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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:5-bromo-2'-deoxyuridine
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Accession:CHEBI:472552 term browser browse the term
Definition:A pyrimidine 2'-deoxyribonucleoside compound having 5-bromouracil as the nucleobase.
Synonyms:related_synonym: 5-Bdu;   5-Bromodeoxyuridine;   5-Bromodesoxyuridine;   5-Bromouracil deoxyriboside;   5-Bromouracil-2-deoxyriboside;   BrdU;   Bromodeoxyuridine;   Bromouracil deoxyriboside;   Formula=C9H11BrN2O5;   InChI=1S/C9H11BrN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1;   InChIKey=WOVKYSAHUYNSMH-RRKCRQDMSA-N;   SMILES=OC[C@H]1O[C@H](C[C@@H]1O)n1cc(Br)c(=O)[nH]c1=O;   broxuridina;   broxuridine;   broxuridinum
 alt_id: CHEBI:31310;   CHEBI:47713
 xref: Beilstein:4236087;   CAS:59-14-3;   Drug_Central:3042
 xref_mesh: MESH:D001973
 xref: PDBeChem:U33;   PMID:17325220;   PMID:17341060;   PMID:3950402;   Wikipedia:Bromodeoxyuridine


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5-bromo-2'-deoxyuridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef26 Rho guanine nucleotide exchange factor 26 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] affects the expression of ARHGEF26 mRNA CTD PMID:24910943 NCBI chr 2:148,889,405...149,000,538
Ensembl chr 2:146,739,631...146,850,819 		JBrowse link
G Atoh8 atonal bHLH transcription factor 8 decreases expression ISO Bromodeoxyuridine results in decreased expression of ATOH8 mRNA CTD PMID:24910943 NCBI chr 4:105,818,203...105,850,379
Ensembl chr 4:104,259,992...104,292,168 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of BAX mRNA CTD PMID:24910943 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of BIRC5 mRNA CTD PMID:24910943 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of CDKN1A mRNA CTD PMID:24910943 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Ces2c carboxylesterase 2C multiple interactions ISO [Bromodeoxyuridine co-treated with furan] affects the expression of CES2C mRNA CTD PMID:24910943 NCBI chr 1:270,377,201...270,384,768
Ensembl chr 1:260,388,902...260,398,790 		JBrowse link
G Dnase1 deoxyribonuclease 1 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] affects the expression of DNASE1 mRNA CTD PMID:24910943 NCBI chr10:12,005,305...12,030,615
Ensembl chr10:11,498,931...11,501,869 		JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of DUSP6 mRNA CTD PMID:24910943 NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G Dusp8 dual specificity phosphatase 8 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of DUSP8 mRNA CTD PMID:24910943 NCBI chr 1:206,596,912...206,613,728
Ensembl chr 1:197,169,422...197,182,921 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression ISO Bromodeoxyuridine results in increased expression of ELOVL6 mRNA CTD PMID:24910943 NCBI chr 2:220,738,095...220,845,528
Ensembl chr 2:218,063,804...218,171,186 		JBrowse link
G Fam47e family with sequence similarity 47, member E increases expression ISO Bromodeoxyuridine results in increased expression of FAM47E mRNA CTD PMID:24910943 NCBI chr14:15,769,441...15,805,911
Ensembl chr14:15,485,127...15,521,775 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of GCLC mRNA CTD PMID:24910943 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of GDF15 mRNA CTD PMID:24910943 NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression		 ISO [Bromodeoxyuridine co-treated with furan] affects the expression of HMGCR mRNA
Bromodeoxyuridine results in increased expression of HMGCR mRNA		 CTD PMID:24910943 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmox1 heme oxygenase 1 affects abundance
multiple interactions		 ISO HMOX1 protein affects the abundance of Bromodeoxyuridine
[Bromodeoxyuridine co-treated with furan] results in increased expression of HMOX1 mRNA		 CTD PMID:17401437 PMID:24910943 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C multiple interactions ISO [HNRNPC protein binds to HNRNPC protein alternative form] which results in decreased susceptibility to Bromodeoxyuridine CTD PMID:16960656 NCBI chr15:27,253,098...27,282,779
Ensembl chr15:24,779,450...24,809,183 		JBrowse link
G Itga5 integrin subunit alpha 5 increases expression ISO Bromodeoxyuridine results in increased expression of ITGA5 mRNA; Bromodeoxyuridine results in increased expression of ITGA5 protein CTD PMID:7519154 NCBI chr 7:136,358,097...136,381,305
Ensembl chr 7:134,478,968...134,502,837 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of JUN mRNA CTD PMID:24910943 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] affects the expression of MOGAT2 mRNA CTD PMID:24910943 NCBI chr 1:162,933,964...162,957,896
Ensembl chr 1:153,521,815...153,545,756 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 increases expression ISO Bromodeoxyuridine results in increased expression of MSMO1 mRNA CTD PMID:24910943 NCBI chr16:29,747,113...29,764,360
