688547:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3866,881,574 - 6,881,882UniSTSGRCm38
MGSCv3766,831,574 - 6,831,882UniSTSGRCm37
Celera67,027,638 - 7,027,946UniSTS
Cytogenetic Map6A1UniSTS
cM Map62.0UniSTS
DLX5_2316  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3866,877,760 - 6,878,464UniSTSGRCm38
MGSCv3766,827,760 - 6,828,464UniSTSGRCm37
Celera67,023,823 - 7,024,528UniSTS
Cytogenetic Map6A1UniSTS
cM Map62.0UniSTS
Dlx5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6A1UniSTS
Dlx5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6A1UniSTS
cM Map62.0UniSTS
Dlx5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3866,877,849 - 6,878,276UniSTSGRCm38
MGSCv3766,827,849 - 6,828,276UniSTSGRCm37
Celera67,023,912 - 7,024,340UniSTS
Cytogenetic Map6A1UniSTS
Dlx5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3866,881,821 - 6,881,885UniSTSGRCm38
MGSCv3766,831,821 - 6,831,885UniSTSGRCm37
Celera67,027,885 - 7,027,949UniSTS
Cytogenetic Map6A1UniSTS
Dlx5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6A1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
14746985Manh59_mmandible shape 59 (mouse)6120847193Mouse
1357503Nhdlq5_mnon-HDL QTL 5 (mouse)Not determined6121465015Mouse
1301178Lith10_mlithogenic gene 10 (mouse)Not determined6121465015Mouse
10043884Bhr8_mbronchial hyperresponsiveness 8 (mouse)Not determined6121465015Mouse
10044000Mobq9_mmultigenetic obesity QTL 9 (mouse)Not determined6121465015Mouse
12904934Edlmmq4_mextensor digitorum longus muscle mass QTL 4 (mouse)6125514064Mouse
12904942Tammq3_mtibialis anterior muscle mass QTL 3 (mouse)6125514064Mouse
12904955Gmmq3_mgastrocnemius muscle mass QTL 3 (mouse)6125514064Mouse
1301131Chol2_mcholesterol 2 (mouse)Not determined6132144496Mouse
5491191Mobq2_mmultigenic obesity QTL 2 (mouse)Not determined6132144496Mouse
1302024Skull7_mskull morphology 7 (mouse)Not determined6132144496Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
15039372Nmrs22_mNAFLD-associated magnetic resonance shift 22 (mouse)6147633535476335Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300731Smdq3_msegregation of mitochondrial DNA QTL 3 (mouse)Not determined6424920738249326Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
11353836Bmiq1_mbody mass index QTL 1 (mouse)6450382329751334Mouse
11353840Bmiq2_mbody mass index QTL 2 (mouse)6450382345314181Mouse
1357481Aaj2_manxiety in A/J 2 (mouse)Not determined6450382348726677Mouse
1357520Axtq2_manxiety QTL 2 (mouse)Not determined6450382348726677Mouse
11353841Bmiq3_mbody mass index QTL 3 (mouse)6450382348726677Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir200ammu-miR-200a-3pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI19454767
Mir200ammu-miR-200a-3pMirecordsexternal_info{unchanged}NA19454767
Mir141mmu-miR-141-3pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI19454767
Mir141mmu-miR-141-5pMirecordsexternal_info{unchanged}NA19454767

Predicted Target Of
Summary Value
Count of predictions:314
Count of miRNA genes:189
Interacting mature miRNAs:216
Transcripts:ENSMUST00000052609, ENSMUST00000142635
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000052609   ⟹   ENSMUSP00000052559
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl66,877,805 - 6,882,085 (-)Ensembl
GRCm38.p6 Ensembl66,877,805 - 6,882,085 (-)Ensembl
RefSeq Acc Id: ENSMUST00000142635   ⟹   ENSMUSP00000138264
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl66,877,805 - 6,882,068 (-)Ensembl
GRCm38.p6 Ensembl66,877,805 - 6,882,068 (-)Ensembl
RefSeq Acc Id: ENSMUST00000204014
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl66,880,692 - 6,882,082 (-)Ensembl
GRCm38.p6 Ensembl66,880,692 - 6,882,082 (-)Ensembl
RefSeq Acc Id: NM_010056   ⟹   NP_034186
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3966,877,801 - 6,882,068 (-)NCBI
GRCm3866,877,801 - 6,882,068 (-)NCBI
MGSCv3766,827,805 - 6,832,068 (-)RGD
Celera67,023,864 - 7,028,132 (-)NCBI
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_198854   ⟹   NP_942151
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3966,877,801 - 6,882,068 (-)NCBI
GRCm3866,877,801 - 6,882,068 (-)NCBI
MGSCv3766,827,805 - 6,832,068 (-)RGD
Celera67,023,864 - 7,028,132 (-)NCBI
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006504980   ⟹   XP_006505043
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3966,877,801 - 6,881,606 (-)NCBI
GRCm3866,877,801 - 6,881,607 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034186   ⟸   NM_010056
- Peptide Label: isoform 1
- UniProtKB: P70396 (UniProtKB/Swiss-Prot),   Q3TYA7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_942151   ⟸   NM_198854
- Peptide Label: isoform 2
- UniProtKB: P70396 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006505043   ⟸   XM_006504980
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000052559   ⟸   ENSMUST00000052609
RefSeq Acc Id: ENSMUSP00000138264   ⟸   ENSMUST00000142635
Protein Domains
DLL_N

Promoters
RGD ID:6888972
Promoter ID:EPDNEW_M7937
Type:single initiation site
Name:Dlx5_1
Description:Mus musculus distal-less homeobox 5 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3866,882,085 - 6,882,145EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:101926 AgrOrtholog
Ensembl Genes ENSMUSG00000029755 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000052559 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000138264 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000052609 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000142635 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Distal-less_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_metazoa UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HTH_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13395 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:101926 ENTREZGENE
NCBI Gene 13395 ENTREZGENE
Pfam DLL_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeodomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dlx5 PhenoGen
PRINTS HOMEOBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HTHREPRESSR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt DLX5_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TYA7 ENTREZGENE, UniProtKB/TrEMBL
  Q3TZ43_MOUSE UniProtKB/TrEMBL
UniProt Secondary O54876 UniProtKB/Swiss-Prot
  O54877 UniProtKB/Swiss-Prot
  O54878 UniProtKB/Swiss-Prot
  Q9JJ45 UniProtKB/Swiss-Prot