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Antrocin - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Antrocin
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Accession:CHEBI:210866 term browser browse the term
Synonyms:exact_synonym: 7,7-dimethyl-4-methylidene-3,3a,5,6,6a,8,9,10-octahydrobenzo[h][2]benzouran-1-one
 related_synonym: Formula=C15H22O2;   InChI=1S/C15H22O2/c1-10-5-6-12-14(2,3)7-4-8-15(12)11(10)9-17-13(15)16/h11-12H,1,4-9H2,2-3H3;   InChIKey=SDYJYMBMSYYZIC-UHFFFAOYSA-N;   SMILES=O=C1OCC2C13C(C(CCC3)(C)C)CCC2=C
 xref: Chemspider:78444664
 xref_mesh: MESH:C558369

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Antrocin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
decreases expression
multiple interactions		 ISO antrocin analog results in decreased phosphorylation of AKT1 protein
antrocin analog results in decreased expression of AKT1 protein
[antrocin analog co-treated with Sorafenib] results in decreased expression of AKT1 protein		 CTD PMID:36565974 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO antrocin analog results in increased expression of BAX protein; antrocin results in increased expression of BAX
[antrocin analog co-treated with Sorafenib] results in increased expression of BAX protein		 CTD PMID:21158420 PMID:36565974 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO antrocin analog results in decreased expression of BCL2 protein; antrocin results in decreased expression of BCL2 mRNA; antrocin results in decreased expression of BCL2 protein CTD PMID:21158420 PMID:36565974 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO antrocin analog results in decreased expression of BCL2L1 protein; antrocin results in decreased expression of BCL2L1 mRNA; antrocin results in decreased expression of BCL2L1 protein CTD PMID:21158420 PMID:36565974 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO antrocin results in decreased expression of BIRC5 mRNA; antrocin results in decreased expression of BIRC5 protein CTD PMID:21158420 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Casp3 caspase 3 increases cleavage ISO antrocin analog results in increased cleavage of CASP3 protein; antrocin results in increased cleavage of CASP3 protein CTD PMID:21158420 PMID:36565974 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 increases cleavage ISO antrocin analog results in increased cleavage of CASP7 protein CTD PMID:36565974 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO antrocin analog results in decreased expression of CCND1 protein CTD PMID:36565974 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cd44 CD44 molecule decreases expression ISO antrocin analog results in decreased expression of CD44 protein CTD PMID:36565974 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO antrocin analog results in decreased expression of CDK2 protein CTD PMID:36565974 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO antrocin analog results in decreased expression of CDK4 protein CTD PMID:36565974 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cycs cytochrome c, somatic increases expression ISO antrocin results in increased expression of CYCS CTD PMID:21158420 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation ISO antrocin results in decreased phosphorylation of GSK3B protein CTD PMID:21158420 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Klf4 KLF transcription factor 4 decreases expression ISO antrocin analog results in decreased expression of KLF4 protein CTD PMID:36565974 NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Kras KRAS proto-oncogene, GTPase decreases expression ISO antrocin analog results in decreased expression of KRAS protein CTD PMID:36565974 NCBI chr 4:179,916,255...179,949,613 JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases expression
decreases phosphorylation		 ISO antrocin analog results in decreased expression of MAP2K1 protein
antrocin analog results in decreased phosphorylation of MAP2K1 protein		 CTD PMID:36565974 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 decreases phosphorylation ISO antrocin analog results in decreased phosphorylation of MAP2K2 protein CTD PMID:36565974 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation
multiple interactions
decreases expression		 ISO antrocin analog results in decreased phosphorylation of MAPK1 protein
[antrocin analog co-treated with Sorafenib] results in decreased expression of MAPK1 protein
antrocin analog results in decreased expression of MAPK1 protein		 CTD PMID:36565974 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases expression
multiple interactions
decreases phosphorylation		 ISO antrocin analog results in decreased expression of MAPK3 protein
[antrocin analog co-treated with Sorafenib] results in decreased expression of MAPK3 protein
antrocin analog results in decreased phosphorylation of MAPK3 protein		 CTD PMID:36565974 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO antrocin results in decreased phosphorylation of MTOR protein CTD PMID:21158420 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO antrocin analog results in decreased expression of MYC protein CTD PMID:36565974 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nanog Nanog homeobox decreases expression ISO antrocin analog results in decreased expression of NANOG protein CTD PMID:36565974 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO antrocin results in increased cleavage of PARP1 protein CTD PMID:21158420 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 decreases expression ISO antrocin analog results in decreased expression of POU5F1 protein CTD PMID:36565974 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Prom1 prominin 1 decreases expression ISO antrocin analog results in decreased expression of PROM1 protein CTD PMID:36565974 NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases phosphorylation ISO antrocin results in decreased phosphorylation of RELA protein CTD PMID:21158420 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Sox2 SRY-box transcription factor 2 decreases expression ISO antrocin analog results in decreased expression of SOX2 protein CTD PMID:36565974 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
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Term Annotations click to browse term
  CHEBI ontology 19887
    chemical entity 19885
      atom 19885
        nonmetal atom 19809
          oxygen atom 19551
            oxygen molecular entity 19551
              organooxygen compound 19197
                oxacycle 17906
                  naphthofuran 507
                    Antrocin 27
Path 2
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  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    p-block element atom 19824
                      carbon group element atom 19763
                        carbon atom 19760
                          organic molecular entity 19760
                            organic molecule 19713
                              organic cyclic compound 19505
                                organic heterocyclic compound 18875
                                  organic heteropolycyclic compound 18302
                                    organic heterotricyclic compound 15862
                                      naphthofuran 507
                                        Antrocin 27
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