Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:phosphagen
go back to main search page
Accession:CHEBI:64618 term browser browse the term
Definition:Any of a group of guanidine or amidine phosphates that function as storage depots for high-energy phosphate in muscle with the purpose of regenerating ATP from ADP during muscular contraction.
Synonyms:xref: Wikipedia:Phosphagen


show annotations for term's descendants           Sort by:
N-phosphocreatine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein]]; Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein] CTD PMID:37648050 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP
ISO		 Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of BAX protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased expression of BAX protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of BAX protein]
Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein]		 CTD PMID:34358621 PMID:34455488 PMID:37597758 PMID:37648050 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions
decreases expression		 EXP Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of BBC3 mRNA]; Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of BBC3 protein]
Phosphocreatine results in decreased expression of BBC3 mRNA; Phosphocreatine results in decreased expression of BBC3 protein		 CTD PMID:37597758 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP
ISO		 Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased expression of BCL2 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]
Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]		 CTD PMID:34455488 PMID:37648050 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO		 7-oxozeanol inhibits the reaction [Phosphocreatine inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]]; Phosphocreatine inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased expression of CASP3 protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased expression of CASP3 protein modified form]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of CASP3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of CASP3 protein modified form]
Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP3 protein]		 CTD PMID:34358621 PMID:34455488 PMID:37597758 PMID:37648050 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 multiple interactions EXP
ISO		 Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased expression of CASP9 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of CASP9 protein]
Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP9 protein]		 CTD PMID:34455488 PMID:37648050 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions EXP Phosphocreatine promotes the reaction [Doxorubicin results in decreased expression of CTGF mRNA] CTD PMID:37597758 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ctnnd1 catenin delta 1 multiple interactions EXP Phosphocreatine promotes the reaction [Doxorubicin results in decreased expression of CTNND1 mRNA] CTD PMID:37597758 NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased expression of CYCS protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of CYCS protein] CTD PMID:34455488 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Foxo3 forkhead box O3 multiple interactions EXP Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of FOXO3 protein] CTD PMID:34358621 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased phosphorylation of GSK3B protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein] CTD PMID:34455488 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions EXP Phosphocreatine promotes the reaction [Doxorubicin results in decreased expression of IGF1R mRNA] CTD PMID:37597758 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Ins1 insulin 1 multiple interactions EXP Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased secretion of INS1 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein] CTD PMID:34455488 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions EXP Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of IRS1 protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased phosphorylation of IRS1 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased phosphorylation of IRS1 protein] CTD PMID:34455488 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Lpl lipoprotein lipase multiple interactions EXP Phosphocreatine inhibits the reaction [Dietary Fats results in decreased activity of LPL protein] CTD PMID:37648050 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 multiple interactions EXP 7-oxozeanol inhibits the reaction [Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of MAP3K7 protein]]; Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of MAP3K7 protein]; Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of MAP3K7 protein] CTD PMID:34358621 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 decreases expression
multiple interactions		 EXP Phosphocreatine results in decreased expression of MAPK7 mRNA
Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of MAPK7 mRNA]		 CTD PMID:37597758 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267 		JBrowse link
G Mapt microtubule-associated protein tau decreases abundance
multiple interactions		 ISO MAPT protein mutant form results in decreased abundance of Phosphocreatine
PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Phosphocreatine]		 CTD PMID:39172838 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Mir143 microRNA 143 multiple interactions
increases expression		 EXP Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of MIR143 mRNA]
Phosphocreatine results in increased expression of MIR143 mRNA		 CTD PMID:37597758 NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of NFE2L2 protein] CTD PMID:34358621 PMID:37597758 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha decreases expression
multiple interactions		 EXP Phosphocreatine results in decreased expression of PDGFRA mRNA
Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of PDGFRA mRNA]		 CTD PMID:37597758 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Ppid peptidylprolyl isomerase D multiple interactions EXP Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of PPID protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased expression of PPID protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of PPID protein] CTD PMID:34455488 NCBI chr 2:164,727,803...164,740,168
Ensembl chr 2:164,727,779...164,740,221 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression		 EXP Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of PTGS2 mRNA]
Phosphocreatine results in decreased expression of PTGS2 mRNA		 CTD PMID:37597758 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions EXP Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of RIPK3 protein] CTD PMID:34358621 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of SOD2 protein] CTD PMID:37597758 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions EXP Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of SOD3 protein] CTD PMID:34358621 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases response to substance
multiple interactions		 EXP STAT3 protein results in increased susceptibility to Phosphocreatine
Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased phosphorylation of STAT3 protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of STAT3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]		 CTD PMID:34455488 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    chemical entity 19867
      atom 19888
        nonmetal atom 19789
          nitrogen atom 18971
            nitrogen molecular entity 18971
              phosphagen 27
                N(omega)-phospho-L-arginine 0
                N-phosphocreatine 27
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      chalcogen 19577
                        oxygen atom 19549
                          oxygen molecular entity 19529
                            hydroxides 19334
                              oxoacid 18791
                                pnictogen oxoacid 14973
                                  phosphorus oxoacid 14576
                                    phosphoric acids 13937
                                      phosphoric acid 13926
                                        phosphoric acid derivative 13847
                                          phosphate 13846
                                            organic phosphate 13835
                                              phosphagen 27
                                                N(omega)-phospho-L-arginine 0
                                                N-phosphocreatine 27
paths to the root