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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:5-bromo-2'-deoxyuridine
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Accession:CHEBI:472552 term browser browse the term
Definition:A pyrimidine 2'-deoxyribonucleoside compound having 5-bromouracil as the nucleobase.
Synonyms:related_synonym: 5-Bdu;   5-Bromodeoxyuridine;   5-Bromodesoxyuridine;   5-Bromouracil deoxyriboside;   5-Bromouracil-2-deoxyriboside;   BrdU;   Bromodeoxyuridine;   Bromouracil deoxyriboside;   Formula=C9H11BrN2O5;   InChI=1S/C9H11BrN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1;   InChIKey=WOVKYSAHUYNSMH-RRKCRQDMSA-N;   SMILES=OC[C@H]1O[C@H](C[C@@H]1O)n1cc(Br)c(=O)[nH]c1=O;   broxuridina;   broxuridine;   broxuridinum
 alt_id: CHEBI:31310;   CHEBI:47713
 xref: Beilstein:4236087;   CAS:59-14-3;   Drug_Central:3042
 xref_mesh: MESH:D001973
 xref: PDBeChem:U33;   PMID:17325220;   PMID:17341060;   PMID:3950402;   Wikipedia:Bromodeoxyuridine



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5-bromo-2'-deoxyuridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef26 Rho guanine nucleotide exchange factor 26 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] affects the expression of ARHGEF26 mRNA CTD PMID:24910943 NCBI chr 2:146,740,336...146,850,918
Ensembl chr 2:146,739,631...146,850,819
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 decreases expression ISO Bromodeoxyuridine results in decreased expression of ATOH8 mRNA CTD PMID:24910943 NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of BAX mRNA CTD PMID:24910943 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of BIRC5 mRNA CTD PMID:24910943 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of CDKN1A mRNA CTD PMID:24910943 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Ces2c carboxylesterase 2C multiple interactions ISO [Bromodeoxyuridine co-treated with furan] affects the expression of CES2C mRNA CTD PMID:24910943 NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790
JBrowse link
G Dnase1 deoxyribonuclease 1 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] affects the expression of DNASE1 mRNA CTD PMID:24910943 NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869
JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of DUSP6 mRNA CTD PMID:24910943 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Dusp8 dual specificity phosphatase 8 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of DUSP8 mRNA CTD PMID:24910943 NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression ISO Bromodeoxyuridine results in increased expression of ELOVL6 mRNA CTD PMID:24910943 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Fam47e family with sequence similarity 47, member E increases expression ISO Bromodeoxyuridine results in increased expression of FAM47E mRNA CTD PMID:24910943 NCBI chr14:15,485,537...15,521,599 JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of GCLC mRNA CTD PMID:24910943 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of GDF15 mRNA CTD PMID:24910943 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of GSTA1 mRNA CTD PMID:24910943 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression
ISO [Bromodeoxyuridine co-treated with furan] affects the expression of HMGCR mRNA
Bromodeoxyuridine results in increased expression of HMGCR mRNA
CTD PMID:24910943 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 affects abundance
multiple interactions
ISO HMOX1 protein affects the abundance of Bromodeoxyuridine
[Bromodeoxyuridine co-treated with furan] results in increased expression of HMOX1 mRNA
CTD PMID:17401437 PMID:24910943 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C multiple interactions ISO [HNRNPC protein binds to HNRNPC protein alternative form] which results in decreased susceptibility to Bromodeoxyuridine CTD PMID:16960656 NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183
JBrowse link
G Itga5 integrin subunit alpha 5 increases expression ISO Bromodeoxyuridine results in increased expression of ITGA5 mRNA; Bromodeoxyuridine results in increased expression of ITGA5 protein CTD PMID:7519154 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of JUN mRNA CTD PMID:24910943 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] affects the expression of MOGAT2 mRNA CTD PMID:24910943 NCBI chr 1:153,521,813...153,545,756
Ensembl chr 1:153,521,815...153,545,756
JBrowse link
G Msmo1 methylsterol monooxygenase 1 increases expression ISO Bromodeoxyuridine results in increased expression of MSMO1 mRNA CTD PMID:24910943 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of MYC mRNA CTD PMID:24910943 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 increases expression ISO Bromodeoxyuridine results in increased expression of NMRK1 mRNA CTD PMID:24910943 NCBI chr 1:216,049,350...216,076,792
Ensembl chr 1:216,049,437...216,076,791
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of NQO1 mRNA CTD PMID:24910943 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G P2ry1 purinergic receptor P2Y1 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] affects the expression of P2RY1 mRNA CTD PMID:24910943 NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457
JBrowse link
G Pax3 paired box 3 increases response to substance ISO PAX3 gene polymorphism results in increased susceptibility to Bromodeoxyuridine CTD PMID:3902948 NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042
JBrowse link
G Scgb1c1 secretoglobin, family 1C, member 1 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] affects the expression of SCGB1C1 mRNA CTD PMID:24910943 NCBI chr 1:195,922,660...195,925,022
Ensembl chr 1:195,923,803...195,925,022
JBrowse link
G Slc17a8 solute carrier family 17 member 8 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] affects the expression of SLC17A8 mRNA CTD PMID:24910943 NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079
JBrowse link
G Sox17 SRY-box transcription factor 17 decreases localization ISO Bromodeoxyuridine results in decreased localization of SOX17 protein CTD PMID:24154490 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
JBrowse link
G Sqle squalene epoxidase increases expression ISO Bromodeoxyuridine results in increased expression of SQLE mRNA CTD PMID:24910943 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of SRXN1 mRNA CTD PMID:24910943 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Stmn1 stathmin 1 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of STMN1 mRNA CTD PMID:24910943 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of TNFRSF10B mRNA CTD PMID:24910943 NCBI chr15:44,839,818...44,867,582 JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of TNFRSF12A mRNA CTD PMID:24910943 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression ISO Bromodeoxyuridine results in decreased expression of TRIB3 mRNA CTD PMID:24910943 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Tubb2a tubulin, beta 2A class IIa multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of TUBB2A mRNA CTD PMID:24910943 NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO [Bromodeoxyuridine co-treated with furan] results in increased expression of TXNRD1 mRNA CTD PMID:24910943 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Vsnl1 visinin-like 1 decreases response to substance ISO VSNL1 protein results in decreased susceptibility to Bromodeoxyuridine CTD PMID:20419170 NCBI chr 6:34,038,641...34,159,479
Ensembl chr 6:34,038,642...34,159,479
JBrowse link

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  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          antimetabolite 8546
            5-bromo-2'-deoxyuridine 38
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  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            heteroorganic entity 19278
                              organochalcogen compound 19052
                                organooxygen compound 18998
                                  carbohydrates and carbohydrate derivatives 12342
                                    carbohydrate 12342
                                      carbohydrate derivative 11946
                                        glycosyl compound 10983
                                          N-glycosyl compound 5520
                                            nucleoside 5381
                                              deoxyribonucleoside 2739
                                                2'-deoxyribonucleoside 2221
                                                  pyrimidine 2'-deoxyribonucleoside 340
                                                    5-bromo-2'-deoxyuridine 38
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