Ensembl chr16:24,980,697...24,998,016 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of MYC mRNA CTD PMID:24910943 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Ngfr nerve growth factor receptor multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of TNFRSF10B mRNA CTD PMID:24910943 NCBI chr10:81,012,077...81,030,305
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 increases expression ISO Bromodeoxyuridine results in increased expression of NMRK1 mRNA CTD PMID:24910943 NCBI chr 1:225,475,975...225,503,414
Ensembl chr 1:216,049,437...216,076,791 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of NQO1 mRNA CTD PMID:24910943 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G P2ry1 purinergic receptor P2Y1 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] affects the expression of P2RY1 mRNA CTD PMID:24910943 NCBI chr 2:147,391,661...147,397,870
Ensembl chr 2:145,241,849...145,248,457 		JBrowse link
G Pax3 paired box 3 increases response to substance ISO PAX3 gene polymorphism results in increased susceptibility to Bromodeoxyuridine CTD PMID:3902948 NCBI chr 9:87,015,960...87,112,531
Ensembl chr 9:79,568,634...79,664,042 		JBrowse link
G Scgb1c1 secretoglobin, family 1C, member 1 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] affects the expression of SCGB1C1 mRNA CTD PMID:24910943 NCBI chr 1:195,922,660...195,925,022
Ensembl chr 1:195,923,803...195,925,022 		JBrowse link
G Slc17a8 solute carrier family 17 member 8 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] affects the expression of SLC17A8 mRNA CTD PMID:24910943 NCBI chr 7:25,881,557...25,936,837
Ensembl chr 7:23,994,217...24,048,079 		JBrowse link
G Sox17 SRY-box transcription factor 17 decreases localization ISO Bromodeoxyuridine results in decreased localization of SOX17 protein CTD PMID:24154490 NCBI chr 5:19,814,345...19,819,859
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Sqle squalene epoxidase increases expression ISO Bromodeoxyuridine results in increased expression of SQLE mRNA CTD PMID:24910943 NCBI chr 7:92,758,175...92,773,049
Ensembl chr 7:90,868,011...90,883,618 		JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of SRXN1 mRNA CTD PMID:24910943 NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G Stmn1 stathmin 1 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of STMN1 mRNA CTD PMID:24910943 NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of TNFRSF12A mRNA CTD PMID:24910943 NCBI chr10:13,211,670...13,213,666
Ensembl chr10:12,689,890...12,709,045 		JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression ISO Bromodeoxyuridine results in decreased expression of TRIB3 mRNA CTD PMID:24910943 NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Tubb2a tubulin, beta 2A class IIa multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of TUBB2A mRNA CTD PMID:24910943 NCBI chr17:31,002,186...31,006,057
Ensembl chr17:30,747,503...30,800,714 		JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of TXNRD1 mRNA CTD PMID:24910943 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Vsnl1 visinin-like 1 decreases response to substance ISO VSNL1 protein results in decreased susceptibility to Bromodeoxyuridine CTD PMID:20419170 NCBI chr 6:39,757,721...39,878,556
Ensembl chr 6:34,038,642...34,159,479 		JBrowse link
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  CHEBI ontology 19909
    role 19880
      biological role 19878
        biochemical role 19586
          antimetabolite 10331
            5-bromo-2'-deoxyuridine 37
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  CHEBI ontology 19909
    subatomic particle 19907
      composite particle 19907
        hadron 19907
          baryon 19907
            nucleon 19907
              atomic nucleus 19907
                atom 19907
                  main group element atom 19846
                    p-block element atom 19846
                      carbon group element atom 19784
                        carbon atom 19781
                          organic molecular entity 19781
                            heteroorganic entity 19540
                              organochalcogen compound 19301
                                organooxygen compound 19216
                                  carbohydrates and carbohydrate derivatives 15321
                                    carbohydrate 15321
                                      carbohydrate derivative 14345
                                        glycosyl compound 13086
                                          N-glycosyl compound 5887
                                            nucleoside 5746
                                              deoxyribonucleoside 2898
                                                2'-deoxyribonucleoside 2251
                                                  pyrimidine 2'-deoxyribonucleoside 357
                                                    5-bromo-2'-deoxyuridine 37
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